• Title/Summary/Keyword: Obesity prevention

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Obesity and Obese-related Chronic Low-grade Inflammation in Promotion of Colorectal Cancer Development

  • Pietrzyk, Lukasz;Torres, Anna;Maciejewski, Ryszard;Torres, Kamil
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4161-4168
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    • 2015
  • Colorectal cancer (CRC) is a worldwide health problem, being the third most commonly detected cancer in males and the second in females. Rising CRC incidence trends are mainly regarded as a part of the rapid 'Westernization' of life-style and are associated with calorically excessive high-fat/low-fibre diet, consumption of refined products, lack of physical activity, and obesity. Most recent epidemiological and clinical investigations have consistently evidenced a significant relationship between obesity-driven inflammation in particular steps of colorectal cancer development, including initiation, promotion, progression, and metastasis. Inflammation in obesity occurs by several mechanisms. Roles of imbalanced metabolism (MetS), distinct immune cells, cytokines, and other immune mediators have been suggested in the inflammatory processes. Critical mechanisms are accounted to proinflammatory cytokines (e.g. IL-1, IL-6, IL-8) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$). These molecules are secreted by macrophages and are considered as major agents in the transition between acute and chronic inflammation and inflammation-related CRC. The second factor promoting the CRC development in obese individuals is altered adipokine concentrations (leptin and adiponectin). The role of leptin and adiponectin in cancer cell proliferation, invasion, and metastasis is attributable to the activation of several signal transduction pathways (JAK/STAT, mitogen-activated protein kinase (MAPK), phosphatidylinositol 3 kinase (PI3K), mTOR, and 5'AMPK signaling pathways) and multiple dysregulation (COX-2 downregulation, mRNA expression).

A Research of Body Size Analysis and Graphing in 20yrs Korean Women (20대 한국 여성의 체위 분석과 도식화 연구)

  • Kim, Dong-Il;Park, Hyun-Jung
    • The Journal of Korean Obstetrics and Gynecology
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    • v.21 no.1
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    • pp.179-198
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    • 2008
  • Purpose: Obesity is already a major clinical problem in Korea, so obesity prevention and treatment practices are gradually interested in Korean Medicine doctors. Moreover subjective body shape image entered as a important medical topic recently. To make a graph system for clinical tool which based on the Korean national standard physical scale. Methods: Physical data of the girth of upper arm, abdomen, hip, buttock, flank, calf, and body weight were statistically analyzed, which collected through the fifth national standard physical scale research. And then reviewed those statistical validation. Results: Relationship of the each body scale data and those graphs were fit and right statistically. Conclusion: These new achieved graph system of Korean standard body scales could be adopt as a useful clinical tool for body image related patients such as obesity, PCOD and postpartum patient.

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Predictors of Obesity and Physical Health Complaints Among 911 Telecommunicators

  • Lilly, Michelle M.;London, Melissa J.;Mercer, Mary C.
    • Safety and Health at Work
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    • v.7 no.1
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    • pp.55-62
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    • 2016
  • Background: This study aims to: (1) examine rates of obesity and physical health complaints among 911 telecommunicators; and (2) document the role of emotion dysregulation, psychological inflexibility, duty-related distress and dissociation, and psychopathology in predicting obesity and physical health complaints in this population. Methods: The sample consisted of 911 telecommunicators from across the country (N = 758). Participants completed an online survey assessing their mental and physical health functioning. Results: A total of 82.5% of the sample reported a body mass index that fell within the overweight or obese category and an average of 17 physical health complaints within the past month. Peritraumatic reactions (distress and dissociation), emotion dysregulation, and psychological inflexibility had effects on physical health largely through psychopathology (alcohol abuse, post-traumatic stress disorder, and depression). Conclusion: Development of adapted prevention and intervention efforts with this population is needed.

Prevalence and Correlates of Obesity in Elementary School Students of Daejeon City (대전지역 일부 초등학생의 비만수준과 관련 요인)

  • Lee, Tae-Yong;Lee, Jae-Hun;Kwon, Kyoung-Hee;Shin, Eun-Sook;Kim, Soon-Young;Nam, Hae-Sung
    • Korean Journal of Health Education and Promotion
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    • v.23 no.3
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    • pp.37-51
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    • 2006
  • Objectives: The objective of this study is to investigate the relation between the obesity prevalence of elementary school students and some factors such as socio-demographic factors, parent's obesity, diet habit and physical activity. Methods: The students of the fourth(443), fifth(405) and sixth grade(417) at six elementary schools in the school district of Daejeon metropolitan city were sample-surveyed and classified into a normal group, a non-intensive obesity group, and a highly intensive obesity group. Results: 1. The obesity rate of the elementary school students in the school district of Daejeon metropolitan city was total 14.2%. 2. The obesity rate of students with parents who had high BMI was notably higher than the other groups. 3. Diet factors such as eating fast, always eating one more, liking fatty food and the frequency of snacks were more critical than physical activity factors in relation to school children's obesity. Conclusions: From the above evidences, it is apparent that the obesity of elementary school students have strong relations with eating habits. It is needed that obesity prevention program such as effective meal guidance in addition to intense physical activities is included in the curriculums of health education for elementary school students.

Relation of obesity-related attitudes, knowledge, and eating behaviors with body weight and body shape satisfaction in $5^{th}$-grade Korean children

  • Lee, Seung-Min;Ahn, Hong-Seok
    • Nutrition Research and Practice
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    • v.1 no.2
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    • pp.126-130
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    • 2007
  • Obesity is a worldwide epidemic problem. The downward trend of an obesity onset age calls for research efforts on how to develop useful nutrition educational programs for children to maintain adequate body weight. Understanding the roles of objective and subjective body status in obesity-related attitudes, knowledge, and behaviors can provide important information. The current study aimed to examine obesity-related attitudes and knowledge and practices of eating behavior guidelines in relation to obesity and body shape satisfaction among children. The gender effect in the relations was also investigated. A self-administered survey was conducted with 260 fifth grade children at 2 public elementary schools in the suburbs of Seoul. Information on demographics, body size, body satisfaction, obesity-related attitudes and knowledge, and eating behaviors was collected. Study findings from one-way analysis of variance tests indicated no differences in mean scores of the attitudes, knowledge, and eating behaviors across the levels of obesity for both gender. The levels of body shape satisfaction was, however, found to be significantly related with the attitudes and eating behaviors in girls, while no such relation was seen in boys. Girls with lower body shape dissatisfaction had significantly more negative attitudes toward obesity which was not translated into practice of healthy eating behaviors. That is, contrary to general expectation, the level of practicing the eating behavior guidelines was significantly lower in those girls. While underlying reasons for this observation is not fully answered, gender-specific, body satisfaction-stratified, and behavior-focused approach in designing obesity prevention programs for elementary school girls is suggested efficient and useful.

Comparative evaluation of obesity-related parameters in junior sumo wrestlers and children with obesity

  • Ogawa, Miori;Sagayama, Hiroyuki;Tamai, Shinsuke;Momma, Reiko;Hoshi, Daisuke;Uchizawa, Akiko;Ichikawa, Go;Arisaka, Osamu;Watanabe, Koichi
    • Korean Journal of Exercise Nutrition
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    • v.25 no.3
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    • pp.36-43
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    • 2021
  • [Purpose] Exercise is a key factor in preventing obesity and metabolic syndrome. Sumo wrestlers increase their body size from childhood for athletic advantage; however, the risk of metabolic syndrome in junior sumo wrestlers is undetermined. Preventive measures against pediatric obesity should be initiated during childhood to prevent obesity in adulthood, considering its high global incidence. We comparatively evaluated the risk factors for metabolic syndrome in junior sumo wrestlers and children with obesity. [Methods] We enrolled 70 male children (age 9-17 years [sumo group, n = 14] and 9-14 years [other sports and non-exercise groups, n = 28 each]) and evaluated their anthropometric parameters (height, weight, body mass index z-score, obesity rate, waist circumference, waist to height ratio) and hematological parameters (total, low-density, high-density, and non-high-density lipoprotein-cholesterol; triglycerides; plasma glucose, and glycated hemoglobin levels). [Results] The BMI z-score, obesity rate, waist circumference (p < 0.05, along with the non-exercise group), and systolic blood pressure were significantly higher and the high-density cholesterol level was lower in the sumo group than in the other sports group (p < 0.05). The waist to height ratio was significantly higher in the non-exercise group than in the other sports group (p < 0.05). No significant difference was found in other blood lipid, plasma glucose (significantly lower level than the reference range in the sumo group, p < 0.05), and glycated hemoglobin (within the reference range in all groups) levels among the three groups. [Conclusion] Junior sumo wrestlers had a larger body size and higher blood pressure than children with obesity who exercised regularly. This provides direction for future research into targeted preventive interventions against metabolic syndrome for junior sumo wrestlers with large body size.

Oriental Medicines Effects on Cure and Prevention of an Obesity(VII) (비만치료 및 예방에 대한 한약의 효능 연구(VII) -체감행혈억이인탕가옥미가 비만유도 흰쥐의 생화학적 변화에 미치는 영향-)

  • Kim Sang Chan;Kwon Young Kyu;Kim Youn Sub;Byun Sung Hui
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.5
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    • pp.1001-1008
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    • 2002
  • This present study was carried out to investigate the body weight-regulatory effects of Chekamhanghyuluiyiin-tang plus Zeae Stigma in high fat diet-induced obese rats. Control group rats were fed with high fat diet and administered normal saline for 8weeks. Experimental groups rats were fed with high fat diet and administered extract of 2 kind of Chekamhanghyuluiyiin-tang plus Zeae Stigma each other for 8 weeks. And observed that, body weight of rats and total cholesterol, triglyceride, free fatty acid, total lipid, phospholipid, high density lipoprotein(HDL)-cholesterol, low density lipoprotein(LDL)-cholesterol in serum of rats, and glucose, insulin of rats. The results were as follows; There were significant decrease of serum free ratty acid level in 4CH/sub 5/ group. There were significant decrease of serum glucose level in 4CH/sub 10/ group. According to above mentioned results, Chekamhanghyuluiyiin-tang plus Zeae Stigma was expected to be applied to the prevention or treatment of obesity and its complications.

Associations between Adiponectin and Two Different Cancers: Breast and Colon

  • Gulcelik, Mehmet Ali;Colakoglu, Kadri;Dincer, Halil;Dogan, Lutfi;Yenidogan, Erdinc;Gulcelik, Nese Ersoz
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.395-398
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    • 2012
  • Objectives: Breast and colon cancer are neoplasms well known to be related to obesity. Adiponectin, a protein that increases in obesity, seems to be involved in the relationship but clinical data are limited. Methods: In this study, we therefore evaluated the serum adiponectin levels in 87 breast and 27 colon cancer patients and assessed the relation with BMI, menopausal status, receptor status and stage of disease. Results: Serum adiponectin levels were lower in cancer cases ($8583{\pm}2095$ ng/ml for breast cancer, $9513{\pm}2276$ for colon cancer) than in controls ($13905{\pm}3263$). Conclusion: A low serum adiponectin level may be associated with both breast and colon cancer, and that this association is not statistically significant for either receptor or menopausal status in breast cancer groups.

The Persuasive Effects according to Types of Exercise Promotion Advertisements for Obesity Prevention in Elementary School Students (초등학생의 비만예방을 위한 운동증진 광고의 유형별 설득효과)

  • An Gyeong Ju;Choe Myoung-Ae;Kim Byoung Hee
    • Journal of Korean Academy of Nursing
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    • v.35 no.5
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    • pp.817-828
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    • 2005
  • Purpose: This study was to identify the persuasive effects of exercise promotion advertisements for obesity prevention according to the source types( ordinary people, experts, celebrity endorsers) and advertising message types(slices of life, testimonials). Method: Gender, height, body weight, BMI, attitude toward obesity(Aob) and exercise(Aex), and intention to exercise(Iex) were collected from 626 elementary school students in a pretest. After 2 months, six advertisements type attached to a questionnaire were provided for 20 minutes and then Aob, Aex, lex, source credibility and attitude toward advertisements(Aad) were collected in posttest. Result: 1) In posttest the lex of 6 the groups increased significantly compared with that of the pretest, 2) Source credibility of the Ordinary+Testimonial group was lower than the Celebrity+Testimonial, Celebrity+Slice of life, Ordinary+Slice of life, and Expert+Testimonial groups, Aad of the Celebrity+Testimonial group was higher than the Ordinary+ Testimonial group. 3) The Main effect and interaction effect of source types and advertising message types were significant in source credibility and Aad, Conclusion: Persuasive effects of exercise promotion advertisements in elementary school students was found to be the most effective in Celebrity+Testimonial. This study suggests that selection of health education advertisements according to demographic characteristics is important to promote persuasive effects.

Health-Related Characteristics that Affect the Prevalence of Osteoporosis in Elderly Women

  • Yim, Eun-Sil;Lee, Kwang-Ok;Kim, Kyung-Ha
    • Journal of East-West Nursing Research
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    • v.16 no.2
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    • pp.172-178
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    • 2010
  • Purpose: We examined the relationship between the health-related issues of elderly women and bone density and identified specific factors that affect the prevalence of osteoporosis to provide basic data for developing a health care program on osteoporosis prevention. Methods: This study is a secondary data analysis of 118,903 66-yr-old women who received a health examination conducted by the National Health Insurance Corporation in 2008. Multiple logistic regression analysis was used to identify factors affecting the prevalence of osteoporosis. Results: The prevalence of osteoporosis was 46.8%, whereas the prevalence of osteopenia was 38.4% among elderly women in this study. Statistically significant differences were observed between the osteoporosis and non-osteoporosis group in terms of smoking (p<.001), exercise (p<.001), obesity (p<.001), waist circumference (p<.001), depression (p<.001), falling experience (p<.05), and the cognitive function risk (p<.05). Based on the multiple logistic regression results, the risk for osteoporosis was high in those who were under-weight, smoked, or were depressed. In contrast, moderate or high level obesity showed a negative relationship with osteoporosis. Conclusion: The prevalence of osteopenia and osteoporosis was 85.2%. Therefore, there is a need to develop health care programs pertaining to osteoporosis intervention and prevention for elderly women. Because smoking, non-exercise, and obesity are main osteoporosis risk factors, it is highly recommended that some sound practical life programs and psychological support programs be considered for this population.