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Study of SUVm Cut-off Value for the Distinction of Pancreatic Cancer In PET/CT Exam (PET/CT 검사에서 췌장암 판별을 위한 SUVm 경계값 연구)

  • Chang, Boseok;Kim, Jae Ho;Liu, Guoxu;Jang, Eun Sung
    • The Journal of the Korea Contents Association
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    • v.17 no.10
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    • pp.567-575
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    • 2017
  • In this study, when diagnosis pancreatic cancer by dual time point PET/CT, we propose SUVm 2.52 as the threshold value for performing the dual time point PET/CT exam. The hypothesis of normal distribution was adopted through data conversion of 60 pancreatic diseases. The proposed SUVm2.52 boundary value showed a significance level that could be applied to both 120 and 180 minutes of delay time scan for pancreatic cancer determination (p<0.05). C-value variation shows that delay time 2 hour test is more useful than delay time 3 hour test. When the SUVm 2.52 is set to the boundary value and the double-time point PET/CT exam is performed, the probability of distinguishing cancer from inflammation in the delayed image is 95%. When the delayed test is performed with the proposed boundary value SUVm 2.52, Compared with general PET / CT scans, it is thought that it may be helpful to distinguish pancreatic cancer.

Performance of Broiler Chicks Fed Normal and Low Viscosity Rye or Barley with or without Enzyme Supplementation

  • He, T.;Thacker, P.A.;McLeod, J.G.;Campbell, G.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.2
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    • pp.234-238
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    • 2003
  • This experiment was conducted to measure nutrient digestibility and performance in broiler chicks fed diets based on normal and low viscosity rye or barley fed with and without enzyme (pentosanase and $\beta$-glucanase) during a 17 day growth trial. A total of 150 one-day old, male broiler chicks (5 birds per pen and 5 pens per treatment) were randomly assigned to one of six dietary treatments in a $3{\times}3$ factorial design experiment (3 cereals${\times}$2 enzyme levels). Digestibility coefficients were determined using chromic oxide. Digestibility coefficients for dry matter and crude protein were significantly (p=0.0001) higher for the barley-based diets than for any of the rye-based diets. Digestibility coefficients for gross energy did not differ (p>0.05) due to cereal grain. There were no differences in the digestibility coefficients for dry matter and gross energy between chicks fed normal and low viscosity rye. However, the digestibility coefficient for crude protein was higher (p=0.01) for the low viscosity rye compared with the normal viscosity rye. Addition of enzyme to the diet significantly (p=0.0001) increased digestibility coefficients for dry matter, crude protein and energy. There were no significant differences in weight gain, feed intake or feed conversion between birds fed barley or rye or between birds fed normal or low viscosity rye. Enzyme supplementation significantly improved (p=0.0001) weight gain, intake and feed conversion. The overall results of this experiment indicate that unsupplemented barley and rye do not support adequate growth rates in poultry. Enzyme supplementation dramatically improved broiler performance. In addition, genetic selection to reduce the viscosity of rye had only a modest effect on the nutritive value of rye for broilers.

Expression of Tiam1 in Lung Cancer and its Clinical Significance

  • Wang, Hong-Ming;Wang, Jing
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.613-615
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    • 2012
  • The aim of this study was to ana1yze T-cell lymphoma invasion and metastasis-inducing factor 1 (Tiam1) expression in 1ung cancer patients. A total of 204 patients with lung cancer tissue lesions were enrolled in the present study, along with 40 cases of normal lung tissue and 40 of normal fetal lung tissue. Tiam1 protein expression level was determined using intensity quantitative analysis, for comparison in lung cancer, metastatic, normal lung, and fetal lung tissue. The positive unit (PU) of Tiam1 was $13.5{\pm}5.42$ in lung cancer,$5.67{\pm}1.56$ in norma1 epithelial cells, and $5.89{\pm}1.45$ in fetal lung epithelial cells. The value in the lung cancer tissue was significantly higher than that in the normal lung tissue and the fetal lung tissue (P<0.01). The Tiam1 PU values with lymph node metastasis and without 1ymph node metastasis were $15.2{\pm}4.34$ and $12.5{\pm}4.23$, respectively, and the difference was statistically significant (P<0.05). The Tiam1 PU values in different tumor, nodes, metastasis (TNM) stages, III-IV period, and I-II phase were $14.7{\pm}4.14$ and $11.0{\pm}5.34$ (P<0.05). A correlation was found between Tiam1 expression and the age of patient, tumor size, tumor type, and tumor differentiation. Tiam1 protein expression in the lung tumor tissue is significantly higher than that in the normal lung tissue and fetal lung tissue. Tiam1 expression may be closely related to lung cancer development and metastasis.

Paleomagnetic Study on the Volcanic and Sedimentary Rocks of Jeju Island (제주도(濟州道)에 분포(分布)하는 화산암류(火山岩類) 및 퇴적암류(堆積岩類)에 대(對)한 고지자기(高地磁氣) 연구(硏究))

  • Min, Kyung Duck;Won, Joong Sun;Hwang, Suk Yeon
    • Economic and Environmental Geology
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    • v.19 no.2
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    • pp.153-163
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    • 1986
  • Paleomagnetic and geological studies of volcanic and sedimentary rocks of Jeju Island have been carried out to determine the position of virtual geomagnetic pole(VGP), and to estimate the geological sequence and their age. As a result of paleomagnetic studies, the reversal polarities are measured in the Sanbangsan trachyte and Hwasun formation, and the normal are the rest. In case of normal polarity, the mean values of declination and inclination are $2.3^{\circ}$ and $48.4^{\circ}$, respectively, and the average value of VGP is $85.4^{\circ}N$ and $79.9^{\circ}W$. The locations of VGP's are coincident with those obtained from world-wide Plio-Pleistocene rocks. The Hwasun formation and Seongsan formation which have been known to be sedimented in the similar time in the 2nd-stage of volcanic eruption, possess reversal and normal polarities, respectively. This fact brings about the result that two formations should be separated in a sense of geological sequence. Consequently, the geological sequence of the 2nd-stage of volcanic eruption is Pyoseonri basalt-Seoguipo hawaiite-Hwasun formation-Seongsan formation-Jungmun hawaiite-Sanbangsan trachyte. Referring to the paleomagnetic studies and the previous and present geological studies, Seoguipo formation corresponds to the Gauss normal epoch, the 2nd-stage of volcanic eruption to Matuyama reversed epoch, and the 3rd-, 4th-, and 5th-stages to Brunhes normal epoch. Therefore, the Seoguipo formation is mostly sedimented during late Pliocene and/or presumably extended to the early Pleistocene. The rocks of the 2nd- to 5th-stage are formed later than this.

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The comparison in daily intake of nutrients, dietary habits and body composition of female college students by body mass index

  • Ko, Myung-Soo
    • Nutrition Research and Practice
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    • v.1 no.2
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    • pp.131-142
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    • 2007
  • The purpose of this study was to investigate differences in the body composition, dietary habits, daily intake of nutrients and clinical blood indices in female college students by body mass index of normal weight, overweight and obese. The subjects of this research were 141 respondents of a survey carried out on students, and subjects were given 60 minutes to answer questionnaires, by recording their own answers. The average heights and weights of subjects by BMI were 162.17 cm, 52.73 kg in normal weight group, 162.35 cm, 62.22 kg in overweight group and 161.72 cm, 69.82 kg in obesity group, respectively. As for the survey daily of meals, starving breakfast and kind of snacks of subjects were significantly different among the groups by BMI. In animal protein food intakes, meat intake was the highest 'every day' food consumed by subjects, and there was a significant difference in distribution of BMI among subjects. Fruits, and greenish and yellow vegetables intakes were the highest 'every day' foods indicated by the normal weight group. Consumption of carbonated beverages and juices showed a significant difference among groups by BMI. The average of total-cholesterol was the overweight group was the higher value. There was a significant difference in diastolic blood pressure and systolic blood pressure among the groups by BMI. Average daily calories intake levels were insufficient and the intake ratio of carbohydrates, protein, and fat was the normal weight group 68 : 17 : 15, the overweight group 64 : 18 : 18 and the obese group 73 : 14 : 13. Results of the daily vitamin intake analyses displayed riboflavin, niacin, vitamin C, and folic acid levels lower than the RI levels. Fe intake was the normal weight group 81%, overweight group 76%, obese group 59% of the RI level. Therefore, it is necessary for college students to establish regular meals, good quality snacks and consuming more vitamin and mineral nutritions for optimal health conditions.

THE MRI-BASED COMPARISON OF NORMAL- AND ABNORMAL-SIDE RETRODISCAL TISSUE, AND RELATIONSHIP BETWEEN CLINICAL EXAMINATION & THE MRI FINDINGS OF RETRODISCAL TISSUE IN PATIENTS WITH UNILATERAL TMJ INTERNAL DERANGEMENT (편측 악관절 내장증 환자에서 비이환측과 이환측의 자기공명영상 소견상 원판후 조직의 비교 및 임상소견과의 관계)

  • Yoon, Hyun-Joong;Park, Chul-Hong;Kim, Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.4
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    • pp.330-335
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    • 2002
  • The study was performed to investigate the comparison of relative signal intensity of normal- and abnormal-side retrodiscal tissue, and relationship between clinical examination, joint effusion and relative signal intensity of retrodiscal tissue in patients with unilateral TMJ internal derangement. The study group comprised 19 females and 9 males, with a mean age of 29 years. After measurements of the signal intensity were made on the MR imager for the T2 weighted images on retrodiscal tissue and brain gray matter, we calculated relative value and tried to find relationship between clinical examination, joint effusion and relative signal intensity on normal- and abnormal-side. The results are as follows. 1. The gray matter is an appropriate reference point. 2. The relative signal intensity is high significantly in abnormal-side retrodiscal tissue compared with normal-side retrodiscal tissue. 3. The relative signal intensity is high significantly in painful joints compared with nonpainful joints and in joints with joint effusion compared with joints without joint effusion. 4. The relative signal intensity in normal joints, joints with reduction and joints without reduction is increased in order significantly.

Dietary Intake Pattern of the Korean Adult Population by Weight Status - 2001 National Health and Nutrition Survey - (우리나라 성인의 체중상태에 따른 식생활 특성 - 2001 국민건강.영양조사 결과에 근거하여 -)

  • Lee Yoon-Na;Lee Haeng-Shin;Jang Young-Ai;Lee Hae-Jeung;Kim Bok-Hee;Kim Cho-Il
    • Korean Journal of Community Nutrition
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    • v.11 no.3
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    • pp.317-326
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    • 2006
  • To explore the relationship between weight status and food intake pattern, the Nutrition Survey results of the 2001 National Health and Nutrition Survey were analyzed. Dietary intake data of Korean adults aged 20 to 64. years who participated in the 2001 National Health and Nutrition Survey, was used along with their demographic data. Subjects were classified into 4 groups based on the BMI value of subjects: underweight, normal, overweight and obese. For male adults, obese subjects had significantly higher mean intake of energy, protein, carbohydrates, and fat than normal subjects. In addition, obese male adults consumed more animal foods, especially more meats, than normal subjects. However, females obese subjects did not show higher intake of energy or fat. Although obese male adults showed higher energy intake, calcium and iron intake per 1000 kcal was lower than normal adults. Average calcium intake in females was low; about 70% of RDA regardless of obesity level. In addition, riboflavin and Vitamin A intake was lower in overweight and obese female than in normal females. Percentage of subjects with low fruit and vegetable intake (< 400 g per day) was also high in female subjects. These results showed that food and nutrient intake patterns of obese population were different between male and female adults. These dietary intake patterns need to be considered in developing and implementing nutrition policy and intervention programs to prevent and control obesity. Moreover, the National Survey and monitoring system should be developed for continuous and effective investigation on the relationship between obesity and dietary intake.

The Histological Change of Orbicularis Oculi Muscle according to the Age (나이에 따른 안륜근의 조직학적 변화)

  • Ahn, Ki Young;Chang, Jae Hoon;Choi, Won Seok;Shin, Im Hee;Park, Jae Bok
    • Archives of Plastic Surgery
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    • v.33 no.1
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    • pp.87-94
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    • 2006
  • This study is to investigate the patients who had blepharoplasty for cosmetic purposes or facial nerve disorders. 21 patients were examined with an age from 17 to 63 years. Sixteen cases were classified as a normal group for investigation of the histopathologic change according to the age. The rest were patients of Bell's palsy(2), $Botox^{(R)}$ injection(2) and blepharospasm (1). We measured a mean diameter of myofiber and dimension's proportion of muscluar tissue per regular visual field. First, we measured a statistical significance according to the age in normal cases by grouping them into younger than 30-year-old, 30's, 40's, 50's and 60's. Second, we divided normal cases(16) into Group A and B by two bases for statistical analysis. In conclusion, although there were several differences as vacuolation, internalization of sarcolemnic nuclei between 35-year-old and 62-year-old patients in simple comparison, there was no uniform decrease according to the age. There were also no significant statistical changes in the value of a diameter of myofibers and dimension's proportion of muscular tissue according to the age in any of the two normal groups. But in $Botox^{(R)}$ injection and Bell's palsy, blepharospasm patients, two values showed remarkable difference compared to the normal group of same age.

Estimating the CoVaR for Korean Banking Industry (한국 은행산업의 CoVaR 추정)

  • Choi, Pilsun;Min, Insik
    • KDI Journal of Economic Policy
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    • v.32 no.3
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    • pp.71-99
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    • 2010
  • The concept of CoVaR introduced by Adrian and Brunnermeier (2009) is a useful tool to measure the risk spillover effect. It can capture the risk contribution of each institution to overall systemic risk. While Adrian and Brunnermeier rely on the quantile regression method in the estimation of CoVaR, we propose a new estimation method using parametric distribution functions such as bivariate normal and $S_U$-normal distribution functions. Based on our estimates of CoVaR for Korean banking industry, we investigate the practical usefulness of CoVaR for a systemic risk measure, and compare the estimation performance of each model. Empirical results show that bank makes a positive contribution to system risk. We also find that quantile regression and normal distribution models tend to considerably underestimate the CoVaR (in absolute value) compared to $S_U$-normal distribution model, and this underestimation becomes serious when the crisis in a financial system is assumed.

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Effect of Jojoongikgi-tang on the Purpura Induced by DNCB (조중익기탕(調中益氣湯)이 DNCB로 유발(誘發)시킨 생쥐의 자반(紫斑)에 미치는 영향(影響))

  • Kim, Hee-Chul;Kim, Jung-Sang;Choi, Chang-Won
    • The Journal of Korean Medicine
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    • v.20 no.3 s.39
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    • pp.27-35
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    • 1999
  • The purpose of this study was to investigate the histochemical effect of Jojoongikgi-tang (JIT) on hairless mice induced by DNCB. For the study, DNCB was applied on the infrascapular region of the mices skin and then JIT was orally administered. As a result, the following histochemical changes of the dermis were observed through light and electron microscopes, and statistical data. The results obtained were as follows: 1. In the 2 days experimental group, more histamine mast cells dermis occurred than in the control or normal group when observed under light microscope. When an electron microscope was used, histochemical reactive cells in the dermis were found as mast cells that contained more cytoplasmic granules than in the control or normal group. 2. In the 5 days experimental group, the number of mast cells were decreased over the control or normal group when observed under light microscope. When an electron microscope was used, mast cells in the control contained secretory granules with higher electron density than those of the experimental group. 3. As a result of statistical analysis, the mean value of mast cells in the normal 2 days control and experimental groups was not significantly different (p<0.05). 4. However, the mean values of it in the normal ($19.1000{\pm}6.3154$), 5 day control ($103.4500{\pm}42.2704$) and 5 day experimental groups ($35.9500{\pm}8.5746$) were significantly different (p<0.05). From the above results, it is concluded that JIT is efficient against the purpura induced by DNCB.

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