• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.7
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• pp.665-670
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• 2016

In this paper, we suggest the design of OP-AMP using MOSFET in the operation of sub-threshold condition as a basic unit of an IoT. The sub-threshold operation of MOSFET is useful for an ultra low power consumption of sensor network system in the IoT, because it cause the supply voltage to be reduced. From the simulation result using 0.35 um CMOS process, the supply voltage, VDD can be reduced with 0.6 V, open-loop gain of 43 dB and the power consumption was evaluated with about $1.3{\mu}W$ and the active size for an integration was measured with $64{\mu}m{\times}105{\mu}m$. It is expected that the proposed circuit is applied to the low power sensor network for IoT.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.4
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• pp.606-614
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• 2000

This study was carried out for comparing Listeria strains developing genetic markers for Listeroa strains using Listeria sp. genetic markers using Randomly Amlymorphic DNA (RAPD) analysis method. Five of RAPD promers (OPA-01, OP-26-01, OP-26-02, OPB-01, OP-26-10) showed the distinctive polymorphism among Kisteria sp. isolated from domestic foods. RAPD-PCR with five arbitrary primers produced 76 DNA polymorphism. Among them, OPA-01 and OP-26-01 primers produced about 1.5kb and 0.7 kb amplified DNA fragments for all the Listeric relationships of Listeria sp. using NTSYS program were grouped into 7 clusters and showed 0.54 to 0.93 similarity among strains. Especially, No. 3 and No. 20 isolates showed the genetically most similar relationship by 0.94, and No. 7 and No. 24, or No. 7 and N0. 45 isolates showed the least similarty by 0.54 From these results, RAPD analysis method deemed to be successfully applied the classification and genetic analysis for Listeria sp. isolates.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.9
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• pp.4334-4356
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• 2017

In orthogonal frequency-division multiplexing (OFDM) systems, phase noise introduced by the local oscillators can cause bit error rate (BER) performance degradation. To solve the phase noise problem, a novel orthogonal-polarization-based phase noise self-cancellation (OP-PNSC) scheme is proposed. First, the efficiency of canceling the phase noise of the OP-PNSC scheme in the AWGN channel is investigated. Then, the OP-PNSC scheme in the polarization-dependent loss (PDL) channel is investigated due to power imbalance caused by PDL, and a PDL pre-compensated OP-PNSC (PPC -OP-PNSC) scheme is proposed to mitigate the power imbalance caused by PDL. In addition, the performance of the PPC-OP-PNSC scheme is investigated, where the signal-to-interference-plus-noise ratio (SINR) and spectral efficiency (SE) performances are analyzed. Finally, a comparison between the OP-PNSC and polarization diversity scheme is discussed. The numerical results show that the BER and SINR performances of the OP-PNSC scheme outperform the case with the phase noise compensation and phase noise self-cancellation scheme.

• Preventive Nutrition and Food Science
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• v.19 no.4
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• pp.291-298
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• 2014

The aim of this study was to investigate the antioxidant activity of orange (Citrus auranthium) flesh (OF) and peel (OP) extracted with acetone, ethanol, and methanol. Antioxidant potential was examined by measuring total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA), total radical-trapping antioxidant potential (TRAP), oxygen radical absorbance capacity (ORAC), and cellular antioxidant activity (CAA). The comet assay was used to determine the protective effects of OF and OP against $H_2O_2$-induced DNA damage. TPC was highest in the acetone extracts of OF and OP. DPPH RSA was also higher in the acetone extracts than in the ethanol extracts. The DPPH RSA was highest in the acetone extracts of OF. The TRAP and ORAC values of the all extracts increased in a dose-dependent manner. In the TRAP assay, the acetone extracts of OF and OP had the lowest $IC_{50}$ values. In the CAA assay, the methanol and acetone extracts of OP had the lowest $IC_{50}$ values. All of the samples protected against $H_2O_2$-induced DNA damage in human leukocytes, as measured by the comet assay, but the acetone extracts of OP had the strongest effect. These results suggest that acetone is the best solvent for the extraction of antioxidant compounds from OF and OP. Furthermore, the high antioxidant activity of OP, which is a by-product of orange processing, suggests that it can be used in nutraceutical and functional foods.

• Journal of People, Plants, and Environment
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• v.21 no.6
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• pp.485-492
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• 2018

This study aimed to develop and validate highly sensitive determination method of a prostaglandin ($PGE_1$, OP 1206) in human plasma by LC-MS/MS using column switching. Plasma stored at $-30^{\circ}C$ and treated with methanol effectively inhibited interferences synthesized post-sampling. Samples were added with internal standard and were separated by reversed-phase HPLC with a cycle time of 30min. The method was selective for OP 1206 and the regression models, based on internal standard, were linear across the concentration range 0.5-50 pg/mL with the limit of quantification of 0.5 pg/mL (limit of quantitation, LOQ) for OP 1206. The calibration curve of OP 1206 standards spiked in five individual plasma samples was linear ($r^2=0.9999$). Accuracy and precision at the concentrations of 0.5, 1.5, 5.0 and 40 pg/mL, and at the lower LOQ of 0.5 pg/mL were excellent at 20%. OP120 < 6 was stable in plasma samples for at least 24 hours at room temperature, 24 hours frozen at $-70^{\circ}C$, 24 hours in an auto sampler at $6^{\circ}C$, and for two freeze/unfreezing cycles. The validated determination method successfully quantified the concentrations of OP 1206 in plasma samples from simulated administrating a single $5{\mu}g$ OP 1206 formulation. Thus, this novel LC-MS/MS technique for drug separation, detection and quantitation is expected to become the standard highly-sensitive detection method in bioanalysis and to be applied to many low dose pharmaceutical products.

• Journal of the Korean Society of Physical Medicine
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• v.17 no.4
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• pp.123-132
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• 2022

PURPOSE: The purpose of this study was to investigate the effects of cognitive orientation to daily occupational performance (CO-OP) interventions on the upper extremity function and occupational performance in subacute stroke patients. METHODS: A total of 30 eligible stroke patients were randomly distributed into the CO-OP experimental group (n = 15) and the traditional occupational therapy (OT) control group (n = 15). The CO-OP approach was applied for twelve 60-minute sessions. The Jebson Taylor Hand Function Test (JTHFT), the Korean version of the Modified Barthel Index (K-MBI), and the Performance Quality Rating Scale (PQRS) were used for outcome evaluations. RESULTS: There was a statistically significant difference in the paralytic upper extremity function before and after treatment (p < .01) between the group treated with the CO-OP approach and the group treated with traditional OT. The occupational performance of the CO-OP approach group showed a significant improvement (p < .01), and this group also showed a statistically significant improvement in quality of performance compared to the traditional OT group (p < .01). CONCLUSION: The CO-OP approach may be useful in clinical practice as a therapeutic intervention for improving the functional recovery and performance of subacute stroke patients. Future research should be carried out to investigate the persistence of this effect involving more participants and follow-up studies should also be undertaken.

• Journal of The Korean Society of Clinical Toxicology
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• v.22 no.1
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• pp.1-9
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• 2024

Purpose: Nutritional therapy is a crucial component of therapy for critically ill patients, but there is a lack of nutritional support guidelines for organophosphate (OP) poisoning, likely due to the gastrointestinal effects of atropine, the main antidote for OP. This study investigated whether enteral nutrition (EN) during atropinization is acceptable for mechanically ventilated patients after OP poisoning. Methods: This retrospective study classified 82 patients with OP poisoning according to whether they were fed during atropinization while on mechanical ventilation (MV). Data on the baseline characteristics, nutritional support, and clinical outcomes were compared. Univariate and multivariate regression models were constructed to analyze the associations between atropine administration for OP poisoning and feeding intolerance-related EN after adjustment for risk factors. Results: Eighty-two patients received EN after 72 hours on MV, and 40 of them simultaneously received 2 mg/hr atropine for the first 120 hours after EN initiation. The overall incidence of feeding intolerance was 57.3% during the first 12 days after EN initiation and did not differ according to atropine administration. Appropriate atropinization during EN in regression model 1 and the dosage of atropine administered during EN and the duration of EN during atropinization in model 2 were not associated with feeding intolerance in patients on MV after OP poisoning. Conclusion: Appropriate atropinization is not associated with feeding intolerance after EN provision in patients on MV after OP poisoning. This study will help establish nutritional guidelines for OP poisoning patients. More research on nutritional support is needed to validate our results.

• Proceedings of the KIEE Conference
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• 1995.07c
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• pp.1108-1110
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• 1995

This paper presents a balanced CMOS complementary folded cascode OP-AMP topology that achieves improved DC gain using the gain boosting technique, a high unity-gain frequency and improved slew rate using the CMOS complementary cascode structure and a high PSRR using the balanced output stage. Bode-plot measurements of a balanced CMOS complementary folded cascode OP-AMP show a DC gain of 80dB, a unity-gain frequency of 110MHz and a slew rate of $274V/{\mu}s$(1pF load). This balanced CMOS complementary folded cascode OP-AMP is well suited for high frequency analog signal processing applications.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2009.11a
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• pp.278-283
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• 2009

Nowadays as public rental apartment increasing, a new national policy for the public rental apartment maintenance is needed. The co-op housing system can be considered as one of the solutions for that needs, as our socio-economical environment changes. This research is on development of the co-op housing maintenance system. The feasibility of the co-op housing maintenance system has been analysed, and an preliminary UML model for the system has been proposed. Research focus is on how the model can be well established from the analysis of a questionnaire survey.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.05a
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• pp.141-144
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• 2002

This study presents the enhancement of forgeability of SNCM522H materials. Target parts are output shaft(OP shaft) used as components of power train for automobiles. To carry out cold forging process of OP shaft by 1 pass instead of existing 2 pass process, studies in terms of process design and heat treatment were performed. To introduce the new process, Finite element Method are accomplished, and to verify the validity of proposed heat treatment cycle, several experiments(Hardness test, Observation of optical microstructures, tensile test) are carried out.