• Parasites, Hosts and Diseases
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• v.55 no.2
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• pp.159-165
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• 2017

Vivax malaria reemerged in Korea in 1993 and the outbreak has been continued with fluctuating numbers of annual indigenous cases. Understanding the nature of the genetic population of Plasmodium vivax circulating in Korea is beneficial for the knowledge of the nationwide parasite heterogeneity and in the implementation of malaria control programs in the country. Previously, we analyzed polymorphic nature of merozoite surface protein-1 (MSP-1) and MSP-$3{\alpha}$ in Korean P. vivax population and identified the Korean P. vivax population has been diversifying rapidly, with the appearance of parasites with new genetic subtypes, despite the recent reduction of the disease incidence. In the present study, we developed simple PCR-RFLP methods for rapid subtyping of MSP-1 and MSP-$3{\alpha}$ of Korean P. vivax isolates. These PCR-RFLP methods were able to easily distinguish each subtype of Korean P. vivax MSP-1 and MSP-$3{\alpha}$ with high accuracy. The PCR-RFLP subtyping methods developed here would be easily applied to massive epidemiological studies for molecular surveillance to understand genetic population of P. vivax and to supervise the genetic variation of the parasite circulating in Korea.

• Biomedical Science Letters
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• v.10 no.2
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• pp.163-169
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• 2004

Worldwide, tuberculosis remains one of the leading infectious diseases, accounting for nearly 3 million deaths and more than 8 million new cases annually. DNA typing of Mycobacterium tuberculosis is important for the control of tuberculosis, since it can be used to track transmission route of tuberculosis, source of internal laboratory contaminations, and to answer questions on the nature of tuberculosis infections such as reactivation or exogenous reinfection of disease. At present, IS6110-based RFLP is the choice of method for typing large numbers of clinical isolates of M. tuberculosis, since it has the highest resolution power. However, RFLP requires long time, high cost and qualified experts, so only reference level laboratories can use the RFLP technique. In order to have an optional molecular typing method suitable for the clinical settings, this study evaluated the use of one of PCR-based typing methods, IS6110-based outward PCR for typing clinical isolates of M. tuberculosis. In brief, the results from this study showed that IS6110-based RFLP is useful to discriminate diverse clinical isolates of M. tuberculosis as well as to identify clinical isolates that belong to the same family or cluster groups that have been previously classified by RFLP analysis. In addition, the banding profiles resulted from IS6110-based outward PCR seemed to represent genomic characteristics of M. tuberculosis, since strains belong to the K-family generated unique band that is not present in any other strains but present only in the genome of K-family strains. The IS6110-based outward PCR was also shown to be useful with DNAs isolated directly from liquid cultures indicating this method can be suitable for typing M. tuberculosis in clinical settings.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2459-2465
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• 2012

Background: Numbers of epidemiological studies assessing residential radon exposure and risk of lung cancer have yielded inconsistent results. Methods: We therefore performed a meta-analysis of relevant published case-control studies searched in the PubMed database through July 2011 to examine the association. The combined odds ratio (OR) were calculated using fixed- or random-effects models. Subgroup and dose-response analyses were also performed. Results: We identified 22 case-control studies of residential radon and lung cancer risk involving 13,380 cases and 21,102 controls. The combined OR of lung cancer for the highest with the lowest exposure was 1.29 (95% CI 1.10-1.51). Dose-response analysis showed that every 100 Bq/$m^3$ increment in residential radon exposure was associated with a significant 7% increase in lung cancer risk. Subgroup analysis displayed a more pronounced association in the studies conducted in Europe. Studies restricted to female or non-smokers demonstrated weakened associations between exposure and lung cancer. Conclusions: This meta-analysis provides new evidence supporting the conclusion that residential exposure to radon can significantly increase the risk of lung cancer in a dose-response manner.

• Animal Bioscience
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• v.37 no.2
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• pp.184-192
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• 2024

Objective: This study aims to investigate the genetic structure and characteristics of the Angus cattle population in Hungary. The survey was performed with the assistance of the Hungarian Hereford, Angus, Galloway Association (HHAGA). Methods: Genetic parameters of 1,369 animals from 16 Angus herds were analyzed using the genotyping results of 12 microsatellite markers with the aid of PowerMarker, Genalex, GDA-NT2021, and STRUCTURE software. Genotyping of DNA was performed using an automated genetic analyzer. Based on pairwise identity by state values of animals, the Python networkx 2.3 library was used for network analysis of the breed and to identify the central animals. Results: The observed numbers of alleles on the 12 loci under investigation ranged from 11 to 18. The average effective number of alleles was 3.201. The overall expected heterozygosity was 0.659 and the observed heterozygosity was 0.710. Four groups were detected among the 16 Angus herds. The breeders' information validated the grouping results and facilitated the comparison of birth weight, age at first calving, number of calves born and productive lifespan data between the four groups, revealing significant differences. We identified the central animals/herd of the Angus population in Hungary. The match of our group descriptions with the phenotypic data provided by the breeders further underscores the value of cooperation between breeders and researchers. Conclusion: The observation that significant differences in the measured traits occurred among the identified groups paves the way to further enhancement of breeding efficiency. Our findings have the potential to aid the development of new breeding strategies and help breeders keep the Angus populations in Hungary under genetic supervision. Based on our results the efficient use of an upcoming genomic selection can, in some cases, significantly improve birth weight, age at first calving, number of calves born and the productive lifespan of animals.

• Journal of Korean Neurosurgical Society
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• v.64 no.6
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• pp.922-932
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• 2021

Objective : It is challenging to make solid fusion by posterior screw fixation and laminectomy with posterolateral fusion (PLF) in thoracic and thoracolumbar (TL) diseases. In this study, we report our experience and follow-up results with a new surgical technique entitled posterior thoracic cage interbody fusion (PTCIF) for thoracic and TL spine in comparison with conventional PLF. Methods : After institutional review board approval, a total of 57 patients who underwent PTCIF (n=30) and conventional PLF (n=27) for decompression and fusion in thoracic and TL spine between 2004 and 2019 were analyzed. Clinical outcomes and radiological parameters, including bone fusion, regional Cobb angle, and proximal junctional Cobb angle, were evaluated. Results : In PTCIF and conventional PLF, the mean age was 61.2 and 58.2 years (p=0.46), and the numbers of levels fused were 2.8 and 3.1 (p=0.46), respectively. Every patient showed functional improvement except one case of PTCIF. Postoperative hematoma as a perioperative complication occurred in one and three cases, respectively. The mean difference in the regional Cobb angle immediately after surgery compared with that of the last follow-up was 1.4° in PTCIF and 7.6° in conventional PLF (p=0.003), respectively. The mean durations of postoperative follow-up were 35.6 months in PTCIF and 37.3 months in conventional PLF (p=0.86). Conclusion : PTCIF is an effective fusion method in decompression and fixation surgery with good clinical outcomes for various spinal diseases in the thoracic and TL spine. It provides more stable bone fusion than conventional PLF by anterior column support.

• Korean Journal of Veterinary Research
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• v.62 no.3
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• pp.24.1-24.7
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• 2022

Incidences of major feline viral diseases provide basic information for preventing viral disease in cats. Despite the growing interest in feline viral diseases, sero-surveillances have been lacking. In this study, we analyzed the diagnoses of feline viral diseases and conducted a sero surveillance of feline panleukopenia virus (FPV), feline calicivirus (FCV), feline herpesvirus-1 (FHV-1), and feline infectious peritonitis virus (FIPV) in Korean cats. Of the 204 confirmed cases since 2015, the numbers of diagnoses for FPV, FIPV, FCV, feline influenza virus, and FHV-1 were 156, 32, 12, 3, and 1 case, respectively. In total, 200 sera, collected between 2019 and 2021, were screened for the presence of antibodies against FPV, 2 FCVs, FHV-1, and FIPV using a hemagglutination inhibition test and a virus-neutralizing assay (VNA). The overall seropositive rates in cats tested for FPV, the 2 FCVs, FHV-1, and FIPV were 92.5%. 42.0%, 37.0%, 52.0%, and 14.0%, respectively. A low correlation (r = 0.466) was detected between the VNA titers of 2 FCV strains. The highest incidence and seropositive rate of FPV reveal that FPV is circulating in Korean cats. The low r-value between 2 FCVs suggests that a new feline vaccine containing the 2 kinds of FCVs is required.

• International Journal of Computer Science & Network Security
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• v.23 no.2
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• pp.111-125
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• 2023

Due to the car's central role in modern life, the industry has become more fiercely competitive, with each manufacturer doing everything it can to attract buyers with features like plush interiors, comprehensive warranties, and helpful customer service departments. Customers may not have the luxury of buying a new car, so they will have to buy a used car. Nevertheless, in most cases, the customer (car driver) may be deceived about the vehicle information and history and thus will be confused in making his/her decision to purchase. In addition, after all attempts to obtain vehicle information (plate number, model, year of manufacture, number of maintenance times, accidents, etc.), the customer's many attempts may fail. In general, the government records and verifies the information of all cars, even those that pass through their borders. However, there might still be some trouble in obtaining this information. From this standpoint, we will design a website that makes it easier for car drivers, car companies and governments to carry out all the above-mentioned processes. It will also allow users, whether a driver or a car company, to inquire about all vehicle information through detailed and integrated reports on its condition since its entry into the Kingdom of Saudi Arabia until the present time, in addition to information supported by numbers and statistics to ensure the integrity and reliability of the information. This platform will save the trouble of searching for car information for drivers and car companies. It will also help governments keep track of the information of all cars entering and leaving the Kingdom of Saudi Arabia, which will contribute to facilitating the process of viewing the history of any car that has previously entered the Kingdom's borders.

• Culinary science and hospitality research
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• v.17 no.1
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• pp.44-57
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• 2011

The purpose of this study is to suggest methods to globalize Korean food and actual conditions of Korean restaurants in Brisbane and Sunny Bank, Australia. The period of the survey was from July 19 to Aug 13, 2010. As a analysis method, in-depth interviews were conducted and the result was suggested by general arrangement in cases that responses to the interview questions were considered overlapping or similar. The result of the study on methods to globalize Korean food is as follows. First, development and improvement of favorable cuisine for Australians is essential. Second, the government should lead the promotion of food supply and dishes. Third, personnel in the food industry not only need to be trained to communicate well but also have exposure to different cultures around the world. For the limit of the study, it was difficult to secure enough samples of the subjects for an in-depth interview due to lack of numbers of Korean restaurants. In future studies, research on new methods for the globalization of Korean food should be conducted by doing research on Korean restaurants in other areas of Australia.

• Nuclear Engineering and Technology
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• v.52 no.9
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• pp.1917-1925
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• 2020

New versions of ENDF/B and JEFF data libraries have been released during the past two years with significant updates in the neutron reaction sublibrary and the thermal neutron scattering sublibrary. In order to get a more comprehensive impression of the criticality quality of these two latest neutron data libraries, and to provide reference for the selection of the evaluated nuclear data libraries for the science and engineering applications of the Reactor Monte Carlo code RMC, the criticality benchmarking of the two latest neutron data libraries has been performed. RMC was employed as the computational tools, whose processing capability for the continuous representation ENDF/B-VIII.0 thermal neutron scattering laws was developed. The RMC criticality validation suite consisting of 116 benchmarks was established for the benchmarking work. The latest ACE format data libraries of the neutron reaction and the thermal neutron scattering laws for ENDF/B-VIII.0, ENDF/B-VII.1, and JEFF-3.3 were downloaded from the corresponding official sites. The ENDF/B-VII.0 data library was also employed to provide code-to-code validation for RMC. All the calculations for the four different data libraries were performed by using a parallel version of RMC, and all the calculated standard deviations are lower than 30pcm. Comprehensive analyses including the C/E values with uncertainties, the δk/σ values, and the metrics of χ² and < |Δ| >, were conducted and presented. The calculated keff eigenvalues based on the four data libraries generally agree well with the benchmark evaluations for most cases. Among the 116 criticality benchmarks, the numbers of the calculated keff eigenvalues which agree with the benchmark evaluations within 3σ interval (with a confidence level of 99.6%) are 107, 109, 112, and 113 for ENDF/B-VII.0, ENDF/B-VII.1, ENDF/B-VIII.0 and JEFF-3.3, respectively. The present results indicate that the ENDF/B-VIII.0 neutron data library has a better performance on average.

• Journal of the Institute of Convergence Signal Processing
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• v.11 no.2
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• pp.97-103
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• 2010

In this paper, we propose a new digital watermarking technique. The main idea of the proposed algorithm relies on the assumption that any real number can be expressed as a summation of the exponential form with base of 2 and if only consider the first few summations some numbers can be expressed in the same form. Therefore, we can be sure that some amount of changes does not affect the first few summations. The algorithm decomposes a host image in wavelet domain and intensity of the significant wavelet coefficient is expressed in exponential form with base of 2. Multiple barcode watermarks are then embedded by modifying the parity of the exponent. The proposed scheme is semi-blind and also offers either objective or subjective deteew su as well. From extracted watermarks, more accurate watermark is obtained by merging technique as a final watermark. As a simulation result, the proposed algorithm could resist most cases of salt and pepper noise, Gaussian noise and JPEG compression.