• Title/Summary/Keyword: Non-mixture

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The Physiological Activity of Crude Polysaccharide Solvent Extracted from Herbal Medicine Mixture (생약복합물 용매추출물과 조다당획분의 생리활성)

  • Shin, Hyun-Young;Kim, Hoon;Shin, Ji-Young;Lee, Sue Jung;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.34 no.1
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    • pp.36-46
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    • 2021
  • After ethanol (BM-E and RW-E) and hot-water (BM-HW and RW-HW) extracts were fractionated from two herbal mixtures (BM and RW), their physiological activities were investigated. All extracts consisted of more than 50% of neutral sugar, with their total polyphenol levels higher than flavonoid levels. Radical scavenging activities of EtOH extracts remained significantly higher compared to that of hot-water extracts, and in particular, RW-E showed consistently higher antioxidant activity than BM-E. When anti-inflammatory activities of the extracts were evaluated by LPS-stimulated RAW 264.7 cells at 10~500 μg/mL non-cytotoxicity doses, BM-E showed significantly higher levels of TNF-α, IL-1β, IL-6, and nitric oxide inhibitory activity than those of hot-water extracts and RW-E. Murine peritoneal macrophage cells were shown to be enhanced in crude polysaccharides (BM-CP and RW-CP fractionated from BM-HW and RW-HW) compared to hot-water extracts and polysaccharide K (PSK, positive control). Especially, RW-CP exhibited higher activity than BM-CP, and component sugar analysis showed that BM-CP mainly contained galacturonic acid, glucose, arabinose, galactose, and xylose (34.5%, 33.9%, 16.1%, 7.1%, and 6.3%, respectively), whereas RW-CP showed different measurements (29.5%, 59.2%, 5.0%, 4.5%, and 0.2%). In conclusion, two herbal mixtures could contain varying sets of physiological activities dependent on different extraction and fractionation methods.

A New Approach for Detection of Gear Defects using a Discrete Wavelet Transform and Fast Empirical Mode Decomposition

  • TAYACHI, Hana;GABZILI, Hanen;LACHIRI, Zied
    • International Journal of Computer Science & Network Security
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    • v.22 no.2
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    • pp.123-130
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    • 2022
  • During the past decades, detection of gear defects remains as a major problem, especially when the gears are subject to non-stationary phenomena. The idea of this paper is to mixture a multilevel wavelet transform with a fast EMD decomposition in order to early detect gear defects. The sensitivity of a kurtosis is used as an indicator of gears defect burn. When the gear is damaged, the appearance of a crack on the gear tooth disrupts the signal. This is due to the presence of periodic pulses. Nevertheless, the existence of background noise induced by the random excitation can have an impact on the values of these temporal indicators. The denoising of these signals by multilevel wavelet transform improves the sensitivity of these indicators and increases the reliability of the investigation. Finally, a defect diagnosis result can be obtained after the fast transformation of the EMD. The proposed approach consists in applying a multi-resolution wavelet analysis with variable decomposition levels related to the severity of gear faults, then a fast EMD is used to early detect faults. The proposed mixed methods are evaluated on vibratory signals from the test bench, CETIM. The obtained results have shown the occurrence of a teeth defect on gear on the 5th and 8th day. This result agrees with the report of the appraisal made on this gear system.

Characteristics of Static Buckling Load of the Hexagonal Spatial Truss Models using Timber (목재를 이용한 육각형 공간 트러스 모델의 정적좌굴하중 특성)

  • Ha, Hyeonju;Shon, Sudeok;Lee, Seungjae
    • Journal of Korean Association for Spatial Structures
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    • v.22 no.3
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    • pp.25-32
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    • 2022
  • In this paper, the instability of the domed spatial truss structure using wood and the characteristics of the buckling critical load were studied. Hexagonal space truss was adopted as the model to be analyzed, and two boundary conditions were considered. In the first case, the deformation of the inclined member is only considered, and in the second case, the deformation of the horizontal member is also considered. The materials of the model adopted in this paper are steel and timbers, and the considered timbers are spruce, pine, and larch. Here, the inelastic properties of the material are not considered. The instability of the target structure was observed through non-linear incremental analysis, and the buckling critical load was calculated through the singularities and eigenvalues of the tangential stiffness matrix at each incremental step. From the analysis results, in the example of the boundary condition considering only the inclined member, the critical buckling load was lower when using timber than when using steel, and the critical buckling load was determined according to the modulus of elasticity of timber. In the case of boundary conditions considering the effect of the horizontal member, using a mixture of steel and timber case had a lower buckling critical load than the steel case. But, the result showed that it was more effective in structural stability than only timber was used.

α-Glucosidase Inhibitory Activity of Phenolic Compounds Isolated from the Stems of Caesalpinia decapetala var. japonica

  • Le, Thi Thanh;Ha, Manh Tuan;Hoang, Le Minh;Vu, Ngoc Khanh;Kim, Jeong Ah;Min, Byung Sun
    • Natural Product Sciences
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    • v.28 no.3
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    • pp.143-152
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    • 2022
  • In our study, sixteen known phenolic compounds, including quercetin (1), methyl gallate (2), caesalpiniaphenol C (3), 8S,8'S,7'R-(-)-lyoniresinol (4), 7,3',5'-trihydroxyflavanone (5), sappanchalcone (6), sappanone A (7), taxifolin (8), fisetin (9), fustin (10), (+)-catechin (11), brazilin (12), 3,4,5-trimethoxyphenyl β-ᴅ-glucopyranoside (13), 1-(2-methylbutyryl)phloroglucinol-glucopyranoside (14), (+)-epi-catechin (15), and astragalin (16) and one mixture of two conformers of protosappanin B (17/18) were isolated from the stems of Caesalpinia decapetala var. japonica. Their structures were elucidated based on a comparison of their physicochemical and spectral data with those of literature. To the best of our knowledge, this represents the first isolation of compounds 3, 4, 8, 9, and 10 from C. decapetala and compounds 13 and 14 from the Caesalpinia genus. All the isolated compounds were evaluated for their inhibitory effect against the α-glucosidase enzyme. Among them, two flavonols (1 and 9), one chalcone (6), and one homoisoflavanone (7) exhibited an inhibitory effect on α-glucosidase action with an IC50 range value of 5.08-15.01 μM, stronger than that of the positive control (acarbose, IC50 = 152.22 μM). Kinetic analysis revealed that compounds 1 and 9 showed non-competitive α-glucosidase inhibition, while the inhibition type was mixed for compounds 6 and 7.

Three-dimensional vibration analysis of 3D graphene foam curved panels on elastic foundations

  • Zhao, Li-Cai;Chen, Shi-Shuenn;Khajehzadeh, Mohammad;Yousif, Mariwan Araz;Tahouneh, Vahid
    • Steel and Composite Structures
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    • v.43 no.1
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    • pp.91-106
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    • 2022
  • This paper has focused on presenting a three dimensional theory of elasticity for free vibration of 3D-graphene foam reinforced polymer matrix composites (GrF-PMC) cylindrical panels resting on two-parameter elastic foundations. The elastic foundation is considered as a Pasternak model with adding a Shear layer to the Winkler model. The porous graphene foams possessing 3D scaffold structures have been introduced into polymers for enhancing the overall stiffness of the composite structure. Also, 3D graphene foams can distribute uniformly or non-uniformly in the shell thickness direction. The effective Young's modulus, mass density and Poisson's ratio are predicted by the rule of mixture. Three complicated equations of motion for the panel under consideration are semi-analytically solved by using 2-D differential quadrature method. The fast rate of convergence and accuracy of the method are investigated through the different solved examples. Because of using two-dimensional generalized differential quadrature method, the present approach makes possible vibration analysis of cylindrical panels with two opposite axial edges simply supported and arbitrary boundary at the curved edges. It is explicated that 3D-GrF skeleton type and weight fraction can significantly affect the vibrational characteristics of GrF-PMC panel resting on two-parameter elastic foundations.

Engineering characteristics of dune sand-fine marble waste mixtures

  • Qureshi, Mohsin U.;Mahmood, Zafar;Farooq, Qazi U.;Qureshi, Qadir B.I.L.;Al-Handasi, Hajar;Chang, Ilhan
    • Geomechanics and Engineering
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    • v.28 no.6
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    • pp.547-557
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    • 2022
  • Dune sands are poorly graded collapsible soils lacking fines. This experimental study explored the technical feasibility of sustainable invigoration of fine waste materials to improve the geotechnical properties of dune sand. The fine waste considered in this study is fine marble waste. The fine waste powder was mixed with dune sand at different contents (5, 10,15, 20, 25, 50%), where the gradation, void ratio, compaction, and shear strength characteristics were assessed for each fine marble waste -dune sand blend. The geotechnical properties of the dune sand-fine marble waste mix delineated in this study reveal the enhancement in compaction and gradation characteristics of dune sand. According to the results, the binary mixture of dune sand with 20% of fine marble waste gives the highest maximum dry density and results in shear strength improvement. In addition, a numerical study is conducted for the practical application of the binary mix in the field and tested for an isolated shallow foundation. The elemental analysis of the fine marble waste confirms that the material is non-contaminated and can be employed for engineering applications. Furthermore, the numerical study elucidated that the shallow surface replacement of the site with the dune sand mixed with 20% fine marble waste gives optimal performance in terms of stress generation and settlement behavior of an isolated footing. For a sustainable mechanical performance of the fine marble waste mixed sand, an optimum dose of 20% fine marble waste is recommended, and some correlations are proposed. Thus, for improving dune sand's geotechnical characteristics, the addition of fine marble waste to the dune sand is an environment-friendly solution.

Weedy Rice Occurrence Rate and Position in Transplanted and Direct Seeded Farmer's Field (농가포장에서 재배양식별 앵미(잡초성 벼)의 발생정도 및 입치)

  • Suh, Hak-Soo;Back, Jun-Ho;Ha, Woon-Goo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.3
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    • pp.352-356
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    • 1997
  • In order to trace the survival route of weedy rice in Korean farmer's field, occurrence rate and position of weedy rice, number of weedy rice plants per $m^2$, in transplanted and direct seeded field were investigated. The highest occurrence rate of weedy rice in transplanted field was 5.5%. Number of weedy rice plants in direct seeded field was higher than that in transplanted field. In transplanted field, most of the weedy rice were grown within hills of cultivated rice and only a few was grown between hills of the cultivated rice, however in direct seeded field the number of weedy rice occurred between hills or rows of cultivated rice was higher than that occurred within hills or rows. Weedy rice occurrence rate in the field of .non-recommended rice variety was higher than that in the field of recommended variety. The main survival route of weedy rice in transplanted field was supposed to be mixture of weedy rice seeds with cultivated rice, and that in direct seeded field to be natural survival.

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Automated radiochemical synthesis of [18F]FET on TRACERlab FX2N module and its quality control

  • Dong Hyun Kim;Eun-bi Shin;Iljung Lee;Heejung Kim;Kyo Chul Lee;Kyeong Min Kim;Joo Hyun Kang;Sang Moo Lim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.2
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    • pp.147-152
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    • 2021
  • C-11 Radiolabeled amino acid-based radiopharmaceuticals such as [11C]MET for brain tumor PET imaging have limitations due to their short half-life (20 min). F-18 radiolabeled amino acid derivatives have been developed to overcome for the short half-life, one of which is [18F]FET. Brain tumor imaging using [18F]FET showed high uptake in tumor region and no non-specific uptake in inflammatory tissue, which was useful in discriminating the difference between inflammation and tumor especially. In this study, [18F]FET was synthesized using an automatic synthesis module and quality tests were carried out including enantiomeric purity analysis with reference compounds. Radiochemical yield was 50.3 ± 4.9% (n=7, decay-corrected) with molar activity of 76 ± 17 GBq/mmol. The radiochemical purity of >99%. Enantiomeric purity of [18F]FET using chiral HPLC analysis showed >99%, which was confirmed by co-injection with the L-FET and D-FET authentic standards. [18F]FET was prepared with high radiochemical yield and molar activity including no racemate mixture.

Free vibration analysis of a laminated trapezoidal plate with GrF-PMC core and wavy CNT-reinforced face sheets

  • Yingqun Zhang;Qian Zhao;Qi Han;N. Bohlooli
    • Steel and Composite Structures
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    • v.48 no.3
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    • pp.275-291
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    • 2023
  • This paper has focused on presenting vibration analysis of trapezoidal sandwich plates with 3D-graphene foam reinforced polymer matrix composites (GrF-PMC) core and FG wavy CNT-reinforced face sheets. The porous graphene foam possessing 3D scaffold structures has been introduced into polymers for enhancing the overall stiffness of the composite structure. Also, 3D graphene foams can distribute uniformly or non-uniformly in the plate thickness direction. The effective Young's modulus, mass density and Poisson's ratio are predicted by the rule of mixture. In this study, the classical theory concerning the mechanical efficiency of a matrix embedding finite length fibers has been modified by introducing the tube-to-tube random contact, which explicitly accounts for the progressive reduction of the tubes' effective aspect ratio as the filler content increases. The First-order shear deformation theory of plate is utilized to establish governing partial differential equations and boundary conditions for trapezoidal plate. The governing equations together with related boundary conditions are discretized using a mapping-generalized differential quadrature (GDQ) method in spatial domain. Then natural frequencies of the trapezoidal sandwich plates are obtained using GDQ method. Validity of the current study is evaluated by comparing its numerical results with those available in the literature. It is explicated that 3D-GrF skeleton type and weight fraction, carbon nanotubes (CNTs) waviness and CNT aspect ratio can significantly affect the vibrational behavior of the sandwich structure. The plate's normalized natural frequency decreased and the straight carbon nanotube (w=0) reached the highest frequency by increasing the values of the waviness index (w).

Phase analysis of simulated nuclear fuel debris synthesized using UO2, Zr, and stainless steel and leaching behavior of the fission products and matrix elements

  • Ryutaro Tonna;Takayuki Sasaki;Yuji Kodama;Taishi Kobayashi;Daisuke Akiyama;Akira Kirishima;Nobuaki Sato;Yuta Kumagai;Ryoji Kusaka;Masayuki Watanabe
    • Nuclear Engineering and Technology
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    • v.55 no.4
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    • pp.1300-1309
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    • 2023
  • Simulated debris was synthesized using UO2, Zr, and stainless steel and a heat treatment method under inert or oxidizing conditions. The primary U solid phase of the debris synthesized at 1473 K under inert conditions was UO2, whereas a (U, Zr)O2 solid solution formed at 1873 K. Under oxidizing conditions, a mixture of U3O8 and (Fe, Cr)UO4 phases formed at 1473 K, whereas a (U, Zr)O2+x solid solution formed at 1873 K. The leaching behavior of the fission products from the simulated debris was evaluated using two methods: the irradiation method, for which fission products were produced via neutron irradiation, and the doping method, for which trace amounts of non-radioactive elements were doped into the debris. The dissolution behavior of U depended on the properties of the debris and aqueous solution for immersion. Cs, Sr, and Ba leached out regardless of the primary solid phases. The leaching of high-valence Eu and Ru ions was suppressed, possibly owing to their solid-solution reaction with or incorporation into the uranium compounds of the simulated debris.