• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.23 no.2
• /
• pp.191-198
• /
• 2010

This study investigated that the stress reduction of single edge cracked plates with patch repairs according to different type of patching such as material, size and thickness of patch and adhesive as well as single sided or double sided patches. As a numerical tool, the p-convergent partial layerwise model has been employed. The proposed model is formulated by assuming piecewise linear variation of in-plane displacement and a constant value of out-of-plane displacements across thickness. The integrals of Legendre polynomials are chosen to define displacement fields and Gauss-Lobatto numerical integration is implemented in order to directly obtain maximum values occurred at the nodal points of each layer without other extrapolation techniques. Also, total strain energy release rate method is adopted to obtain stress intensity factors. Numerical examples are presented not only to demonstrate the stress reduction effect in terms of non-dimensional stress intensity factor and deflection with respect to different type of patch repairs, but also the accuracy of proposed model.

• Journal of the Korea Concrete Institute
• /
• v.28 no.2
• /
• pp.141-148
• /
• 2016

This paper employed finite element method (FEM) to study the dynamic response of Steel Fiber-Reinforced Concrete(SFRC) panels subjected to impact loading by spherical projectiles. The material properties and non-linear stress-strain curves of SFRC were obtained by compression test and flexural test. Various parametric studies, such as the effect of fiber volume fraction and thickness of panels, are made and numerical analyses are compared with experiments conducted. It is shown that protective performance of concrete panels will be improved by adding steel fiber. Area loss rates and weight loss rates are decreased with increasing fiber volume fraction. Also, penetration modes can be expected by FEM, showing well agreement with experiment. Results can be applied for designing the protection of military structures and other facilities against high-velocity projectiles.

• Journal of the Korea Concrete Institute
• /
• v.28 no.4
• /
• pp.427-434
• /
• 2016

The purpose of this study is to propose a mixture proportioning approach based on the replacement level of natural sand for reducing $CO_2$ emissions from artificial lightweight aggregate concrete(LWAC) production. To assess the effect of natural sand on the reduction of $CO_2$ emissions and compressive strength of LWAC, a total of 379 specimens compiled from different sources were analyzed. Based on the non-linear regression analysis using the database and the previous mixture proportioning method proposed by Yang et al., simple equations were derived to determine the concrete mixture proportioning and the replacement level of natural sand for achieving the targeted performances(compressive strength, initial slump, air content, and $CO_2$ reduction ratio) of concrete. Furthermore, the proposed equations are practically applicable to straightforward determination of the $CO_2$ emissions from the provided mixture proportions of LWAC.

• Journal of Preventive Medicine and Public Health
• /
• v.31 no.2 s.61
• /
• pp.265-274
• /
• 1998

To investigate the change of nitric oxide(NO), copper, and zinc in serum on smoking and alcohol ingestion in young adults, this study was performed in a cross-sectional study in 127 healthy men in Korea who had HBsAg(-), HCVAb(-), and no symptomatic liver, heart, gastrointestinal, chronic diseases, and inflammatory sign(lower than 10,000 white blood cell count in CBC). At the men's entry into the study, blood samples were drawn from each subject and immediately centrifuged for analysis of NO, copper, and zinc. Each man completed a questionnaire that provided information on smoking, alcohol intake and present and past medical history NO was analyzed by HPLC(Green et al., 1982), copper and zinc by atomic absorption spectrophotometer with air-acetylene flame and total cholesterol(TC) by Spectrum EPX. Smoking(number of cigarettes per day and pack-year) and alcohol intake was grouped fertile. Copper was adjusted for age and zinc and for age and TC. NO, copper, and zinc on smoking and alcohol ingestion were analyzed in general linear models, respectively. NO, copper and zinc in serum did not show statistical differences between non-smoking and high-smoking group and no-alcohol intake and high-alcohol intake group. This study suggested that copper, zinc, and NO was not. good biological marker for early effect by smoking and alcohol intake in young adults. However, selection bias should be considered in evaluation of this result. A large prospective study will be needed in advance on usefulness of copper, zinc, and NO as a marker for risk factors and early change of atherosclerosis.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.5 no.5
• /
• pp.47-56
• /
• 2001

In order to assure the safety of NPP structures, margin of safety or conservatism is incorporated in each design step. Seismic risk evaluation of NPP structures is performed based on the realistic capacity and response of structure eliminated the safety margin and conservatism. In this study, the comparative study on the various evaluation methods of the inelastic energy absorption capacity was performed. The inelastic energy absorption capacity due to the nonlinear behavior of structures has significant effect on the results of seismic probabilistic risk assessment. And the comparison study of the HCLPF(high confidence of low probability of failure) values according to the inelastic energy absorption factors was performed. As a conclusion, the inelastic energy absorption factor of NPP containment structure is estimated about 1.5~1.75. It is essential to estimate the nonlinear behavior of structure and its ductility factor correctly for the seismic risk assessment.

• Journal of the Korea Society for Simulation
• /
• v.23 no.3
• /
• pp.19-25
• /
• 2014

Demand forecasting is the basis of management activities including marketing strategy. Especially, the demand of a part is remarkably important in supply chain management (SCM). In the fields of various industries, the part demand usually has the intermittent characteristic. The intermittent characteristic implies a phenomenon that there frequently occurs zero demands. In the intermittent demands, non-zero demands have large variance and their appearances also have stochastic nature. Accordingly, in the intermittent demand forecasting, it is inappropriate to apply the traditional time series models and/or cause-effect methods such as linear regression; they cannot describe the behaviors of intermittent demand. Markov bootstrap method was developed to forecast the intermittent demand. It assumes that first-order autocorrelation and independence of lead time demands. To release the assumption of independent lead time demands, this paper proposes a modified bootstrap method. The method produces the pseudo data having the characteristics of historical data approximately. A numerical example for real data will be provided as a case study.

• Journal of the Korean Society of Radiology
• /
• v.2 no.1
• /
• pp.23-29
• /
• 2008

The present study proposed a method that dissolves ultrasonographic images into multiple resolutions using wavelet conversion and a boundary detection filter and improves the quality of ultrasonographic images through boundary detection filtering. In order to reduce noises and strengthen edges, the proposed method adjusted selectivity coefficient by area step by step from a low resolution image obtained from wavelet converted images to a high resolution image and performed edge filtering in consideration of direction. Through this method, we generated a selective low pass filtering effect in areas except edges by decreasing the wavelet coefficient for pixels in spot areas, improved continuity by smoothing edges in the tangential direction, and enhanced contrast by thinning in the normal direction. Through an experiment, we compared the filtering method using a non linear anisotropic expansion model and the filtering method using wavelet contraction structure in single resolution.

• Korean journal of food and cookery science
• /
• v.30 no.4
• /
• pp.454-462
• /
• 2014

This study aimed at the optimization and development of rice snack by response surface methodology (RSM). The effect of rice soaking time and additional ratio of soybean milk on physicochemical properties and sensory evaluation of dried rice flour for non-fried snack was studied. After soaking for 0 to 12 days, Baekjinju rice was milled and then air-dried. A quadratic model was selected for weight, volume, hardness, taste and appearance. Two-factor interaction model was selected for expansibility, color and overall preference. A linear model was selected for yellowness and flavor. Weight, hardness and appearance were increased and decreased thereafter as rice soaking time increased, but the volume was reversed. Expansibility, color, taste and flavor were decreased as rice soaking time increased, but yellowness was reversed. Weight and overall preference decreased as additional ratio of soybean milk increased, but volume, expansibility and yellowness were reversed. Hardness, taste and appearance were increased after initial decrease as additional ratio of soybean milk increased, color and flavor were not changed by additional ratio of soybean milk. The optimum conditions of each factor were set to where the rice soaking time and additional ratio of soybean milk were at their minimum. Weight, volume, expansibility, yellowness, hardness, color, taste, flavor, appearance and overall preference were established at maximum level where the objective of the optimum was in level. Our data indicated the statistically predicted values of the highest desirability was 1.24 day of rice soaking time and 15.80% of additional ratio of soybean milk.

• Korean Journal of Clinical Pharmacy
• /
• v.28 no.1
• /
• pp.24-29
• /
• 2018

Background: Cyclosporine is an immunosuppressive agent used to treat and prevent graft versus host reaction (GVHR)-a complication associated with stem cell transplantation. This study aimed to develop a population pharmacokinetic model of cyclosporine and investigate factors affecting cyclosporine clearance in pediatric hematopoietic stem cell transplant patients. Methods: A total of 650 cyclosporine concentrations recorded in 65 patients who underwent hematopoietic stem cell transplantation were used. Data including age, sex, weight, height, body surface area (BSA), type of disease, chemotherapy before stem cell transplantation, type of donor, serum creatinine levels, total bilirubin concentration, hematocrit value, and type of concomitant anti-fungal agents and methylprednisolone used were retrospectively collected. Data related to cyclosporine dosage, administration time, and blood concentration were also collected. All data were analyzed using the non-linear mixed effect model; a two-compartment model with first-order elimination was used. Results: The population pharmacokinetic model of cyclosporine using the NONMEM program was as follows: $CL(L/h)=5.9{\times}(BSA/1.2)^{0.9}$, V2 (L) = 54.5, Q (L/h) = 3.5, V3 (L) = 1080.0, $k_a(h^{-1})=0.000377$. BSA was selected as a covariate of cyclosporine clearance, which increased with an increase in BSA. Conclusion: A population pharmacokinetic model for Korean pediatric hematopoietic stem cell transplant patients was developed, and the important factor affecting cyclosporine clearance was found to be BSA. The model might contribute to the development of the most appropriate dosing regimen for cyclosporine. Further studies on population pharmacokinetics should be carried out, prospectively targeting pediatric patients.

• Journal of the Korean Ceramic Society
• /
• v.34 no.1
• /
• pp.23-30
• /
• 1997

Semiconductive SrTiO3 ceramic bodies were prepared by conventional ceramic powder processes in-cluding sintering in a reducing atmosphere. Sodium or potassium ions were diffused from the surface of the sintered bodies into the inner region using thermal diffusion process at 800-120$0^{\circ}C$. The effects of such ther-mal treatments on the electrical and chemical characteristics of the grain boundaries were investigated. The presence of sodium or potassium ions at grain boundaries produces non-linear current-voltage behaviors, electrical boundary potential barriers of 0.1-0.2eV, and threshold voltages of 10-70V. The diffused ions form diffusion layers with thicknesses of 20-50nm near the grain boundaries, reducing the concentration of strontium and oxygen.