• 당뇨병
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• 제19권3호
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• pp.135-139
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• 2018

The sodium-glucose cotransporter-2 inhibitor (SGLT2i) is a new anti-hyperglycemic agent that have function to concomitantly inhibit the reabsorption of glucose and sodium in the renal proximal convoluting tubule. Recent two cardiovascular outcome trials showed that a lower risk of cardiovascular events with SGLT2i in people with type 2 diabetes. In addition, prior real-world data demonstrated similar SGLT2i effects, but these studies were limited to the United States and Europe. Thus, the CVD-REAL (Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors) 2 Study was investigated cardiovascular outcomes in those initiated on SGLT2i versus other glucose-lowering drugs (oGLDs) across 6 countries in the Asia Pacific, the Middle East, and North American regions. In Korea, 336,644 episodes of initiation in SGLT2i or oGLD group between September 2014 and December 2016 were identified in Korea National Health Insurance database after propensity score matching. SGLT2i users was associated with a lower risk of all-cause death (hazard ratio [HR], 0.72; 95% confidence interval [CI], 0.67~0.77), hospitalization for heart failure (HHF) (HR, 0.87; 95% CI, 0.82~0.92), all-cause death or HHF (HR, 0.81; 95% CI, 0.78~0.85), myocardial infarction (HR, 0.81; 95% CI, 0.74~0.89), and stroke (HR, 0.82; 95% CI, 0.78~0.86) compared with oGLD users. In conclusion, initiation of SGLT2i had a lower risk of cardiovascular events in people with type 2 diabetes compared with oGLDs.

• 한국항만경제학회지
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• 제23권2호
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• pp.1-24
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• 2007

빠른 경제성장과 교역량의 증가에 힘입어 중국은 이제 세계에서 가장 많은 컨테이너 물동량을 처리한 국가가 되었다. 그리고 컨테이너선의 대형화와 신속화 추세에 발맞추어 동북아 주요항만이 직면하는 환경도 상당히 빠르게 변하고 있다. 상해항은 육지로부터 약 30km 떨어진 대양산과 소양산을 개발하여 2005년 말에 제1기 터미널을 그리고 2006년에 제2기 터미널을 개장하였다. 그리고 2012년까지 전체 29선석을 조성하여 1,500만 TEU를 처리할 예정으로 있다. 컨테이너 처리물량에서 부산항을 추월한 상해항은 2,006년도 연간 물동량을 약 2,170만 TEU를 처리하여 세계 제3위의 지위를 확고히 했으며, 향후 세계 제1위의 컨테이너 처리항만으로 부상할 것으로 보인다. 세계 제5위의 컨테이너 처리항만이고, 동북아 중심항만이 되고자 하는 부산항에 양산항의 개장 및 향후 개발 계획에 따른 주변 상황에 능동적으로 대처하기 위한 다양한 대응전략을 제시해 본다.

• 대기
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• 제29권2호
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• pp.115-129
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• 2019

Surface winds over the ocean influence not only the climate change through air-sea interactions but the coastal erosion through the changes in wave height and direction. Thus, demands on a reliable projection of future changes in surface winds have been increasing in various fields. For the future projections, climate models have been widely used and, as a priori, their simulations of surface wind are required to be evaluated. In this study, we evaluate the climatological mean surface winds over the Korean Waters simulated by five regional climate models participating in Coordinated Regional Climate Downscaling Experiment (CORDEX) for East Asia (EA), an international regional climate model inter-comparison project. Compared with the ERA-interim reanalysis data, the CORDEX-EA models, except for HadGEM3-RA, produce stronger wind both in summer and winter. The HadGEM3-RA underestimates the wind speed and inadequately simulate the spatial distribution especially in summer. This summer wind error appears to be coincident with mean sea-level pressure in the North Pacific. For wind direction, all of the CORDEX-EA models simulate the well-known seasonal reversal of surface wind similar to the ERA-interim. Our results suggest that especially in summer, large-scale atmospheric circulation, downscaled by regional models with spectral nudging, significantly affect the regional surface wind on its pattern and strength.

• 한국지구과학회지
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• 제40권4호
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• pp.414-427
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• 2019

In East Asia, the long-range transport of dust storms originating from Mongolia and northern China affects airborne dust loadings over downwind areas in the southern Korean Peninsula. Since 1997, dust loading cases caused by dust storms have been observed using the thresholds of total suspended particles (TSP, ${\geq}250{\mu}g\;m^{-3}\;hr^{-1}$) and particulate matter less than $10{\mu}g$ ($PM_{10}$, ${\geq}190{\mu}g\;m^{-3}\;hr^{-1}$) in the central-southern Korean Peninsula. There were two dust loading cases that exceeded these thresholds in 2016 and three in 2017, which reflects the downward trend of the last twenty-one years in the central-southern Korean Peninsula. Furthermore, five other dust loading cases with mass concentrations lower than the thresholds were observed from 2016 to 2017. In the moderate dust loading cases exceeding the thresholds, a descending motion of cut-off lows below $45^{\circ}N$ and a southward trough at 500 hPa gpm isopleths intensified at the western ridge, and largely extended the surface high-pressure system over southeast China. Airborne dust loadings following pronounced north-westerlies in the forward side of the high-pressure system were transported to the surface of the central-southern Korean Peninsula. However, in slight dust loading cases lower than the thresholds, the restricted descending motion of cut-off lows over $45^{\circ}N$ and the southwestward trough at 500 hPa gpm isopleths intensified the zonal flow over the Korean Peninsula. Surface high- and low-pressure systems moved eastward from the source compared to moderate dust loading cases. Due to the zonal movement of dust storms traversing eastern China, slight dust loading cases were observed with relatively higher ratios of $PM_{2.5}/TSP$ and carbon monoxide (CO) in the central-southern Korean Peninsula.

• 한국기후변화학회지
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• 제7권1호
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• pp.49-57
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• 2016

In the present study, the time series of the number of days on which temperatures were not higher than $-5^{\circ}C$ in winter in Seoul was analyzed. The results showed a decreasing tendency until recently. Statistical change-point analysis was conducted to examine whether climate regime shifts existed in this time series. According to the results, the number of days on which temperatures were not higher than $-5^{\circ}C$ in winter in Seoul drastically decreased since 1988. Therefore, to find out the reason for the recent decrease in the number of days, differences between the means of large-scale environments in winder during 1988~2010 and those during 1974~1987 were analyzed. In all layers of the troposphere, anomalous anticyclones developed in regions around the Korean Peninsula and thus the Korean Peninsula was affected by westerlies or south-westerlies. This was associated with the recent a little further northward development of western North Pacific subtropical high. Therefore, environments good for warm and humid air to flow into the Korean Peninsula were formed. To examine whether relatively warm and humid air actually flowed into the Korean Peninsula recently, temperatures and specific humidity in all layers in the troposphere were analyzed and according to the results the Korean Peninsula showed warm and humid anomalies. In the analyses of sensible heat net flux and maximum temperatures at a height of 2 m that can be felt by humans, the East Asia Continent including the Korean Peninsula showed positive anomalies.

• Journal of Animal Science and Technology
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• 제64권3호
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• pp.409-431
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• 2022

Various insects have emerged as novel feed resources due to their economical, eco-friendly, and nutritive characteristics. Fish, poultry, and pigs are livestock that can feed on insects. The digestibility of insect-containing meals were presented by the species, life stage, nutritional component, and processing methods. Several studies have shown a reduced apparent digestibility coefficient (ADC) when insects were supplied as a replacement for commercial meals related to chitin. Although the expression of chitinase mRNA was present in several livestock, indigestible components in insects, such as chitin or fiber, could be a reason for the reduced ADC. However, various components can positively affect livestock health. Although the bio-functional properties of these components have been verified in vitro, they show positive health-promoting effects owing to their functional expression when directly applied to animal diets. Changes in the intestinal microbiota of animals, enhancement of immunity, and enhancement of antibacterial activity were confirmed as positive effects that can be obtained through insect diets. However, there are some issues with the safety of insects as feed. To increase the utility of insects as feed, microbial hazards, chemical hazards, and allergens should be regulated. The European Union, North America, East Asia, Australia, and Nigeria have established regulations regarding insect feed, which could enhance the utility of insects as novel feed resources for the future.

• 대순사상과 동아시아종교
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• 제2권2호
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• pp.101-121
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• 2023

Daoism was introduced into the South-West of Vietnam via two main entries: the missionaries from North and Central Vietnam who migrated to the South by following the Southward movement and the spread of Daoism by Chinese migrant men who came and settled in the South-West of Vietnam from the late seventieth century to late nineteenth century. However, the biggest influence of Daoism in the Southwest of Vietnam was mainly the Chinese missionaries of Daoism. As time went by, together with the impacts of social and historical circumstances, Daoism had a strong influence on the lives of the South-West people in terms of different aspects, especially their faith and religions. The impact of Daoism into people's faith and religion was considerable, especially to the indigenous religions, of which the religion, Four Debts of Gratitude, is a representative example. With the aims of clarifying how Four Debts of Gratitude was influenced by Daoist thought and how the indigenous religions and systemized ideologies in the South-West of Vietnam were related during the period of living condition expansion as well as cohabitation of several ethnic groups in the region, this article focuses on Daoist thought expressed in typical symbols in the sacred architecture of the Four Debts of Gratitude such as Cổ Lầu, wine gourds, and the Eight Trigrams. Once properly examined, it becomes clear that the prominent symbols and other Daoist elements show that Daoism had a profound influence on the Four Debts of Gratitude.

• 대한족부족관절학회지
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• 제28권3호
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• pp.81-86
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• 2024

The International Federation of Foot and Ankle Societies (IFFAS) is a global organization for foot and ankle societies, comprising the Asian Federation of Foot and Ankle Surgeons (AFFAS), the European Foot and Ankle Society (EFAS), the Latin American Federation of Medicine and Surgery of the Foot and Leg (FLAMECIPP), the North American Federation of Foot and Ankle Societies (NAFFAS), and the Southern Federation of Foot and Ankle Society. Since 2005, IFFAS has organized worldwide conferences every three years, starting in Naples, Italy. The 2020 conference in Chile was postponed to 2022 due to COVID-19 pandemic and became biennial with the founding of the Southern Federation. Consequently, the conference is set to take place in Seoul in 2024. IFFAS 2024 was the first global foot and ankle conference held post-pandemic and significant as the first IFFAS event in Asia since the 2011 conference was canceled because of the Great East Japan Earthquake. Under the theme "Meet the knowledge and beautifulness," the event was hosted in Seoul. The academic program included an AFFAS-hosted event on May 30, followed by the IFFAS-hosted conference from May 31 to June 1, with all events organized by the Korean Foot & Ankle Society (KFAS).

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.8-9
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• 2017

Soybean yield has been low and unstable in Japan and other areas in East Asia, despite long history of cultivation. This is contrasting with consistent increase of yield in North and South America. This presentation tries to describe perspective of breaking stagnation of soybean yield in East Asia, considering the factors of the different yields between regions. Large amount of rainfall with occasional dry-spell in the summer is a nature of monsoon climate and as frequently stated excess water is the factor of low and unstable soybean yield. For example, there exists a great deal of field-to-field variation in yield of 'Tanbaguro' soybean, which is reputed for high market value and thus cultivated intensively and this results in low average yield. According to our field survey, a major portion of yield variation occurs in early growth period. Soybean production on drained paddy fields is also vulnerable to drought stress after flowering. An analysis at the above study site demonstrated a substantial field-to-field variation of canopy transpiration activity in the mid-summer, but the variation of pod-set was not as large as that of early growth. As frequently mentioned by the contest winners of good practice farming, avoidance of excess water problem in the early growth period is of greatest importance. A series of technological development took place in Japan in crop management for stable crop establishment and growth, that includes seed-bed preparation with ridge and/or chisel ploughing, adjustment of seed moisture content, seed treatment with mancozeb+metalaxyl and the water table control system, FOEAS. A unique success is seen in the tidal swamp area in South Sumatra with the Saturated Soil Culture (SSC), which is for managing acidity problem of pyrite soils. In 2016, an average yield of $2.4tha^{-1}$ was recorded for a 450 ha area with SSC (Ghulamahdi 2017, personal communication). This is a sort of raised bed culture and thus the moisture condition is kept markedly stable during growth period. For genetic control, too, many attempts are on-going for better emergence and plant growth after emergence under excess water. There seems to exist two aspects of excess water resistance, one related to phytophthora resistance and the other with better growth under excess water. The improvement for the latter is particularly challenging and genomic approach is expected to be effectively utilized. The crop model simulation would estimate/evaluate the impact of environmental and genetic factors. But comprehensive crop models for soybean are mainly for cultivations on upland fields and crop response to excess water is not fully accounted for. A soybean model for production on drained paddy fields under monsoon climate is demanded to coordinate technological development under changing climate. We recently recognized that the yield potential of recent US cultivars is greater than that of Japanese cultivars and this also may be responsible for different yield trends. Cultivar comparisons proved that higher yields are associated with greater biomass production specifically during early seed filling, in which high and well sustained activity of leaf gas exchange is related. In fact, the leaf stomatal conductance is considered to have been improved during last a couple of decades in the USA through selections for high yield in several crop species. It is suspected that priority to product quality of soybean as food crop, especially large seed size in Japan, did not allow efficient improvement of productivity. We also recently found a substantial variation of yielding performance under an environment of Indonesia among divergent cultivars from tropical and temperate regions through in a part biomass productivity. Gas exchange activity again seems to be involved. Unlike in North America where transpiration adjustment is considered necessary to avoid terminal drought, under the monsoon climate with wet summer plants with higher activity of gas exchange than current level might be advantageous. In order to explore higher or better-adjusted canopy function, the methodological development is demanded for canopy-level evaluation of transpiration activity. The stagnation of soybean yield would be broken through controlling variable water environment and breeding efforts to improve the quality-oriented cultivars for stable and high yield.

• 한국지역지리학회지
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• 제17권2호
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• pp.150-166
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• 2011

이 연구는 장마철 남해안 호우 사례의 850hPa 면 수증기 수송의 주축 유형에 대해 우리나라의 강수량 분포 특성, 동아시아 규모의 종관 특성과 장마전선의 구조를 밝히는 것을 목적으로 한다. 그 결과 유형 A(남중국해~화남~남해안)의 경우 아열대고기압이 화남지방에까지 영향을 미치고 황해를 중심으로 뚜렷한 저압부가 나타났다. 강수량도 대체로 동서 방향으로 분포하며 지형의 영향이 잘 나타나지 않았다. 유형 B(남중국해~타이완 부근~남해안), 유형 C(북태평양~남해안)에서는 타이완 부근에 열대저기압이 자주 나타났고 북서태평양고기압은 북쪽으로 이동하였다. 남해안 부근에서만 수증기 수송 주축이 나타나는 유형 D에서는 황해에 강한 저기압이 나타났다. 주축 유형 B, C, D의 경우 강수량 분포에서 북동~남서 방향이 잘 나타나며 지형의 영향이 뚜렷하게 나타났다. 상층 제트기류는 남해안의 북쪽에서 강화되었고 하층 제트기류는 수증기 수송 주축과 거의 일치하여 나타났다. 전선의 구조를 살펴본 즉, 거의 전체 사례에서 저기압성 순환이 대류권 상층에까지 나타나는 깊은 활동전선 유형을 보였다. 이 점에서 장마는 바이우계 동안 상당한 빈도로 얕은 활동전선 유형이 나타나는 일본 남서부 지역의 경우와 차이를 나타냈다.