• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.359-363
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• 2021

The purpose of this study is to investigate the effect of gardening programs using therapeutic gardens on the fall efficacy of the elderly. This study was applied to 31 elderly facility users from April to August 2019 at a nursing home P located in Gyeonggi-do. Among the 31 participants who participated in the program, 16 subjects in the experimental group and 15 subjects in the control group were randomly selected. As for the experimental group program, a fall program consisting of fall education and strength training four times a week and a horticultural occupational program were implemented once a week in a healing garden for a total of 15 weeks. The control group performed fall program for 30 minutes 5 times a week for a total of 15 weeks. The fall efficacy of the tested group increased by 5.50 points from 29points before the program to 34.50points after the program, and statistically significant results were obtained (p=0.000). The control group who only progressed the fall program increased 3.63 points from 28.87points before the trial to 32.50points after the trial, and statistically significant results were obtained (p=0.000). From this result, it can be confirmed that the horticultural program using the treatment garden has the potential as a program related to falls. In the future, various studies are needed so that gardening programs using gardens can be applied to prevent falls of the elderly.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.725-735
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• 2022

This study analyzed how the literary works embodying nurses accommodate various discourses about nurses and reproduce them in literature. The subject of analysis is a Korean modern novel featuring a nurse, and 29 works were selected from 1927 to 2016. The analysis method is the content analysis of the novel among the qualitative research methods. The unit of analysis adopts a narrative or dialogue that deals with the image of a nurse in a novel as a unit of analysis, The image determining factors of previous studies were integrated and categorized into 4 types and considered. As a result of analyzing the image of a nurse in the novel, First, traditional image types include Lee Kwang-soo 『Love』, Kim Eui-jung 『Doctor Han』, Jo Jung-rae 『Han River』, Gong Ji-young's 「Field of Stars」, Baek Min-seok 「Poor Little Hans」 Second, social image types include Kang Kyung-ae 「Dark」, Kim Kyung-wook 「Heaven's Gate」, Choi Jeong-hee 「Cheonmaek」 Third, professional image types include Lee Cheong-jun 「Mr. Jo Man-deuk」, 「Discharge」, Choi In-hoon 『The Square』, Kim Yeon-soo 「The Night in the Tunnel Where I Listened to Jusaeng Tudipini」, Jeong Se-lang 『Public health teacher Ahn Eun-young』and Fourth, personal image types include Choi In-ho 「Apprentice Patient」, Kim Jeong-han 「The Third Ward」, Eun Hee-kyung 『Minor League』, Hoon Kim 「Hwajang」, Ha Seong-ran 「The Joy of Eating」, Kim Ji-yeon 「Hippocrates Love Song」, Park Kyung-ri 「Era of Distrust」, Jeong Mi-kyung 「The Lady of Arsenal」 typed as. Through the image of the nurse in the novel, the implications of the novel for human care were discussed.

• The Journal of the Convergence on Culture Technology
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• v.8 no.2
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• pp.187-195
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• 2022

This study was conducted to confirm the relationship between smart device usage time, eye health status, and eye management consciousness during the COVID-19 Pandemic period for college students in the health field. The study participants were 188 health-related university students, and data analysis was performed using descriptive statistics, independent t-test, Chi-square test, one-way ANOVA, and Pearson's correlation coefficients using the SPSS 26.0 program. As a result of the study, the average of the subjects' eye fatigue score was 15.23±13.71, the dry eye subjective symptom score was 21.87±12.02, and the eye health management consciousness score was 3.48±1.09. Eye care awareness, dry eye symptoms (r=.152, p=.005) and eye fatigue, dry eye symptoms (r=.650, p<.001) were statistically significant positive correlation in the group using smartphones for 2 hours or more per day on average. Based on the results of this study, it is necessary to find a way to prevent eye health due to the use of smart devices by college students, and repeated studies are needed to confirm the factors affecting eye health.

• Journal of Hospice and Palliative Care
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• v.24 no.4
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• pp.204-213
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• 2021

Purpose: At the end of life, communication is a key factor for good care. However, in clinical practice, it is difficult to adequately discuss end-of-life care. In order to understand and analyze how decision-making related to life-sustaining treatment (LST) is performed, the shared decision-making (SDM) behaviors of physicians were investigated. Methods: A questionnaire was designed after reviewing the literature on attitudes toward SDM or decision-making related to LST. A final item was added after consulting experts. The survey was completed by internal medicine residents and hematologists/medical oncologists who treat terminal cancer patients. Results: In total, 202 respondents completed the questionnaire, and 88.6% said that the decision to continue or end LST is usually a result of SDM since they believed that sufficient explanation is provided to patients and caregivers, patients and caregivers make their own decisions according to their values, and there is sufficient time for patients and caregivers to make a decision. Expected satisfaction with the decision-making process was the highest for caregivers (57.4%), followed by physicians (49.5%) and patients (41.1%). In total, 38.1% of respondents said that SDM was adequately practiced when making decisions related to LST. The most common reason for inadequate SDM was time pressure (89.6%). Conclusion: Although most physicians answered that they practiced SDM when making decisions regarding LST, satisfactory SDM is rarely practiced in the clinical field. A model for the proper implementation of SDM is needed, and additional studies must be conducted to develop an SDM model in collaboration with other academic organizations.

• Journal of Life Science
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• v.32 no.10
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• pp.821-831
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• 2022

This study evaluated the effects of physical touch play programs in children through a systematic literature review and meta-analysis. A literature search for journal articles published before August 2022 was conducted using KERIS, KISS, DBpia, and ScienceON. The keywords used for the search were 'child', 'infant', 'physical touch', 'physical touch play', 'physical touch activities' and 'physical touch play program'. For the study's purpose, seven studies were selected through a systematic process of using several databases and were used to estimate the effect size of physical touch play programs. A meta-analysis was performed using a random effects model, and the effect size on cognitive function was calculated. Hedges' g of the physical touch play program was 6.20 (95% CI: 3.74-8.66), indicating a large effect size. To determine heterogeneity (I2= 95.4%, Q = 417.30, p<0.001), moderator analysis was performed using the total number of times and intervention duration. The total number of times was statistically significant; the other moderators did not differ significantly. This study systematically analyzed the results of physical touch play programs on children in Korea. It also provides insights that can be applied to the design of physical touch play programs for children. To present more evidence that supports the effectiveness of physical touch programs, further research is warranted.

• Journal of Korea Entertainment Industry Association
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• v.14 no.6
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• pp.289-299
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• 2020

The purpose of this study was to confirm the effect of mindfulness education on perceived stress, mindfulness, psychological well-being, and brain waves. The study used a repeated-measures design to examine 42 female university students currently enrolled in mindfulness courses. Subjects participated in the mindfulness course once a week for eight weeks, 50 minutes per session. The main outcome variables, such as perceived stress, mindfulness, and psychological well-being, were measured with a structured questionnaire and brain waves were measured with an electroencephalograph. The same variables were then measured after the completion of the eight-week course. The results demonstrate that perceived stress significantly decreased from 1.85±0.39 to 1.66±0.39 points (t=3.44, p=.001), while, on the other hand, mindfulness increased from 3.10±0.26 points to 3.19±0.32 points (t =-2.78, p=.008). There was also a significant difference in the level of autonomy, a subcategory of psychological well-being (t=-2.70, p=.010). In addition, EEG indicated significant changes in the frequencies of Theta channel 19 and Rapid Alpha channels 7 and 10. These results suggest that further studies are needed to elucidate the effects of mindfulness education through the modification of mindfulness course plans, diversification of teaching methods, and improvement in the educational environment.

• Nutrition Research and Practice
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• v.16 no.3
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• pp.330-343
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• 2022

BACKGROUND/OBJECTIVES: Zanthoxylum schinifolium is traditionally used as a spice for cooking in East Asian countries. This study was undertaken to evaluate the anti-proliferative potential of ethanol extracts of Z. schinifolium leaves (EEZS) against human bladder cancer T24 cells. MATERIALS/METHODS: Subsequent to measuring the cytotoxicity of EEZS, the anti-cancer activity was measured by assessing apoptosis induction, reactive oxygen species (ROS) generation, and mitochondrial membrane potential (MMP). In addition, we determined the underlying mechanism of EEZS-induced apoptosis through various assays, including Western blot analysis. RESULTS: EEZS treatment concentration-dependently inhibited T24 cell survival, which is associated with apoptosis induction. Exposure to EEZS induced the expression of Fas and Fas-ligand, activated caspases, and subsequently resulted to cleavage of poly (ADP-ribose) polymerase. EEZS also enhanced the expression of cytochrome c in the cytoplasm by suppressing MMP, following increase in the ratio of Bax:Bcl-2 expression and truncation of Bid. However, EEZS-mediated growth inhibition and apoptosis were significantly diminished by a pan-caspase inhibitor. Moreover, EEZS inhibited activation of the phosphoinositide 3-kinase (PI3K)/Akt pathway, and the apoptosis-inducing potential of EEZS was promoted in the presence of PI3K/Akt inhibitor. In addition, EEZS enhanced the production of ROS, whereas N-acetyl cysteine (NAC), a ROS scavenger, markedly suppressed growth inhibition and inactivation of the PI3K/Akt signaling pathway induced by EEZS. Furthermore, NAC significantly attenuated the EEZS-induced apoptosis and reduction of cell viability. CONCLUSIONS: Taken together, our results indicate that exposure to EEZS exhibits anti-cancer activity in T24 bladder cancer cells through ROS-dependent induction of apoptosis and inactivation of the PI3K/Akt signaling pathway.

• Journal of the Korea Convergence Society
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• v.13 no.5
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• pp.425-433
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• 2022

This purpose of this study was to survey state-anxiety, depression and resilience in female high school students and to identify factors influencing resilience. Data were collected 177 female high school students. Data were analyzed using ANOVA, t-test, Scheffe's test, Stepwise Regression Analysis, Pearson's correlation coefficient. The mean score of state-anxiety was 39.56±11.37. There was statistically significant difference in state-anxiety on variable such as academic achievement, satisfaction of school life, parental rearing attitudes, satisfaction of family life. The mean score of depression was 7.53±8.52. There were statistically significant difference in depression on variables such as relationship with school fellow, satisfaction of school life, parental rearing attitudes, satisfaction of family life. The mean score of resilience was 98.36±17.76. There was statistically significant difference in resilience on variables such as academic achievement, parental rearing attitudes, Resilience was negatively correlated with state-anxiety. Resilience was negatively correlated with depression. Self-esteem was positively correlated with depression. Factor influencing resilience were state-anxiety, high academic achievement, which explained 49.6%. Findings provide useful information for further studies in female high school students. Further research with careful sampling will be needed to enhance the resilience of male and female high school students,

• Journal of Life Science
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• v.33 no.5
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• pp.397-405
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• 2023

Although glutathione (GSH) has been shown to play an important role in the prevention of oxidative damage as an antioxidant, studies on immune regulation by it have not been properly conducted. In this study, we investigated whether luthione^®, a reduced GSH, has an immune enhancing effect in murine macrophage RAW 264.7 cells. The results of flow cytometry and immunofluorescence experiments indicated that luthione increased phagocytic activity, a representative function of macrophages, compared to the control cells. According to the results of the cytokine array, the expression of interleukin (IL)-5, IL-1β, and IL-27 was significantly increased in the luthione-treated cells. Luthione also enhanced the production of tumor necrosis factor-α and IL-1β through increased expression of their proteins, and increased release of the immune mediators such as nitric oxide (NO) and prostaglandin E₂ was associated with increased expression of inducible NO synthase and cyclooxygenase-2. In addition, the expression of cluster of differentiation 86, an M1 macrophage marker, was dramatically enhanced in RAW 264.7 cells treated with luthione. Furthermore, as a result of heat map analysis, we found that cytokine signaling 1/3-mediated signal transducer and activator of transcription/Janus tyrosine kinase signaling pathway was involved in the immunomodulatory effect by luthione. In conclusion, our data suggested that luthione could act as a molecular regulator in M1 macrophage polarization and enhance immune capacity by promoting macrophage phagocytic function.

• Journal of Industrial Convergence
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• v.21 no.6
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• pp.37-42
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• 2023

This study aimed to examine the safety of HemoHIM, a dietary supplement containing methoxsalen. HemoHIM is a dietary supplement marketed globally, and a competitor to ginseng. It has been reported to contain methoxsalen, a plant extract for treating psoriasis and vitiligo. Methoxsalen is known to cause hepatotoxicity, but most of the cases has been reported from ingestion as a drug, not a food. There are no reports of hepatotoxicity from the consumption derived from natural products such as Angelica gigas, Cnidium officinale, and Paeonia lactiflora, which are the main ingredients in the HemoHIM. However, a recent case of acute hepatitis was reported in Hong-Kong after ingestion of HemoHIM. It is difficult to conclude that hepatitis was caused by HemoHIM, because there was no check of co-occurring medications with a higher risk of hepatotoxicity, no description of the progress, no quantitative comparison of methoxsalen in HemoHIM to it in common foods such as carrots and celery, and no description of the patient's underlying diseases. On the other hand, there was a study that suggest hemoHIM is safe, and that study had adequate number of subjects even though more studies are needed to ensure safety.