• Title/Summary/Keyword: Non-Invasive

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Ring type non-invasive glucose sensor (민감도가 향상된 링 형태의 비 침습식 혈당 센서)

  • Lee, Ki-Hyuck;Lee, Kook-Joo;Lee, Dong-Ho;Kim, Moon-Il;Park, Gil-Hong
    • Journal of IKEEE
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    • v.11 no.4
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    • pp.293-296
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    • 2007
  • A novel sensitive and non-invasive ring-type glucose probe was designed and measured. The magnitude and phase of return loss change with different concentration of the glucose solution inside the loop structure. Ring type probe is more advantageous than open ended probe to measure electrical characteristics under the skin. The maximum difference of return loss was 0.94 for the concentration difference of 0% and 20% at 285MHz and more sensitive in low frequency.

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Non-Invasive Measurement of Shear Rates of Pulsating Pipe Flow Using Echo PIV (에코 PIV를 이용한 맥동 유동에서의 in vitro 전단률 측정 연구)

  • Kim, Hyoung-Bum;Chung, In-Young
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.12
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    • pp.1567-1572
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    • 2004
  • Although accurate measurement of velocity profiles, multiple velocity vectors, and shear stress in arteries is important, there is still no easy method to obtain such information in vivo. This study shows the utility of combining ultrasound contrast imaging with particle image velocimetry (PIV) for non-invasive measurement of velocity vectors. The steady flow analytical solution and optical PIV measurements (for pulsatile flow) were used for comparison. When compared to the analytical solution, both echo PIV and optical PIV resolved the steady velocity profile well. Error in shear rate as measured by echo PIV (8%) was comparable to the error of optical PIV (6.5%). In pulsatile flow, echo PIV velocity profiles agreed well with optical PIV profiles. Echo PIV followed the general profile of pulsatile shear stress across the artery but underestimated wall shear at certain time points. These studies indicate that echo PIV is a promising technique for the non-invasive measurement of velocity profiles and shear stress.

Monitoring Ion Energy Distribution in Capacitively Coupled Plasmas Using Non-invasive Radio-Frequency Voltage Measurements

  • Choi, Myung-Sun;Lee, Seok-Hwan;Jang, Yunchang;Ryu, Sangwon;Kim, Gon-Ho
    • Applied Science and Convergence Technology
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    • v.23 no.6
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    • pp.357-365
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    • 2014
  • A non-invasive method for ion energy distribution measurement at a RF biased surface is proposed for monitoring the property of ion bombardments in capacitively coupled plasma sources. To obtain the ion energy distribution, the measured electrode voltage is analyzed based on the circuit model which is developed with the linearized sheath capacitance on the assumption that the RF driven sheath behaves like a simple diode for a bias power whose frequency is much lower than the ion plasma frequency. The method is verified by comparing the ion energy distribution function obtained from the proposed model with the experimental result taken from the ion energy analyzer in a dual cathode capacitively coupled plasma source driven by a 100 MHz source power and a 400 kHz bias power.

A Study on the circuit design and measurement method for the measurement of active points on skin (피부 활성점 측정을 위한 회로설계 및 측정방법연구)

  • Kim, Min Soo;Cho, Young Chang
    • Journal of IKEEE
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    • v.24 no.3
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    • pp.713-718
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    • 2020
  • The method of measuring skin active points is a technique for obtaining a lot of biometric information because it is measured with convenience, low cost and non-invasive methods. In this paper, we used in a three electrode measure method that has the advantage of measuring the impedance of the APs under the skin. The impedance measuring method is well illustrated by a simple model of an equivalent electrical circuit that correlates well with experimental results. The characteristic frequencies of APs are about 15-30HZ higher than that of surrounding skin and the values of measured reactance are about 35-77KΩ smaller. This technology analyzed accurately and objectively the reactance and characteristic frequency of APs and the surrounding skin using a non-invasive measuring system.

Simple Assessment of Taxonomic Status and Genetic Diversity of Korean Long-Tailed Goral (Naemorhedus caudatus) Based on Partial Mitochondrial Cytochrome b Gene Using Non-Invasive Fecal Samples

  • Kim, Baek-Jun
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.2 no.1
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    • pp.32-41
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    • 2021
  • South Korea presently harbors less than 800 long-tailed gorals (Naemorhedus caudatus), an endangered species. I report for the first time on the taxonomic status and genetic diversity of the Korean species using non-invasive fecal sampling based on mitochondrial cytochrome b gene sequence analyses. To determine the taxonomic status of this species, I reconstructed a consensus neighbor-joining tree and generated a minimum spanning network combining haplotype sequences obtained from feces with a new goral-specific primer set developed using known sequences of the Korean goral and related species (e.g., Russian goral, Chinese goral, Himalayan goral, Japanese serow, etc.). I also examined the genetic diversity of this species. The Korean goral showed only three different haplotypes. The phylogenetic tree and parsimony haplotype network revealed a single cluster of Korean and Russian gorals, separate from related species. Generally, the Korean goral has a relatively low genetic diversity compared with that of other ungulate species (e.g., moose and red deer). I preliminarily showcased the application of non-invasive fecal sampling to the study of genetic characteristics, including the taxonomic status and genetic diversity of gorals, based on mitochondrial DNA. More phylogenetic studies are necessary to ensure the conservation of goral populations throughout South Korea.

Dental characteristics on panoramic radiographs as parameters for non-invasive age estimation: a pilot study

  • Harin Cheong;Akiko Kumagai;Sehyun Oh;Sang-Seob Lee
    • Anatomy and Cell Biology
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    • v.56 no.4
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    • pp.474-481
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    • 2023
  • The dental characteristics created by acquired dental treatments can be used as age estimators. This pilot study aimed to analyze the correlation between the number of teeth observed for dental characteristics and chronological age and to develop new non-invasive age estimation models. Dental features on panoramic radiographs (420 radiographs of subjects aged 20-89 years) were classified and coded. The correlation between the number of teeth for each selected code (codes V, X, T, F, P, and L) and age was observed, and multiple regression was performed to analyze the relationship between them. Eleven regression models with various combinations of dental sextants were presented. The model with the data from both sides of the posterior teeth on both jaws showed the best performance (root mean square error of 14.78 years and an adjusted R2 of 0.461). The model with all teeth was the second-best. Based on these results, we confirmed statistically significant correlations between certain dental features and chronological age. We also observed that some regression models performed sufficiently well to be used as adjunctive methods in forensic practice. These results provide valuable information for the design and performance of future full-scale studies.

Species and Sex Identification of the Korean Goral (Nemorhaedus caudatus) by Molecular Analysis of Non-invasive Samples

  • Kim, Baek Jun;Lee, Yun-Sun;An, Jung-hwa;Park, Han-Chan;Okumura, Hideo;Lee, Hang;Min, Mi-Sook
    • Molecules and Cells
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    • v.26 no.3
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    • pp.314-318
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    • 2008
  • Korean long-tailed goral (Nemorhaedus caudatus) is one of the most endangered species in South Korea. However, detailed species distribution and sex ratio data on the elusive goral are still lacking due to difficulty of identification of the species and sex in the field. The primary aim of this study was to develop an economical PCR-RFLP method to identify species using invasive or non-invasive samples from five Korean ungulates: goral (N. caudatus), roe deer (Capreolus pygargus), feral goat (Capra hircus), water deer (Hydropotes inermis) and musk deer (Moschus moschiferus). The secondary aim was to find more efficient molecular sexing techniques that may be applied to invasive or non-invasive samples of ungulate species. We successfully utilized PCR-RFLP of partial mitochondrial cytochrome b gene (376 bp) for species identification, and sex-specific amplification of ZFX/Y and AMELX/Y genes for sexing. Three species (goral, goat and water deer) showed distinctive band patterns by using three restriction enzymes (Xbal, Stul or Sspl). Three different sexing primer sets (LGL331/335 for ZFX/Y gene; SE47/48 or SE47/53 for AMELX/Y gene) produced sex-specific band patterns in goral, goat and roe deer. Our results suggest that the molecular analyses of non-invasive samples might provide us with potential tools for the further genetic and ecological study of Korean goral and related species.

The Controversy Regarding the Optimal Management of Chronic Low Back Pain: Interventional vs. Medical Treatment (만성요통의 적정 치료를 둘러싼 논란: 중재적 치료 대 보존적 치료)

  • Kwon, O-Hyun
    • Annals of Clinical Neurophysiology
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    • v.12 no.1
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    • pp.1-2
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    • 2010
  • Chronic non-specific low back pain (CLBP) is one of the major health problems casting substantial amount of economic expenses and negative impact on quality of life onto an individual as well as society. On contrary to public familiarity, the ways of management of CLBP are diverse and there is yet no general consensus about which approach is better than others or to whom the specific management should be applied. Some hold the negative point of view on the efficacy of the invasive maneuver such as epidural injection because there is no controlled clinical trial (RCT) yielding better long term outcome of those invasive managements over conservative ones. But the experts of interventional or surgical treatment stress the methodological difficulty in performing RCT and assert that those invasive treatments can bring the prompt and complete resolution of low back pain and restoration of function in appropriately selected cases. These seemingly opposite views on the invasive management on CLBP are rather complimentary each other than to be contradictory.

Clinical Characteristics of Cervical and Thoracic Radiculopathies: Non-Invasive Interventional Therapy (목 및 가슴신경뿌리병증의 임상적 고찰: 비침습적 중재시술치료)

  • Roh, Hakjae;Lee, Sang-Heon;Kim, Byung-Jo
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.83-97
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    • 2008
  • Cervical and thoracic radiculopathies are among the most common causes of neck pain. The most common causes are cervical disc herniation and cervical spondylosis in patients with cervical radiculopathy, and diabetes mellitus and thoracic disc herniation in thoracic radiculopathy. A thorough history, physical examination, and testing that includes electrodiagnostic examination and imaging studies may distinguish radiculopathy from other pain sources. Although various electrodiagnostic examinations may help evaluate radiculopathy, needle electromyography is the most important, sensitive, and specific method. Outcome studies of conservative treatments have shown varying results and have not been well controlled or systematic. When legitimate incapacitating symptoms continue despite conservative treatment attempts, more invasive spinal procedures and intradiscal treatment may be appropriate. Surgery has been shown to have excellent clinical outcomes in patients with disc extrusion and neurological deficits. However, patients with minimal disc herniation have fair or poor surgical outcomes. In addition, conventional open disc surgery entails various inadvertent surgical related risks. Although there has not yet been a non-surgical interventional procedure developed with the therapeutic efficacy of open surgery, conservative procedures can offer substantial benefits, are less invasive, and avoid surgical complications. While more invasive procedures may be appropriate when conservative treatment fails, prospective studies evaluating cervical and thoracic radiculopathies treatment options would help guide practitioners toward optimally cost-effective patient evaluation and care.

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Evaluation of the Atlas Helicobacter pylori Stool Antigen Test for Diagnosis of Infection in Adult Patients

  • Osman, Hussein Ali;Hasan, Habsah;Suppian, Rapeah;Bahar, Norhaniza;Che Hussin, Nurzam Suhaila;Rahim, Amry Abdul;Hassan, Syed;Andee, Dzulkarnaen Zakaria;Zilfalil, Bin-Alwi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5245-5247
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    • 2014
  • Background: Helicobacter pylori (H.pylori) is one of the most important causes of dyspepsia and gastric cancer and diagnosis can be made by invasive or non-invasive methods. The Atlas Helicobacter pylori antigen test is a new rapid non-invasive method which is simple to conduct. The aim of this study was to determine its sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy. Materials and Methods: This prospective study was conducted between July 2012 and December 2013. Stool samples of 59 dyspeptic patients who underwent upper endoscopy were evaluated for H. pylori stool antigen. Results: From the 59 patients who participated in this study, there were 36 (61%) males and 23 (39%) females. H. pylori was diagnosed in 24 (40.7%) gastric biopsies, 22 (91.7 %) of these being positive for the Atlas H. pylori antigen test. The sensitivity, specificity, PPV, NPV and accuracy were 91.7%, 100%, 100%, 94.6% and 96.6% respectively. Conclusions: The Atlas H. pylori antigen test is a new non-invasive method which is simple to perform and avails reliable results in a few minutes. Thus it can be the best option for the diagnosis of H. pylori infection due to its high sensitivity and specificity.