• Title/Summary/Keyword: North pacific

Search Result 687, Processing Time 0.026 seconds

Association of a p53 Codon 72 Gene Polymorphism with Environmental Factors and Risk of Lung Cancer: a Case Control Study in Mizoram and Manipur, a High Incidence Region in North East India

  • Saikia, Bhaskar Jyoti;Das, Mandakini;Sharma, Santanu Kumar;Sekhon, Gaganpreet Singh;Zomawia, Eric;Singh, Yanglem Mohen;Mahanta, Jagadish;Phukan, Rup Kumar
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.24
    • /
    • pp.10653-10658
    • /
    • 2015
  • Background: A very high incidence of lung cancer is observed in Mizoram and Manipur, North East India. We conducted a population based case control study to establish associations of p53 codon 72 polymorphisms and interactions with environmental factors for this high incidence. Material and Methods: A total of 272 lung cancer cases and 544 controls matched for age (${\pm}5years$), sex and ethnicity were collected and p53 codon 72 polymorphism genotypes were analyzed using a polymerase chain based restriction fragment length polymorphism assay. We used conditional multiple logistic regression analysis to calculate adjusted odds ratios and 95% confidence intervals after adjusting for confounding factors. Results: p53 Pro/Pro genotype was significantly associated with increased risk of lung cancer in the study population (adjusted OR=2.14, CI=1.35-3.38, p=0.001). Interactions of the p53 Pro/Pro genotype with exposure to wood smoke (adjusted OR=3.60, CI=1.85-6.98, p<0.001) and cooking oil fumes (adjusted OR=3.27, CI=1.55-6.87, p=0.002), betel quid chewing (adjusted OR=3.85, CI=1.96-7.55, p<0.001), tobacco smoking (adjusted OR=4.42, CI=2.27-8.63, p<0.001) and alcohol consumption (adjusted OR=3.31, CI=1.10-10.03, p=0.034) were significant regarding the increased risk of lung cancer in the study population. Conclusions: The present study provided preliminary evidence that a p53 codon 72 polymorphism may effect lung cancer risk in the study population, interacting synergistically with environmental factors.

Facing Past and Present Challenges to Social & Economic Development (사회경제개발에 대한 과거와 현재 직면과제)

  • 성낙정
    • Explosives and Blasting
    • /
    • v.15 no.3
    • /
    • pp.14-19
    • /
    • 1997
  • Koreans have emphasized education as the primary means to reconstruct our country means to reconstruct our country after two catastrophic events-the Japanese occupation and the Korean War(1950-1953). A Strong belief- in education coupled with sheer deter-mination spurred the period of industrial and eeonomic development that started in the early 1970-'s. The "can-do" attitude of the general public was matched and aided by small S & T communities. Scientists and engineers provided the neeessary expertise to manufacture goods and process the many raw materials imported from overseas. After nearly three decades of reconst-ructing our completely devastated country, Korea has become a modern, cosmo-politan, fast-paced and dynamic country. In order to further increaser our manufac- turing capabilities and double the per-capita income by the beginning of the 21st century, we must improve productivitiy and encourage creatitivity in all sectors of our country. The S & T community's efforts in research and development. education, and interna-tional cooperation will be invaluable in determining our direction and reaching these goals. The general public is eager to peacefully unite our foreign powers since 1945. Toward that end. members of the S & T community are willing to coope-rate with our north Korean counterparts in all areas of S & T with the exception of defense related endeavors. Establi-shing scientific ties with north Korea will result in mutual economic benefit and greater regional stability in East Asia. In particular. scientists and manu-facturers in each province are eager to initiate cordial and professional relation-ships with north Korea in the hopes of securing these benefits. The Korean Federation of Science and Technology Societies(KOFST) has played an important role both in developing S & T policies, and in gostering the frowty of S & T societies. A non-governmental umbrella organization composed of over 251 professional societies, KOFST facili-tates the transfer of research outcomes and technology from research institutions to the various industries. KOFST also seeks to increase cooperation between the countries of the Pacific Rim. As evidence of that, we have pursued joint research and industrial ventures with China. Established projects include those on environmental conditions in the Yellow Sea, and improvement of aircraft manufacturing, telecommunica-tion equipment, and agricultural produ-cts. Increased cooperation between the Pacific Rim countries, particularly in S & T, would foster social and economic development for the region as a whole.

  • PDF

Dynamic Characteristics of Water Column Properties based on the Behavior of Water Mass and Inorganic Nutrients in the Western Pacific Seamount Area (서태평양 해저산 해역에서 수괴와 무기영양염 거동에 기초한 동적 수층환경 특성)

  • Son, Juwon;Shin, Hong-Ryeol;Mo, Ahra;Son, Seung-Kyu;Moon, Jai-Woon;Kim, Kyeong-Hong
    • Journal of the Korean Society for Marine Environment & Energy
    • /
    • v.18 no.3
    • /
    • pp.143-156
    • /
    • 2015
  • In order to understand the dynamic characteristics of water column environments in the Western Pacific seamount area (approximately $150.2^{\circ}E$, $20^{\circ}N$), we investigated the water mass and the behavior of water column parameters such as dissolved oxygen, inorganic nutrients (N, P), and chlorophyll-a. Physico-chemical properties of water column were obtained by CTD system at the nine stations which were selected along the east-west and south-north direction around the seamount (OSM14-2) in October 2014. From the temperature-salinity diagram, the main water masses were separated into North Pacific Tropical Water and Thermocline Water in the surface layer, North Pacific Intermediate Water in the intermediate layer, and North Pacific Deep Water in the bottom layer, respectively. Oxygen minimum zone (OMZ, mean $O_2$ $73.26{\mu}M$), known as dysoxic condition ($O_2<90{\mu}M$), was distributed in the depth range of 700~1,200 m throughout the study area. Inorganic nutrients typified by nitrite + nitrate and phosphate showed the lowest concentration in the surface mixed layer and then gradually increased downward with representing the maximum concentration in the OMZ, with lower N:P ratio (13.7), indicating that the nitrogen is regarded as limiting factor for primary production. Vertical distribution of water column parameters along the east-west and south-north station line around the seamount showed the effect of bottom water inflowing at around 500 m deep in the western and southern region, and concentrations of water column parameters in the bottom layer (below 2,500 m deep) of the western and southern region were differently distributed comparing to those of the other side regions (eastern and northern). The value of Excess N calculated from Redfield ratio (N:P=16:1) represented the negative value throughout the study area, which indicated the nitrogen sink dominant environments, and relative higher value of Excess N observed in the bottom layer of western and southern region. These observations suggest that the topographic features of a seamount influence the circulation of bottom current and its effects play a significant role in determining the behavior of water column environmental parameters.

Effect of Venture Business Tendency of North Korea Refugee Families on Adaptation to South Korean Society and Family Health (북한이탈주민의 벤처창업 성향이 남한사회 적응성과 가족건강성에 미치는 영향)

  • Choi, Baek Man;Byun, Sang Hae
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.10 no.2
    • /
    • pp.69-76
    • /
    • 2015
  • This paper aims to analyze how the Venture Business Tendency of North Korean refugees affects social adaptation and family health, and to provide proposals for policy making on the issue. For the purpose, we specifically suggest analysis of activation plan that 48 Venture Business North Korean managed Enterprise types, Entrepreneur type, Business type, Gender, Profit etc. As a result of analysis of actual proof, First, The Venture Business North Korean refugees managed need to consult to be technology business professionally because they features to be self-employment than expertise and knowledge basis type. Second, the rate of success of North Korean refugees is researched that female is higher than male. Third, to support Venture Business of North Korean refugees, they need one on one incubating support syspen why they are inexperienced in network, technical skills. Fourth, Venture Business Tendency of North Korean refugees affects social adaptation and family health. Since mid 1990's, North Korean refugees have come to South Korea through China or third countries due to collapsing economy of North Korea. In an effort to help those escaping from North Korea, the Seoul government provided them with a 3-month settlement program. But they have had experienced difficulties in communication, cultural assimilation, and confusion in their value system and identity. For the purpose, one-on-one interview was carried out on 45 North Korean refugees living in Seoul and neighboring cities, and the interviewed group was classified into three categories: single households, single-parent families and families with parents. The study findings demonstrated four policy alternatives to help improve quality of life of North Korean refugees and to help their successful settlemen.

  • PDF

Decadal Change of Frequency in Korea Landfalling Tropical Cyclone Activity (한반도에 상륙한 태풍 빈도수의 십년간 변동 특성)

  • Choi, Ki-Seon;Cha, Yu-Mi;Kim, Tae-Ryong
    • Journal of the Korean earth science society
    • /
    • v.33 no.1
    • /
    • pp.49-58
    • /
    • 2012
  • Through a statistical change-point analysis, this study found that Korea landfalling tropical cyclone (TC) frequency has increased rapidly since 1981. This increase is due to the following phenomenon. When anomalous cyclone is developed in the East Asian continent, anomalous anticyclone is reinforced in the western Pacific, which is related to the eastward shift of western North Pacific high, and thus anomalous southerly is formed to Korea from low-latitudes. This anomalous southerly plays an important role as steering flow in moving TCs toward Korea. To examine the cause of the development of anomalous cyclone in the East Asian continent, this study analyzed the water equivalent of accumulated snow depth during the preceding spring (March to May). As a result, less snow depth is observed in most regions of the East Asian continent than before 1981. Therefore, anomalous cyclone in the East Asian continent in summer can be reinforced by the land heating from the preceding spring and then the steering flow of anomalous southerly that moves TCs toward Korea can be also developed to Korea from low-latitudes in summer.

Analysis on the Variability of Korean Summer Rainfall Associated with the Tropical Low-frequency Oscillation (적도 저주파 진동과 관련된 한반도 여름철 강수의 변동성 연구)

  • Moon, Ja-Yeon;Choi, Youngeun;Park, Changyong
    • Journal of the Korean Geographical Society
    • /
    • v.48 no.2
    • /
    • pp.184-203
    • /
    • 2013
  • This study analyzes the variability of Korean summer rainfall associated with the tropical low-frequency oscillation using long-term observation data. From the EOF analysis, the first mode showed opposite phase between the South and the North Korea with the regime shift in rainfall variability since the mid-1990s. The summer precipitation over South Korea tends to increase in southern part during strong El Ni$\tilde{n}$o where the warm sea surface temperature extends to far eastern tropical Pacific. In weak La Ni$\tilde{n}$a, the increased precipitation directly influences from the western tropical Pacific to the mid-latitude. In June, the rainfall over South Korea is positively correlated with the Indian Summer Monsoon while in July, it is negatively correlated with the Western North Pacific Summer Monsoon. In August, highly negative correlation between the rainfall over South Korea and the Indian Summer Monsoon is found.

  • PDF

Predictability of Northern Hemisphere Teleconnection Patterns in GloSea5 Hindcast Experiments up to 6 Weeks (GloSea5 북반구 대기 원격상관패턴의 1~6주 주별 예측성능 검증)

  • Kim, Do-Kyoung;Kim, Young-Ha;Yoo, Changhyun
    • Atmosphere
    • /
    • v.29 no.3
    • /
    • pp.295-309
    • /
    • 2019
  • Due to frequent occurrence of abnormal weather, the need to improve the accuracy of subseasonal prediction has increased. Here we analyze the performance of weekly predictions out to 6 weeks by GloSea5 climate model. The performance in circulation field from January 1991 to December 2010 is first analyzed at each grid point using the 500-hPa geopotential height. The anomaly correlation coefficient and mean-square skill score, calculated each week against the ECWMF ERA-Interim reanalysis data, illustrate better prediction skills regionally in the tropics and over the ocean and seasonally during winter. Secondly, we evaluate the predictability of 7 major teleconnection patterns in the Northern Hemisphere: North Atlantic Oscillation (NAO), East Atlantic (EA), East Atlantic/Western Russia (EAWR), Scandinavia (SCAND), Polar/Eurasia (PE), West Pacific (WP), Pacific-North American (PNA). Skillful predictability of the patterns turns out to be approximately 1~2 weeks. During summer, the EAWR and SCAND, which exhibit a wave pattern propagating over Eurasia, show a considerably lower skill than the other 5 patterns, while in winter, the WP and PNA, occurring in the Pacific region, maintain the skill up to 2 weeks. To account for the model's bias in reproducing the teleconnection patterns, we measure the similarity between the teleconnection patterns obtained in each lead time. In January, the model's teleconnection pattern remains similar until lead time 3, while a sharp decrease of similarity can be seen from lead time 2 in July.

How to Manage the Economic Cooperation between the South-North Korean Corporations in the Era of Economic Crisis (경제위기와 남북 기업 활동의 협력 방안)

  • Sung, Sang-Hyeon;Lee, Jong-Keon
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.7 no.2
    • /
    • pp.91-99
    • /
    • 2012
  • The political conflicts and military collisions between the South-North Korea resulted in actions taken at 1 of Dec. in 2008 and 24 May in 2010. Those actions stopped the major economic cooperations such as the relink of a railroad line across the divided peninsula as well as Mt. Geumgang tourist trade, and cast shade on the Gaesung Industrial Complex. This article articulates the current situation of the economic damages, status quo of cooperation and the South Koreans' changed way of thinking about issues between the South and North which provoked by the conflicts. We emphasized the necessities of minimizing unstable non-economic factors on the Peninsula; continuing win-win economic cooperation between the South-and North corporations; guaranteeing safe business conditions; improving the relationship based on the national consensus. Also we suggested ideas on how to manage the economic cooperation and how to explore new business opportunities in the future based on entrepreneurial leadership.

  • PDF

Cruise Report on TAO Real-time Monitoring Buoy System in the Pacific Ocean in April 2010 (2010년 4월 TAO 해양관측부이 시스템에 관한 탐사보고)

  • Kim, Dong-Guk;Kim, Seon-Jeong;Lee, Ha-Woong
    • Ocean and Polar Research
    • /
    • v.33 no.4
    • /
    • pp.507-516
    • /
    • 2011
  • Tropical Atmosphere Ocean/Triangle Trans-Ocean Buoy Network (TAO/TRITON) Array is the series of buoys for the international ocean research project, which is mostly supported by National Ocean and Atmosphere Administration (NOAA) and Japan Agency for Marine-Earth Science and Technology (JAMSTEC). We can determine the effect of the equatorial and Pacific Ocean conditions on global climate change from buoy array measurement data. The TAO/TRITON array comprises around 70 measurement buoys from $10^{\circ}$ north to $10^{\circ}$ south in the tropics and between Galpagos and New Guinea. NOAA maintains ATLAS buoys in the central and eastern Pacific between $165^{\circ}E$ and $95^{\circ}W$, and JAMSTEC maintains the 12 buoys in the western Pacific along $137^{\circ}E$, $147^{\circ}E$, and $156^{\circ}E$. The KA-10-03 cruise excursion provided us with a good opportunity to obtain knowledge on oceanic buoy operation and maintenance. Further, we learned advanced techniques and know-how on buoy operation and maintenance. Once we are confident with our buoy management and maintenance techniques, both KORDI and NOAA technicians may be able to help each other when needed and share available resources.

The Intensification of Walker Circulation over the Past 15 Years from 1999 and Its Relation to TC Activity in the Western North Pacific

  • Choi, Jae-Won;Cha, Yumi;Kim, Jeoung-Yun
    • Journal of the Korean earth science society
    • /
    • v.37 no.6
    • /
    • pp.359-372
    • /
    • 2016
  • The time-series of Walker circulation index (WCI) in this study shows the strengthening of the Walker circulation in recent years. To further understand the large-scale features related to the WCI strengthening, a difference between the averaged meteorological variables in two time periods 1999-2013 and 1984-1998 is analyzed. The difference in 850 hPa stream flows between the two periods shows that the anomalous easterlies (anomalous trade wind) are dominant due to the strengthening of anomalous anticyclonic circulations at the subtropical Pacific of both hemispheres. The difference between the averaged zonal atmospheric circulations over $5^oS-5^oN$ in the two periods confirms that upward flows are strengthened at the tropical western Pacific and downward flows are strengthened at the tropical central and eastern Pacific in recent years. It matches the WCI strengthening in recent years. The time-series of tropical cyclone (TC) genesis frequency from July to September shows that a mean TC genesis frequency from 1999-2013 decreases compared to that of the time period 1984-1998. The monsoon trough in the period 1984-1998 was located in the further east direction and stronger than that in the period 1999-2013. TCs in the recent period that are generated in further west than TCs in the past period moved from the west. Thus, the TC intensity along the coasts in East Asia becomes weaker in recent period. The intensification of Walker circulation in recent years is related to the weaker TC intensity in East Asia through strengthened anomalous anticyclones at the subtropical western Pacific.