We hypothesized that the unsaturated fatty acid palmitoleic acid (POA) could promote the expression of adipogenic/lipogenic genes in bovine skeletal muscle satellite cells (BSCs). The BSCs were cultured in a growth medium containing 10% fetal bovine serum. When the cells reached 80%-90% confluence, we used the differentiation medium with 5% horse serum for differentiation for 96 h. The differentiation medium contained 50 µM, 100 µM and 200 µM POA. Control BSC were cultured only in differentiation media. Compared with the control BSC, the POA BSC significantly up-regulated the expression of paired box 3 (Pax3) and paired box 7 (Pax7) and down-regulated myogenin gene expression (p < 0.01), which indicates a depression in muscle fiber development. However, all POA treatments up-regulated the expression of the adipocyte transcription factors peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer-binding protein alpha and beta (C/EBP α and C/EBP β), and other genes (p < 0.01) and increased the expression of PAT-family proteins and the concentration of adiponectin in the media. These results indicate that POA can convert part of BSCs into adipocytes.
Despite continuous volatility in ideological leanings, South Korean governments, conservative or progressive, have published a series of plans for aiding the economic development of North Korea. The Moon administration's plan is the paragon of such efforts. In addition, recent detente between the North Korean regime and the US government evokes much hope in its success. There is, hidden behind the veil of hope, apprehension about the crisis of management of cultural heritage in the North Korean region. It is believed that development policies may overwhelm efforts at conservation of cultural heritage, in particular that the hurrying of development projects would provoke insufficient and inappropriate investigation of archaeological sites., If these problems arise, responsibility for their resolution would be carried by South Korean archaeologists and governmental institutes. This paper reviews what the South Korean government has suggested for North Korea's economic recovery and examines what capability the South Korean archaeology sector has for investigating North Korean cultural heritage. It then discusses the scale of investigation needed, and what should beused as precedent in planning substantial excavations when development projects are performed in the North Korean region. Constructing a digital map system for cultural heritage of North Korea is suggested as one of the most urgent tasks precedent to substantial excavations. It is of great importance because we do not currently have any substantial information about the locations and current condition of cultural heritage sites and artifacts in the North Korean region. The mapping of Bronze Age sites in North Korea, conducted as a sort of pilot test, revealed that archaeological sites are densely distributed in several regions, especially Hwanghae-do and Pyoyang Directly-Administrated City, and that there is high potential of discovering new sites.
Kui Hu;Xubo Ma;Teng Zhang;Xuan Ma;Zifeng Huang;Yixue Chen
Nuclear Engineering and Technology
/
제55권8호
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pp.2785-2796
/
2023
How to generate the precise broad group cross section is important for the fast reactor design. In this study, a fast reactor multi-group cross-section generation code MGGC2.0 are developed in-house for processing ultrafine group MATXS format library. Validation and verification are performed for MGGC2.0 code by applying the benchmarks of ICSBEP handbook, and the results of MGGC2.0 agree well with that of MCNP. The consistent PN method with critical buckling search is in good agreement that condensed with TWODANT flux and flux moment for the inner core and outer core region. For the radial blanket and reflector, two region approximation method has been applied in MGGC2.0 by using collision Probability Method neutron flux solver. The RBEC-M benchmark was used to verify the power distribution calculation, and the relative error of power distribution comparison with the reference are less than 0.8% in the fuel region and the maximum relative error is 5.58% in the reflector region. Therefore, the precise broad cross section can be generated by MGGC2.0 for fast reactor.
A typical snowfall pattern occurs over the east coastal region of the Korean Peninsula, known as the Yeongdong region. The precipitation over the Yeongdong region is influenced by the cold and dry northeasterly wind which advects over warm and moist sea surface of the East Sea of Korea. This study reveals the influence of large-scale factors, affecting local to remote areas, on the mesoscale snowfall system over the Yeongdong region. The National Centers for Environmental Prediction-Department of Energy reanalysis dataset, Extended Reconstructed sea surface temperature, and observed snowfall data are analyzed to reveal the relationship between February snowfall and large-scale factors from 1981 to 2014. The Yeongdong snowfall is associated with the sea level pressure patterns over the Gaema Plateau and North Pacific near the Bering Sea, which is remotely associated to the sea surface temperature (SST) variability over the North Pacific. It is presented that the relationship between the Yeongdong snowfall and large-scale factors is strengthened after 1999 when the central north Pacific has warm anomalous SST. These enhanced relationships explain the atmospheric patterns of recent strong snowfall years (2010, 2011, and 2014). It is suggested that the newly defined index in this study based on related SST variability can be used for a seasonal predictor of the Yeongdong snowfall with 2-month leading.
The ACE Engineering, Inc. (ACE) of Seoul, Korea and The Energy Systems Institute (SEI) of Irkutsk, Russia has extensively studied the formation of an interconnected electric power systems throughout the North Eastern Asia Region(NEAR). The region encompasses East Siberia (ESR), Far East of Russia(FER), North East China(NEC), Mongolia(MON), North Korea(NKOR), South Korea(SKOR). Although geographically adjacent to each other, these countries and territories have different levels and rates of economic development, possess different reserves of energy resources which complement each other and hence, can interact to their mutual benefits. This Project is called Peace Network Project (PNP) because it seems to contribute for development of power economy and clean environment. In a word, the PEACE Network is expected to serve as "Power Economy And Clean Environment Network" and to promote the international cooperation. to expedite the peaceful reunification of North & South Korea and to revive the Korean culture in the North, and eventually contribute to the human prosperity.
A strong negative correlation has been detected between the North Pacific Oscillation Index (NPI) and the Effective Drought Index (EDI) in May over Korea. In May of positive NPI year, anomalous patterns caused a drought in Korea as follows: the anomalous south-low, north-high low-level pressure patterns in the northeast and southeast of Korea have strengthened the anomalous northerlies to Korea. In addition, these anomalous northerlies have prevented western North Pacific (WNP) high from moving northward. As a result, anomalous descending flows have strengthened in the mid-latitude region in East Asia. In the WNP, the anomalous south-high, north-low sea surface temperature (SST) has been widely distributed, which has strengthened anomalous south-low, north-high low-level pressure patterns. These anomalous characteristics of pressure and SST patterns observed in May of positive NPI years have already been detected in previous winter (December-February) and early spring (March, April). In addition, the anomalous negative sea ice concentration in the North Pacific during two seasons has strengthened the anomalous anticyclonic circulation in the same region and in turn made a contribution to formation of anomalous south-low, north-high pressure patterns in May.
In order to reserve abundant germplasm for breeding new corn varieties, major characteristics of ears and kernels were evaluated with a total of 210 Korean indigenous maize lines collected from various parts of Pusan City and Kynugnam Province, Korea The average ear length and ear diameter of indigenous maize lines collected was 12.52cm and 3.33 cm, respectively. The average ear weight of the maize lines was 63.70g. The ears collected from the north-west mountainous region were the heaviest, and The ears from the south coastal region were the lightest. The average kernel weight per ear was 50.54g, and the kernel weight per ear by region showed a tendency similar to the ear weight. The kernels of maize lines collected in the north-west mountainous region were the longest, and kernel width and thickness were the largest in the west plain region. 100 kernel weight and embryo weight the largest in the lines collected in the north-west mountainous region. The degree of pericarp thickness was the smallest in the lines collected in the south coastal region, and largest in the lines collected in the west plain region. Except for the correlation coefficient width and 100 kernel weight, all correlation coefficients between the characteristics of the lines showed highly significant differences.
Ciglitazone is a member of the thiazolidinedione family, and specifically binds to peroxisome proliferator-activated receptor-γ (PPARγ), thereby promoting adipocyte differentiation. We hypothesized that ciglitazone as a PPARγ ligand in the absence of an adipocyte differentiation cocktail would increase adiponectin and adipogenic gene expression in bovine satellite cells (BSC). Muscle-derived BSCs were isolated from six, 18-month-old Yanbian Yellow Cattle. The BSC were cultured for 96 h in differentiation medium containing 5 µM ciglitazone (CL), 10 µM ciglitazone (CM), or 20 µM ciglitazone (CH). Control (CON) BSC were cultured only in a differentiation medium (containing 2% horse serum). The presence of myogenin, desmin, and paired box 7 (Pax7) proteins was confirmed in the BSC by immunofluorescence staining. The CL, CM, and CH treatments produced higher concentrations of triacylglycerol and lipid droplet accumulation in myotubes than those of the CON treatment. Ciglitazone treatments significantly increased the relative expression of PPARγ, CCAAT/enhancer-binding protein alpha (C/EBPα), C/EBPβ, fatty acid synthase, stearoyl-CoA desaturase, and perilipin 2. Ciglitazone treatments increased gene expression of Pax3 and Pax7 and decreased expression of myogenic differentiation-1, myogenin, myogenic regulatory factor-5, and myogenin-4 (p < 0.01). Adiponectin concentration caused by ciglitazone treatments was significantly greater than CON (p < 0.01). RNA sequencing showed that 281 differentially expressed genes (DEGs) were found in the treatments of ciglitazone. DEGs gene ontology (GO) analysis showed that the top 10 GO enrichment significantly changed the biological processes such as protein trimerization, negative regulation of cell proliferation, adipocytes differentiation, and cellular response to external stimulus. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that DEGs were involved in the p53 signaling pathway, PPAR signaling pathway, biosynthesis of amino acids, tumor necrosis factor signaling pathway, non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, and Wnt signaling pathway. These results indicate that ciglitazone acts as PPARγ agonist, effectively increases the adiponectin concentration and adipogenic gene expression, and stimulates the conversion of BSC to adipocyte-like cells in the absence of adipocyte differentiation cocktail.
Journal of Fisheries and Marine Sciences Education
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제3권2호
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pp.73-82
/
1991
In recent years, the communication and the trade between the Republic of Korea(South Korea) and the Communist bloc has been activated. The simultaneous entrance of South Korea and North Korea to the United Nations will accelerate the political dialogue and also the trade which is indirectly carried out through a third country at present will be turned into direct way. Fisheries products are also treated as one of the important trade goods and there is a hopeful prospect that the amount of trade will be steeply increased in the near future. Furthermore, there is a great possibility of development up to the joint utilization of fishing grounds or the joint investment in fisheries projects. Concerning such points, since it is very much important to understand the present status of fisheries in North Korea, the author made a study on this field as requested by the Board of Unification, and report a part of the study here. The prominent character of North Korea's ruling sea area is that the sea is completely separated into two regions-the East Sea Region and the West Sea Region-and no continuity exists between them. The East Sea Region locates in the fringe of the biggest fishing ground of the world-the North Pacific Ocean-and very rich in resources not only warm water fishes but also cold water fishes. Especially alaska pollack, Theragra chalcogramma, is caught abundantly in this region. Contrary to that, fishing activity in the West Sea Region seems to be interrupted in winter. Even though some valuable warm water fishes-yellow corvenia, Pseudosciaena manchurica, and hair tail, Trichiurus lepturus, and so forth-come to this region from spring to summer along the coast line of this region for spawning, and vigorous fishing activity is carried out. But the most of them migrate southward to the neighboring waters of Cheju Island for wintering from autumn to winter, and so the fishing activity in this region seems to be interrupted greatly during winter. The total number of fishing boats in North Korea is estimated at 36 thousand and the rate of mechnization at about 70% compared with 99 thousand and 78% in South Korea. North Korea proclaimed an exclusive economic zone of 200 nautical miles in 1977. Specific character of this zone is setting of military boundary zone, up to 50 miles from the base line in the East Sea Region and also it covers whole region of the economic zone in the West Sea Region. Especially in the East Sea Region she set up a straight base line which can not be permissible by the international law. North Korea's statistics on fisheries product has not been announced officially on account of her unique isolationism, but it can be estimated through several data procured. At the first, the amount of fisheries products in the North Korea is reported as about 1.7 million ${\frac{M}{T}}$ by Fisheries Statistics which issued by the FAO in 1987, but a North Korea's trade organization announced the amount as 3.5 million ${\frac{M}{T}}$ in 1988. The former seems to be underestimated and the latter must be an exaggeration. According to Chikuni, who is a Japanese worker for FAO, prepared the unofficial statistics based on the evidence which he collected through the fineries development plan of the FAO/UNDP, and estimated the mean amount between 1982 and 1984 was 2.4 million ${\frac{M}{T}}$ or so. The Board of Unification estimated on the basis of various factors that the amount was 2.2 million ${\frac{M}{T}}$ or so in 1987 and in 1988. This seems to be the most reasonable. To solve the chronic lack of foreign currency, North Korea makes effort on the development of fisheries, and has even aimed fisheries product at 11 million ${\frac{M}{T}}$ by 1993, but this target looks unrealistic under the present circumstances. Somehow, we can exploit her extreme policy which has gone so far as to establish such an excessive and impractical target. Nevertheless this will be helpful to promote the joint development of the fishery activity between South Korea and North Korea.
This paper quantitatively analyzes the current status of North Korean consumer payment instruments through a questionnaire survey of 292 North Korean defectors. In the 2010s, it was found that the payment experience ratio of domestic currency cash and grain decreased, while the payment experience ratio of foreign currency cash increased. The use of foreign currency reached a stage where it was spread not only as a store of value but also as a medium of exchange. However, the most frequently used payment instrument by North Korean consumers was still domestic currency cash. By region, in inland urban areas both domestic currency cash and U.S. dollars are used and in the North Korea-China border region both domestic currency cash and Chinese yuan are used, while in inland rural areas dollarization does not occur because both domestic currency cash and grain are used. Meanwhile, despite the stable price trend during 2013-2019, the dollarization hysteresis effect is appearing, and both the purchasing power risk theory and the network externality theory are considered to have explanatory power for the cause. The results of this paper suggest that as dollarization is intensifying, it is expected that more costs such as shortages of commodities will be incurred than in the past if North Korea's de-dollarization policy is reimplemented. Also, in the case of domestic currency cards, which the North Korean authorities introduced in 2015 as part of a means of financial reform, this paper suggests that it may continue to be difficult for domestic currency cards to normalize official finance under the dollarization hysteresis.
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