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검색결과 61건 처리시간 0.028초

The effects of aqua-exercise on the muscle atrophy of hind limb in rats

  • Cho sun-yeo
    • The Journal of Korean Physical Therapy
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    • 제14권3호
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    • pp.373-406
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    • 2002
  • This study was peformed to investigate the effects on skeletal muscle recovery with aqua-exercise; swimming to take the muscle endurance for 20 days on two group of white rats which were the low extremity atrophy group(control groups) by fixed for two weeks and aqua-exercise group(experimental groups) after it. The effects was observed with light and electron microcope to measure the morphological changes of muscle fibers. The results obtained were as follow. 1. Light microscope: In the case of control groups, quadriceps fibers had been irregular alignment, decreased muscle width and the irregular alignment nuclear appeared, as it is degenerative muscle fibers. In the case of experimental groups, the fibers had been regular alignment cells and fibers. The nucleus of muscle had been normal characterized by oval shape and fiber sarcomere clearly classified. 2. Electron microscope: In the case of control groups, there were the quadriceps which was Z-line streaming phenomenon induced at the sarcomere and cells nuclear separated from basal membrane. It was not only observed the sarcomere alignment irregularly and mitochondria damaged, but also vacuoles found. In the case of experimental groups, A band, I band, H band had been clearly appeared, classified at the myofibrils of quadriceps, and electronic dense M-line found in sarcomere. There were observed satellite cells and basal laminas that usually to be appeared at the time of mitochondrial development, skeletal muscle fiber regeneration or development. This results suggest that the aqua-exercise assisted to inhibit the degenerative morphological changes of skeletal muscle cells and help to recover from abnormal states. Especially, it is considered to effect on a normal structural formation.

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구형정자의 난자내 미세주입 후 보조활성화술에 의한 임신과 분만 1례 (A Normal Pregnancy and Delivery by Assisted Activation Following Roundheaded Spermatozoa (Globozoospermia) Injected into Oocytcs)

  • 주재홍;이용찬;윤산현;임진호;박흠대
    • Clinical and Experimental Reproductive Medicine
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    • 제27권3호
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    • pp.301-305
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    • 2000
  • Globozoospermia is a rare type of teratozoospermia. It occurs in 0.1% of all andrological patient's and used to be considered sterile. Globozoospermic patient has 100% round headed spermatozoa, but the spermiogram is normal. The spermatozoa show oval-shape head, the lack of a nuclear envelope, acrosome, and post acrosomal sheath. Objective: To report that a couple with infertility secondary to globozoospermia received ICSI treatment. Material and Method: Case report Results: In the first trial, fertilization was failed. In the second trial, 40% of oocytes were fertilized and all of these embryos were cleaved, but pregnancy did not achieved. In the third trial, sperm injected oocytes were exposed to 10 ${\mu}M$ calcium ionophore for 15 min. All of the injected oocytes were fertilized and proceeded to develop. Triplet pregnancy was achieved after the transfer of six embryos in their third cycle. One embryo vanished and the remaining twins (female) were delivered at 33 weeks of gestation by Caesarean section. Conclusion: This result shows that assisted activation following ICSI may overcome infertility associated with globozoospermia.

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노르스름한 성대점막 색변화를 보이는 편평 성대 낭종: 개방형 성대 낭종 (An Yellowish Flat Intracordal Cyst : Open Cyst)

  • 김지훈;이은정;김연희;홍현준;최홍식
    • 대한후두음성언어의학회지
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    • 제23권1호
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    • pp.52-55
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    • 2012
  • Background and Objectives : Based on histological findings, intracordal cysts are divided in two subtypes : retention cysts and epidermoid cysts. They are typically located in the superficial layer of the lamina propria and appeared as opaque ovoid buldging masses underlying the epithelium. They are characterized by unilateral diminished mucosal wave on stroboscopy. In this article, we report some cases of patients with an oval shaped-yellowish flat cyst. Materials and Method : At the clinic of the department of otorhinolaryngology in Gangnam Severance Hospital, with 3 female complained of hoarseness as subjects, using the stroboscopy we checked preoperative and postoperative vocal cord and operative findings. Surgery was performed under general anesthesia by the senior authors. All patients noted subjectively that their performing voice was improved. Results : During surgery, an oval shaped-yellowish flat cystic lesion was distinguished from normal epithelium. On palpation of this area with microforceps and cottons, the yellowish discharge was noted to move out from the opening of the cyst. In one case, the cyst was ruptured but remove the capsule completely. In other cases, sulcus was noted at the oppsite site. Conclusion : Because of the opening, the cyst was not easy to dissect and remove completely. After the debris was move out, fibrosis around the opening and invaginated epithelium extending into the deeper layers to the fold. The cyst was must removed carefully and completely for improvement of voice quality before evolving into a sulcus vocalis.

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Fertilization and embryo quality of mature oocytes with specific morphological abnormalities

  • Yu, Eun Jeong;Ahn, Hyojeong;Lee, Jang Mi;Jee, Byung Chul;Kim, Seok Hyun
    • Clinical and Experimental Reproductive Medicine
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    • 제42권4호
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    • pp.156-162
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    • 2015
  • Objective: To investigate fertilization and embryo quality of dysmorphic mature oocytes with specific morphological abnormalities obtained from intracytoplasmic sperm injection (ICSI). Methods: The fertilization rate (FR) and embryo quality were compared among 58 dysmorphic and 42 normal form oocytes (control 1) obtained from 35 consecutive ICSI cycles, each of which yielded at least one dysmorphic mature oocyte, performed over a period of 5 years. The FR and embryo quality of 441 normal form oocytes from another 119 ICSI cycles that did not involve dysmorphic oocytes served as control 2. Dysmorphic oocytes were classified as having a dark cytoplasm, cytoplasmic granularity, cytoplasmic vacuoles, refractile bodies in the cytoplasm, smooth endoplasmic reticulum in the cytoplasm, an oval shape, an abnormal zona pellucida, a large perivitelline space, debris in the perivitelline space, or an abnormal polar body (PB). Results: The overall FR was significantly lower in dysmorphic oocytes than in normal form oocytes in both the control 1 and control 2 groups. However, embryo quality in the dysmorphic oocyte group and the normal form oocyte groups at day 3 was similar. The FR and embryo quality were similar in the oocyte groups with a single abnormality and multiple abnormalities. Specific abnormalities related with a higher percentage of top-quality embryos were dark cytoplasm (66.7%), abnormal PB (50%), and cytoplasmic vacuoles (25%). Conclusion: The fertilization potential of dysmorphic oocytes in our study was lower, but their subsequent embryonic development and embryo quality was relatively good. We were able to define several specific abnormalities related with good or poor embryo quality.

Testosterone Propionate 투여로 인한 생쥐 고환(睾丸) Leydig Cell의 형태학적변화(形態學的變化)에 대한 전자현미경적연구(電子顯微鏡的硏究) (Electron Microscopic Studies on Testicular Leydig Cells of Mice Administered with Testosterone Propionate)

  • 이재현;이차수
    • 대한수의학회지
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    • 제15권2호
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    • pp.241-250
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    • 1975
  • The light and electron microscopic observations were carried out in order to know the morphological changes of the testicular Leydig cells in the mouse injected with testosterone propionate for a long period. The results obtained were as follows: With the light microscopic study, atrophy of the Leydig cells and larger sudanophilic lipid granules in the experimental group than normal were observed. 2. By the electron microscopic finding, the small spherical or oval mitochondria, large lipid droplets, a decrease in number of smooth endoplasmic reticutum and distended saccular or vacuolar smooth endoplasmic reticulum were observed in the experimental group. Membranous whorls with droplet increased in number and size in the experimental group.

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폐에 전이된 점액표피양 암종의 세포병리학적 소견 (Cytopathology of Metastatic Mucoepidermoid Carcioma of the Lung)

  • 박원서;함의근
    • 대한세포병리학회지
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    • 제5권2호
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    • pp.180-183
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    • 1994
  • A case of metastatic mucoepidermoid carcinoma of the lung, originating from the hard palate, was diagnosed by sputum and bronchial washing cytology. Although the cytologic features of mucoepidermoid carcinoma have been well described, it is easy to confuse mucoepidermoid carcinoma with the more common primary adenocarcinoma or squamous cell carcinoma of the lung. The features distinguishing mucoepidermoid carcinoma from other primary neoplasms include 1) mucus-secreting cells individually and in clusters admixed with other cell components, 2) epidermoid cells identified by the presence of abundant spread-out cytoplasm and an oval dark nucleus and 3) intermediate cells resembling normal ductal epithelial cells with moderate-to-scanty cytoplasm, a central, round vesicular nucleus and a prominent nucleolus. The morphologic features of metastatic mucoepidermoid carcinoma in this case were similar to those of primary salivary mucoepidermoid carcinoma.

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Primary pulmonary adenocarcinoma metastasized to kidney in a captive nutria (Myocastor coypus)

  • Oh, Yeonsu;Cho, Ho-Seong
    • 한국동물위생학회지
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    • 제40권2호
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    • pp.139-142
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    • 2017
  • A six-year-old male captive nutria (Myocastor coypus) maintained in a closed space with a small vent was found dead in his cage. Gross findings showed multifocal nodules in varying sizes, small 0.5 to large 5 cm in diameter, intermixed with normal parenchyma were scattered all over the surface of the lungs and a kidney, which the cut surface was smooth, compact and whitish in color. Microscopically, small round to oval neoplastic cells with modest to slight amounts of cytoplasm formed acinar and gland-like structures. Immunohistochemically, cells were strongly positive for E-cadherin and slightly reactive for thyroid transcription factor-1 (TTF-1). Based on those diagnostic features, the neoplasia was diagnosed as primary pulmonary adenocarcinoma (small cell type) and metastasized into the kidney. This is the first case report of malignant pulmonary tumor and its metastasis in the nutria.

청년들의 얼굴형태와 안경착용에 관한 연구 (A Study on Face Types and Glasses Wear of Young Peoples)

  • 김혜동;김현정
    • 한국안광학회지
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    • 제12권3호
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    • pp.35-38
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    • 2007
  • 만 20세에서 30세 사이의 남녀 100명을 대상으로 눈 크기를 측정하였고, 얼굴형과 안경착용에 관한 연구를 한 결과 다음과 같은 결론을 얻었다. 1. 전체적인 눈의 가로 크기는 2.4 mm 2명 이하(2%), 2.5-2.9 mm 40명(40%), 3.0-3.5 mm 57명(57%), 3.6 mm 1명(1%)이였다. 2. 전체적인 눈의 세로 크기는 1.1 mm 52명 이하(52%), 1.2-1.4 mm 28명(28%), 1.5-1.7 mm 18명(18%), 1.8 mm 2명 이상(2%)이였다. 3. 전체적인 얼굴형태는 타원형이 29명(29%), 둥근형 24명(24%), 각진형 18명(18%), 세모형 29명(29%)이였다. 4. 남자의 얼굴형태는 타원형이 16명(32%), 둥근형 5명(10%), 각진형 13명(26%), 세모형 16명(32%)이였다. 5. 여자의 얼굴형태는 타원형이 15명(30%), 둥근형 20명(40%), 각진형 6명(12%), 세모형 9명(18%)이였다. 6. 전체적으로 PD에 비해 FPD가 너무 큰 경우 49명(49%), 적당한 크기 25명(25%), PD에 비해 FPD가 너무 작은 경우 26명(26%)이였다. 7. 남자는 PD에 비해 FPD가 너무 큰 경우 14명(28%), 적당한 크기 18명(36%), PD에 비해 FPD가 너무 작은 경우 18명(32%)이였다. 8. 여자는 PD에 비해 FPD가 너무 큰 경우 22명(44%), 적당한 크기 13명(26%), PD에 비해 FPD가 너무 작은 경우 15명(30%)이였다.

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갑상선 여포암의 초기 증상으로서의 단발성 두개골 전이 1예 (Solitary Skull Metastasis as the Initial Sign of Follicular Thyroid Cancer - A Case Report -)

  • 최수윤;차진우;송선춘;김장희;소의영
    • 대한두경부종양학회지
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    • 제23권1호
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    • pp.41-45
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    • 2007
  • A 60 years old female patient presented with $8{\times}6\;cm$ sized painless oval mass in the left parietal region. She had left lobectomy of thyroid gland 10 years ago. Cranial CT, MRI, FGD PET-CT showed a solid mass which invaded left parietal bone. After embolization, craniectomy with tumor excision was performed. Histological examination revealed metastatic follicular cancer originated thyroid gland, with vascular and dura invasion. Postoperatively, neck CT showed right thyroid multiple nodules and right level III multiple lymph node enlargement. Thyroid function test was normal, but level of thyroglobulin was high (72ng/ml). So she had right lobectomy of thyroid gland with lymph node dissection under a diagnosis of follicular carcinoma. But histological examination revealed adenomatous hyperplasia and not lymph node metastasis. After operation, she received radioiodine therapy of 150mCi and then the level of thyroglobulin normalized (8.4ng/ml). The patient is under follow-up since she had operation 4 months ago.

열간 선재 압연제품의 치수정밀도 향상을 위한 롤 갭 조정 (Adjustment of Roll Gap for The Dimension Accuracy of Bar in Hot Bar Rolling Process)

  • 김동환;김병민;이영석
    • 한국정밀공학회지
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    • 제19권6호
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    • pp.96-103
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    • 2002
  • The objective of this study is to adjust the roll gap fur the dimension accuracy of bar in hot bar rolling process considering roll wear. In this study hot bar rolling processes fur round and oval passes have been investigated. In order to predict the roll wear, the wear model is reformulated as an incremental from and then wear depth of roll is calculated at each deformation step on contact area using the results of finite element analysis, such as relative sliding velocity and normal pressure at contact area. Archard's wear model was applied to predict the roll wear. To know the effects of thermal softening of DCI (Ductile Cast Iron) roll material according to operating conditions, high temperature micro hardness test is executed and a new wear model has been proposed by considering the thermal softening of DCI roll expressed in terms of the main tempering curve. The new technique developed in this study for adjusting roll gap can give more systematically and economically feasible means to improve the dimension accuracy of bar with full usefulness and generality.