• Korean Chemical Engineering Research
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• v.45 no.2
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• pp.178-182
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• 2007

Non-aqueous supercapacitors by using activated C and $LiMn_2O_4$ as an active material in a positive electrode were prepared and characterized. From the cyclic voltammetry and AC impedance analysis, the capacitive effect by electric double layer of activated carbon and the faradic effect by intercalation/deintercalation of $Li^+$ ion were observed. Increasing the ratio of $LiMn_2O_4$, specific capacitances and energy densities of supercapacitor were increased. At the ratio of 0.86:0.14 ($LiMn_2O_4:C$), the maximum specific capacitance of 17.51 Wh/L and energy density of 23.83 F/cc were obtained, which were more than twice of those for a conventional electric double layer capacitor. Even after 1,000 charge/discharge cycle, the supercapacitor by using the electrode containing 14% of activated carbon and 86% of $LiMn_2O_4$ showed 60% better specific capacitance and energy density than that by using the electrode containing 100% activated carbon.

• Reproductive and Developmental Biology
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• v.32 no.4
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• pp.255-261
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• 2008

The early diagnosis of bovine pregnancy is an essential component of successful reproductive planning on farms, because lack of bovine pregnancy over the long term results in reproductive failure and low milk yield-the latter of which is a special concern on dairy farms. This study was designed to identify early pregnancy-specific whey proteins in bovine, by comparing milk samples collected from cattle during pregnancy (Days 30 and 50) and from non-pregnant cattle. In this study, differentially expressed proteins in five pregnant and five non-pregnant Holstein dairy cattle were investigated and compared, using proteomics analysis. The first dimension was applied to a pH $3.0{\sim}10.0$ strip, by loading a 2-mg milk protein sample. After the second-dimension separation was performed, the gels were stained with colloidal Coomassie brilliant blue. The stained gels were scanned and the images were analyzed, to detect variations in protein spots between non-pregnant and pregnant cattle milk protein spots, using ImageMaster, this was followed by analysis with MALDI TOF-MS. Analysis of the 2-DE gel image resulted in a total of approximately $500{\sim}600$ protein spots, of which 12 spots were differentially expressed, six spots were up-regulated, and four spots were down-regulated; two spots were identified as pregnancy-specific proteins. These proteins were identified as lactoferrin, NA-DH dehydrogenase subunit 2, albumin, serum albumin precursor and transferrin. Our results via 2-D PAGE analysis revealed composite profiles of several milk proteins related to early bovine pregnancy, implying the possible use of these milk proteins in the early detection of bovine pregnancy.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.58 no.4
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• pp.459-467
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• 2013

This study was conducted to investigate the effects of substituting whole barley flours on quality characteristics of noodles. Noodles were made with composite flour containing 20% whole barley flour of various hullless barley cultivars and the quality characteristics, ${\beta}$-glucan content and antioxidant characteristics were investigated. In amylogram characteristics, the initial pasting temperature and peak viscosity were increased, and setback was decreased in complex flour. Noodles containing barley flour had low lightness, yellowness and high redness compare to wheat noodle. Water absorption of cooked noodles was lower than wheat noodle. The value of swelling index was high in noodles containing non-waxy barley flour and low in noodles containing waxy barley flour. Hardness and gumminess of noodles were lower than wheat noodle. Noodles containing non-waxy barley had higher hardness, cohesiveness and gumminess than noodles containing waxy barley flour. Dahan, non-waxy barley cultivar showed similar characteristics with the wheat noodle. ${\beta}$-Glucan content and antioxidant activity were increased with adding barley flour. Cooked noodle had slightly high ${\beta}$-glucan content, low starch content and low antioxidant activity compared to value of uncooked noodle.

• Journal of the Korean earth science society
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• v.39 no.2
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• pp.131-138
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• 2018

The purpose of this study is to improve the quantitative precipitation estimation method based on satellite brightness temperature. The non-linear equation for rainfall estimation is improved by analysing precipitation cases around the Korean peninsula in summer. Radar reflectivity is adopted the CAPPI 1.5 and CMAX composite fields that provided by the Korea Meteorological Agency (KMA). In addition, the satellite data are used infrared, water vapor and visible channel measured from meteorological imager sensor mounted on the Chollian satellite. The improved algorithm is compared with the results of the A-E method and CRR analytic function. POD, FAR and CSI are 0.67, 0.76 and 0.21, respectively. The MAE and RMSE are 2.49 and 6.18 mm/h. As the quantitative error was reduced in comparison to A-E and qualitative accuracy increased in compare with CRR, the disadvantage of both algorithms are complemented. The method of estimating precipitation through a relational expression can be used for short-term forecasting because of allowing precipitation estimation in a short time without going through complicated algorithms.

• Journal of the Korea Concrete Institute
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• v.25 no.6
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• pp.631-639
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• 2013

Non-linear finite element analysis for newly developed precast concrete details for beam-to-column connection which can be used in moderate seismic region was carried out in this study. Developed precast system is based on composite structure and which have steel tube in column and steel plate in beam. Improving cracking strength of joint under reversed cyclic loading, joint area was casted with ECC (Engineering Cementitious Composites). Since this newly developed precast system have complex sectional properties and newly developed material, new analysis method should be developed. Using embedded elements and models of non-linear finite element analysis program ABAQUS previously tested specimens were successfully analyzed. Analysis results show comparatively accurate and conservative prediction. Using finite element model, effect of axial load magnitude and flexural strength ratio were investigated. Developed connection have optimized performance under axial load of 10~20% of compressive strength of column. Plastic hinge was successfully developed with flexural strength ratio greater than 1.2.

• The Korean Journal of Applied Statistics
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• v.26 no.2
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• pp.335-347
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• 2013

There are various types of real world signals. For example, an electrocardiogram(ECG) represents myocardium activities (contraction and relaxation) according to the beating of the heart. ECG can be expressed as the fluctuation of ampere ratings over time. A signal is a composite of various types of signals. An orchestra (which boasts a beautiful melody) consists of a variety of instruments with a unique frequency; subsequently, each sound is combined to form a perfect harmony. Various research on how to to decompose mixed stationary signals have been conducted. In the case of non-stationary signals, there is a limitation to use methodologies for stationary signals. Huang et al. (1998) proposed empirical mode decomposition(EMD) to deal with non-stationarity. EMD provides a data-driven approach to decompose a signal into intrinsic mode functions according to local oscillation through the identification of local extrema. However, due to the repeating process in the construction of envelopes, EMD algorithm is not efficient and not robust to a noise, and its computational complexity tends to increase as the size of a signal grows. In this research, we propose a new method to extract a local oscillation embedded in a signal by utilizing the second derivative.

• Composites Research
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• v.22 no.2
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• pp.43-48
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• 2009

For the practical use of improved interlaminar fracture toughness by interleaving carbon non-woven tissue (CNWT), intelaminar fracture toughnesses of CFRP laminates with CNWT having different weights were experimentally investigated. A suitable weight of interleaved CNWT in CFRP laminates was discussed with Mode I and Mode II tests. Mode I and Mode II interlaminar fracture toughnesses (GIC and GIIC) were obtained by DCB and ENF tests. Six kinds of specimens with CNWT were prepared. The weights of CNWT per square meter for six types of specimens are $8g/m^2,\;10g/m^2,\;12g/m^2,\;16g/m^2,\;20g/m^2$, and $24g/m^2$, respectively. The mean GIC and GIIC values of six kinds of specimens were not substantially different from one another. Compared with the CFRP specimen, the mean GIC values of six kinds of specimens were slightly decreased. But the mean GIIC values increased tremendously at least twice by interleaving CNWT. It seems that there is no interrelationship between the interlaminar fracture toughnesses (GIC and GIIC) and the interleaving CNWT weights. Consequently, it would be desirable to use the CNWT of $8g/m^2$ among the six kinds of CNWTs to take advantage of the interlaminar fracture toughness improved by interleaving CNWT, because the CNWT of $8g/m^2$ is a lightweight and low-priced material.

• Korean Journal of Radiology
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• v.22 no.3
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• pp.324-333
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• 2021

Objective: The clinical course of an individual patient with heart failure is unpredictable with left ventricle ejection fraction (LVEF) only. We aimed to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived myocardial fibrosis extent and to determine the cutoff value for event-free survival in patients with non-ischemic cardiomyopathy (NICM) who had severely reduced LVEF. Materials and Methods: Our prospective cohort study included 78 NICM patients with significantly reduced LV systolic function (LVEF < 35%). CMR images were analyzed for the presence and extent of late gadolinium enhancement (LGE). The primary outcome was major adverse cardiac events (MACEs), defined as a composite of cardiac death, heart transplantation, implantable cardioverter-defibrillator discharge for major arrhythmia, and hospitalization for congestive heart failure within 5 years after enrollment. Results: A total of 80.8% (n = 63) of enrolled patients had LGE, with the median LVEF of 25.4% (19.8-32.4%). The extent of myocardial scarring was significantly higher in patients who experienced MACE than in those without any cardiac events (22.0 [5.5-46.1] %LV vs. 6.7 [0-17.1] %LV, respectively, p = 0.008). During follow-up, 51.4% of patients with LGE ≥ 12.0 %LV experienced MACE, along with 20.9% of those with LGE ≤ 12.0 %LV (log-rank p = 0.001). According to multivariate analysis, LGE extent more than 12.0 %LV was independently associated with MACE (adjusted hazard ratio, 6.71; 95% confidence interval, 2.54-17.74; p < 0.001). Conclusion: In NICM patients with significantly reduced LV systolic function, the extent of LGE is a strong predictor for long-term adverse cardiac outcomes. Event-free survival was well discriminated with an LGE cutoff value of 12.0 %LV in these patients.

• Korean Circulation Journal
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• v.52 no.4
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• pp.304-319
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• 2022

Background and Objectives: De-escalation of dual-antiplatelet therapy through dose reduction of prasugrel improved net adverse clinical events (NACEs) after acute coronary syndrome (ACS), mainly through the reduction of bleeding without an increase in ischemic outcomes. Whether the benefits of de-escalation are sustained in highly thrombotic conditions such as ST-elevation myocardial infarction (STEMI) is unknown. We aimed to assess the efficacy and safety of de-escalation therapy in patients with STEMI or non-ST-segment elevation ACS (NSTE-ACS). Methods: This is a pre-specified subgroup analysis of the HOST-REDUCE-POLYTECH-ACS trial. ACS patients were randomized to prasugrel de-escalation (5 mg daily) or conventional dose (10 mg daily) at 1-month post-percutaneous coronary intervention. The primary endpoint was a NACE, defined as a composite of all-cause death, non-fatal myocardial infarction, stent thrombosis, clinically driven revascularization, stroke, and bleeding events of grade ≥2 Bleeding Academic Research Consortium (BARC) criteria at 1 year. Results: Among 2,338 patients included in the randomization, 326 patients were diagnosed with STEMI. In patients with NSTE-ACS, the risk of the primary endpoint was significantly reduced with de-escalation (hazard ratio [HR], 0.65; 95% confidence interval [CI], 0.48-0.89; p=0.006 for de-escalation vs. conventional), mainly driven by a reduced bleeding. However, in those with STEMI, there was no difference in the occurrence of the primary outcome (HR, 1.04; 95% CI, 0.48-2.26; p=0.915; p for interaction=0.271). Conclusions: Prasugrel dose de-escalation reduced the rate of NACE and bleeding, without increasing the rate of ischemic events in NSTE-ACS patients but not in STEMI patients.

• Korean Circulation Journal
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• v.52 no.4
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• pp.324-337
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• 2022

Background and Objectives: Identifying patients with high bleeding risk (HBR) is important when making decisions for antiplatelet therapy strategy. This study evaluated the impact of ticagrelor monotherapy after 3-month dual antiplatelet therapy (DAPT) according to HBR in acute coronary syndrome (ACS) patients treated with drug eluting stents (DESs). Methods: In this post-hoc analysis of the TICO trial, HBR was defined by 2 approaches: meeting Academic Research Consortium for HBR (ARC-HBR) criteria or Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent DAPT (PRECISE-DAPT) score ≥25. The primary outcome was a 3-12 months net adverse clinical event (composite of major bleeding and adverse cardiac and cerebrovascular events). Results: Of the 2,980 patients without adverse events during the first 3 months after DES implantation, 453 (15.2%) were HBR by ARC-HBR criteria and 504 (16.9%) were HBR by PRECISE-DAPT score. The primary outcome rate was higher in HBR versus non-HBR patients (by ARC-HBR criteria: hazard ratio [HR], 2.87; 95% confidence interval [CI], 1.76-4.69; p<0.001; by PRECISE-DAPT score: HR, 3.09; 95% CI, 1.92-4.98; p<0.001). Ticagrelor monotherapy after 3-month DAPT was associated with lower primary outcome rate than ticagrelor-based 12-month DAPT regardless of HBR by ARC-HBR criteria, with similar magnitudes of therapy effect for HBR and non-HBR patients (p-interaction=0.400). Results were consistent by PRECISE-DAPT score (p-interaction=0.178). Conclusions: In ACS patients treated with DESs, ticagrelor monotherapy after 3-month DAPT was associated with lower rate of adverse clinical outcomes regardless of HBR, with similar magnitudes of therapy effect between HBR and non-HBR.