• Animal cells and systems
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• v.14 no.4
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• pp.267-274
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• 2010

The decrease in sperm quality under heat stress causes a great loss in animal husbandry production. In order to reveal the mechanism underlying the sperm quality decrease caused by heat stress, we first established a mild heat-treated mouse model. Then, the sperm quality was identified. Further, the testicular proteome profile was mapped and compared with the control using 2D electrophoresis and mass spectrometry. Finally, the differential expressed proteins involved in the heat stress response were identified by real-time PCR and Western blotting. The results showed that heat stress caused a significant reduction in mouse sperm quality (P<0.05). Further, 52 protein spots on the 2D gel were found to differ between the heat-shocked tissues and the control. Of these spots, some repair proteins which might provide some explanation for the influence on sperm quality were found. We then focused on Bag-1, Hsp40, Hsp60 and Hsp70, which were found to be differently expressed after heat shock (P<0.05). Further analysis in this heat-shocked model suggests numerous potential mechanisms for heat shock-induced spermatogenic disorders.

• Nuclear Engineering and Technology
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• v.32 no.6
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• pp.566-594
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• 2000

In most LMFBR(Liquid Metal Fast Breed Reactor) design, the operating temperature is very high and the time-dependent creep and stress-rupture effects become so important in reactor structural design. Therefore, unlike with conventional PWR, the normal operating conditions can be basically dominant design loading because the hold time at elevated temperature condition is so long and enough to result in severe total creep ratcheting strains during total service lifetime. In this paper, elevated temperature design of the conceptually designed baffle annulus regions of KALIMER(Korea Advanced Liquid MEtal Reactor) reactor internal strictures is carried out for normal operating conditions which have the operating temperature 53$0^{\circ}C$ and the total service lifetime of 30 years. For the elevated temperature design of reactor internal structures, the ASME Code Case N-201-4 is used. Using this code, the time-dependent stress limits, the accumulated total inelastic strain during service lifetime, and the creep-fatigue damages are evaluated with the calculation results by the elastic analysis under conservative assumptions. The application procedures of elevated temperature design of the reactor internal structures using ASME Code Case N-201-4 with the elastic analysis method are described step by step in detail. This paper will be useful guide for actual application of elevated temperature design of various reactor types accounting for creep and stress-rupture effects.

• Journal of Environmental Science International
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• v.21 no.3
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• pp.267-276
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• 2012

Spaceflights results in the reduction of immune status of human beings and increase in the virulence of microorganisms, especially gram negative bacteria. The growth of Klebsiella pneumoniae is enhanced by catecholamines and during spaceflight, elevation in the levels of cortisols occurs. So it is necessary to know the changes in physiology, virulence, antibiotic resistance and gene expression of K. pneumoniae under microgravity conditions. The present study was undertaken to study effect of simulated microgravity on growth, morphology, antibiotic resistance and cross stress resistance of K. pneumoniae to various stresses. The susceptibility of simulated microgravity grown K. pneumoniae to ampicillin, penicillin, streptomycin, kanamycin, hygromycin and rifampicin were evaluated. The growth of bacteria was found to be fast compared with normal gravity grown bacteria and no significant changes in the antibiotic resistance were found. The bacteria cultured under microgravity conferred cross stress resistance to acid, temperature and osmotic stress higher than the normal gravity cultured bacteria but the vice versa was found in case of oxidative stress.

• Korean Journal of Exercise Nutrition
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• v.23 no.1
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• pp.28-35
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• 2019

[Purpose] The purpose of this study was to investigate the effects of treadmill exercise on oxidative stress in the hippocampal tissue and mitochondrial dynamic-related proteins in rats fed a long-term high-fat diet (HFD). [Methods] Obesity was induced in experimental animals using high fat feed, and the experimental groups were divided into a normal diet-control (ND-CON; n=12), a high fat diet-control (HFD-CON; n=12) and a high fat diet-treadmill exercise (HFD-TE; n=12) group. The rats were subsequently subjected to treadmill exercise (progressively increasing load intensity) for 8 weeks (5 min at 8 m/min, then 5 min at 11 m/min, and finally 20 min at 14 m/min). We assessed weight, triglyceride (TG) concentration, total cholesterol (TC), area under the curve, homeostatic model assessment of insulin resistance, and AVF/body weight. Western blotting was used to examine expression of proteins related to oxidative stress and mitochondrial dynamics, and immunohistochemistry was performed to examine the immunoreactivity of gp91phox. [Results] Treadmill exercise effectively improved the oxidative stress in the hippocampal tissue, expression of mitochondrial dynamic-related proteins, and activation of NADPH oxidase (gp91phox) and induced weight, blood profile, and abdominal fat loss. [Conclusion] Twenty weeks of high fat diet induced obesity, which was shown to inhibit normal mitochondria fusion and fission functions in hippocampal tissues. However, treadmill exercise was shown to have positive effects on these pathophysiological phenomena. Therefore, treadmill exercise should be considered during prevention and treatment of obesity-induced metabolic diseases.

• Physical Therapy Rehabilitation Science
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• v.13 no.1
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• pp.134-142
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• 2024

Objective: This study aimed to compare the subjective health status, physical activity index, and perceived stress rate of obese children with those of healthy children through propensity matching analysis and to use the results to help manage obese children. Design: Descriptive correlation study. Methods: This study conducted a secondary analysis using raw data from the National Health and Nutrition Examination Survey. Propensity matching (1:2) was conducted between obese and healthy adolescents. Results: The number of days of physical activity was 1.22 days for the obese adolescent group and 1.01 days for the non-obese adolescent group, which was higher in the obese group (p=0.003). The subjective health status was 3.43 and 3.81 in the obese and non-obese adolescent groups, respectively, showing a higher difference in the normal group (p<0.001). No statistical difference was observed in the perceived stress rate (p=0.871) or strength exercises (p=0.190) between the two groups. Conclusion: This study suggests the need for development measures to effectively improve youth physical activity, muscle-strengthening programs, stress management, and subjective health status in obese and normal groups.

• Journal of the Korean earth science society
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• v.29 no.5
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• pp.437-445
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• 2008

We analyzed fault plane solutions of the recent twenty-two earthquakes which occurred from 2004 to 2006 in the central part of the Korean Peninsula by using P- and S-wave polarities along with SH/P amplitude ratios. The fault plane solution shows that strike-slip fault is dominant here, especially for the events with local magnitude equal to or greater than 3.0. However, some events with local magnitude less than 3.0 show normal fault or strike-slip fault with normal components. In the case of strike-slip fault, its orientation is almost in the direction of NNE-SSW to NE-SW almost parallel to the general trend of faults, while the compressional axis of the stress field trends ENE to E-W. The result is almost consistent with the stress field in and around the Korean peninsula, as reported previously. We cannot give any appropriate explanations to the normal faulting events along the western offshore and inland areas whether it is related to the local stress changes or tectonically unidentified extensional structures. Thus, an extension of investigations is desirable to clarify the cause of such phenomena.

• Tribology and Lubricants
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• v.22 no.3
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• pp.119-126
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• 2006

In this paper, the contact behavior characteristics of a primary sealing components such as a seal ring and a seal seat has been presented for a small hydro-power turbine. Using the non-linear FEM analysis, the maximum temperature, the axial displacement, radial differences between a seal ring and a seal seat, and maximum contact normal stress have been analyzed for three optimized sealing profiles in which are designed based on the FEM analysis and Taguchi's experimental method. The three primary sealing profiles between a seal ring and a seal seat are strongly related to a leakage of a water for a hydro-power turbine and wear of a primary sealing component. The computed results show that the contact rubbing area between a seal ring and a seal seat is very important for reducing a friction heating and wear in a sealing gap, and increasing a contact normal stress in primary sealing components. Based on the FEM computation, models II and III in which have a small rubbing surface of seal rings show low dilatation of primary sealing components, and high normal contact stress between a seal ring and a seal seat. Thus, the FEM computed results recommend a short contacting width of a primary sealing component for reducing a leakage and thermal distortions, and expanding a seal life. This means that a conventional primary sealing component may be switched to a reduced sealing face of seal rings.

• Journal of the Korean Geosynthetics Society
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• v.8 no.4
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• pp.1-8
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• 2009

In this study, the large-scale pullout tests are conducted to evaluate pullout resistance of steel strip reinforcement with transverse members. The test results clearly showed the passive effect by normal stress. This suggests that both friction resistance and passive resistance by normal stress should be taken into account in the evaluation of pullout resistance for design. Therefore, The evaluation results confirmed that the developed steel strip reinforcement with transverse members depend heavily on passive resistance by normal stress.

• Structural Engineering and Mechanics
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• v.61 no.5
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• pp.637-643
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• 2017

Carbon fiber reinforced polymers (CFRPs) have been recently investigated as an alternative material for Geosynthetics to improve soil properties. One of the factors influencing the fiber orientation and mechanical properties of CFRP is the effect of soil overburden pressure. This study investigates the tensile behavior of cast-in-place CFRP. During the curing time of specimens, a wide range of normal stress is applied on specimens sandwiched between the soils. Two different soil types are used to determine the effect of soil grain size on the mechanical properties of CFRP. Specimens are also prepared with different specifications such as curing time and mixing soil in to the epoxy. In this study, tensile tests are conducted to investigate the effect of such parameters on tensile behavior of CFRP. The experimental results indicate that by increasing the normal stress and soil grain size, the ultimate tensile strength and the corresponding strain of CFRP decrease; however, reduction in elastic modulus is not noticeable. It should be noted that, increasing the curing period of epoxy resin and mixing soil in to the epoxy have no significant effect on the tensile properties of CFRP.

• Journal of Oriental Neuropsychiatry
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• v.17 no.3
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• pp.57-65
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• 2006

Objectives: The purpose of this research is to investigate the effects of Benson's Relaxation Technique on autonomic nervous system for normal subjects with Heart Rate Variability(HRV) and find out relationship with anti - stress effects. Methods: First, Benson's Relaxation Technique was applied on 5 normal subjects for three weeks. Then HRV was examined for 15 minutes Benson's Relaxation Technique application. Next, Benson's Relaxation Technique each 8 times was applied on 5 normal subjects for 1 weeks. Then :HRV was examined each 5 minutes before and after Benson's Relaxation Technique application. Results: 1. SDNN, SDSD increased continuously in HRV for three weeks Benson's Relaxation Technique application. 2. Mean HRV, SDNN, SDSD were significant different in HRV between before and after Benson's Relaxation Technique application at fourth week. Conclusion: The results suggest that Benson's Relaxation Technique application have shown anti-stress effects and the more Benson's Relaxation Technique is repeated, the more effective.