• 품질경영학회지
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• 제45권4호
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• pp.601-610
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• 2017

Purpose: Authors observe the digital twin enabled smart factory and/or digital manufacturing processes where Industry 4.0 technologies and quality management principles intersect. In this regard, this study reviews existing research regarding digital twins from the perspective of quality management. Methods: Initially, attention was given to how digital twins are manifested in the Industry 4.0 environment. Then, authors identify quality management elements amongst digital twin models, to align the concept of quality with the functional purpose of digital twins. After introducing specific examples of quality management tools applied to digital twins, the authors extend the domain of quality management into the analysis of multimedia format quality data obtained through machine vision. Results: Inspired by cases on the quality management application to digital twins, the authors suggest a framework for Industry 4.0 quality management. The envisioned suggested framework encompasses 4 dimensions, namely, 4M&1E, an application time window, new methodologies, and enabling technologies. Conclusion: Finally, the authors unfold the emerging trend of digital twin enabled smart factories, while emphasizing the necessity of quality management in conjunction with the introduction of digital twins.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 추계학술대회
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• pp.381-383
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• 2015

현대 사회는 노인 인구가 증가하면서 고령화 시대로 진입하였으며, 이른바 65세 이상인 실버세대를 위한 노인의료비, 노인 케어 등의 사회적 비용이 증가하고 있다. 현재 정부나 각종 기업에서 노인 건강을 위해 정보기술을 활용한 다양한 서비스가 제공되고 있음에도 불구하고 여러 가지 한계가 지적되어 활성화가 저해되고 있는 실정이다. 본 연구에서는 사용자의 욕구를 반영한 스마트 헬스 케어 서비스 중에서도 가장 보편화되고 있는 스마트 헬스 밴드의 비즈니스 모델을 개발하고자 한다. 이를 위해, 스마트 헬스 밴드 및 이와 관련한 기술적 기능에 대해 살펴보고, 비즈니스 모델에 대한 구성 요소 및 각 내용에 대해 살펴보고자 한다.

• 한국정밀공학회지
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• 제29권2호
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• pp.229-238
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• 2012

This study is to compare muscle strength between isotonic exercise and isotonic & isokinetic exercise. Participants are 12-man and 10-woman whom they are healthy without medical history in shoulder, elbow and lumbar joint. We performed experiment total 4-weeks that exercise 3-days a week each exercise pattern. We measured shoulder, elbow and lumbar joint torque with BIODEX and circumference of muscle in upper arms once a week. The result showed that isotonic & isokinetic exercise pattern significantly more improved joint torque in shoulder, elbow, lumbar than isotonic exercise pattern. Because that isotonic & isokinetic exercise pattern supplied muscle strengthen and caused muscle contraction. This exercise pattern can be used new exercise training method for major athlete and normal people. Also this pattern can be used rehabilitation treatment.

• 한국IT서비스학회지
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• 제10권1호
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• pp.177-190
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• 2011

Due to the growth of economy and the advancement of IT, the life expectancy has been prolonged and the interests in health have greatly increased. Recently the request for systems that enable measuring the bio-signals of patients in the non medical organizations, such as home, and transmitting them to medical staffs at remote sites for monitoring them. In this paper, we present an agent-based u-health system for patients or suspects with heart diseases. Our system consists of portable devices for measuring bio-signals and agents that perform data collection, data storage, automatic detection of abnormal status in patients, and HL7-based data exchange in a cooperative way. The main features of the system are : the agent-based architecture facilitates the addition of new service modules as well as the modification of existing ones; an intelligent agent is provided which automatically detects situations in which the bio-signals of patients are abnormal; the medical data standard is supported so that the communication with other systems is very easy. To our survey, there have been few previous systems which support all those features in a seamless way.

• 한국의학물리학회지:의학물리
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• 제31권3호
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• pp.81-98
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• 2020

This review aims to provide a brief, comprehensive overview of advanced technologies of nuclear medicine physics, with a focus on recent developments from both hardware and software perspectives. Developments in image acquisition/reconstruction, especially the time-of-flight and point spread function, have potential advantages in the image signal-to-noise ratio and spatial resolution. Modern detector materials and devices (including lutetium oxyorthosilicate, cadmium zinc tellurium, and silicon photomultiplier) as well as modern nuclear medicine imaging systems (including positron emission tomography [PET]/computerized tomography [CT], whole-body PET, PET/magnetic resonance [MR], and digital PET) enable not only high-quality digital image acquisition, but also subsequent image processing, including image reconstruction and post-reconstruction methods. Moreover, theranostics in nuclear medicine extend the usefulness of nuclear medicine physics far more than quantitative image-based diagnosis, playing a key role in personalized/precision medicine by raising the importance of internal radiation dosimetry in nuclear medicine. Now that deep-learning-based image processing can be incorporated in nuclear medicine image acquisition/processing, the aforementioned fields of nuclear medicine physics face the new era of Industry 4.0. Ongoing technological developments in nuclear medicine physics are leading to enhanced image quality and decreased radiation exposure as well as quantitative and personalized healthcare.

• Journal of Platform Technology
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• 제10권1호
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• pp.20-28
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• 2022

인공지능기반의 건강 데이터 검증은 임상 연구에 도움을 줄 뿐만 아니라, 새로운 치료법을 개발하는데 필수 요소가 되었다. 미국 식품의약 관리국이 의학진단 분야 중 인공지능을 이용하여 성인 당뇨병 환자의 경증 이상 당뇨병성 망막증을 감지하는 의료기기 마케팅을 승인한 이래, 인공지능을 이용한 테스트가 증가하고 있다. 본 연구에서는 구글에서 지원하는 Teachable Machine 을 이용하여 이미지 분류 기반의 인공지능모델을 생성하고, 학습을 통한 예측 모델을 완성하였다. 이는 현재 만성질환의 환자들 중 발생하는 안구 질환 중 백내장의 조기 발견하는데 용이하게 할 뿐만 아니라, 눈 건강을 위해 헬스케어 프로그램으로 안 질환 예방을 위한 디지털 개인건강 헬스케어 앱을 개발하기 위한 기초 연구로 진행되었다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.72-72
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• 2020

Various mixtures were prepared depending on the mixing ratio of Scutellaria baicalensis hot water extract (SB-HW) and Chrysanthemum morifolium ethanol extract (CM-E) and their anti-inflammatory activity were compared. Among them, SB-HW (80 ㎍/mL)/CM-E (120 ㎍/mL) or SB-HW (40 ㎍/mL)/CM-E (160 ㎍/mL) significantly inhibited LPS-stimulated NO and IL-6 levels in RAW 264.7 cells. The SB-HW (80 ㎍/mL)/CM-E (120 ㎍/mL) mixture, which was determined as active mixture, significantly reduced MUC5AC secretion in PMA and LPS-induced NCI-H292 cells. The active mixture also reduced the production of PGE2 and IL-8 in PMA-induced A549 cells. LC-MS/MS analysis showed that the active mixture was composed of high contents of flavone glycosides, such as baicalin and cynaroside. Western blot analysis indicated that the active mixture suppressed phosphorylation of ERK, JNK, and p38, associating with the inhibition of MAPK signaling. Taken together, our results suggest that the active mixture could be applied as a new anti-inflammatory herbal medicine

• 대한방사선기술학회지:방사선기술과학
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• 제47권2호
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• pp.97-105
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• 2024

The examination needle used in ultrasound biopsy is a medical device used to determine whether there is an abnormality in the tissue. Typically, stainless steel is the standard material used for such needles; however, this study wanted to identify a material that could better enhance sound compared to traditional stainless steel. In this study, six types of needle materials available with the biopsy gun were inserted into pork and ultrasound images according to the curved probe and linear probe were evaluated using ultrasound equipment. The findings revealed significant improvements in ultrasound acoustic enhancement with alternative materials compared to stainless steel (p<0.05). The results regarding the depth of each ultrasound image using the curved probe showed that tungsten and brass had high sound enhancement(p<0.05), while with the linear probe, sound enhancement was high in brass, pla, aluminum, and copper(p<0.05). Due to these results, the previously used stainless needle showed lower ultrasound acoustic enhancement than the five types of materials being compared. Consequently, the outcomes of this study provide valuable insights for the development of new needle technologies aimed at minimizing patient risks and improving diagnostic accuracy.

• 보건행정학회지
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• 제25권4호
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• pp.253-255
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• 2015

The concept of precision medicine-prevention and treatment strategies that take individual variability into account-is hot issue of US in the year 2015. Precision medicine is a new concept that approach patients individually by there characteristics, such as genome, life style, environmental exposure, etc. For developing the precision medicine, National Institute of Health of US has been prepared the Precision Medicine Initiative Cohort Program, at least 1 million people cohort. The US President Obama announced the Precision Medicine Initiative on 30th January 2015. He announced that he will pioneer a new model of patient-powered research that promises to accelerate biomedical discoveries and provide clinicians with new tools, knowledge, and therapies to select which treatments will work best for which patients. Most medical treatments have been designed for the 'average patient.' As a result of this 'one-size-fits-all-approach,' treatments can be very successful for some patients but not for others. This is changing with the emergence of precision medicine, an innovative approach to disease prevention and treatment that takes into account individual differences in people's genes, environments, and lifestyles. Precision medicine gives clinicians tools to better understand the complex mechanisms underlying a patient's health, disease, or condition, and to better predict which treatments will be most effective. The healthcare researcher should prepare the new medicine era such as bio-information technology convergence, big data study.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.87-87
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• 2013

The interface between nanomaterials and biosystems is emerging as one of the broadest and most dynamic areas of science and technology, bringing together biology, chemistry, physics and many areas of engineering, biomedicine. The combination of these diverse areas of research promised to yield revolutionary advances in healthcare, medicine, and life science. For example, the creation of new and powerful nanosensors that enable direct, sensitive, and rapid analysis of biological and chemical species can advance the diagnosis and treatment of disease, discovery and screening of new drug molecules. Nanowire based sensors are emerging as a powerful and general platform for ultrasensitive and multiplex detection of biological and chemical species. Here, we present the studies about noble metal nanowire sensors that can be used for sensitive detection of a wide-range of biological and chemical species including nucleic acids, proteins, and toxic metal ions. Moreover, the optical and electrochemical applications of noble metal nanowires are introduced. Noble metal nanowires are successfully used as plasmonic antennas and nanoelectrodes, thereby provide a pathway for a single molecule sensor, in vivo neural recording, and molecular injection and detection in a single living cell.