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A Study on the Implementation of Protocol Conformance Test System on LAN and the Conformance Test for CCITT No.7 TCAP (LAN을 이용한 적합성 시험 시스템의 구현과 No.7 TCAP에의 적용에 관한 연구)

  • 윤재일;노승환;조현준;김덕진
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.8
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    • pp.18-25
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    • 1992
  • Given a protocol specification, the task of testing whether an implementation conforms to the specification is called conformance testing. In this paper, the design and implementation of the protocol conformance test system using LAN on heterogeneous systems is descreibed. The test sequence used in this test system is generated using an algorithm on the basis of multiple UIO. The usability of this test system as an application was confirmed by performing the conformance test on the CCITT No.7 TCAP(transaction capabilities application part), implemented by ISDN Laboratory, Korea University in 1990.

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A Compact Divide-and-conquer Algorithm for Delaunay Triangulation with an Array-based Data Structure (배열기반 데이터 구조를 이용한 간략한 divide-and-conquer 삼각화 알고리즘)

  • Yang, Sang-Wook;Choi, Young
    • Korean Journal of Computational Design and Engineering
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    • v.14 no.4
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    • pp.217-224
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    • 2009
  • Most divide-and-conquer implementations for Delaunay triangulation utilize quad-edge or winged-edge data structure since triangles are frequently deleted and created during the merge process. How-ever, the proposed divide-and-conquer algorithm utilizes the array based data structure that is much simpler than the quad-edge data structure and requires less memory allocation. The proposed algorithm has two important features. Firstly, the information of space partitioning is represented as a permutation vector sequence in a vertices array, thus no additional data is required for the space partitioning. The permutation vector represents adaptively divided regions in two dimensions. The two-dimensional partitioning of the space is more efficient than one-dimensional partitioning in the merge process. Secondly, there is no deletion of edge in merge process and thus no bookkeeping of complex intermediate state for topology change is necessary. The algorithm is described in a compact manner with the proposed data structures and operators so that it can be easily implemented with computational efficiency.

Research on the Allergic Potential of Insecticidal CrylAc Proteins of Genetically Modified Rice

  • Son, Dae-Yeul
    • Food Science and Biotechnology
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    • v.15 no.3
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    • pp.385-391
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    • 2006
  • In Korea, different kinds of genetically modified (GM) crops are under development, including GM-rice expressing insecticidal crystal (Cry) proteins of Bacillus thuringiensis (Bt) modified to change a single amino acid. In this study, amino acid (aa) sequences of modified Cry proteins were compared to that of known allergens, and Cry proteins expressed in GM-rice were identified by using Cry protein specific polyclonal antibody. The antigen-antibody reactions were compared between GM and commercial rice to assess the allergic risk of Cry proteins. This analysis showed no known allergen to have more than 35% aa sequence homology with modified Cry proteins in Bt rice over an 80 aa window or to have more than 8 consecutive identical aa. Sera from allergic patients showed some IgE reactivity via immunoblotting and enzyme-linked immunosorbent assay (ELISA), although no differences were seen between GM and commercial rice. Based on these results we conclude that GM rice with modified Cry proteins has no differences in its protein composition or allergenicity relative to commercial rice.

A Study on the Biotelemetry using Infra-red Light (적외선을 이용한 생체신호의 원격측정에 관한 연구)

  • Huh, Soo-Jin
    • Journal of Biomedical Engineering Research
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    • v.14 no.2
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    • pp.169-175
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    • 1993
  • Recently, interest in infra-red(IR) telemetry has increased because of the entirely different propagation and reflection properties of IR light as compared to radiowaves. IR hardly penetrates most materials and is reflected from obstacles. An biotelemetry system using these characteristics of indirect transmitted IR lights was developed, in which 3 ECG's are multiplexed and modulated in PDM/PIM pulse sequence. This proto-type system enables us to realize the non-restraint measurement of biological signals. Compared with conventional radio telemetry, this technique has some merits such as no electromagnetic interference, no frequency allocation problem, no government control over transmission power.

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Management of Persistent Pulmonary Hypertension in Preterm Infants

  • Lee, Byong Sop
    • Neonatal Medicine
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    • v.28 no.1
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    • pp.1-6
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    • 2021
  • Persistent pulmonary hypertension of the newborn (PPHN) is a consequence of the failure of a decrease in the elevated pulmonary vascular resistance after birth. Pulmonary vasodilators, including inhaled nitric oxide (iNO), have been the mainstream of targeted therapy for PPHN, but no drugs have been proven to be effective in preterm infants with PPHN. The fetus remains hemodynamically stable despite lower arterial oxygen tension and pulmonary blood flow as compared to full-term newborns. This adaptation is due to the lower oxygen requirement and high oxygen-carrying capacity of fetal circulation. The immature lungs of preterm infants are more vulnerable to reactive oxygen species, and the response of pulmonary vascular dilatation to blood oxygen tension is blunted in preterm infants. Recently, iNO has been reported to be effective in a selected group of preterm infants, such as those with prolonged preterm rupture of membrane-oligohydramnios-pulmonary hypoplasia sequence. PPHN in preterm infants, along with maximum supportive treatment based on fetal physiology and meticulous assessment of cardiovascular function, is in dire need of new treatment guidelines, including optimal dosing strategies for pulmonary vasodilators.

Genome Sequence Analysis of Chrysanthemum White Rust pathogen Puccinia horiana and Sterol 14-demethylase as Drug Target (국화흰녹병균 Puccinia horiana 유전체 분석과 약물 표적으로서의 sterol 14-demethylase)

  • Kim, Jeong-Gu;Park, Sang Kun;Park, Ha-Seung;Kwon, Soo-Jin;Kim, Seung Hwan;Lee, Dong-Jun;Sohn, Seong-Han;Lee, Byoung Moo;Bae, Shin-Chul;Ahn, Il-Pyung;Kim, Changhoon;Baek, Jeong Hun
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.468-472
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    • 2013
  • Chrysanthemum is an economically important horticultural plant in many countries. The white rust is one of the most devastating diseases caused by an obligate fungal pathogen Puccinia horiana. This is being controlled mostly by application of chemicals. In Korea, 26 items are registered and 10 items contain 6 triazole compounds. To identify and to obtain the information of the drug target for triazoles, possible sterol 14-demethylase orthologues were extracted. From the draft genome information, the nucleotide sequence of the sterol 14-demethylase gene was identified. The amino acid sequence was deduced and the tertiary structure of the enzyme was predicted. This protein showed no less than 84% amino acid sequence identities to those of genus Puccinia and no more than 68% to those of other genus.

Electromyographic Activity, Firing Time and Sequence of the Anterior Temporalis and the Masseter on Chewing Stroke (저작운동시 전측두근과 교근의 근활성 및 활성시기에 관한 연구)

  • Her, Moon-Il;Han, Kyung-Soo
    • Journal of Oral Medicine and Pain
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    • v.24 no.4
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    • pp.421-437
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    • 1999
  • This study was performed to investigate the electromyographic(EMG) activity, firing time and sequence of the mandibular elevator muscle on gum chewing. For this study, 28 patients with temporomandibular disorders(TMD), especially internal derangement of TM joint, and 16 dental students without any signs and symptoms in the masticatory system were selected as the patients group and as the normal group, respectively. The patients group was composed of 14 right and 14 left side affected patients. For recording of EMG activity(${\mu}V$) of the anterior temporalis(TA) and the masseter muscle(MM), and measuring of firing time(millisecond) from the start of mandibular opening movement to the firing of the muscles, BioEMG, BioEGN, and Combo program integrated in the Biopak system(Bioresearch Inc., Milwaukee, USA) were used. Gum chewing stroke was performed in both right and left side for several times, and the first and the second chewing strokes were analysed and compared with regard to EMG activity, firing time, firing sequence, correlation between EMG activity and firing time. The data obtained were analysed by SPSS windows program and the results of this study were as follows : 1. In the patients group, chewing on the affected side showed higher EMG activities in the masseter of the side than those of the contralateral side, but chewing on the unaffected side showed higher EMG activity in the masseter and in the anterior temporalis of the side than those of the contralateral side. 2. There were no difference of firing time between both sides on chewing on the affected side, but firing time in the chewing side were earlier than that of contralateral side on chewing on the unaffected side in patients group. 3. In the normal group, EMG activities in the masseter and in the anterior temporalis in the chewing side were always higher than those of the contralateral side, and there were no difference of firing time between the two sides. 4. In general, firing sequence of four muscles of both sides were ipsilateral TA, ipsilateral MM, contralateral TA, and contralateral MM in earlier order of time in both groups. Correlation coefficients between EMG activity and firing time were negative value, and more significant correlation were appeared in the normal group than in the patients group.

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Identification and sequence analysis of small subunit ribosomal RNA gene of bovine Theileria isolates from Korea and Japan (한국과 일본 소에 감염된 Theileria 분리주의 small subunit ribosomal 유전자의 동정 및 분석)

  • Chae, Joon-seok;Park, Jin-ho;Kwon, Oh-deog;Waghela, Suryakant D.;Holman, Patricia J.;Wagner, Gerald G.;Lee, Joo-mook
    • Korean Journal of Veterinary Research
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    • v.38 no.4
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    • pp.909-917
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    • 1998
  • Six different sequences types(A through E and H) and a subtype(Bl) of the small subunit ribosomal RNA(SSUrRNA) gene were found in bovine Theileria isolates from different areas of Korea and Japan. The sequences were aligned and three hypervariable regions were observed in the nucleotide position ranges 212~231, 261~270 and 632~690. Five of the Theileria isolates yielded sequence type A; these were the field isolates KCB, KCN, and KCJ, and the laboratory stock KLS, all from Korea, and a single isolate from Japan (JHS). This sequence type is identical to the SSUrRNA gene sequence listed for Theileria buffeli (GenBank Accession No. Z15106) from Marula, Kenya. The Korean field isolate KKB yielded only a single sequence type (B), but multiple sequence types were found in some isolates. For example, KCB and JHS isolates yielded both types A and B ; isolate KKW showed types B and H; isolate KCN showed types A, C, and D ; and isolate KCJ showed types A, B, E, and a subtype B1. Finding of the multiple sequences SSUrRNA gene sequences suggests that bovine Theileria isolates from both Korea and Japan may consist of mixed populations.

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Fragment Combination From DNA Sequence Data Using Fuzzy Reasoning Method (퍼지 추론기법을 이용한 DNA 염기 서열의 단편결합)

  • Kim, Kwang-Baek;Park, Hyun-Jung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.10 no.12
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    • pp.2329-2334
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    • 2006
  • In this paper, we proposed a method complementing failure of combining DNA fragments, defect of conventional contig assembly programs. In the proposed method, very long DNA sequence data are made into a prototype of fragment of about 700 bases that can be analyzed by automatic sequence analyzer at one time, and then matching ratio is calculated by comparing a standard prototype with 3 fragmented clones of about 700 bases generated by the PCR method. In this process, the time for calculation of matching ratio is reduced by Compute Agreement algorithm. Two candidates of combined fragments of every prototype are extracted by the degree of overlapping of calculated fragment pairs, and then degree of combination is decided using a fuzzy reasoning method that utilizes the matching ratios of each extracted fragment, and A, C, G, T membership degrees of each DNA sequence, and previous frequencies of each A, C, G, T. In this paper. DNA sequence combination is completed by the iteration of the process to combine decided optimal test fragments until no fragment remains. For the experiments, fragments or about 700 bases were generated from each sequence of 10,000 bases and 100,000 bases extracted from 'PCC6803', complete protein genome. From the experiments by applying random notations on these fragments, we could see that the proposed method was faster than FAP program, and combination failure, defect of conventional contig assembly programs, did not occur.

IDENTIFICATION OF THE AG I/II AND GTFD GENES FROM STREPTOCOCCUS MUTANS GS-5 (연쇄상구균 GS-5의 ag I/II와 gtfD 유전자 클로닝)

  • Jeong, Jin-Woo;Baik, Byeong-Ju;Yang, Yeon-Mi;Seo, Jeong-Ah;Kim, Jae-Gon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.2
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    • pp.357-369
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    • 2005
  • Streptococci are Gram-positive, facultative anaerobes and have no catalase activities. Among mutans streptococci containing ${\alpha}-type$ hemolytic activity, S. mutans is a causative agent for dental caries. As well as acid production yielding the demineralization of tooth enamel, adherence and colonization of S. mutans to the teeth are also important for its virulence. These early colonization are accomplished by the bacterial fibrillar protein, Antigen I/II (Ag I/II) and glucosyltransferase (GTF). Therefore, Ag I/II and GTF are reasonable targets for the development of vaccine against S. mutans GS-5. The ag I/II and gtfD genes from S. mutans GS-5 were cloned and sequenced. Sequence analyses showed the nucleotides sequence of cloned genes had high homology to the sequences previously reported. The sequence alignment of 280 nucleotides between the cloned Ag I/II and the available sequence of the corresponding S. mutans GS-5 showed the perfect match. Comparing with the sequence of gtfD from S. mutans UA159, the corresponding nucleotide sequence of S. mutans GS-5 showed some mismatches and the mismatches introduced changes in four residues out of 105 amino acids, yielding four missense mutations.

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