• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.2
• /
• pp.519-525
• /
• 2016

Background: The objective of this study was to report the types and relative frequency of oral malignancies and precancer in the Jazan region of Saudi Arabia during the period 2009-2014. Materials and Methods: Pathology reports were retrieved from the archives of Histopathology Department, King Fahd hospital in Jazan. Demographic data on tobacco habits, clinical presentation and histologic grading of oral precancer and cancer cases were transcribed from the files. Results: 303 (42.7%) oral pre-malignant and malignant cases were found out of 714 oral biopsy lesions. A pathology diagnosis of squamous cell carcinoma (85.1%) was most frequent, followed by premalignant lesions/epithelial dysplasia (8.6%), verrucous carcinoma (3.3%) and malignancy of other histological types (3%) such as ameloblastic carcinoma, salivary gland malignancy and sarcomas. Oral squamous cell carcinoma was predominant in females with a male to female ratio of 1:1.9. Patient age ranged from 22 to 100 years with a mean of $65{\pm}13.9$. Almost 44.6% of oral cancer had occurred after 65 years of age. Only 16.3% cases were reported in patients younger than 50 years, predominantly females. The majority of female patients had the habit of using shammah with a long duration of usage for more than 45 years. Buccoalveolar mucosa (52.3%) was the common site of involvement followed by tongue/floor of the mouth (47.7%) and clinically presented mostly as ulceration/swelling clinically. Moderately differentiated tumours (53.9%) were common followed by well differentiated (32.2%) and poorly differentiated tumours (5.8%). The prevalence of oral verrucous carcinoma (3.3%) was comparatively low with an equal distribution in both males and females. Both bucco-alveolar mucosa and tongue were predominantly affected. Oral precancer/epithelial dysplasia (8.6%) was common in females with a shammah habit. Bucco-alveolar mucosa was commonly involved and clinically presented mostly as white/red patches. Most cases were mild followed by moderate and severe dysplasia. Tumours of other histological types (3%) include 1 ameloblastic carcinoma, 3 malignant salivary gland tumours and 5 sarcomas. Conclusions: In this study, it was found that oral cancers reported in the pathology service to be a common occurrence. This study reconfirms previous reports of the high burden of oral cancer in this population This indicates that conventional preventive programs focused on oral cancer are in need of revision. In addition, further research into identifying new risk factors and molecular markers for oral cancer are needed for screening high risk individuals.

• Journal of Korean society of Dental Hygiene
• /
• v.10 no.6
• /
• pp.1049-1059
• /
• 2010

Objective : The purpose of this study was to examine the relationship of the general characteristics of parents to their children's oral health care. The subjects in this study were 117 parents and their children who resided in rural communities in the region of K. Methods : A survey was conducted with the consent of the parents from July 1 to 30, 2010. As for the survey on the children, the children who were in the lower grades were interviewed, and the upper graders filled out the questionnaires in person. A frequency analysis was carried out to find out the general characteristics of the parents and children, and x2-test was utilized to grasp the links between the general characteristics of the parents and the children's oral health care. A SPSS WIN 12.0 program was employed to analyze all the collected data. The findings of the study were as follows: Result : 1. As a result of investigating the relationship of the occupation of the parents to the children's regular dental checkup, the 71.8 percent of the entire children didn't get a dental checkup on a regular basis. The biggest percentage of the children of the self-employed parents(100%) got a regular dental checkup, and 90.9 percent of the children of the government workers did that(p<.05). 2. As a result of checking the relationship of the occupation of the parents to the children's dental-caries experiences, 39.3 percent of the whole children had no such experiences. The largest percentage of the children of the company employees(51.9%) had dental-caries experiences(p<.05). 3. Concerning the links between the academic credential of the parents and the children's toothbrushing method, the biggest percentage of the children(40.2%) brushed their teeth up and down. The largest rate of the children whose parents were high-school graduates(41.5%) brushed their teeth in that way(p<.05). 4. Regarding the links between the toothbrushing time of the parents and the children's view, 43.6 percent found their parents to take good care of their teeth to make them clean. 60 percent whose parents brushed their teeth after having breakfast and dinner took the best view(p<.001). 5. As for the oral-health education experiences of the parents and a time for the children's change of toothbrushes, 29.1 percent changed their toothbrushes every two months, and 29.1 percent did that not on a regular basis but when the bristles of their toothbrushes got bent(p<.05). Conclusions : The above-mentioned findings suggest that in order to promote children's oral health in consideration of the characteristics of their parents, children should be urged to get a regular dental checkup, and the development of oral-health education programs in which parents and children can participate together is urgently required.

• Korean Journal of Veterinary Service
• /
• v.31 no.1
• /
• pp.1-16
• /
• 2008

Salmonella infections cause the disease in pigs but also some zoonotic Salmonella serotypes can be transmitted to human through swine products, resulting in food poisoning. The objective of this study was to investigate the bacteriological prevalence and detection of invA gene using Salmonella specific polymerase chain reaction (PCR), the epidemiological characteristics related to Salmonella strains cultured from pig samples in Gangwon areas using serotyping, random amplified polymorphic DNA (RAPD) and pulsed field gel electrophoresis (PFGE) methods. During the period of November 2001 through April 2002, 1,174 ileocecal lymph node were collected from the slaughtered pigs raised in 38 farms located in Gangwon province. The samples were submerged in boiling water and macerated in saline and lymph node homogenates were inoculated into Tetrathionate broth with iodine (TTB, Difco, 0.5% iodine was added) for enrichment growth. Then additional tests were performed using several mediums, and suspects were identified by API 20E kit (BioMerieux) and PCR. Of total 1,174 samples from 38 farms, 44 (3.7%) were isolated as Salmonella spp from 13 farms (34.2%). Of 44 isolates, 31 were in Yangyang region, followed by 9 in Goseong, 2 in both Gangneung and Sokcho. However, there was no difference in regional isolation frequency. All isolates have a 521bp amplified product in Salmonella specific PCR with primer invA which encodes in proteins for invasion of epithelial cells. Of 44 recovered serotypes, 23 (52.3%) were S Eingedi, 10 (22.7%) S Schwarzengrund, 9 (20.5%) S Typhimurium, and 2 (4.5%) S Mbandaka. In RAPD analysis, there appeared to be unique bands distinguishing each serotype, although similarities exist between the different serotypes. Four serotypes of 44 Salmonella isolates appeared to fall into 14 different RAPD types. In PFGE analysis, 9 S Typhimurium were tested with XbaI enzyme and SpeI enzyme. The combination of results obtained with two enzymes subdivided the 9 S Typhimurium into 4 PFGE types.

• Journal of Bio-Environment Control
• /
• v.23 no.2
• /
• pp.95-108
• /
• 2014

The objective of this study is to develop the plastic greenhouse models which are structurally safe under the weather condition of Seongju and have the dimensions suitable for oriental melon cultivation as well. To grasp the structural features of greenhouses in Seongju, the field survey was conducted on 406 farmhouses which included 2,068 greenhouses. The field survey showed that the roof shape of arch type accounted for the highest rate, but recently even span or peach type became more popular and the width and height of greenhouse tended to increase as the period of use was short. The relationship of the width, ridge height and eaves height were established based on field survey data. Using climate data of Gumi adjacent to Seongju, the regressions were determined for the design wind speed and design snow depth depending on recurrence period. To design the greenhouse models against weather disasters in Seongju, the optimal design loads are 23.7 cm of snow depth and $33.8m{\cdot}s^1$ of wind speed. As the design results, four models of single-span greenhouse, two models of double-span greenhouses including extension were developed.

• Clinical and Experimental Reproductive Medicine
• /
• v.37 no.1
• /
• pp.25-31
• /
• 2010

Objective: X inactivation is the silencing one of the two X chromosomes in female mammals for gene dosage on the X-chromosome between female and male. X inactivation is controlled by X inactive-specific transcript (XIST) gene, untranslated RNA. XIST is expressed only from the inactive X (Xi), not expressed from the active X (Xa). The Xist promoter is methylated on the silent Xist allele on the Xa in somatic cells, and less methylated on the Xist-expressing Xi. We investigated the difference of XIST methylation pattern of the promoter and 5'-region of XIST from male (XY) and female (XX) subjects. Methods: The direct quantification of XIST methylation is required for clinical application of normal XX and XY blood. Methylation percentage of eight CpG sites (-1696, -1679, -1475, -1473, -1469, +947, +956, +971) of XIST gene were diagnosed by pyrosequencing. Results: We directly quantitated the methylation percentage of the promoter and 5'-end of XIST by pyrosequencing. The average methylation percentages at CpG6-8 sites (+947, +956, +971) were 45.2% at CpG6, 49.9% at CpG7, and 44.2% at CpG8 from normal female and normal male were 90.6%, 96.7%, 87.8%, respectively. Nether CpG 1-5sites (-1696, -1679, -1475, -1473, -1469) had any effect on XX and XY. Conclusion: This method is sensitive for quantifying the small percentage change in the methylation status of XIST, and may be used for diagnosis.

• Animal Bioscience
• /
• v.36 no.3
• /
• pp.484-491
• /
• 2023

Objective: The aim of this trial was to investigate the effect of supplementation and withdrawal of selenium-enriched kale sprouts (SeKS) on productivity and egg Se concentration of laying hens. Selenium from commercial Se-enriched yeast (SeY) was used as a comparative Se source. Methods: One-hundred and eighty 61-week-old laying hens were randomly divided into 5 treatment groups with 4 replicates (9 hens each) in a 2×2+1 Augmented Factorial Experiment in a completely randomized design. The experimental diets were basal diet, basal diet supplemented with 0.2 and 0.4 mg Se/kg from SeKS and SeY, respectively. The 8-week feeding trial was divided into 2 periods, namely the Se supplemental period (week 1 to 4) and the Se withdrawal period (week 5 to 8). Results: Productive performance, egg quality and egg Se concentration of laying hens were not affected by sources of Se (SeKS and SeY) during both, the Se supplemental and withdrawal periods. Egg production and egg Se concentration increased (p<0.05) with increasing levels of Se supplementation. The egg Se concentration increased and reached a peak 1 week after Se supplementation. However, concentration of Se in eggs of hens fed Se from both sources decreased rapidly from the second week of the Se withdrawal period to reach the same egg Se concentration of hens fed the basal diet by the fourth week of the Se withdrawal period. Conclusion: The efficacy of Se from SeKS on productivity and egg Se concentration in laying hens was comparable to commercial SeY. Thus, SeKS can provide an alternate organic Se source for production of Se-enriched eggs.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.21 no.4
• /
• pp.221-228
• /
• 2019

The effects of wind speed on the temperature change during day time could be insignificant in a region with a complex terrain. The objective of this study was to derive empirical relationship between solar radiation and hourly temperature under a windy condition for the period from sunrise to sunset in order to improve hourly air temperature at a site-specific scale. The deviation of the temperature measurements was analyzed along with the changes of the hourly sunlight at weather observation sites located on the east and west slopes under given wind speed. An empirical model where wind speed use used as an independent variable was obtained to quantify the solar effects on the temperature change (MJ/㎡). This model was verified estimating the hourly temperature during the daytime (0600-1900 h) at 25 weather observation sites located in the study area that has complex topography for the period from January to December 2018. The mean error (ME) and root mean square error (RMSE)of the estimated and measured values ranged from -0.98 to 0.67 ℃, and from 0.95 to 2.04 ℃, respectively. The daytime temperature at 1500 h were estimated using new and previous models. It was found that to the model proposed in the present study reduced the measurement errors of the hourly temperature in the afternoon in comparison with the previous model. For example, the ME and RMSE of the previous model were (ME -0.91 ℃ and 1.47 ℃, respectively. In contrast, the values of ME and RMSE were -0.45 ℃ and 1.22 ℃ for the new model, respectively. Our results suggested that the reliability of hourly temperature estimates at a specific site could be improved taking into account the effect of wind as well as solar radiation.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.53 no.1
• /
• pp.64-69
• /
• 2008

The objective of experiment was to investigate the effects of planting density on growth and yield of vegetable soybean, and to clarify the optimum planting density of vegetable soybean in the middle west region of Korea. The field experiment with 4 levels of planting density was carried out at Yesan area in $2005{\sim}2006$. The days from seeding to flowering and the days from seeding to harvesting and lodging were not significantly different among planting distance. The stem length was increased as planting distance was shortened but the number of node, branch, pod per branch, pod per individual, weight of stem and pod, one hundred pod weight and rate of 2+3 seed per pod were decreased as planting density was increased. The size of vegetable soybeans was not significantly different among planting distance, but the harvest index of vegetable soybean was decreased as planting distance was shortened. Yield of vegetable soybean was increased as planting distance was decreased. However, the approriate densities for stem and pod weight per a plant, number of pod per a branch and the vegetable soybean yield of 2+3 seed per pod were different from that density. The optimal planting distance of varieties was $60{\sim}25\;cm$ in Sunheukkong and Ilpumgeomjeongkong and was $60{\sim}35\;cm$ in Galmikong.

• Journal of Trauma and Injury
• /
• v.26 no.4
• /
• pp.273-279
• /
• 2013

Purpose: In patients with splenic trauma, Computed Tomography (CT) scan is helpful in selecting treatment options and evaluating resolution after NOM (Non-Operative Management). The purpose of this study was to suggest a CT based hemoperitoneum (HP) scoring system that can easily be used by clinicians to evaluate the severity of injury and recovery. Methods: A retrospective review of patients with splenic trauma admitted to our hospital between May 2003 and January 2013 was conducted. Patients diagnosed with isolated spleen injury who had a CT scan on admission were included. 1 or 2 points were given according to location and amount of hematoma in the CT image. Using the existing ultrasonography (US) based HP scoring system, the same method was applied to obtain our CT based HP scoring (CBHS) system, which ranges from 0 to 8 points. The CBHS system can be easily used by clinicians for a quick assessment of splenic injury. Results: Of the 39 patients meeting the inclusion criteria, 6 patients were managed operatively and 33 nonoperatively. There was a significant difference in CBHS between the OM (operative management) group and the NOM group.(p=0.03) CBHS showed correlation with Hb (hemoglobin), Hct (hematocrit), spleen injury grade(AAST), and Hounsfield unit of ROI (Region of interest). (p=0.17, p=0.18, p<0.000, p=0.02, respectively) After successful NOM with stabilized Hb level, the amount of hemoperitoneum was scored in the follow-up CT. CBHS demonstrated correlation with decreased spleen injury grade, decreased Hounsfield unit of ROI (Region of interest) (p=0.039, p=0.049, respectively), and also objectively reflected patient recovery. Conclusion: CBHS can be used as an objective and intuitive tool for clinicians in grading the severity of splenic injury by scoring the amount of hemoperitoneum, and in assessing recovery.

• The Journal of Internal Korean Medicine
• /
• v.26 no.2
• /
• pp.440-452
• /
• 2005

Objective: In the winter of 2002, severe acute respiratory syndrome(SARS) began to spread throughout the world. More than 5,000 cases were reported in China, including over 1,700 cases in Hong Kong Special Administrative Region(Hong Kong SAR). The total number of cases reported from Canada and Singapore was more than 200. The total number of SARS cases world-wide reached 8,437 with incidences in 29 counties. Mortality from SARS is estimated at $10{\sim}12%$. When the SARS outbreak occurred in China, the State Administration of Traditional Chinese Medicine of China immediately initiated clinical research projects on the use of integrated herbal medicine and Western medicine for treating SARS. and, in Hong Kong SAR, research on the use of herbal medicine for the prevention and treatment of SARS. Reports were released during convalescence. The objective of this study is to overview twelve clinical SARS reports of WHO on the treatment of SARS with herbal medicine and evaluate the efficacy and safety of treatment of SARS with herbal medicine, and further to share experiences and knowledge of the treatment of SARS. Methods: Twelve clinical reports about SARS from the WHO were selected, overviewed and evaluated for efficacy and safety of treatments of SARS. Results and Conclusion: Twelve clinical reports about SARS showed that the integrated treatment may have advantages, and the advantages are reflected in the following findings: Firstly, herbal medicine is not targeted only at a specific etiology or a certain pathological link, but also at the pathological status of the patients at that particular time. Therefore, comprehensive readjustment was made through various angles, targets and channels to restore the balance of the body. Secondly, there are advantages in the differentiation of the disease and the treatment. Based on the various symptoms, herbal medicine enables the physician to adopt the most suitable principle, provide individual treatment, and to administer medicine in accordance with the actual process and nature of the illness. Thirdly, there are advantages in the results of the treatment; herbal medicine can relieve symptoms, promote absorption of lung inflammation, improve the degree of blood oxygen saturation, regulate immunological functions, reduce the required dosage of glucocorticoid and other Western medicines, and reduce case fatality rate, in addition to lowering the cost of treatment.