• Physical Therapy Korea
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• v.15 no.4
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• pp.70-79
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• 2008

The purpose of this study was to find out the effects of electroencephalograph (EEG) power and coherence on cognitive function in normal elderly, non-demented elderly with mild cognitive impairment, and demented elderly during working cognition tasks. Forty elderly women (19 demented elderly, 10 non-demented elderly with mild cognitive impairment, 11 norma1 elderly) participated in this study, All subjects performed working cognition tasks with Raven's CPM while EEG signal was recorded, EEGs were measured continuously at rest and during the working cognition task. EEG power and coherence was computed over 21 channels: right and left frontal, central, parietal, temporal and occipital region. We found that there were more correct answers among normal elderly women than in other groups Owing the working cognition task, ${\Theta}$ wave at Fp1, Fp2 and F8, a wave at Fp2, ${\beta}$ wave at Fp1, Fp2. F4 and F8 of the frontal region was increased significantly in the demented elderly group. On the other hand. ${\Theta}$ wave at Fp1, Fp2 and F7, ${\beta}$ wave at Fp1, Fp2, F3 and F7 of the frontal region was increased significantly in the group of non-demented elderly with mild cognitive impairment. In contrast. in the normal elderly group, all of the ${\Theta}$ wave and ${\beta}$ wave at Fp1, Fp2, F3, F4, F7 and F8 of the frontal region (except ${\beta}$ wave at F3) was increased significantly, These results suggest that the nerves in prefrontal and right hemisphere regions were most active in the demented elderly group during problem solving, and the nerves in the prefrontal and left hemisphere lobe were most active in the group of non-demented elderly with mild cognitive impairment. In contrast, me majority of nerves in the frontal region were active in the normal elderly group.

• Smart Media Journal
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• v.13 no.10
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• pp.28-34
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• 2024

Alzheimer's disease is a form of dementia that can be managed by identifying the disease in its initial phases. In recent times, numerous computer-aided diagnostic techniques utilizing magnetic resonance imaging (MRI) have demonstrated promising outcomes in the categorization of Alzheimer's disease (AD). The OASIS MRI dataset was utilized which has 80,000 brain MRI images. It is suggested to resample this dataset as it is highly imbalanced and posed a challenge in preventing bias toward majority class while employing the convolution neural network (CNN) model for classification. This paper examines and extracts patterns and features of 461 patients taken from the OASIS dataset. The research has aimed at utilizing the Base Model of EfficientNetV2B0 with custom classification layers, and simplified custom CNN model, also exploring Multi-class classification across four distinct classes: Non-Demented, Very Mild Demented, Mild Demented, Moderate Demented in addition to binary classification as Non-Demented and treating other classes as demented. Furthermore, different dataset sizes were experimented with 5,000 and 20,000 for each class to be discussed in this paper. The experiment results indicate that EfficientNetV2B0 achieved the accuracy of 98% in binary classification, 99% in multiclass. Whereas custom sequential CNN model in multiclass classification presents the accuracy of 96% for 20,000 dataset size and 98% for 80,000 dataset size.

• Korean Journal of Psychosomatic Medicine
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• v.21 no.2
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• pp.140-146
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• 2013

Objectives: We compared the characteristics of the pain threshold and pain experience between demented group and non-demented group. Methods: This study was part of Gangwon projects for early detection of dementia in 2010. We recruited 8302 local resident ages over 65 years old. Of theses, 1259 people who scored low MMSE were selected and 365 of them completed CERAD-K(Consortium to Establish a Registry for Alzheimer's disease). Finally, 90 in non-demented group and 57 in demented group(mild to moderate Alzheimer's disease) were analyzed. Pain threshold was experimentally measured by pressure algometer and we investigated the pain experience, by Brief pain inventory (BPI), a self-report test. Results: In the demographic characteristics, there are more female, higher ages, lower education in the demented group. There was no significant difference between the two groups in the pain threshold. On the BPI results, 'shoulder pain', 'the number of pain' and 'interference of working' were significantly more prevalent in non-demented group. However, there are no significant differences between the groups in the 'pain severity', 'prevalence of pain' and 'pain treatment'. Conclusions: Demented group report less pain experience but, still perceived pain. It support previous studies that patient with dementia have increased pain tolerance but preserved pain threshold. Thus, active pain assessment and treatment for patients with dementia is needed.

• Journal of Korean society of Dental Hygiene
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• v.17 no.1
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• pp.155-168
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• 2017

Objectives: The purpose of this research is to examine oral pathogen distribution among elderly with dementia in a care facility to understand the importance of preventively managing oral diseases in terms of preventively managing senile diseases. Methods: From 11th August 2015 to 11th October 2015, gingival crevicular fluid was collected from 130 subjects consisting of demented/non-demented elderly people aged above 65 in care facilities located in the regions of Busan/Gyeonggnam. Based on collected data, real-time PCR analysis on oral pathogen was conducted. Results: The demented elderly group consisting of female patients aged from 0 to 79 indicated higher ratios of T. denticola in comparison to the non-demented elderly group, and the demented elderly group consisting of female patients aged above 80 indicated a high ratio of S. mutans. It was confirmed that P. gingivalis and T. forsythensis categorized under the red complex are correlated, and that bacterial species categorized under the orange complex and bacterial species categorized under the red complex are correlated. Conclusions: Because eldery people with demntia are exposed to periodontal disease and dental caries, their oral environments are more vulnerable. In order to improve such environments, it is necessary to provide care facility personnel with an opportunity to receive education to become aware of the importance of oral health, and it is also necessary to compulsorily assign dental hygienists to care facilities so that they can serve as personnel specializing in oral health management.

• Research in Community and Public Health Nursing
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• v.19 no.2
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• pp.300-309
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• 2008

Purpose: The purpose of this study was to review research trends and show the developmental direction of studies on dementia and nursing interventions for demented elders. Methods: This study analyzed 104 articles on dementia and 23 on nursing interventions for demented elders published until 2007. Results: These dementia studies increased in quantity after 1996, mainly in studies on demented elders and their families and in quantitative studies, Nursing intervention methods were music, light, horticultural therapy, reminiscence and complex therapeutic program, etc. There were experimental studies after 1996, but non-equivalent control group pretest-posttest design was 8(34.8%) of 23(100,0%). The medium sample size was 16.6 for experimental groups, 13 for control groups. The experimental time range was 10-120 minutes a day, frequency was 1-18 a week, and the total frequency was 4-72. The result variables were cognitive function, dementia behavior, emotion, depression, ADL, social behavior, etc. Conclusion: The findings of this review suggest that studies on dementia have been improved in quantity since 1996, but various and effective research methods should be developed as a way to further improve the quality of studies.

• Journal of Home Health Care Nursing
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• v.22 no.2
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• pp.196-205
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• 2015

Purpose: This study investigated evidence for the effects of community-based cognitive rehabilitation programs for demented elderly. Methods: The literature review covered studies between 2004 and 2014, and searched international databases including Ovid-MEDLINE, EMBASE, and the Cochrane Library. The Risk of Bias Assessment Tool for Non-Randomized Studies was used by two reviewers to evaluate independently the quality of the selected articles. Results: Eighteen studies were selected through a systematic search of the literature. About three quarters of the studies showed that the community-based cognitive rehabilitation programs provided by nurses were significantly effective in enhancing cognition among elderly individuals with dementia. Conclusion: Based on these results, we suggest that nurse is an appropriate profession to manage cognitive rehabilitation or cognitive enhancement programs for demented elderly individuals. Therefore, the current system in which caregivers provide cognitive rehabilitation programs for demented elderly individuals must be reformed.

• Journal of Yeungnam Medical Science
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• v.35 no.2
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• pp.205-212
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• 2018

Background: Brain volume is associated with dementia and depression in the elderly. An easy way to predict relative brain volume is to measure head circumference. In this study, we investigated the relationship between head circumference and cognition as well as depression in a non-demented elderly community. Methods: Baseline and follow-up surveys were conducted in 2007 and 2010. At baseline, community residents aged 65 years or over (n=382) within a rural area of South Korea were screened for dementia and symptoms of depression and were followed using the same screening battery after 3 years (n=279). Data from anthropometric measurements (head circumference, height, and body weight), demographics, and blood tests were gathered. Neuropsychological tests, including the Korean version of mini-mental state examination (K-MMSE), clinical dementia rating (CDR) including the CDR-sum of boxes, the Korean version of instrumental activities of daily living, and geriatric depression scale (GDS), were performed. None of the 279 subjects followed were demented. Results: Baseline performance on the K-MMSE and GDS was poorer for participants with smaller head circumferences. Follow-up performance on the MMSE was also poorer for participants with smaller head circumferences. Interestingly, participants with smaller head circumference showed worse GDS scores at baseline but on follow-up examination, participants with larger head circumference showed rapid worsening than those with smaller head circumference with marginal significance by ANOVA test. In regression coefficient analysis, GDS decline showed significant difference. Conclusion: Head circumference was not associated with cognitive change but was associated with symptoms of depression in non-demented community residents.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.4
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• pp.285-292
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• 2008

Purpose : To estimate the prevalence of and identity the associates of cognitive function and depression among people over 70 years of age, and to examine the relationship between cognitive impairment and depression, Methods : The elderly in Pusan area were studied on the Korea version Mini Mental Scale Examination instrument(MMSE-K), Short form of Geriatic Depression Scale(SGDS). Results : The prevalence of cognitive impairment($MMSE{\leq}24$) was 64.4% and that of depression($GDS{\geq}8$) was 40.7% Lower education, no religion and no work experience were associated with cognitive impairment. Depression in demented group was 68.2%, in suspect dementia group was 43.7% and in non-demented group was 9.5%. Conclusion : The prevalence of cognitive impairment and depression in elderly was high and depression was in association with cognitive impairment.

• Journal of Multimedia Information System
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• v.6 no.2
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• pp.75-80
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• 2019

In machine learning, the performance of the system depends upon the nature of input data. The efficiency of the system improves when the behavior of the input data changes from un-normalized to normalized form. This paper experimentally demonstrated the performance of KNN, SVM, LDA and NB on Alzheimer's dataset. The dataset undertaken for the study consisted of 3 classes, i.e. Demented, Converted and Non-Demented. Analysis shows that LDA and NB gave an accuracy of 89.83% and 88.19% respectively in both the cases whereas the accuracy of KNN and SVM improved from 46.87% to 82.80% and 53.40% to 88.75% respectively when input data changed from un-normalized to normalized state. From the above results it was observed that KNN and SVM show significant improvement in classification accuracy on normalized data as compared to un-normalized data, whereas LDA and NB reflect no such change in their performance.

• Korean Journal of Community Nutrition
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• v.29 no.5
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• pp.359-371
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• 2024

Objectives: This study aimed to investigate and compare factors associated with malnutrition according to the presence or absence of dementia in community-dwelling elderly people. Methods: Needs assessment data from 311 long-term care insurance (LTCI) recipients (dementia group 203; non-dementia group 108) that participated in the second pilot program of the integrated care model in community care settings under the Korean LTCI system were used. Descriptive statistical analysis, independent t-test or Fisher's exact test were conducted on the sociodemographic characteristics, health and functional status, and nutritional status of the dementia and non-dementia groups. Logistic regression analysis was conducted to identify factors associated with malnutrition in the dementia and non-dementia groups. Results: Malnutrition occurred in 33.5% and 26.9% of participants in the dementia and non-dementia groups, respectively. In the dementia group, living with family rather than living alone (odds ratio [OR]: 3.81; 95% confidence interval [CI]: 1.50-9.66; P = 0.031), increase in Korean Activities of Daily Living (K-ADL) score (OR: 1.35; 95% CI: 1.17-1.55; P < 0.001), and increase in the Neuropsychiatric Inventory-Questionnaire score (OR: 1.02; 95% CI: 1.01-1.03; P = 0.005) were associated with a higher risk of malnutrition. In the non-dementia group, the risk of malnutrition increased as the K-ADL score increased (OR: 1.20; 95% CI: 1.04-1.39; P = 0.011) and in the depressed group (OR: 2.84; 95% CI: 1.04-7.74; P = 0.042). Conclusion: The study results confirmed the necessity of nutritional management for community-dwelling LTCI recipients. When developing a nutritional management program, considering the differences in factors related to malnutrition between the dementia and non-dementia groups is important. This study proposes policies for improving the LTCI system in terms of nutritional management and the utilization of community resources.