• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.1 s.244
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• pp.90-96
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• 2006

Since Risk Based Inspection(RBI) was introduced to quality the risks for jet engine and nuclear power, the technique has been expanded to the area of petrochemical plant. Recently among USA and Europe, window-based computer programme for RBI has been rapidly developed. When local companies procure such program to apply to their plants, it is difficult to build up a proper database as well as expect a good result. In this regards, K-RBI programme accustomed to Korean environments was developed. After completion of the programme in 2004, it was tested by 2 local petrochemical plants and was produced fruitful results. By using these programme, we are expecting accident prevention through risk based planning and implementing of equipment inspection, and saving dollars caused by procuring foreign expensive programme.

• Journal of Microbiology and Biotechnology
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• v.22 no.9
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• pp.1214-1217
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• 2012

One Helicosporium strain, isolated from a wilted chestnut tree, evidenced in vitro antimicrobial activity against various types of bacteria and fungi, and generated a diffusible pigment. The antimicrobial compounds and the diffusible pigment of the Helicosporium sp. isolate were purified via solvent fractionation, column chromatography, and recycling preparative chromatography. Both the major antimicrobial compound and the diffusible pigment were identified as 2-methylresorcinol via nuclear magnetic resonance spectroscopy. Therefore, 2-methylresorcinol, a diffusible pigment generated by Helicosporium sp., appears to be an active antimicrobial principle. This pigment also exhibited considerable cytotoxicity against mammalian cells.

• Proceedings of the KIEE Conference
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• 2001.07b
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• pp.675-677
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• 2001

The neutron controls a nuclear fission in the core of reactor. In-core neutron detector drive system is a equipment that drives detector and cable to survey neutron flux in the reactor. The program introduced by this paper governs proto-type drive system. The basic function of drive system is the insert and the withdraw of a cable, and the control of the movement speed. Also this program have a special function, test, auto operation, to increase the capacity of drive system.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1996.10a
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• pp.70-77
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• 1996

In this study, sliding response analysis of free standing structure such as multi-purpose nuclear spent fuel storage cask is peformed. The governing factors of sliding response are aspect ratio of structure and ground acceleration. The vertical acceleration component is very important factor in the sliding response of the structure. Based on the mathematical model, computer program is developed using direct forward integration method to predict the sliding response. Using the program, several parametric studies were made for sinusodial ground motion and for El Centre 1940 earthquake and Mexico 1973 earthquake. From the results, it is known that the frequency content and duration of strong motion affect the sliding of the structure.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2011.10a
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• pp.221-226
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• 2011

The structural integrity of APR1400 reactor vessel internals has been being assessed referring the US Nuclear Regulatory Commission regulatory guide 1.20 comprehensive vibration assessment program. The program is composed of a vibration and stress analysis, a limited vibration measurement, and an inspection. This paper covers the vibration and stress analysis on the reactor vessel internals due to the pulsation of reactor coolant pump. 3-dimensional models to calculate the hydraulic loads and structural responses were built and the pressure distributions and the structural responses were predicted using ANSYS. The peak stress of the reactor vessel internals is much lower than the acceptance limit.

• Journal of Industrial Technology
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• v.25 no.A
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• pp.31-38
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• 2005

Recent earthquakes have shown that near-field earthquakes can produce spectral demands significantly larger than those considered in current design code. International Atomic Energy Agency (IAEA) has recently initiated a coordinated research program on safety significance of near-field earthquakes. The purpose of this program is to focus on the assessment of vulnerability of nuclear facility structures by using and adapting the best available engineering practices appropriate to evaluate the effects of near-field earthquakes. The objective of this paper is to evaluate of seismic responses of a shear building test specimen subjected to near-filed earthquakes. To achieve the objective, the seismic responses of the test specimen, evaluated by the Displacement Coefficient Method (DCM) and Nonlinear Dynamic Analysis (NDA), are compared with those by the experimental tests.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.106-109
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• 2012

Purpose : The KOTRON-13 cyclotron was developed and installed in regional cyclotron centers to produce short-lifetime medical radioisotopes. However, this cyclotron has limited capacity to produce $^{11}C$ so far. In present study, we developed an effective $^{11}C$ target system combining with fluorine-18 target and applied to the production of various $^{11}C$ radiopharmaceuticals. Materials and Methods : To develop the optimal $^{11}C$ target system and effective its cooling system, we designed the $^{11}C$ target system by Stopping and Range of Ions in Matter (SRIM) simulation program and considered the cavity pressure during irradiation at target grid. In this investigation, we modified target materials, cavity shapes and the position of cooling system in $^{11}C$ target and then evaluated $[^{11}C]CO_2$ production at different beam currents, thickness of the target foil, oxygen content of nitrogen gas and target gas loading pressure. Also, we evaluate the production of several $^{11}C$ radiopharmaceuticals such as [$^{11}C$]PIB, [$^{11}C$]DASB, and [$^{11}C$]Clozapine. Results : $[^{11}C]CO_2$ was produced about 74 GBq for 30min irradiation at 60 ${\mu}A$ of beam current as following conditions: thickness of the target foil: 19 nm HAVAR, oxygen content of nitrogen: under 50 ppb, target gas loading pressure: 24 bar. Additionally, the cooling system was stable to produce $[^{11}C]CO_2$ at high beam current. The radiochemical yields of [$^{11}C$]PIB, [$^{11}C$]DASB, and [$^{11}C$]Clozapine showed about 26-38% with over 127 GBq/umol of specific activity. Conclusion : The carbon-11 target system in the KOTRON-13 cyclotron was successfully developed and showed stable production of $[^{11}C]CO_2$. These results showed that our $^{11}C$ target system will be compatible with other commercial system for the routine $^{11}C$ radiopharmaceuticals production in the KOTRON-13 cyclotron.

• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.1
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• pp.86-89
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• 2011

Purpose: The KOTRON-13 cyclotron was developed in South Korea and was introduced to regional cyclotron centers to produce short-lifetime medical radioisotopes. However, this cyclotron has limited capacity to produce carbon-11 isotope so far. We herein study how to develop and optimize an effective carbon-11 target system in the KOTRON-13 cyclotron by changing cooling system, combing with fluorine-18 target and evaluating beam currents. Materials and Method: To develop the optimal carbon-11 target and an effective cooling system, we designed the carbon-11 target system by Stopping and Range of Ions in Matter (SRIM) simulation program and considered the cavity pressure during irradiation at target grid. In this investigation, we evaluated the yield of carbon-11 production at different beam currents and the stability of the operation of the KOTRON-13 cyclotron. Results: The production of carbon-11 was enhanced from about 1.700 mCi ($50{\mu}A$) to 2,000 mCi ($60{\mu}A$) on the carbon-11 target which developed by seoul national university bundang hospital (SNUBH) and Samyoung Unitech. Additionally, the cooling condition was showed stable to produce carbon-11 under high beam current. Conclude: The carbon-11 target system of the KOTRON-13 cyclotron was successfully developed and improved carbon-11 production. Consequently, the operation of carbon-11 target system was highly effective and stable compare with other commercial cyclotrons. Our results are believed that this optimal carbon-11 target system will be helpful for the routine carbon-11 production in the KOTRON-13 cyclotron.

• Journal of the Korean earth science society
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• v.37 no.6
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• pp.373-386
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• 2016

This study aims to investigate the kinds of content and science communication included in the exhibits and the exhibition panels in order to suggest a direction of desirable educational development in the nuclear power information halls in Korea. The four local nuclear power information halls in Korea and the nuclear power science center in Japan are selected as the subject. The results of this study show that the 'conceptual' exhibits are a dominant topic among the four topics of contents, and the concept (CON) and interest (INT) are found as the most dominating component of science communication. Meanwhile, the nature of science (NOS), awareness (AW), enjoyment (ENJ), and opinion (OP) components are little exhibited. The findings of this study indicate that the nuclear power information halls can be more professional to enhance scientific literacy, as the informal education institutions, providing information of nuclear energy and radiation on various perspectives for visitors to make decisions by themselves and to improve their scientific attitudes and understanding of science communication. In addition, the limited science communication can be fully reinforced by docents or commentators. Further research needs to investigate the development of a specialized program to produce professional docents or commentators.

• The Korean Journal of Nuclear Medicine Technology
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• v.25 no.1
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• pp.41-43
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• 2021

Purpose In nuclear medicine blood tests, hemolysis samples are considered as inappropriate sample and are recommended not to be used for blood test. So, the lab are required to collect the blood again in the blood collection room However, The effect of hemolyzed samples on radioimmunoassay has not studied yet. This study was designed to evaluate effects of hemolysis on radioimmunoassay. Materials and Methods The kit manuals of 23 test items were reviewed to confirm whether hemolyzed samples were used. The subjects were 19 general applicants(male : 9, female : 13) and the samples were collected by each two SST tubes, one tube was obtained by centrifugation normally, and the other was obtained hemolyzed sample by centrifugation after external shock. It has been known that highly hemolyzed samples can affect the test results, so the test was performed using the severe hemolyzed sample. The test was performed for each test item using 23 normal serum and hemolysis serum, and SPSS19 program was used for statistical comparison of the test result. Results There was no significant difference between normal serum and hemolysis serum in 21 of 23 test items, but the results of insulin and C-peptide were significantly different(P<0.05). Conclusion It has been known that hemolysis in blood samples can affect the results of biochemical and hematological test, However, hemolysis effect is relatively low. Similarly, this study showed that hemolysis had not much effect on most of immunological radioimmunoassay except for some tests. Therefore, it is thought that the demand for re-collection due to hemolysis will be reduced in the laboratory, which will improve the work process of the laboratory.