• Title/Summary/Keyword: Non-Dominant

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Improved Cell Viability of Lactobacillus crispatus KLB46 by Stress Adaptation (Lactobacillus crispatus KLB46의 스트레스 전처리시 열 내성 증진효과)

  • Kwak, Dae-Yung;Kang, Chang-Ho;Jeon, HanEul;So, Jae-Seong
    • KSBB Journal
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    • v.29 no.2
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    • pp.81-86
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    • 2014
  • Lactobacilli, the dominant species of microorganisms in the vaginal flora of healthy women, play important roles to prevent bacterial vaginosis and other sexually transmitted diseases. In this study, we carried out studies on stress adaptation prior to various stress treatment. We found that heat or salt adapted KLB46 showed higher cell viability than non adapted upon heat stress at $60^{\circ}C$ for 20 min. When chloramphenicol was added during the adaptation process, heat tolerance was abolished. This result suggested that de novo protein synthesis was essential during adaptation.

Electromyographic Analysis of Biceps during Provocative Tests

  • Lee Young-Soo;Shin Dong-Bae
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 1999.03a
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    • pp.3-4
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    • 1999
  • The electromyographic activity of four muscles of biceps, rotator cuffs (supraspinatus, infraspinatus and subscapularis) was measured from the non-dominant shoulders of 12 volunteers during six methods of provocative test for the biceps pathology. Any method of provocative test can not isolates the biceps activity prominently compared to the other rotator cuff muscles. But the Speed test can more isolates the activity of biceps than the other tests. Based upon this study, we think that the O'Brien's test is not a provocative maneuver by which the pain reproduced is not associated with the tension generated within the biceps tendon.

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Molecular Pathogenesis of Spinocerebellar Ataxia Type 1 Disease

  • Kang, Seongman;Hong, Sunghoi
    • Molecules and Cells
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    • v.27 no.6
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    • pp.621-627
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    • 2009
  • Spinocerebellar ataxia type 1 (SCA1) is an autosomal-dominant neurodegenerative disorder characterized by ataxia and progressive motor deterioration. SCA1 is associated with an elongated polyglutamine tract in ataxin-1, the SCA1 gene product. As summarized in this review, recent studies have clarified the molecular mechanisms of SCA1 pathogenesis and provided direction for future therapeutic approaches. The nucleus is the subcellular site where misfolded mutant ataxin-1 acts to cause SCA1 disease in the cerebellum. The role of these nuclear aggregates is the subject of intensive study. Additional proteins have been identified, whose conformational alterations occurring through interactions with the polyglutamine tract itself or non-polyglutamine regions in ataxin-1 are the cause of SCA-1 cytotoxicity. Therapeutic hope comes from the observations concerning the reduction of nuclear aggregation and alleviation of the pathogenic phenotype by the application of potent inhibitors and RNA interference.

The Effects of Transcutaneous Electrical Nerve Stimulation on Sympathetic Nerve Activity in Delayed Onset Muscle Soreness (경피신경전기자극이 지연성근육통의 교감신경활동에 미치는 영향)

  • Park, Jang-Sung
    • The Journal of Korean Physical Therapy
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    • v.14 no.1
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    • pp.109-115
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    • 2002
  • This study conducts eccentric exercise ti non-dominant elbow flexor of 20 persons in order to examine the effects of transcutaneous electric nerve stimulation on sympathetic nerve activity in delayed onset muscle soreness, induces delayed onset muscle soreness, divides them into 10 persons respectively as experimental and control groups. And a stimulation for 2 min. with 100 pps is given to elbow flexor after repeated three times of 10 minutes rest, temperature, blood pressure and pulse are measured and as a result of two-way ANOVA, change of temperature didn't show a significant difference according to the elapse of times(p>0.05) and systolic pressure and pulses in showed a significant difference between experimental and control groups(p<0.05). These results suggest that transcutaneous electrical nerve stimulation has a direct or indirect influence on sympathetic nerve activity in delayed onset muscle soreness under a restricted condition of electrical stimulation.

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A Model of the Operator Cognitive Behaviors During the Steam Generator Tube Rupture Accident at a Nuclear Power Plant

  • Mun, J.H.;Kang, C.S.
    • Nuclear Engineering and Technology
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    • v.28 no.5
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    • pp.467-481
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    • 1996
  • An integrated framework of modeling the human operator cognitive behavior during nuclear power plant accident scenarios is presented. It incorporates both plant and operator models. The basic structure of the operator model is similar to that of existing cognitive models, however, this model differs from those existing ones largely in too aspects. First, using frame and membership function, the pattern matching behavior, which is identified as the dominant cognitive process of operators responding to an accident sequence, is explicitly implemented in this model. Second, the non-task-related human cognitive activities like effect of stress and cognitive biases such as confirmation bias and availability bias, are also considered. A computer code, OPEC is assembled to simulate this framework and is actually applied to an SGTR sequence, and the resultant simulated behaviors of operator are obtained.

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LARGE EDDY SIMULATION OF FLOW AND MASS EXCHANGE PROCESSES BETWEEN A CHANNEL AND AN OPEN CAVITY (LES를 이용한 열린 공동 유동과 공동 내 물질 확산의 수치적 모사)

  • Chang K.S.;Park S.O.;Constantinescu G.
    • 한국전산유체공학회:학술대회논문집
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    • 2005.10a
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    • pp.239-243
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    • 2005
  • Fully three-dimensional Large Eddy Simulation calculations of the flow past 2D cavity are conducted to study the purging of neutrally buoyant or dense miscible contaminants introduced instantaneously inside the cavity. The length to depth ratio(L/D) is 2 and Reynolds number based on the depth is 3,360. Fully developed turbulent inflow are fed at the inlet from precursor simulation of channel flow. Mean flow pattern and unsteady features are investigated based on the experimental data of Pereira and Sousa. From the study of mass exchange processes, it is found that the mechanism of removal of the contaminant is very different between the non-buoyant and buoyant cases. In the buoyant case, internal wave motion which interacts with a strong cavity vortex is dominant in the ejection mechanism of the contaminants.

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Burr and Shape Distortion Micro-Grooving of Non-Ferrous Metals Using a Diamond Tool

  • Ahn, Jung-Hwan;Lim, Han-Seok;Son, Seong-Min
    • Journal of Mechanical Science and Technology
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    • v.14 no.11
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    • pp.1244-1249
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    • 2000
  • Burr and shape distortion are two main problems in micro-grooving. In this study, a simplified model is proposed based on large thrust force due to the tool edge radius. Experiments are conducted with a single crystal diamond tool on a 3-axis snaper-like machine varying the depth of cuts, and groove angles on brass, aluminum and OFHC. Experiments have shown that the thrust force becomes a dominant variable in burr generation compared to the principal force when the depth of cut is less than 2${\mu}m$. And fewer burrs develop on more brittle materials. Shape distortion is significant only when the groove angle is small and the depth of cut is larger than 30 ${\mu}m$.

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자동회귀-이동평균(ARMA) 모델에의한 초음파 진동 절삭 공정의 해석

  • 최인휴;김정두
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1993.04b
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    • pp.160-165
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    • 1993
  • The cutting mechanism of ultrasonic vibration machining is characterized as two phases, that is an impact at the cutting edge and a reduction of cutting force due to non-contact interval between tool and workpiece. In this paper, in order to identfy cutting dynamics of a system with ultrasonically vibrated cutting tool, an ARMA modelling is performed on experimental cutting force signals which have a dominant effect on cutting dynamics. The aim of this study is, through Dynamic Data System methodology, to find the inherent characteristics of an ultrasonic vibration cutting process by considering natural frequencyand damping coefficient. Surface roughness and stability of cutting process under ultrasonic vibration are also considered

A Study on the Expressivity of Covering and Exposing of Architecture Surface after Modern Architecture - Focused on the Tectonic Concept through Semper's Theory "Dressing" - (근·현대 건축표면의 가림과 드러냄의 표현성에 관한 연구 - 젬퍼의 피복론을 통한 텍토닉개념을 중심으로 -)

  • Oh, Sang-Eun
    • Korean Institute of Interior Design Journal
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    • v.23 no.3
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    • pp.29-38
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    • 2014
  • This paper is to analysis covering and exposing elements through surface in the spirit of the time through the meaning of relationship between structure and symbol(ornament) in the theory of dressing of Gottfrid Semper. In other words, The purpose is to illuminate how complementary tectonic between structure and symbolic of an architecture surface is expressed in accordance with the biased required conditions relating with the paradigm of the era. The advancement of the new method of tectonic and the new aesthetic taste have a deep relation with the reconsidering the dichotomy classification discussing a dominant position between structure and symbol(ornament). Expression of surface representing the era comes across the combined interpretation of technology, structure, and the non-physical culture's art of the community and the era.

Sensitivity of the $217Plus^{TM}$ System Model to Failure Causes (고장요인들에 대한 $217Plus^{TM}$ 시스템 모형의 민감도)

  • Jeon, Tae-Bo
    • Journal of Applied Reliability
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    • v.11 no.4
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    • pp.387-398
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    • 2011
  • $217Plus^{TM}$, a newly developed as a surrogate of the MIL-HDBK-217, may be widely applied for reliability predictions of electronic systems. In this study, we performed sensitivity study of the $217Plus^{TM}$ system model to various parameters. Specific attention was put to logistics model and its behavior has been examined in terms of non-component failure causes. We first briefly explained the $217Plus^{TM}$ methodology with system level failure rate evaluation. We then applied experimental designs with several failure causes as factors. We used an orthogonal array with three levels of each parameter. Our results indicate that cannot duplicate, induced, and wear-out causes have dominant effects on the system failures and design, parts, and system management have much less but a little strong effects. The results in this study not only figure out the behavior of the predicted failure rate as functions of failure causes but provide meaningful guidelines for practical applications.