• Archives of Pharmacal Research
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• v.25 no.3
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• pp.336-342
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• 2002

MeOH extract of Kochia scoparia was fractionated into $CHCl_3-$, EtOAc- and BuOH extracts and the last fraction were hydrolyzed by 3%-NaOH ($MeOH-H_2O$) to compare the bioactivities on antinociceptive and anti-inflammatory effects. Silica gel column chromatography of BuOH fraction afforded a large amount of $3-Ο-{\beta}-D-xylopyranosyl {\;}(1{\rightarrow}3)-{\beta}-D-glucuronopyranosyl$ oleanolic acid (momordin Ic, 4) and that of acid hydrolysate of BuOH fraction gave $3-Ο-{\beta}-D-glucuronopyranosyl oleanolic$ acid (momordin Ib, 3), its 6'-Ο-methyl ester (2) and oleanolic acid (1). Silica gel column chromatography of alkaline hydrolysate afforded a large amount of 4. MeOH extract and both EtOAc- and BuOH fractions were active in the rheumatoidal rat induced Freund's complete adjuvant reagent (FCA) whereas $CHCl_3$ fraction was inactive. Compound 1 and 4 showed significant activities in the same assay but oleanolic acid 3-Ο-glucuronopyranoside (3) showed no activity. These fashions were also observed in carrageenan-induced edema of the rat and in the antinociceptive activity tests undertaken in hot plate- and writhing methods. These results suggest that momordin Ic and its aglycone, oleanolic acid, could be active principles for rheumatoid arthritis.

• Journal of Korean Society for Atmospheric Environment
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• v.19 no.E3
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• pp.129-136
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• 2003

Effects of inorganic aerosols on the kinetics of the hydroxyl radical reactions with selected aliphatic alkanes have been investigated using the relative rate technique. The relative rates in the absence and presence of aerosols were determined for n-butane, n-pentane, n-hexane, n-octane, and n-decane. P-xylene was used as a reference compound. Inorganic aerosols including (NH$_4$)$_2$SO$_4$, NH$_4$NO$_3$, and NaCl aerosols at two different aerosol concentrations that are typical of polluted urban conditions were tested. Total surface areas of aerosols were 1400 (Condition I) and 3400 $\mu$$m^2$ cm$^{-3}$ (Condition II). Significant changes in the relative rates in the presence of the inorganic aerosols were not observed for the n-butanel/$.$OH, n-pentanel/$.$OH, n-hexanel/$.$OH, n-octanel/$.$OH, and n-decanel/$.$OH reactions versus p-xylenel/$.$OH reaction. These results suggest that the promoting effects depend on the semiconducting property of the aerosols and the nature of the organic compounds.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 1999.10a
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• pp.99-102
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• 1999

본 연구에서는 대표적인 물리 화학적 토양정화방법인 토양세척기법의 효율증진을 위하여, Fe를 다량 함유한 고농도 윤활유 오염토양을 대상으로 알카리 용액과 산성용액의 세척효율을 비교 검토하고, 과산화수소의 첨가에 따른 세척효율의 향상효과를 알아보았다. 세척용제인 NaOH와 HCl를 이용하여 세척효율 검토 결과 NaOH를 이용한 경우에 약 60% 의 세척효율을 나타냈다. 또한 NaOH 농도에 따른 정화 효율은 각각 0.5% > 1% $\geq$ 2% 순서로 증가하였다. 기존의 세척효율을 향상시키기 위하여 과산화수소를 첨가하고 오염토양의 정화효율을 비교 검토한 결과 NaOH용액에서는 과산화수소의 농도가 증가할수록 정화효율이 증가하였으나 NaOH의 농도증가에 대해서는 큰 영향을 보이지 않았으며, NaOH 3%의 농도에서 과산화수소 1%를 첨가했을 때 85%의 정화효율을 나타냈다. 또한 과산화수소 주입시기에 따른 영향을 검토한 결과 세척 후 과산화수소를 주입한 경우에 정화효율이 높았다. 반면에 HCl의 경우는 HCl의 농도가 증가할수록 정화효율이 증가하였고, 세척하지 않고 과산화수소를 주입한 경우에 정화효율이 증가하였다. 고농도의 윤활유 오염토양의 세척효율을 증진시키기 위한 처리로서 과산화수소의 주입은 NaOH 상태에서 그 효율이 약 15%정도 증진되었으며, 일정시간에 이르면 정화효율이 평형에 도달하는 것을 알 수 있었다. HCl 상태에서는 25%의 정화효율이 증진되는 것을 알 수 있었다.

• Journal of Korean Society of Water and Wastewater
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• v.30 no.4
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• pp.409-415
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• 2016

Magnetite particles were synthesized by co-precipitation of water-soluble 밀 스케일-derived precursor by various concentrations of (0.5, 0.67, 1, 2 N) NaOH and (0.6, 0.8, 1.2, 2.4 N) $NH_4OH$. It is theoretically known that as the concentration of the alkaline additive used in iron oxide synthesis increases, the particle size distribution of that iron oxide decreases. This trend was observed in both kind of alkaline additive used, NaOH and $NH_4OH$. In addition, the magnetite synthesized in NaOH showed a relatively smaller particle size distribution than magnetite synthesized in $NH_4OH$. Crystalline phase of the synthesized magnetite were determined by X-ray diffraction spectroscopy(XRD). The particles were then used as an adsorbent for phosphate(P) removal. Phosphorus adsorption was found to be more efficient in NaOH-based synthesized magnetite than the $NH_4OH$-based magnetite.

• Textile Coloration and Finishing
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• v.6 no.3
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• pp.1-7
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• 1994

Cotton fiber and NaOH-mercerized cotton fiber had been treated by liquid ammonia and were dyed with two direct dyes, C.I. Direct Red 2 and Blue 1. The effect of the treatment on the rate of dyeing, dye adsorption isotherm, and affinity were studied. The rate of dyeing was increased in the order of NaOH-mercerized> NaOH/liquid ammonia-treated > liquid ammonia-treated>Untreated cotton irrespective of kind of dyes. The rate of dyeing for NaOH-treated fiber considerably increased, whereas liquid ammonia-treated or NaOH/liquid ammonia-treated did not because the structural transformation was not enough for the dyes to penetrate easily into the liquied ammonia-treated cottons. The time of half-dyeing was considerably reduced by mercerizing with NaOH, but lengthened by liquid ammonia treatment because of increased equilibrium dye exhaustion especially in dyeing with C.I. Dierect Red 2. In spite of a short time of the ammonia treatment for 4 seconds, the equilibrium exhaustions of both of direct dyes, C.I. Direct Red 2 and C.I. Direct Blue 1, were increased in proportion to internal volume of treated cotton under a condition of fixed affinity.

• Korean Journal of Crystallography
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• v.7 no.2
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• pp.183-190
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• 1996

Single crystals of ZnO were grown hydrothermally with KOH solution in silver lined autoclave. The effect of LiOH and NH4OH on the morphology of as-grown crystals was studied. As-grown crystals were pale green and the maximum size was 30×30×20mm3. Addition of LiOH reduced the density of flaws on the (0001) face of as-grown ZnO crystals. In highly concentrated KOH solution, ZnO had a strong tendency to grow along the c-axis. When 1.0-2.0 M of NH4OH was added into mineralizer, growth rate along the direction of a-axis increased. From this result, ZnO single crystals of equant-faced hexagonal prism could be grown with acicular seeds.

• Korean Journal of Veterinary Research
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• v.51 no.2
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• pp.159-164
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• 2011

Alcohol abuse and its medical and social consequences are a major health problem in many areas of the world. Korean red ginseng (KRG) has been traditionally used for the treatment of liver disease. This study was conducted to evaluate the hepatoprotective effects of KRG against hepatotoxicity in Sprague- Dawley rats treated with ethanol (EtOH). Administration of EtOH for 20 days induced significant changes in serum biochemical parameters (aspartate aminotransferase, alanine transaminase, and glucose) accompanied by histological changes in the liver tissue. Treatment with KRG prior to administration of EtOH inhibited the EtOH-induced biochemical and histological changes of the liver. In perfused rat livers, administration of EtOH caused an increase in lactate dehydrogenase (LDH) release into the perfusate and activated the pro-apoptotic Bax protein but inhibited the anti-apoptotic Bcl-2 protein. Pretreatment with KRG prior to administration of EtOH decreased the EtOH-induced LDH release and inhibition of Bcl-2 protein. These results suggest that KRG exerts anti-apoptotic effects and alleviated EtOH-induced liver injury in rats.

• Journal of the Korean institute of surface engineering
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• v.54 no.1
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• pp.37-42
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• 2021

Electrodeposition is a synthetic method that allows fine control of the nucleation and growth factors of metals and is a suitable method for studying the nucleation and growth of Ni(OH)2. Hexa-methylenetetramine (HMT) helps to form Ni(OH)2 nanosheets by increasing the OH- of the nickel precursor solution and helps to improve the electrochemical properties of the electrode. In this study, the structural properties of Ni(OH)2 nanosheets according to the HMT concentration change using electrodeposition were studied. As the concentration of HMT increased, the size and thickness of the Ni(OH)2 nanosheet adsorbed on the surface increased and porosity increased. Also, the Scharifker-Hills nucleation theory model and experimental data were compared. In conclusion, the nanosheet shape of the HMT 7.5 mM sample electrodeposited with -0.85 V vs. Ag/AgCl grew most uniformly, and the best result was obtained as an electrode material for a pseudocapacitor.

• Korean Journal of Materials Research
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• v.32 no.3
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• pp.153-160
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• 2022

ZnO nanosheets have been used for many devices and antibacterial materials with wide bandgap and high crystallinity. Among the many methods for synthesizing ZnO nanostructures, we report the synthesis of ZnO/Zn(OH)₂ nanosheets using the ionic layer epitaxy method, which is a newly-developed bottom-up technique that allows the shape and thickness of ZnO/Zn(OH)₂ nanosheets to be controlled by temperature and time of synthesis. Results were analyzed by scanning electron microscopy and atomic force microscopy. The physical and chemical information and structural characteristics of ZnO/Zn(OH)2 nanosheets were compared by X-ray photoelectron spectroscopy and X-ray diffraction patterns after various post-treatment processes. The crystallinity of the ZnO/Zn(OH)₂ nanosheets was confirmed using scanning transmission electron microscopy. This study presents details of the control of the size and thickness of synthesized ZnO/Zn(OH)₂ nanosheets with atomic layers.

• Clean Technology
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• v.12 no.2
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• pp.101-106
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• 2006

HT-$LiCoO_2$ powders were synthesized from hydroxide precursors in this study. The cobalt hydroxide compounds with hydrotalcite-like(${\alpha}$-phase) and/or brucite-like(${\beta}$-phase) structures as a component of the precursor were prepared in various PH conditions using precipitation method. It was found that various phase and compositions of cobalt hydroxides could be tailor-prepared via a careful control of preparation parameters such as the concentration ratio of $[OH^-]/[CO^{2+}]$ and aging time. The hydroxides $Co(OH)_2$ and LiOH were mixed with aqueous methyl-alcohol. The precursor of a HT-$LiCoO_2$ was synthesized via subsequent processes including evaporation, drying and aging. The transformation of tailor-made ${\beta}$-phase $Co(OH)_2$ to CoOOH and formation of solid solution in the precursor were achieved during aging. These results cause HT-$LiCoO_2$ to be synthesized at low temperature($600^{\circ}C$ ) for a short time(10min).