• Journal of Pharmacopuncture
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• v.7 no.1 s.12
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• pp.37-51
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• 2004

Objective : Recently scolopendrid aqua-acupuncture has been a good effect on pain control but it has not been known about clinical safety. The purpose of this study was to investigate acute toxicity of scolopendrid aqua-acupuncture. Method : In order to prove the clinical safety of scolopendrid aqua-acupuncture, We have observed a bacteriological examination and clinical pathology test after scolopendrid aqua-acupuncture treatment. Balb/c mice were injected intravenous with Scolopendrid aquaacupuncture treatment for $LD_{50}$ and acute toxicity test. We analyzed physical reaction(side effect)and clinical pathology test before and after Scolopendrid aqua-acupuncture treatment of mice and 20 patients suffering from pain, who admitted department of Acupunture and Moxibustion, College of Oriental Medicine, Won-Kwang University Kwangju hospital. Results : In the Blood agar plate and Nutrient agar plate, a bacteriological examination did not show a bacillus. In acute $LD_{50}$ toxicity test, there was no mortality thus unable to attain the value. Examining the toxic response in the acute toxicity test, there was no sign of toxication. In acute toxic test, running biochemical serum test couldn't yield any differences between the control and experiment groups. In the 20 patients treated with Scolopendrid aqua-acupuncture, hematologic test did not show remarkable change. In the 20 patients treated with Scolopendrid aqua-acupuncture, Liver function test(AST, ALT, ALP) showed a slight decrease on the contrary, and abnormal rate showed a decrease of 5.0% compared with previous study. Reanl function test(BUN, Cr) and abnormal rate showed a decrease of 5.0% compared with previous study. In the 20 patients treated with Scolopendrid aqua-acupuncture, Electrolyte were normal range before and after treatment. In the Urine analysis of 20 patients, Leukocyte, Protein, Glucose, Keton, Bilirubin, U-bilinogen were not detected before and after Scolopendrid aqua-acupuncture treatment, and the rest almost made no difference.

• The Journal of Engineering Geology
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• v.12 no.4
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• pp.421-437
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• 2002

In order to quantify the anisotropic properties of rock included joints and shear behavior in joint surface, the mold is Produced for rock joint surface using gypsum Plaster and Peformed for replicated joint models made of cement mortar. Rock sample is measured using mechanical profilometer before testing and their result is expressed quantitatively. The statistical parameters and the fractal dimension by fractal theory for roughness is investigated its coordinate value for numerical process. The shear strength to the shear displacement in low level normal stress ismaintained or increased in most joint models. Their results present that this relationship is depended several roughness properties in joint model for natural rock joint. The relationship between the shear strength and the Properties for profiles estimated by some statistical parameter in roughness has the low correlation and is not constant. The result between the data for direct shear test and using Barton's equation, Barton's equation has not the effectiveness for the effect of anisotropy and has not suitable to recognizing the properties for joint surface. It means that JRC has not the properties of anisotropic rock surface. The fractal dimension is well correlated with the data of direct shear test than those of JRC. New experimental formulae using fractal dimension is comported with the anisotropic properties for direct shear test.

• Korean Journal of Environmental Biology
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• v.31 no.4
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• pp.370-375
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• 2013

Exotic species in aquatic ecosystem generate various problems domestically as well as globally. Largemouth bass (Micropterus salmoides) which is a well-known exotic species globally, acts as a substantial disturbance factor on the native fish communities in Korea due to the high predation pressure and hence designated as a ecologically harmful species by Ministry of Environment. In this study, we investigated the impact of largemouth bass on Korean native fish population, crucian carp (Carassius auratus), to identify responses of the prey fish. Two fish species were collected at seven reservoirs distributed at the Nakdong River catchment area, and changes in length-frequency and length-weight relationship (LWR) were analysed depending on existence of large-mouth bass. At bass absent sites, ratio of under age 1 year individuals were small, and over age two years were dominant. Conversely, normal length-frequency distribution pattern was identified at bass absent sites. The LWR of crucian carp (fish smaller than total length of 160 mm were only considered as it is frequently consumed by bass predation) was different depending upon bass existence. The value of parameter b at bass absent reservoirs was 2.909, which was smaller than that of bass present reservoirs, 3.100. Our results imply that crucian carp at bass present reservoirs presented a different strategy to survive from predation by bass, through relatively rapid growth. We propose that other native species might have similar growth strategies like crucian carp.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.10
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• pp.2503-2508
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• 2014

This study is about the selection and noise test of electronic sensor which is preceded by electric Operating Cell(EOC) development using electronic sensor technology to solve the structural weakness of Mechanism Operated Cell(MOC) in VCB, and has a final target in product development minimizing contact malfunction of the chattering or rebounce states caused by existing MOC. In this test results, when opening and closing VCB, rising velocity of surge voltage in opening time was measured 4.2 times faster than closing time and noise decibel value was measured respectively 120dB and 110dB. When supplying 60kV power frequency overvoltage, we found that sensor output graph in VCB opening and closing times operated stably without distortion. When supplying 150kV $1.2{\times}50{\mu}s$ impulse frequency voltage, we found that voltage graph of output contact in sensor opening and closing sides maintained a normal condition without distortion, and when supplying 2500A current, we found that tested result of electric field noise operated stably without distortion.

• Communications for Statistical Applications and Methods
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• v.17 no.3
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• pp.459-471
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• 2010

Higher quality level is generally perceived by customers as improved performance by assigning a correspondingly higher satisfaction score. Usually, the quality level is measured by process capability indices. The index is used to determine whether a production process is capable of producing items within a specified tolerance. The third generation index $C_{pmk}$ is more powerful than two useful indices $C_p$ and $C_{pk}$. which have been widely used in six sigma industries to assess process performance. Most evaluations on process capability indices focus on point estimates, which may result in unreliable assessments of process performance. In this paper, we consider better testing procedure on assessing process capability index $C_{pmk}$ for practitioners to use in determining whether a given process is capable. It is easy to use the proposed method for assessing process capability index $C_{pmk}$. Whether a process is clearly normal or nonnormal, our bootstrap testing procedure could be applied effectively without the complexity of calculation. A numerical result based on our proposed method is illustrated.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.2
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• pp.43-65
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• 2012

Objectives: This study was designed to investigate the effects of Hyeolbuchukeotang( HCT) on the Estradiol Valerate(EV) induced Polycystic Ovaries and the Implantation of rats. Methods: PCO was induced by single intramuscular(IM) injection with EV in female rats. Normal group(n=8) were injected with sesame oil and orally administrated distilled water for 60 days. Control group(n=8) were injected with EV and orally administrated distilled water for 60 days. HCT treated group(n=8) were injected with EV and orally administrated HCT for 60 days. At the end day of experiment, we measured weights of body, ovaries, adrenal glands, uterus and contents of serum LH, FSH, ADD. The histomorphometrical changes of ovaries were also evaluated. And we observed the NGF and CRF expression by immunohistochemistry. Also we observed the mating and count the number of implantation. Results: - The weights(mg) of ovaries in HCT treated group($58.9{\pm}6.5$) were significantly increased (p<0.01) compared with control group ($42.3{\pm}8.5$). - The number of mature follicles in HCT treated group($9.8{\pm}2.6$) was significantly increased (p<0.01) compared with control group($6.1{\pm}2.1$). - The number of cystic follicles in HCT treated group($1.6{\pm}1.2$) was significantly decreased (p<0.01) compared with control group($3.8{\pm}1.5$). - The value of serum FSH(mIU/ml) in HCT treated group($3.870{\pm}2.151$) was significantly decreased(p<0.05) compared with control group($10.476{\pm}6.294$). - The expression of NGF-immunoreactive cells in the ovarian cells in HCT treated group was lesser observed than control group. - The number of implantation in HCT treated group($7.4{\pm}1.8$) was significantly increased (p<0.05) compared with control group($3.1{\pm}4.4$). Conclusions: Hyeolbuchukeo-tang(HCT) is effect on polycystic ovaries and the implantation of rats by EV-induced.

• International Journal of Highway Engineering
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• v.4 no.4 s.14
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• pp.23-39
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• 2002

This study dealt with developing a new approach for finding properties which might represent rut resistance characteristics of asphalt mixture under static loading. Two aggregates, a normal asphalt (pen 60-80) and 5 polymer-modified asphalts were used in preparation of 12 dense-graded mixtures. Marshall mix design was used in determination of OAC and each mixture at the OAC was prepared for a newly-developed Kim test on Marshall specimen (S=10cm) and gyratory specimen (S=15cm), and for wheel tracking test. Kim test used Marshall loading frame and specimens were conditioned for 30min at $60^{\circ}C$ before loading through Kim tester an apparatus consisting of a loading column and a specimen and column holder Diameter (D) of column was 3cm and 4cm with each column having different radius (r) of round cut at the bottom. The static load was applied at 50mm/min in axial direction of the specimen, not in diametral direction. The maximum load ($P_{max}$) and vertical deformation (y) at $P_{max}$ point were obtained from the test. A strength value was calculated based on the $P_{max}$ r, D and y by using the equation $K_D = 4P_{max}/{\pi}(D-2(r-\sqrt{2ry-y^2}))^2$ and is defined as the deformation strength ($kgf/cm^2$). The values of $P_{max}$/y and $K_I=K_D/y$ were also calculated. In general the leading column diameter and radius of round cut were significant factors affecting $K_D$ and $P_{max}$ values while specimen diameter was not. The statistical analyses showed the $K_D$ had the best correlation with rut depth and dynamic stability. The next best correlation was found from $P_{max}$ which was followed by $P_{max}$/y and $K_I$ in order.

• Tunnel and Underground Space
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• v.16 no.3 s.62
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• pp.259-276
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• 2006

In rock mass subject to high in-situ stresses, the failure process of rock is dominated by the stress-induced fractures growing parallel to the excavation boundary. When the ratio of in situ stresses compared to rock strength is greater than a certain value, progressive brittle failure which is characterized by popping and spatting of rock debris occurs due to stress concentration. Traditional constitutive model like Mohr-Coulomb usually assume that the normal stress dependent frictional strength component and the cohesion strength component are constant, therefore modelling progressive brittle failure will be very difficult. In this study, a series of numerical analyses were conducted for surrounding rock mass near crude oil storage cavern using CW-FS model which was known to be efficient for modelling brittle failure and the results were compared with those of linear Mohr-Coulomb model. Further analyses were performed by varying plastic shear strain limits on cohesion and internal friction angle to find the proper values which yield the matching result with the observed failure in the oil storage caverns. The obtained results showed that CW-FS model could be a proper method to characterize essential behavior of progressive brittle failure in competent rock mass.

• Journal of Chest Surgery
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• v.16 no.3
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• pp.281-288
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• 1983

Heparinization is an essential step in extracorporeal circulation for open heart surgery. But wide individual variation to heparin effect sometimes makes it difficult to anticoagulate safely or neutralize appropriately. Because the conventional set protocol of heparinization did not consider this individual variation, a new method of control of heparinization was proposed by Dr. Brian Bull in 1974. We compared the group in which a conventional set protocol was used [Control group] with the other in which a new protocol modified from that of Bull was used [ACT group], on the aspects of the dosages of heparin and protamine administered and postoperative bleeding. Our conventional protocol [Control group] consisted of: 1. Initial heparin was given at dose of 350U/Kg into the right atrium prior to bypass. 2. Additional heparin was given every hour during E.C.C., as much as a half of the Initial dose. 3. 600U of heparin was mixed into every 100ml. of priming solution. 4. The protamine dose was calculated by totalling the units of heparin given to the patient and giving 1 .8mg. of protamine per 100 units of heparin. ACT protocol [ACT group] consisted of: 1. Initial heparinization was same as that of conventional protocol. 2. ACT`s were checked before [A point] and 10 minutes after initial heparinization [B point]. With these 2 points, a dose response curve was drawn. 3. Heparin for the priming solution was same as in control group. 4. Every 30 minutes during E.C.C., ACT`s were checked with Hemochron [International Technidyne Corp.]. ACT between 450 and 600 seconds was regarded as safety zone. If ACT checked at a time was below 450 seconds, heparin dose was calculated on the dose-response curve to lengthen ACT to 480 seconds and was given into the oxygenator. 5. About 10 minutes before the term of E.C.C., ACT was checked to estimate the blood heparin level at the time. Then, protamine dose was calculated at dose of 1.Stag per 100 units of heparin. The calculated dose of protamine was mixed into 50 to lO0ml of 5% Dextrose Water and dripped intravenously during the period of 15 minutes. Compared these two groups mentioned above, results were obtained as follows: 1. Mean value of normal ACT checked with Hemochron on 30 preoperative patients was 124 seconds [range 95-145 sec.]. 2. Doses of heparin and protamine given to the patient were decreased in ACT group as much as 32.2% and 62.2% respectively. 3. Postoperative bleeding and transfusion were also decreased in ACT group in 60.5% and 67.1% respectively. 4. Our modified dose-response curve did not cause any problems in the control of heparinization. 5. Initial heparinization [Heparin 350U/Kg] was sufficient for the most patients until 60 minutes under extracorporeal circulation. 6. We used 1.5mg of protamine to neutralize 100 units of heparin. But smaller dose of protamine may be sufficient for appropriate neutralization.

• Journal of Korean Society of Transportation
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• v.31 no.5
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• pp.71-78
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• 2013

This paper investigated the influences of ramp traffic flow on the lane utilization for signalized intersection approaches which are adjacent to an off-ramp-street junction. The statistical test showed a correlation between lane utilization and the ramp traffic flow. As the ramp traffic flow increases, the left lanes are less utilized and the right lanes are more utilized. The lane utilization factors are calculated by applying traffic data collected from the Seoul Metropolitan area. The utilization factors are 1.113 for 2 lanes, 1.124 for 3 lanes, and 1.131 for 4 lanes. The lane utilization factors proposed in the paper show higher values than those in current Korea Highway Capacity Manual (KHCM) under the conditions that the number of lanes is 2 or 3. However, the lane utilization factor for 4 lanes in the paper shows lower value than in KHCM. The ramp traffic flow causes more utilization of the right lanes than at normal signalized intersections and the extent gets larger as the number of lanes decreases. Based on the results of the paper, the lane utilization factors at signalized intersection approaches should be revised and reasonable capacity should be recalculated if the signalized intersection is adjacent to an off-ramp-street junction.