• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.20-28
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• 2019

This study comparatively analyzes general walking shoes on the conical top foundation of the ground condition and the pressure distribution during walking with shoes that are currently under development. Two categories of footwear were used: general footwear and a footwear conical top foundation that is currently under development. Experiments were carried out on hard ground and sandy soil in 15 male twenties that satisfy the conditions of normal foot wearing 260 mm. The pressure during walking was measured using Techstorm's Wireless Insole System, and foot pressure was measured in 7 zones of the foot. Studies have shown different maximum forces, average pressures, and pressure distributions depending on the shoe and ground conditions. This study shows that shoes with general low pressure dispersion effects depending on the feet in hard ground and sand ground are different from shoes with the conical top foundation that is currently under development. It is expected that it will be useful for the development of shoes that can be worn in all hard ground and sandy ground by selecting various rubber materials through further research.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.12 no.4
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• pp.456-465
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• 2019

PHEV(Plug in Hybrid Electric Vehicle) and BEV(Battery Electric Vehicle) equip high voltage batteries to drive motor and vehicle electric system. Those vehicle require OBC(On-Board Charger) for charging batteries and LDC(Low DC/DC Converter) for converting from high voltage to low voltage. Since the charger and the converter actually separate each other in electrical vehicles, there is a margin to reduce the vehicle weight and area of installation by integration two systems. This paper studies a 1.5kW LDC converter that can be integrated into an OBC using an isolated current-fed converter by simplifying the design of LDC transformers. The proposed LDC can control the final output voltage of the LDC by using a fixed arbitrary output voltage of the bidirectional buck-boost converter, so that Compared to the existing OBC-LDC integrated system, it has the advantage of simplifying the transformer design considering the battery voltage range, converter duty ratio and OBC output turn ratio. Prototype of the proposed LDC was made to confirm normal operation at 200V ~ 400V input voltage and maximum efficiency of 91.885% was achieved at rated load condition. In addition, the OBC-LDC integrated system achieved a volume of about 6.51L and reduced the space by 15.6% compared to the existing independent system.

• Plant Journal
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• v.14 no.4
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• pp.33-38
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• 2018

In this study, it was confirmed whether the cooling water bypass ratio of packing for plume abatement matched designed value during winter operation of combined cycle power plant. Designed operating wet bulb temperature of the plume abatement cooling tower with 29 Gcal/h capacity had a range from $13^{\circ}C$ to $-20^{\circ}C$, while its designed bypass ratio was from 0 % to 78%, so that increasing rate of the designed bypass ratio was $2.36%/^{\circ}C$ when the external temperature decreased. When the wet bulb temperature at cooling tower inlet had a range from $7.8^{\circ}C$ to $-11.8^{\circ}C$ in a normal operation, it was measured that actual bypass ratio of packing for plume abatement had a range from 23.8 % to 74.3%. While increasing rate of the actual bypass ratio was $2.71%/^{\circ}C$ in a range from $7.8^{\circ}C$ to $-9.55^{\circ}C$, it was $1.61%/^{\circ}C$ under $-10^{\circ}C$ in cold weather condition according to atmospheric temperature drop, therefore it was confirmed that the increasing rate of the bypass ratio for packing was lowered than its design.

• Journal of Life Science
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• v.30 no.12
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• pp.1118-1127
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• 2020

Alzheimer's disease causes progressive neuronal loss that leads to cognitive disturbances. It is not currently curable, and there is no way to stop its progression. However, since medical treatment for Alzheimer's disease is most effective in the early stages, early detection can provide the best chance for symptom management. Biomarkers for the diagnosis of Alzheimer's disease include amyloid β (Aβ) deposition, pathologic tau, and neurodegeneration. Aβ deposition and phosphorylated tau can be detected by cerebrospinal fluid (CSF) analysis or positron emission tomography (PET). However, CSF sampling is quite invasive, and PET analysis needs specialized and expensive equipment. During the last decades, blood-based biomarker analysis has been studied to develop fast and minimally invasive biomarker analysis method. And one of the remarkable findings is the involvement of platelets as a primary source of Aβ in plasma. Aβ can be transported across the blood - brain barrier, creating an equilibrium of Aβ levels between the brain and blood under normal condition. Interestingly, a number of clinical studies have unequivocally demonstrated that plasma Aβ42/Aβ40 ratios are reduced in mild cognitive impairment and Alzheimer's disease. Together, these recent findings may lead to the development of a fast and minimally invasive early diagnostic approach to Alzheimer's disease. In this review, we summarize recent advances in the biomarkers of Alzheimer's disease, especially the involvement of platelets as a source of peripheral Aβ production and its potential as a blood-based biomarker.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.553-564
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• 2021

This study analyzed the the risk of halogen lamp for pigsty heating and its fire prevention. Halogen lamps are used for keeping warm in pen because of their excellent economy and convenience. However, there is a high risk of fire due to poor safety management and exposure to animal movements. In fact, after exploring old pigsty and cattle shed, it was easy to confirm that they were exposed to fire risks. We noted this point and studied the possibility of fire by experiment due to combustible contact with halogen lamp and carelessness in use. The experiment was conducted under conditions similar to the actual use environment. After installing halogen lamps to the height used in actual pen, the temperature change was observed with infrared camera with straw, sawdust and rice husks on the floor. And assuming abnormal conditions, the experiment was also conducted under conditions the lamp dropped on the floor or combustible material came into contact with the glass tube inside the lamp. If halogen lamps were used in normal condition, there was no risk of fire. However, in abnormal use environments, smoke comes out or even ignited. Even if it is convenient for use or highly utilized, high risk of fire will require setting up fire prevention measures or regulation of use. Through in-depth fire investigation and research, we should promote the risk of fire and make efforts to prevent fire to minimize human life and property damage.

• Journal of Oriental Neuropsychiatry
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• v.32 no.2
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• pp.81-93
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• 2021

Objectives: Mild cognitive impairment (MCI) is condition of cognitive decline shown in transition from normal aging to dementia. Hominis placenta pharmacopuncture (HPP) is a treatment that combines effects of medication and acupuncture by injecting Hominis placenta into acupoints. The objective of this study was to evaluate the efficacy and safety of HPP for MCI. Methods: This was a randomized, double-blind, placebo-controlled, two-center clinical trial. Eligible patients were randomly allocated to either the HPP group or the placebo group. HPP or saline as placebo was administered to participants for eight weeks. Changes in symptoms were observed. The primary outcome was difference in mean change of Korean Version of the Montreal Cognitive Assessment (MoCA-K) score between the HPP group and the placebo group. Cognitive function, overall status of mood and sleep, and quality of life (QoL) were also assessed. Safety assessment and economic analysis were then conducted. Results: Thirty participants were enrolled. One participant in the placebo group dropped out. The score of MoCA-K increased after treatment. Its mean change was smaller in the HPP group than in the control group. HPP ameliorated Global Deterioration Scale and Korean Dementia Rating Scale subtests for attention, organization, and memory compared to the placebo. However, none of them was significantly different between the two groups. Mood, sleep, and QoL all improved more in the HPP group than in the placebo group, although differences between the two groups were not statistically significant. There was no adverse event probably related to the drug. HPP treatment needed KRW 345,000 more than the placebo group in improving Geriatric Quality of Life scale-Dementia score by one point for one year. Conclusions: Although HPP treatment did not significantly improve cognition, it changed behavioral and psychological symptoms in MCI.

• Journal of the Korean Society of Radiology
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• v.16 no.3
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• pp.211-216
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• 2022

In radiation therapy, accurate Quality Assurance (QA) is required to irradiate tumor tissue while minimizing damage to normal tissue. Therefore, a dosimeter that can accurately measure radiation is needed. The purpose of this study is to develop a highly efficient radiation dosimeter with high sensitivity by applying a particle in binder method that can reduce manufacturing costs and simplify processes to perovskite materials that are cheaper and simpler to manufacture. By evaluating the response characteristics to high-energy photon, the applicability of QA dosimeter to radiation therapy was evaluated. As a result of reproducibility evaluation, RSD at 6 MV energy was presented as 1.178% and 15 MV energy was presented as 1.141%. As a result of linearity evaluation according to linear regression analysis, R² values of 0.9999 were presented under each condition of 6 MV and 15 MV energy. It was found that the CsPbBr₃ dosimeter manufactured based on the results of reproducibility and linearity evaluation is highly applicable as a QA dosimeter in the field of therapeutic radiation. The CsPbBr₃ dosimeter manufactured in this study presented more than the standard performance in the evaluation of reproducibility and linearity, and it can be used as a radiotherapy QA dosimeter through improvement.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.2
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• pp.95-104
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• 2022

Objectives : This study is to report a case of otitis media with effusion accompanied by atopic dermatitis improved by Korean medicine monotherapy. Methods : A 31-year-old woman patient visited our clinic for aural fullness, hearing loss, and tinnitus of the left ear on August 14th, 2021. She also had abdominal pain, diarrhea, and general weakness because of side effects of antibiotics. Besides, she had nasal congestion, rhinorrhea, and dry skin. Through otoscopy, her tympanum was fully filled with yellow effusion. She only took Korean medicine therapy including acupuncture and herbal medicine weekly. The treatment continued for about 4 months(total 14 visits) until December 4th, 2021. Otoscopy, numerical rating scale(NRS), scoring atopic dermatitis(SCORAD) index were used to assess the symptoms. Results : On August 30, 2021, her intestinal symptoms improved. The left tympanum was recovered to normal condition as the treatment continued. The effusion disappeared on October 16th, 2021. On November 6th, 2021, peritympanic blood congestion also almost alleviated. Subjective symptoms including aural fullness, hearing loss, and tinnitus disappeared on October 16, 2021. Nasal symptoms and dry skin also improved. The SCORAD index dropped from 15 to 4. Conclusions : These results suggests that otitis media with effusion can be sufficiently managed by Korean medicine therapy. Further, active application of Korean medicine therapy to common otolaryngological diseases is necessary.

• Journal of the Korean Society of Safety
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• v.37 no.1
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• pp.64-69
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• 2022

The study measured a subway construction worker's Macpa stress by Heart Rate Variability measuring instrument and conducted a survey of Korean job stress from subway construction workers. Also, the study analyzed the relationship between Macpa stress index and Korean job stress result and suggested managing stress method for each item. According to National Statistical Office data, the first line subway in Seoul was started to open in 1974. The extended total length is 996 kilometers until 2019. Many aged workers are currently working at subway construction sites due to the avoidance of young workers since the past until now. It means that the elderly has a substantial portion among subway construction workers. The productivity has been adversely affected by health problems due to the aging of workers, job stress due to heavy work, and personal health problems. So, the regulation and policies on job stress health management are being strengthened. The data were measured Macpa stress by machine measuring heart rate variability and conducted Korean job stress survey(shortened) from Sa-sang to Ha-dan line Busan subway construction workers for analyzing the relationship. Independent variable were age, job duration, job position, employment type, working type in this study. Macpa's dependent variable was stress index and Korean job stress survey(shortened)'s dependent variables were job requirements, job autonomy, relationship conflict, job instability, organizational structure, inappropriate compensation, working place culture, and total score. SPSS 12.0 K Statistics Program was used for statistical analysis. Kruskal-wallis test, a nonparametric statistical analysis, was used because the data are difficult to be assumed as normal distribution. As a result, the paper indicated the significant correlation between Macpa stress index and Korean job stress(short version). The elderly workers presented higher Macpa index and higher job stress due to aging and heavy-duty work. The majority workers were daily workers who had unstable working condition and uncertainty about the future. The study suggested a manual that could reduce job stress for subway construction workers and future study deriving management tool through analyzing job stress factor is necessary.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.1
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• pp.104-112
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• 2022

The purpose of this study is to analyze the fracture resistance of reattached tooth according to the resin materials and tooth preparation type under physiological conditions. Uncomplicated crown fracture in the oblique direction was reproduced on the extracted 64 anterior teeth. Depending on the composite resin material, reattachment was performed using a flowable resin and a packable resin. Depending on retentive forms, reattachment was performed using simple reattachment, 1.0 mm × 1.0 mm labial chamfer bevel, 1.0 mm × 1.0 mm lingual chamfer bevel and 1.0 mm × 1.0 mm circumferential bevel. A load was applied to the palatal surface of the tooth using a universal testing machine at an angle of 125 degree, which is the interincisal angle of normal children. Under the masticatory pressure condition, fracture resistance of lingual chamfer groups was 28.28 ± 7.41 MPa and 27.54 ± 4.45 MPa, which was significantly higher than those of simple reattachment groups, 17.21 ± 5.87 MPa and 20.10 ± 6.00 MPa, in both flowable and packable resin groups. When considering the lingual force similar to masticatory pressure, the fragment retention was significantly improved when the lingual chamfer was formed compared to the simple reattachment. Clinicians may consider the design of the lingual chamfer in order to improve fracture resistance to masticatory pressure during fragment reattachment.