• Childhood Kidney Diseases
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• v.20 no.2
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• pp.83-87
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• 2016

Congenital chloride diarrhea (CLD) is a rare autosomal recessive disease that is difficult to diagnose. CLD requires early treatment to correct electrolyte imbalance and alkalosis and to prevent severe dehydration. Renal injury is clearly associated with defective electrolyte balance induced by CLD, particularly during the first months or years of life. A 7-year-old boy was diagnosed with CLD following detection of a homozygous mutation (c.2063-1G>T) in SLC26A3 at 6 months of age. During treatment with electrolyte supplements, mild proteinuria was detected at 8 months of age, and is still present. Renal biopsy showed the presence of focal renal dysplasia, with metaplastic cartilage and mononuclear cell infiltration, calcification, and fibrosis in the interstitium. Up to two-thirds of the glomeruli exhibited global obsolescence, mostly aggregated in the dysplastic area. In nondysplastic areas, the glomeruli were markedly increased in size and severely hypercellular, with increased mesangial matrix, and displayed segmental sclerosis. The marked glomerular hypertrophy with focal segmental glomerulosclerosis suggested a compensatory reaction to the severe nephron loss or glomerular obsolescence associated with renal dysplasia, with superimposed by CLD aggravating the tubulointerstitial damage.

• Journal of Distribution Science
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• v.13 no.8
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• pp.81-90
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• 2015

Purpose - To vitalize a market or develop a new one, companies frequently release new products into the market, often by shortening the time to market, called the release period. This research aims to investigate the purchase intention behavior of consumers in terms of buying new products at the time of product release based on the release speed. Research Design, Data, and Methodology - The research reviews the influence of relative advantage, complexity, and compatibility among innovative attributes of new products, as proposed by Rogers. Moreover, it examines the moderating effect of the innovative new product attributes in terms of speed of obsolescence of old products and how that influences consumer purchase behavior. Additionally, this study tests the research hypotheses using empirical analysis. Results - The analysis demonstrated that the relative predominance (H1) and suitability (H3) of new products had a statistically significant positive influence on new product purchase intention. However, the complexity (H2) of new products had a statistically significant positive influence on new product purchase intention in contrast to its predicted sign (-). The results of the moderating effect of the old product use period were as follows. H4-1 was not supported since the difference between the path coefficients of the group with the low level old product use period and the group with the high level, represented by the relationship of relative predominance and new product purchase intention, was not statistically significant. H5-1 was also not supported since the difference between the path coefficients of the group with the low level of old product use period and the group with the high level, represented by the relationship of complexity and new product purchase intention, was not statistically significant. However, H4-2 was supported since the difference between the path coefficients of the group with the low level of old product use frequency and the group with the high level, represented by the relationship of relative advantage and new product purchase intention was statistically significant. H5-2 was not supported since the difference between the path coefficients of the group with the low level of old product use frequency and the group with the high level, represented by the relationship of complexity and new product purchase intention, was not statistically significant. H6-2 was also not supported since the difference between the path coefficients of the group with the low level of old product use frequency and the group with the high level, represented by the relationship of compatibility and new product purchase intention, was not statistically significant. Conclusion - According to the results, only H4-2 among the hypotheses on the moderating effect of the old product use period and use frequency was statistically significant. Future research should focus on carrying out a detailed review of the hypothesis on the moderating effect of the old product usage period and frequency, find the cause, and connect this to potential new research.

• Journal of Korean Library and Information Science Society
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• v.18
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• pp.61-90
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• 1991

We analyzed the author's productivity and cited literatures to assess research activities of medical scientists and scientific properties of medical research in Korea by bibliometric research methods. We tested applicability of Lotka's law and analyzed the author's productivity by means of Brookes graphic model. And we measured core journals, aging factors and half-life in medical literatures by the Bradford's law and the law of obsolescence.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.10
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• pp.1117-1123
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• 2014

Nuclear industries have faced unfavorable circumstances such as an obsolescence of the instrumentation and control system, and therefore nuclear society is striving to resolve this trouble fundamentally. FPGAs are currently highlighted as an alternative means for obsolete control systems. Because of the obsolescence-unaffected characteristics, FPGA should be highly reliable in order to be a replacement for PLC (Programmable Logic Controller). Therefore, it is necessary to establish a software development aspect strategy that enhances the reliability of an FPGA-based controller. The reliability analysis including the MTBF (Mean Time Between Failures) is carried out based on the MIL-HDBK-217F. MTBFs are compared with the FPGA-based controller COMMON-Q PLC. As an analysis result, it shows that the reliability of the FPGA-based controller is better than or equal to that of PLC.

• Journal of Korean Library and Information Science Society
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• v.39 no.4
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• pp.377-395
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• 2008

This article aims to help decide until when a library has to hold journal volumes for user efficiency by measuring the value of academic journals to find the frequency of journal use over the elapsed time based on the half-life index-number of literature obsolescence by Burton & Kebler. Four general subjects categories in science was analyzed. (4 detailed subjects in mathematics, 12 in physics, 12 in chemistry, 14 in technology was selected.) As a result, citation ages are $20{\sim}29$ years in mathematics, $8{\sim}11$ in physics, chemistry, and technology. Average half-life indexes are 11.22 year in mathematics, 7.5 in physics, 8.4 in chemistry, and 8.88 in technology.

• Journal of Labour Economics
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• v.26 no.3
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• pp.29-47
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• 2003

The study analyzes how effective the Government Internship Program has been on accumulation of the human capital. The Program was designed under the foreign exchange crisis to support the new, but unemployed graduates with MA or Ph.D degree in the science and the engineering fields. The survey data is collected from the participants in the Program. The Tobit model is estimated to find the economic effects of the Program in terms of the rate of return of investment in the human capitals of the intern researchers. Considering that the Program is tentative and that the human capitals of the participants are easily obsolescent, the rate of return is observed to be substantially large. These results imply that the Internship Program has been successful in terms of providing not only the researchers with the opportunity to accumulate the human capital by means of the on-the-job-training, but also the institutes or the firms with the opportunity to utilize the high-quality researchers at the low cost.

• Proceedings of the Korean Nuclear Society Conference
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• 1995.10a
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• pp.153-158
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• 1995

All of the nuclear power plants in Korea we operating with analog instrumentation and control (I&C) equipment which are increasingly faced with frequent troubles, obsolescence and high maintenance expenses. Electrical and computer technology has improved rapidly in recent years and has been applied to other industries. So it is strongly recommended we adopt modern digital and computer technology to improve plant safety and availability. The advanced I&C system, namely, Integrated Intelligent Instrumentation and Control System (I$^3$CS) will be developed for beyond the next generation nuclear power plant. I$^3$CS consists of three major parts, the advanced compact workstation, distributed digital control and protection system including Automatic Start-up/shutdown Intelligent Control System (ASICS) and the computer-based alarm processing and operator support system, namely, Diagnosis, Response, and operator Aid Management System (DREAMS).

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1029-1033
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• 2004

Concern over the negative environmental impacts associated with the production, use and End-of-Life(EoL) of cellular phones is particularly high due to large production volumes and characteristically short time scales of technological and stylistic obsolescence. Therefore we have to research the environment-friendly technologies and the recycling methods. This paper introduces an improvement of cellular phone remanufacturing processes and develops the Directive of DFE(Design for Environment) for the remanufacturing of a cellular phone. Then We discuss the results of the comparative evaluations.

• Nuclear Engineering and Technology
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• v.28 no.4
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• pp.359-365
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• 1996

Upgrade of nuclear power plant I&C systems by using digital technology has been implemented to overcome the obsolescence of existing equipment and improve plant availability in many advanced countries. For upgrade of the Plant Protection System(PPS) based on conventional analog technology in the UCN 3&4 and YGN 5&6, French modernized Digital Integrated Protection System(DIPS) with proven technology is reviewed and evaluated for the adaptability into PPS. This paper contains the results of feasibility study for the design of digital PPS using French DIPS technology. Based on the results of evaluations, the system architecture of digital PPS is designed and described.

• Journal of Korea Technology Innovation Society
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• v.3 no.1
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• pp.139-153
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• 2000

The aim of this paper is to provide a new model to evaluate the quantitative value of technology(nonfinancial benefits). This new model is based on the technology stock(technology level) ac-quired in R&D process. The model can explain the quantitative relation between the technology stock(level) and the market value of technology as considering the R&D expenditure to acquire technologies above a certain level(>70%) in comparison with the advanced country and the cost to prevent the technology obsolescence. The value of non-destructive testing technology which is one of the electric power technology is measured quantitatively as a case study.