• Title/Summary/Keyword: OAL

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Ocular adnexal mucosa-associated lymphoid tissue lymphoma: a narrative review

  • Chung, Hyun Uk;Son, Jun Hyuk
    • Journal of Yeungnam Medical Science
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    • v.39 no.1
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    • pp.3-11
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    • 2022
  • Lymphoma is the most common primary tumor of the orbit, accounting for 55% of all orbital malignancies. When divided into histopathological subtypes, extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises the largest proportion. Clinical manifestations are unspecific, but in patients with slow-growing painless orbital mass, or red conjunctival lesion suggestive of 'salmon patch', ocular adnexa lymphoma (OAL) should be suspected. Although the pathogenetic mechanism of ocular adnexal MALT lymphoma (OAML) is not yet fully understood, the relationship between OAML and Chlamydia psittaci has been hypothesized recently, similar to that between gastric MALT lymphoma and Helicobacter pylori. This suggests a new treatment option for OAML; bacterial eradication therapy with systemic antibiotics. Several other treatment methods for OAML have been introduced, but no treatment guidelines have been established yet. In this article, we summarize the current knowledge on the clinical features, pathogenesis, diagnostic methods, therapeutic strategies, and prognosis of OAML.

Studies on the Grain Size and Acid-consuming Capacity of Aiuminium-Hydroxide Gel (수산화(水酸化)알미늄. 겔의 Grain Size 와 제산도(制酸度)에 관(關)한 연구(硏究))

  • Roe, Tae-Sun
    • Journal of Pharmaceutical Investigation
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    • v.2 no.1
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    • pp.5-13
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    • 1972
  • There are some repels in which they studied on the change of acid-consuming capacity of aluminium hydroxide resulted from the passing of time. However, the relationship between grain sizes(particle sizes) and the acid-consuming capacity of dried aluminium hydroxide gel was not been studied. And studies on the grain sizes of aluminium hydroxide gel qualified by pharmacopoeia of Korea has not been reported. For the purpose of studying these two problems, the author prepared two-kinds of aluminium hydroxide gel as follows : $Na_2OAl_2O_3+CO_2------{\longrightarrow}Al(OH)_3{\cdots}{\cdots}{\cdots}$sample 1 $Al_2(SO_4)_318H_2O+6NaHCO_3{\longrightarrow}Al(OH)_3{\cdots}{\cdots}{\cdots}$sample 2 Both of sample 1 and 2 are found to be amorphous by X-ray diffraction methods, and their acid-consuming capacities were determined by the method of pharmacopeia of Korea. The grain size was measured by X-ray diffraction method, the particle sizes observed by electron microscopy, and the change of acid-consuming capacity with passing of time was determined by the method of pharmacopoeia of Korea. The results of these studies are summerized as follows: 1. The grain size was linearly enlarged as the time goes by. The aluminium hydroxide gel gradually crystallized in a certain period of time. 2. The acid-consuming capacity was in exponential function, decreased as the grain size of them enlarged. 3. One particle consists of tens of grains.4. Grinding the Sample obtained in any period of testing time in mortar did not change both their grain size and their acid-consuming capacity. 5. The grain size of dried aluminium hydroxide gel ought to be micronized less than $100{\AA}$ for maintaining the ability such as consumes 250m1 of 0. 1N-HC1 solution per Is of $Al(OH)_3$ described in pharmacopoeia of Korea.

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The Effects of Coal Thermal Power Plant Exports on the National Economy (석탄화력발전 해외수출의 경제적 파급효과 분석)

  • Jin, Se-Jun;Yoo, Seung-Hoon
    • Journal of Energy Engineering
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    • v.22 no.1
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    • pp.17-27
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    • 2013
  • Korean domestic electricity market is saturated through trying to find ways to overcome the limitations of the domestic electricity industry with overseas electricity markets. Korean electricity industry in the overseas market in order to pursue continuous growth, competitive and aggressive investment in overseas market is promoting. This paper attempts to apply input-output analysis to estimate the role of coal thermal power plant sector exports national economy. More specifically, this study shows what national economy effect of production-inducing effect, value-added inducing effect, and employment-inducing effect are explored with demand-driven model. After define coal thermal power plant sector what small sized of Input-Output table 168 sectors among 17 sectors, this study pays particular and close attention to coal thermal power plant sector by taking the sector as exogenous specification and then investigating economic impacts of it. This study uses coal thermal power plant exportation case of Vietnam project, production-inducing effect, value-added inducing effect, and employment-inducing effect are 2,853 billion won, 973 billion won and 14,761 persons, respectively.

Clinicopathologic Assessment of Ocular Adnexal Lymphoproliferative Lesions at a Tertiary Eye Hospital in Iran

  • Asadi-Amoli, Fahimeh;Nozarian, Zohreh;Bonaki, Hirbod Nasiri;Mehrtash, Vahid;Entezari, Samaneh
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.3727-3731
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    • 2016
  • Background: The most common type of ocular lymphoma is non-Hodgkin lymphoma (NHL), categorized into two groups: indolent (slow growing) and aggressive (rapid growing). Differentiating benign reactive lymphoid hyperplasia (RLH) from malignant ocular adnexal lymphoma (OAL) is challenging. Histopathology, immunohistochemistry (IHC) and flow cytometry have been used as diagnostic tools in such cases. Materials and Methods: In this retrospective case series, from 2002 to 2013 at Farabi Eye Center, 110 patients with ocular lymphoproliferative disease were enrolled. Prevalence, anatomical locations, mean age at diagnosis and the final diagnosis of the disease with IHC were assessed. Comparison between previous pathologic diagnoses and results of IHC was made. Immunoglobulin light chains and B-cell and T-cell markers and other immuno-phenotyping markers including CD20, CD3, CD5, CD23, CD10, CYCLIND1 and BCL2 were evaluated to determine the most accurate diagnosis. The lymphomas were categorized based on revised European-American lymphoma (REAL) classification. Results: Mean age ${\pm}$ SD (years) of the patients was $55.6{\pm}19.3$ and 61% were male. Patients with follicular lymphoma, large B-cell lymphoma or chronic lymphocytic leukemia/small cell lymphoma (CLL/SLL) tended to be older. Nine patients with previous diagnoses of low grade B-cell lymphoma were re-evaluated by IHC and the new diagnoses were as follows: extranodal marginal zone lymphoma(EMZL) (n=1), SLL(n=1), mantle cell lymphoma (MCL) (n=3), reactive lymphoid hyperplasia RLH (n=2). Two cases were excluded due to poor blocks. Flow cytometry reports in these seven patients revealed SLL with positive CD5 and CD23, MCLwith positive CD5 and CyclinD1 and negative CD23, EMZL with negative CD5,CD23 and CD10. One RLH patient was negative for Kappa/Lambda and positive for CD3 and CD20 and the other was positive for all of the light chains, CD3 and CD20. Orbit (49.1%), conjunctiva (16.1%) and lacrimal glands (16.1%) were the most common sites of involvement. Conclusions: Accurate pathological classification of lesions is crucial to determine proper therapeutic approaches. This can be achieved through precise histologic and IHC analyses by expert pathologists.

Development of the 2~8X Zoom Beam Expander for the 1064 nm Laser Source (1064 nm 레이저 관원용 2~8X 줌 빔 확대기 개발)

  • Yi, Meyung-Ha;Lee. Dong-Hee
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.2
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    • pp.23-28
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    • 2008
  • Purpose: To develop the 2~8X zoom beam expander for the 1064 nm laser source. Methods: After developing the program by which the initial design values of 3-component zoom tracks can be quickly obtaind, we design and develop the zoom beam expander by applying this program and the commercial program of Sigma 2000. Results: In this study, we could develop the program by which the initial design values of zoom tracks can be quickly obtaind, and by applying this program and the commercial program of Sigma 2000 we could design and develop the zoom beam expander for 1064 nm which is able to zoom from 2${\times}$ to 8${\times}$. The developed zoom beam expander has an efficient diameter of the incidence side of 8 mm, an efficient diameter of the exit side of 32 mm, and a capacity with the finite ray aberration within 0.0001rad. Because the overall length (OAL) is restricted between 125 mm and 135 mm, the change of the whole barrel length which is caused by variations of the zoom driving becomes to be within 10 mm. Conclusions: we could develop the program by which the initial design values of zoom tracks can be quickly obtaind, and by applying this program we could design and develop the zoom beam expander for 1064 nm which is able to zoom from 2${\times}$ to 8${\times}$.

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