• 산업융합연구
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• 제20권10호
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• pp.87-94
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• 2022

본 논문은 ESG에 따른 신 산업기술 재편으로 V4 지역은 한국의 배터리 제조기지의 변곡점을 제기하고자 한다. 이는 코로나19에 따른 경제 위기속에 러시아-우크라이나 전쟁과 미-중간의 패권을 겨루고 있기 때문이다. 그로 인해 글로벌 공급망 시장은 단절된다. 중국과 러시아로부터의 유럽으로 광물, 곡물조달이나, 가스, 심지어 밀 수입이 여의치 않는 환경에서, 신 공급처의 다각화가 나타나고 있다. 보호주의와 글로컬로써, 이 지역은 러시아-우크라전쟁으로 완충지대(친러, 헝가리)에서 고립지대(반러, 폴란드)로 활용된다. EU 테이퍼링 기간과 높은 인플레이션으로 세계경제 성장은 더 둔화될 전망이다. 논문의 경우 이 지역의 시장단절(chasm) 방안을 다룬다. 이러한 변화에 신사업 기술의 전환과 에너지 공급에 따른 독일의 산업위축이 지난 20년간 경제성장 원동력을 잃게 될 수도 있다. 이는 명목 지표에서 현지 시장 단절(chasm)이 발생하고 있다. 다른 한편으로 한국은 희토류소재 공급망의 불균형에 따른 우회 개발공급 지역으로써, V4지역에 AI를 접목한 에너지 발전 수출(원전 및 전기-수소 발전)지역으로 전개해야 한다. 본 논문은 이러한 산업 연계로 인한 시장단절을 극복하려면, 신에너지 개발과 플랫폼 규모화를 이루고, 세계 각국에서 신뢰적인 공급 기술(차세대 전지, 재활용기술, 저가LFP)을 다각화를 형성할 수 있음을 방증하고 있다.

• Journal of Photoscience
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• 제9권2호
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• pp.451-453
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• 2002

A new concept of "photo" -antisense method has been evaluated, where the inhibition of gene expression by the conventional antisense method is enhanced by photochemical binding between antisense oligonucleotides conjugated with photo-reactive compound and target mRNA or DNA. Fluorescein labeled oligodeoxyribonucleotides (F-DNA) was delivered to cell nuclei in the encapsulated form in multilamellar lecithin liposomes with neutral charge. F-DNA was previously shown to photo-bind to the complementary stranded DNA, and the delivery system using neutral liposome to be effective in normal human keratinocytes. In the present study, we used human kidney cancer G401.2/6TG.1 cell line to be advantageous in reproducible experiments. p53 was adopted as a target gene since antisense sequence information has been accumulated. The nuclear localization ofF-DNA was identified by comparing the fluorescence ofF-DNA with that of Hoechst 33258 under fluorescence microscope. After 7hr incubation to accumulate p53 protein induced by UV -B, p53 protein was quantified by Western blot. After 2hrs from F-DNA application, about 30% of cell population incorporated F-DNA in their nuclei with some morphological change possibly due to liposomal toxicity. Irradiation of visible light longer than 400nm from solar simulator at this time enhanced the inhibitory action of antisense F-DNA. The present results suggest that photo-antisense method is promising to control gene expression in time and space dependent manner. Further improvement of F-DNA delivery to cancer cells in the stability and toxicity is in progress. progress.

• Carbon letters
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• 제22권
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• pp.1-13
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• 2017

Porous materials play a vital role in science and technology. The ability to control their pore structures at the atomic, molecular, and nanometer scales enable interactions with atoms, ions and molecules to occur throughout the bulk of the material, for practical applications. Three-dimensional (3D) porous carbon-based materials (e.g., graphene aerogels/hydrogels, sponges and foams) made of graphene or graphene oxide-based networks have attracted considerable attention because they offer low density, high porosity, large surface area, excellent electrical conductivity and stable mechanical properties. Water pollution and associated environmental issues have become a hot topic in recent years. Rapid industrialization has led to a massive increase in the amount of wastewater that industries discharge into the environment. Water pollution is caused by oil spills, heavy metals, dyes, and organic compounds released by industry, as well as via unpredictable accidents. In addition, water pollution is also caused by radionuclides released by nuclear disasters or leakage. This review presents an overview of the state-of-the-art synthesis methodologies of 3D porous graphene materials and highlights their synthesis for environmental applications. The various synthetic methods used to prepare these 3D materials are discussed, particularly template-free self-assembly methods, and template-directed methods. Some key results are summarized, where 3D graphene materials have been used for the adsorption of dyes, heavy metals, and radioactive materials from polluted environments.

• 한국방사선학회논문지
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• 제11권5호
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• pp.321-328
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• 2017

D-Shuttle (Chiyoda Technol Corporation, Tokyo, Japan) 선량계를 이용하여 개인피폭관리 및 자연방사선량의 모니터링을 위한 기초자료를 제공하는데 연구의 목적이 있다. D-Shuttle을 이용하여 선량을 산출하였다. 선량보고서에서 400 일 노출되었을 때에 1.346 mSv 이었고, 연간선량 (annual dose per year)은 1.228 mSv/year, 평균시간선량 (average dose per hour)은 $0.014{\mu}Sv/hr$ 이었다. 국내의 개인 외부피폭선량 (1.295 mSv/year =Korea average natural individual external dose), 국내의 연간부가선량 (additional dose per year)은 -0.0663 mSv/year 이다. D-Shuttle은 방사선모니터링을 위한 개인선량계로 방사선의 검출성능 우수한 기능, 실시간 방사선 피폭관리, 방사선 작업의 경보 기능, 효율적이고 사용이 편리한 개인 방사선선량의 피폭관리로 ALARA에 매우 유용한 선량계로 사용할 수 있다. 방사선작업종사자와 지역주민의 방사선모니터링 측정기기로 병원, 산업, 의료현장, 원전사고 지역과 비파괴 분야의 위험한 지역에서 방사선모니터링으로 활용될 수 있다.

• 대한가정학회지
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• 제11권4호
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• pp.414-423
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• 1973

Before the modern education was introduced in Korea men had the opportunity to be educated. Women's education was limited to a small number of girls belonging to ruling class. It was the men who got a job to earn the money for the family. The customary law prohibited women from being employed. They were to stay at home engaged in household affairs. This phenomenon has undergone a change when modern education was adopted which gave women the equal opportunity in education. The modernization of the country required a lot of educated and skilled labour. Since 1945 when Korea was liberated from the Japanese colonial administration the modernization programme has been worked out in every field such as industry, education, culture and politics, etc. The traditional grand family was transformed to nuclear family. The migration took place from country to town. With the adoption of compulsory education in the primary school the schoolgirls are increased in great number. The number of girls has been increased every year in Middle Schools, High schools and Universities. Even if boys still outnumber girls in all education institutions, the rate of increase of girl students are higher than that of boy students. Accordingly women are given more opportunity than ever for the employment vis-a-vis men. The number of employed women has been increasing greatly in recent years inproportion to the acceleration of industrialization. The type of their job is also various and colorful ranging from factory worker to doctor and lawyer. There are some problems to be solved with respect to the improvement of women's education. The improved women's education should be reviewed light of the fact that inequality still exists between men and women in occupation and wages, and that women is required of good education contributable to the better Korean society.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2004년도 학술논문집
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• pp.345-345
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• 2004

사용후핵연료 수송용기는 원자력발전소의 운영에 있어서 매우 중요한 구성요소의 하나로서 역할을 해왔으며, 근래에 들어서는 발전소 부지 또는 저장시설에서의 저장용기로 함께 사용되면서 그 숫자가 급속히 증가하고 있다. 아직 엄청난 양의 사용후핵연료가 발전소 내의 사용후핵연료 저장조와 같은 수조에 저장되어 있지만, 최근에는 사용후핵연료의 단기 또는 장기 저장을 위한 효과적인 수단으로 수송용기를 이용한 저장을 채택하는 국가가 계속 증가하고 있다. 사용후핵연료 수송용기의 운전 및 유지보수에 대한 오랜 기간의 경험에서 얻은 기술적 노하우는 저장용기의 운전 및 유지보수에도 잘 활용될 수 있을 것이다. 수송저장 겸용용기 및 다목적용 용기의 증가는 이러한 겸용용기의 운전 및 유지보수에 대한 국제적 표준화를 요구하고 있다. 이에 대한 노력의 일환으로 국제원자력기구에서는 이들 겸용 용기에 대한 설계요구사항들을 지침의 형태로 마련하고 있다.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.300-305
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• 2007

In this study, we have studied the fabrication and the performance evaluation of digital radiation detector of the based on selenium (a-Se) prototype which is widely researched about recently. The detector was fabricated using amorphous selenium in the specification of active area size $7{\times}8.5"$, pixel pitch $139{\mu}m$, and 12 bit ADC. In order for the performance evaluation of the fabricated detector, we used radiation quality RQA 5 that is suggested by the International Electrotechnical Commission (IEC), and evaluated modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE). Concerning MTF measurement, we used slit camera (Nuclear Associates, Model : 07-624-2222), and evaluated in the slit method. Also so as to compare the performance evaluation on the detector fabricated in this study, we used Hologic Direct-Ray (DR-1000) and GE Revolution XQ/I system, and evaluated and compared in the same method MTF, NPS, and DQE which are image quality factors. And as a result, the MTF of each detector In Nyquist frequency were evaluated to be 58% (at 3.5 lp/mm) in the case of DR-1000 and 65% (at 2.5 lp/mm) in the case of XQ/I, and that for the detector fabricated in this study was evaluated to be 36% (at 3.51 lp/mm). Also in the case of DQE(0), the detector fabricated in this study, DR-1000 of Hologic company, and XQ/I system of GE company respectively were evaluated as 36%, 32%, and 50%.

• ALGAE
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• 제29권3호
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• pp.237-247
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• 2014

Polysaccharides prepared from marine algae sometimes contain contaminants such as polyphenols and endotoxins that may mislead their bona fide biological activities. In this study, we examined bioactive contaminants in commercially available fucoindan from Fucus vesiculosus, along with ascophyllan and fucoidan from Ascophyllum nodosum. F. vesiculosus fucoidan inhibited the growth of Vibrio alginolyticus in a concentration-dependent manner ($0-1,000{\mu}g\;mL^{-1}$). However, the antibacterial activity of the fucoidan significantly reduced after methanol-extraction, and the methanol-extract showed a potent antibacterial activity. The extract also showed cytotoxicity to RAW264.7 and U937 cells, and induced apoptotic nuclear morphological changes in U937 cells. These results suggest that the antibacterial activity of the fucoidan is partly due to the methanol-extractable contaminants that can also contribute to the cytotoxicity on RAW264.7 and U937 cells. On the other hand, the activities to induce secretion of nitric oxide and tumor necrosis factor-${\alpha}$ from RAW264.7 cells were observed in the fucoidan even after methanol extraction, and the extract had no such activities. Our observations suggest that commercially available fucoidan should be purified prior to biochemical use.

• Mycobiology
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• 제48권3호
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• pp.184-194
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• 2020

Macrofungi play important roles in forest ecology as wood decayers, symbionts, and pathogens of living trees. For the effective forest management, it is imperative to have a comprehensive overview of macrofungi diversity in specific areas. As a part of the National Institute of Biological Resources projects for discovering indigenous fungi in Korea, we collected macrofungi in Gayasan National Park from 2017 to 2018. These specimens were identified based on morphological characteristics and sequence analysis of internal transcribed spacer (ITS) or the nuclear large subunit rRNA (LSU) region. We discovered 17 macrofungi new to Korea: Butyrea japonica, Ceriporia nanlingensis, Coltricia weii, Coltriciella subglobosa, Crepidotus crocophyllus, Cylindrobasidium laeve, Fulvoderma scaurum, Laetiporus cremeiporus, Lentinellus castoreus, Leucogyrophana mollusca, Marasmius insolitus, Nidularia deformis, Phaeophlebiopsis peniophoroides, Phanerochaete angustocystidiata, Phlebiopsis pilatii, Postia coeruleivirens, and Tengioboletus fujianensis. We described their detailed morphological characteristics.

• Bulletin of the Korean Chemical Society
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• 제32권6호
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• pp.2021-2026
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• 2011

AgNPs (silver nanoparticles) has been widely used for the commercial products, which have antimicrobial agent, medical devices, food industry and cosmetics. Despite, AgNPs have been reported as toxic to the mammalian cell, lung, liver, brain and other organs and many researchers have investigated the toxicity of AgNPs. In this study, we investigated toxicity of the AgNPs to the liver cell using metabolomics based on HRMAS NMR (High Resolution Magic Angle Spinning Nuclear Magnetic Resonance) technics, which could apply to the intact tissues or cells, to avoid the sample destruction. Target profiling and multivariative statistical analysis were performed to analyze the 1D $^1H$ spectrum. The results show that the concentrations of many metabolites were affected by the AgNPs in the liver cell. The concentrations of glutathione (GSH), lactate, taurine, and glycine were decreased and most of amino acids, choline analogues, and pyruvate were increased by the AgNPs. Moreover, the levels of the metabolites were recovered upto similar level of metabolites in the normal cell by the pre-treatment of NAC, external antioxidant. The results suggest that the depletion of the GSH by the AgNPs might induce the conversion of lactate and taurine to the pyruvate.