• 대한의용생체공학회:의공학회지
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• 제13권3호
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• pp.181-188
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• 1992

This paper provides an overview of system analysis of immunology. The theoretical research in this area is aimed at an understanding of the precise manner by which the immune system controls Infec pious diseases, cancer, and AIDS. This can provide a systematic plan for immunological experimentation by means of an integrated program of immune system analysis, mathematical modeling and computer simulation. Biochemical reactions and cellular fission are naturally modeled as nonlinear dynamical processes to synthesize the human immune system! as well as the complete organism it is intended to protect. A foundation for the control of tumors is presented, based upon the formulation of a realistic, knowledge based mathematical model of the interaction between tumor cells and the immune system. Ordinary bilinear differential equations which are coupled by such nonlinear term as saturation are derived from the basic physical phenomena of cellular and molecular conservation. The parametric control variables relevant to the latest experimental data are also considered. The model consists of 12 states, each composed of first-order, nonlinear differential equations based on cellular kinetics and each of which can be modeled bilinearly. Finally, tumor control as an application of immunotherapy is analyzed from the basis established.

• Structural Engineering and Mechanics
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• 제52권5호
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• pp.937-956
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• 2014

The MEMS structures usually are made from silicon; consideration of the viscoelastic effect in microbeams duo to the phenomena of silicon creep is necessary. Application of the fractional model of microbeams made from viscoelastic materials is studied in this paper. Quasi-static and dynamical responses of an electrically actuated viscoelastic microbeam are investigated. For this purpose, a nonlinear finite element formulation of viscoelastic beams in combination with the fractional derivative constitutive equations is elucidated. The four-parameter fractional derivative model is used to describe the constitutive equations. The electric force acting on the microbeam is introduced and numerical methods for solving the nonlinear algebraic equation of quasi-static response and nonlinear equation of motion of dynamical response are described. The deflected configurations of a microbeam for different purely DC voltages and the tip displacement of the microbeam under a combined DC and AC voltages are presented. The validity of the present analysis is confirmed by comparing the results with those of the corresponding cases available in the literature.

• Advances in nano research
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• 제5권2호
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• pp.69-97
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• 2017

In this study, nonlinear response of laminated functionally graded carbon nanotube reinforced composite (FG-CNTRC) plate under low-velocity impact based on the Eshelby-Mori-Tanaka approach in thermal conditions is studied. The governing equations are derived based on higher-order shear deformation plate theory (HSDT) under von $K\acute{a}rm\acute{a}n$ geometrical nonlinearity assumptions. The finite element method with 15 DOF at each node and Newmark's numerical integration method is applied to solve the governing equations. Four types of distributions of the uniaxially aligned reinforcement material through the thickness of the plates are considered. Material properties of the CNT and matrix are assumed to be temperature dependent. Contact force between the impactor and the laminated plate is obtained with the aid of the modified nonlinear Hertzian contact law models. In the numerical example, the effect of layup (stacking sequence) and lamination angle as well as the effect of temperature variations, distribution of CNTs, volume fraction of the CNTs, the mass and the velocity of the impactor in a constant energy level and boundary conditions on the impact response of the CNTRC laminated plates are investigated in details.

• Advances in aircraft and spacecraft science
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• 제7권3호
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• pp.215-228
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• 2020

As is shown in the paper, the Koltunov-Rzhanitsyn singular kernel of heredity (when constructing mathematical models of the dynamics problem of the hereditary theory of viscoelasticity) adequately describes real mechanical processes, best approximates experimental data for a long period of time. A mathematical model of the problem of the flutter of viscoelastic plates moving in a gas with a high supersonic velocity is given. Using the Bubnov-Galerkin method, discrete models of the problem of the flatter of viscoelastic plates flowed over by supersonic gas flow are obtained. A numerical method is developed to solve nonlinear integro-differential equations (IDE) for the problem of the hereditary theory of viscoelasticity with weakly singular kernels. A general computational algorithm and a system of application programs have been developed, which allow one to investigate the nonlinear dynamic problems of the hereditary theory of viscoelasticity with weakly singular kernels. On the basis of the proposed numerical method and algorithm, nonlinear problems of the flutter of viscoelastic plates flowed over in a gas flow at an arbitrary angle are investigated. In a wide range of changes in various parameters of the plate, the critical velocity of the flutter is determined. It is shown that the singularity parameter α affects not only the oscillations of viscoelastic systems, but the critical velocity of the flutter as well.

• Coupled systems mechanics
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• 제10권1호
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• pp.39-60
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• 2021

The present paper is concerned with the study of nonlinear ultrasonic waves in a magneto thermo (MT) elastic armchair single-walled carbon nanotube (ASWCNT) resting on polymer matrix. The analytical formulation is developed based on Eringen's nonlocal elasticity theory to account small scale effect. After developing the formal solution of the mathematical model consisting of partial differential equations, the frequency equations have been analyzed numerically by using the nonlinear foundations supported by Winkler-Pasternak model. The solution is obtained by ultrasonic wave dispersion relations. Parametric work is carried out to scrutinize the influence of the non local scaling, magneto-mechanical loadings, foundation parameters, various boundary condition and length on the dimensionless frequency of nanotube. It is noticed that the boundary conditions, nonlocal parameter, and tube geometrical parameters have significant effects on dimensionless frequency of nano tubes. The results presented in this study can provide mechanism for the study and design of the nano devices like component of nano oscillators, micro wave absorbing, nano-electron technology and nano-electro- magneto-mechanical systems (NEMMS) that make use of the wave propagation properties of armchair single-walled carbon nanotubes embedded on polymer matrix.

• Advances in nano research
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• 제10권4호
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• pp.385-395
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• 2021

This research concentrates on the effects of distributions and volume fractions of carbon nanotubes (CNT) on the nonlinear bending behavior of deep cylindrical panels reinforced by functionally graded carbon nanotubes under thermo-mechanical loading, hitherto not reported in the literature. Assuming the effects of shear deformation and moderately high value of the radius-to-side ratio (R/a), based on the first-order shear deformation theory (FSDT) and von Karman type of geometric nonlinearity, the governing system of equations is obtained. The analytical solution of field equations is carried out using the Ritz method together with the Newton-Raphson iterative scheme. The effects of radius-to-side ratio, temperature change, and boundary conditions on the nonlinear response of the functionally graded carbon nanotubes reinforced composite deep cylindrical panel (FG-CNTRC) are investigated. It is concluded that, among the five possible distribution patterns of CNT, FG-V CNTRC deep cylindrical panel is strongest with the highest bending moment and followed by UD, X, O, and Ʌ-ones. Also, considering the present deep cylindrical panel formulation increases the accuracy of the results. Hence, according to the noticeable amount of R/a in FG-CNTRC cylindrical panels, it is mandatory to apply strain-displacement relations of deep cylindrical panels for bending analysis of FG-CNTRC which certainly is desirable for industrial application.

• Steel and Composite Structures
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• 제43권5호
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• pp.533-552
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• 2022

The current article deals with the dynamic stability, and structural improvement of vibrating electrically curved screen on the viscoelastic substrate. By considering optimum value for radius curvature of the electrically curved screen, the structure improvement of the system occurs. For modeling the electrically system, the Maxwell's' equation is developed. Hertz contact model in employed to obtain contact forces between impactor and structure. Moreover, variational methods and nonlinear von Kármán model are used to derive boundary conditions (BCs) and nonlinear governing equations of the vibrating electrically curved screen. Galerkin and Multiple scales solution approach are coupled to solve the nonlinear set of governing equations of the vibrating electrically curved screen. Along with the analytical solution, 3D finite element simulation via ABAQUS package is provided with the aid of a FE package for simulating the current system's response. The results are categorized in 3 different sections. First, effects of geometrical and material parameters on the vibrational performance and stability of the curves panel. Second, physical properties of the impactor are taken in to account and their effect on the absorbed energy and velocity profile of the impactor are presented. Finally, effect of the radius and initial velocity on the mode shapes of the current structure is demonstrated.

• 한국지반공학회논문집
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• 제38권12호
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• pp.103-112
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• 2022

본 연구에서는 시간-침하량 계측 데이터를 기반으로 한 기존 침하 예측 이론식을 확인하였다. 기존 계측 기반 침하 예측 이론식 중 쌍곡선법 및 Asaoka법이 정확도가 높게 나타났으며, 이외 방법은 정확도가 낮은 것으로 확인되었다. 이러한 분석 결과를 토대로 기존 침하 예측 방법의 한계점을 도출하였으며, 이러한 한계점을 보완할 수 있는 개선방안으로써 가중 비선형 회귀분석을 통한 침하 예측 방법을 제시하였다.

• 한국항만학회지
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• 제12권1호
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• pp.75-86
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• 1998

To design a coastal structure in the nearshore region, engineers must have means to estimate wave climate. Waves, approaching the surf zone from offshore, experience changes caused by combined effects of bathymetric variations, interference of man-made structure, and nonlinear interactions among wave trains. This paper has attempted to find out the effects of two of the more subtle phenomena involving nonlinear shallow water waves, amplitude dispersion and secondary wave generation. Boussinesq-type equations can be used to model the nonlinear transformation of surface waves in shallow water due to effect of shoaling, refraction, diffraction, and reflection. In this paper, generalized Boussinesq equations under the complex bottom condition is derived using the depth averaged velocity with the series expansion of the velocity potential as a product of powers of the depth of flow. A time stepping finite difference method is used to solve the derived equation. Numerical results are compared to hydraulic model results. The result with the non-linear dispersive wave equation can describe an interesting transformation a sinusoidal wave to one with a cnoidal aspect of a rapid degradation into modulated high frequency waves and transient secondary waves in an intermediate region. The amplitude dispersion of the primary wave crest results in a convex wave front after passing through the shoal and the secondary waves generated by the shoal diffracted in a radial manner into surrounding waters.

• Nonlinear Functional Analysis and Applications
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• 제28권2호
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• pp.497-520
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• 2023

Numerous problems in science and engineering defined by nonlinear functional equations can be solved by reducing them to an equivalent fixed point problem. Fixed point theory provides essential tools for solving problems arising in various branches of mathematical analysis, such as split feasibility problems, variational inequality problems, nonlinear optimization problems, equilibrium problems, complementarity problems, selection and matching problems, and problems of proving the existence of solution of integral and differential equations.The theory of fixed is known to find its applications in many fields of science and technology. For instance, the whole world has been profoundly impacted by the novel Coronavirus since 2019 and it is imperative to depict the spread of the coronavirus. Panda et al. [24] applied fractional derivatives to improve the 2019-nCoV/SARS-CoV-2 models, and by means of fixed point theory, existence and uniqueness of solutions of the models were proved. For more information on applications of fixed point theory to real life problems, authors should (see [6, 13, 24] and the references contained in).