• Title/Summary/Keyword: Non-essential

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Effect of Essential and Non-essential Amino Acids, Taurine or Glycine Supplemented to Fertilization Medium on In Vitro Cleavage and Development of Bovine Oocytes Matured and Fertilized In Vitro (체외수정배양액내에 첨가된 필수 .비필수아미노산, Taurine 또는 Glycine이 소 난자의 분할 및 체외발육에 미치는 영향)

  • 이은송;이병천;황우석
    • Journal of Embryo Transfer
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    • v.10 no.2
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    • pp.131-138
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    • 1995
  • Essential and non-essential amino acids supplemented to culture medium stimulate mammalian embryo development in vitro. Amino acids such as glycine, taurine and alanine are concentrated in the lumen of oviduct and uterus and it can he thought that these amino acids may have physiological role on fertilization and embryo development. Our aim of this experiment was to investigate the effects of essential and non-essential amino acids, taurine or glycine supplemented to fertilization medium on the cleavage and subsequent in vitro development of bovine oocytes matured and fertilized in vitro. Immature oocytes were obtained from slaughtered Holstein cows and heifers and matured in TCM199 containing 10% fetal calf serum, 2.5 $\mu$g /mL of FSH and LH and 1 $\mu$g / mL of estradiol with granulosa cells in vitro. After maturation, oocytes were coincubated with sperm in fertilization medium supplemented with Minimum Essential Medium (MEM) essential and non-essential amino acids, taurine (3.75 mM) or glycine (10 mM) for 30 hours in vitro. Inseminated oocytes were cultured in synthetic oviduct fluid medium (SOEM) containing MEM essential, non-essential amino acids and 1 mM glutarnine up to 8 days after fertilization.Supplementation of fertilization medium with MEM essential and non-essential amino acids lowered significantly (p<0.05 and p<0.001) the cleavage rate after 30 hours of IVF (53.3%) and at Day 3 (62.7%: Day 0: the day of I VF) compared to control (64.3% and 77.3%, respectively). Subsequent developmental rates to morulae (Mo) and expanding blastocysts (ExBL) also significantly decreased (p<0.001 and p<0.05 for Mo and ExBL) when oocytes were coincubated with sperm in the medium containing MEM amino acids. Taurine added to fertilization medium have not increased the cleavage rate over the control, whereas glycine showed significantly lower (p<0.01) cleavage rate at Day 3 than that of taurine, but there was no significant difference in the developmental rates to Mo and ExBL of bovine embryos irrespective of the supplementation of taurine or glycine to fertilization medium. In conclusion, supplementation of fertilization medium with essential and non-essential amino acids, taurine or glycine has no beneficial effect on in vitro cleavage and development of bovine oocytes matured and fertilization in vitro.

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The Impact of Nature of Purchase and Purchase Utility on Purchase Intention According to Retailtainment (리테일테인먼트에 따라 구매특성과 구매효용이 구매의도에 미치는 영향)

  • Oh, Hyun-Seok;Cheon, Hongsik J.
    • Journal of Distribution Science
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    • v.16 no.12
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    • pp.57-68
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    • 2018
  • Purpose - The development of technologies lead the volume of sale on online market increase but an off-line shopping center is still a core component in the omni-channel strategy. It is generally thought that high-level retailtainment on brick and mortar store affects purchase intentions positively, but some previous studies dispute that and have reported that retailtainment does not affect purchase intentions. So we have studied the additional factors' effect - the nature of purchase and utility - with retailtainment. Research design, data, and methodology - There are 8 treatment groups which were assigned by the method of retailtainment (high vs. low), nature of purchase (essential vs. non-essential), and utility (acquisition vs. transaction). A total of 240 subjects (office workers = 163, 68%; undergraduates = 77, 32%; average age = 30s; female = 39%) were divided into groups and exposed to one of the eight scenarios. Participant's purchase intention was the dependent, and ANOVA and L-matrix were used to analyze for main and interactive effects between factors. Results - First, the main effect and interactive effect between retailtainment and the nature of purchase are significant. We also found that the contrast between essential and non-essential at low-level retailtainment is higher than that of high-level retailtainment. Second, in the case of retailtainment and utility, transaction utility under high-level retailtainment affects purchase intentions positively. Third, between the nature of the purchase and utility, the main effect of the nature of purchase and the interactive effect is significant, but the main effect of utility is not significant. In the case of non-essential goods, the purchase intention was high when transaction utility was provided but in the case of essential goods, acquisition utility increased purchase intentions. Finally, when transaction utility is given, purchase intentions of essential goods increase under low retailtainment, and the purchase intentions of non-essential goods increase under high retailtainment. Conclusions - When customers buy essential goods, discounts decrease purchase intentions. During the season for bargain sales, purchase intentions increase when retailtainment of essential goods is low, and retailtainment of non-essential goods is high.

On Rings Containing a Non-essential nil-Injective Maximal Left Ideal

  • Wei, Junchao;Qu, Yinchun
    • Kyungpook Mathematical Journal
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    • v.52 no.2
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    • pp.179-188
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    • 2012
  • We investigate in this paper rings containing a non-essential $nil$-injective maximal left ideal. We show that if R is a left MC2 ring containing a non-essential $nil$-injective maximal left ideal, then R is a left $nil$-injective ring. Using this result, some known results are extended.

Comparative analysis of amino acid contents of the fruiting bodies in Ganoderma spp. (영지버섯 균주별 자실체의 아미노산함량 비교 분석)

  • Cho, Jae-Han;Noh, Hyung-Jun;Kang, Don-Ho;Lee, Jee-Young;Lee, Min-Jung;Park, Hye-Sung;Sung, Gi-Ho;Jhune, Chang-Sung
    • Journal of Mushroom
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    • v.10 no.4
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    • pp.208-215
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    • 2012
  • Ingredient content for the general composition of essential amino acids and non-essential amino acids were analyzed by the fruiting bodies of Ganoderma sp. The results obtained are as followes. The ASI 7004 showed that high concentrations than other strains in essential amino acids(His, Ile, Leu, Phe, Thr, Val) and the non-essential amino acids(Ala, Ser, Gly). In addition, The ASI 7002 showed that high concentrations than other strains in essential amino acids(Lys) and the non-essential amino acids(Asp, Glu). ASI 7022 showed that high concentrations than other strains in essential amino acids(Met) and the non-essential amino acids(Pro). In General, contents of Amino acid was higher than Phellinus.

Technological importance and breadth of standard essential patents: A comparison between practicing and non-practicing entities for mobile telecommunication technologies

  • Yang, Sangoon;Jung, Taehyun
    • ETRI Journal
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    • v.42 no.5
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    • pp.734-747
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    • 2020
  • Using 23 867 standard essential patents claimed for three different wireless telecommunication standards (GSM, WCDMA, and LTE), this research examined the difference in technological importance and breadth of patents between practicing and non-practicing entities. We discovered that compared to manufacturers and service providers, organizations who do not appropriate innovation-derived profits directly from product or service markets tended to have relatively low-quality but broadly scoped technologies for the claimed standard essential patents. These relationships between the characteristics of inventions and the organizational types were consistently held across different generations of wireless standards as indicated by regressions run for each sample split by generation. Furthermore, the theory and policy implications of our results and arguments are presented herein.

Correction Method for Signal Boost-up or Drag-down Caused by Non-zero Mean Noise (Non-zero Mean Noise에 의한 Signal의 Boost-up 및 Drag-down을 Correction하기 위한 연구)

  • Im, Na-Ri;Kim, Il-Do;Choi, Byung-Sun;Park, Sahng-Gyu
    • Proceedings of the IEEK Conference
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    • 2007.07a
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    • pp.229-230
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    • 2007
  • 카메라 시스템에서 일반적인 Noise Reduction방법은 Noise간에 서로 Correlation이 없고 Independent한 White Noise이며, Zero Mean Noise라는 가정 하에 설계된 것이다. 본 논문에서는, 실제 Non-zero Mean Noise 현상을 규명하고, 이에 의해 발생한 Low Level Signal의 Boost-up 및 High Level Signal의 Drag-down을 Correction하여 화질을 개선하기 위한 방안을 제안한다.

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Elemental analysis of the liver, kidney, and intestine tissues from a Hodgson's bat (Myotis formosus tsuensis)

  • Yu, Hee Jeong;Kang, Jung-Hoon;Lee, Seungwoo;Choi, Yu Jung;Oh, Dayoung;Lim, Jong-Deock;Ryu, Doug-Young
    • Korean Journal of Veterinary Research
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    • v.56 no.1
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    • pp.51-52
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    • 2016
  • Hodgson's bats are critically endangered in South Korea. This study analyzed the concentrations of elements in liver, kidney, and intestine tissues from a Hodgson's bat found dead in the wild. The concentrations of essential elements followed the order Fe > Zn > Cu > Mn > Se in the three tissues. Hg was detected at the highest concentrations among the non-essential elements analyzed in the liver and kidney tissues, while As was the most highly concentrated non-essential element in the intestine. To the best of our knowledge, this is the first study of tissue element concentrations in Hodgson's bats.

Central Functions of Amino Acids for the Stress Response in Chicks

  • Yamane, H.;Kurauchi, I.;Denbow, D.M.;Furuse, Mitsuhiro
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.2
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    • pp.296-304
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    • 2009
  • The nutritional significance of essential amino acids, as well as non-essential amino acids, is well documented in poultry production with regards to growth performance and protein accretion. However, the function of amino acids in the stress response is still unclear. L-Pipecolic acid, a L-lysine metabolite in the brain, induced a hypnotic and sedative effect acting via the ${\gamma}$- aminobutyric acid receptors. L-Arginine also induced a sedative effect via its metabolism to L-ornithine. In addition, three-carbon nonessential amino acids like L-alanine, L-serine and L-cysteine also induced sedative effects. These facts suggest that the requirement for amino acids in both essential and non-essential types may require reconsideration to add the concept of stress amelioration in the future.

In-silico analysis of Lavender oil for Non-small cell lungcancer targeting ROS1

  • Bavya Chandrasekhar
    • Journal of Integrative Natural Science
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    • v.16 no.2
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    • pp.53-59
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    • 2023
  • Lavender oil is a prolonged history in ancient medicine and has a wide range of biological effects. The lavender essential oil has 50 different constituents that have different therapeutic significance. The compounds that are separated from essential oil can be used for the anticancer treatment of non-small cell lung cancer. ROS1 is one of the major targets for NSCLC. The compounds from lavender essential oil are separated through GC-MS. From 91 compounds the top compounds that are having high retention values are taken for Molecular docking study against the ROS1 target protein. The binding affinity and the docked pose for those compounds are studied. Later, the chemical reactivity of the compounds is studied by Density Functional Theory. The potent compounds must be validated by in vivo study.

Shape Function Modification for the Imposition of EFGM Essential Boundary Conditions (EFGM에서 필수경계조건 처리를 위한 형상함수 수정법)

  • Seok, Byeong-Ho;Song, Tae-Han;Im, Jang-Geun
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.3 s.174
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    • pp.803-809
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    • 2000
  • For the effective analysis of an engineering problem, meshless methods which require only positioning finite points without the element meshing recently have been proposed and being studied extensively. Meshless methods have difficulty in imposing essential boundary conditions directly, because non-interpolate shape functions originated from an approximation process are used. So some techniques, which are Lagrange multiplier method, modified variational principles and coupling with finite elements and so on, were introduced in order to impose essential boundary conditions. In spite of these methods, imposition of essential boundary conditions have still many problems like as non-positive definiteness, inaccuracy and negation of meshless characteristics. In this paper, we propose a new method which modifies shape function. Through numerical tests, convergence, accuracy and validity of this method are compared with the standard EFGM which uses Lagrange multiplier method or modified variational principles. According to this study, the proposed method shows the comparable accuracy and efficiency.