• Title/Summary/Keyword: New constituents

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Studies on the Analysis of Constituents of Deer Horn(I) -Assay of Trace Elements and TLC Pattern Analysis of Gangliosides- (산지별 녹용(鹿茸)류의 성분분석 연구(I) -미량금속의 정량 및 Gangliosides의 TLC Pattern 분석-)

  • Hong, Nam-Doo;Won, Do-Hee;Kim, Nam-Jae;Chang, Seung-Youb;Youn, Whang-Geum;Kim, Hae-Soo
    • Korean Journal of Pharmacognosy
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    • v.22 no.3
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    • pp.171-182
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    • 1991
  • Several experiments were carried for the purpose of establishing the basis for the quality evaluation of deer horn. Deer horn originated from China, New Zealand, Soviet and Alaska were used as objectives and some constituents involved in deer horn were assayed and compared with one another. Five kinds of trace elements including Ca and Fe were determined by atomic absorbance spectroscopy. The more the region came down from the top of the deer horn, the more the ratio of Ca to Fe content (Ca/Fe) was increased. The same increasing tendancy was observed in the case of ash content. Gangliosides were isolated from deer horn by alumina column chromatography and identified by TLC using gangliosides Type II obtained from bovine brain as the standard material. The TLC chromatograms were scanned by dual wavelength TLC scanner, then those TLC profiles were compared. Deer horn from China and New Zealand were analogous but those from Soviet and Alaska were each distinguished in their TLC profiles.

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Studies on Chemical Constituents of Three Marine Sponges, Siphonochalina siphonella in Egypt and Arenosclera sp. and Gelliodes sp. in Vietnam

  • 기대원
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.16-44
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    • 2020
  • Cancer is the second leading cause of death in the world. According to the 2018 reports, one in six people worldwide is reported to die as a result of cancer. The discovery of anticancer drugs has been utilized extensively, but there has been no report on excellent selective activity in cancer cells. The discovery of bioactive substances from marine sponges has been the limelight in the pharmaceutical field over the past decade owing to the production of many bioactive compounds from the sponges to protect themselves against the environment. On top of that, marine sponges also produced cytotoxic compounds such as terpenoids, alkaloids, steroids, and peptides which suggests that marine sponges have high potential in the development of anticancer drugs. Thus, this study aimed to obtain new cytotoxic compounds from S. siphonella in Egypt and Arenoscelra sp. and Gelliodes sp. in Vietnam, and further investigation of the extract from these marine sponges led to isolation of ten new compounds and 21 known compounds. Chapter 1 will discuss about the isolation and structure elucidation of eight new polyacetylene derivatives from S. siphonella and their cytotoxic activities. The isolation and structural elucidation of one new polybrominated iododiphenyl ether from Arenosoclea sp. as well as cytotoxic activities of the isolated compounds will be reported in chapter 2. Finally, isolation and structure elucidation of new compounds from the marine sponge Gelliodes sp. and their cytotoxic activities will be discussed in chapter 3.

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Fomitoside K, a New Lanostane Triterpene Glycoside from the Fruiting Body of $Fomitopsis$ $nigra$

  • Lee, In-Kyoung;Jung, Jin-Young;Yeom, Ji-Hee;Ki, Dae-Won;Lee, Myeong-Seok;Yeo, Woon-Hyung;Yun, Bong-Sik
    • Mycobiology
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    • v.40 no.1
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    • pp.76-78
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    • 2012
  • In an effort to identify the chemical constituents of fruiting bodies of $Fomitopsis$ $nigra$, a new lanostane triterpene glycoside, designated as fomitoside K, has been isolated from its methanolic extract. Its chemical structure was assigned on the basis of various spectroscopic studies.

Bending analysis of FGM plates using a sinusoidal shear deformation theory

  • Hadji, Lazreg;Zouatnia, Nafissa;Kassoul, Amar
    • Wind and Structures
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    • v.23 no.6
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    • pp.543-558
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    • 2016
  • The response of functionally graded ceramic-metal plates is investigated using theoretical formulation, Navier's solutions, and a new displacement based on the high-order shear deformation theory are presented for static analysis of functionally graded plates. The theory accounts for a quadratic variation of the transverse shear strains across the thickness, and satisfies the zero traction boundary conditions on the top and bottom surfaces of the plate without using shear correction factors. The plates are assumed to have isotropic, two-constituent material distribution through the thickness, and the modulus of elasticity of the plate is assumed to vary according to a power-law distribution in terms of the volume fractions of the constituents. Numerical results of the new refined plate theory are presented to show the effect of the material distribution on the deflections, stresses and fundamental frequencies. It can be concluded that the proposed theory is accurate and simple in solving the static and free vibration behavior of functionally graded plates.

Study on the Alkaloids from Thalictrum fauriei

  • Chen, Chung-Hsiung
    • Korean Journal of Pharmacognosy
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    • v.17 no.1
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    • pp.49-54
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    • 1986
  • To explore the biological activities of Thalictrum alkaloids, a study was initiated to investigate the alkaloidal constituents from T. fauriei, a species indigenous to Taiwan. Extensive fractionation of the ethanolic extract provided three known aporphines, (+)-oconovine (Ia), (+)-isocorydine (Ib), and (+)-corydine (Ic) from nonphenolic tertiary base fraction. From quaternary base fraction two new protoberberinium salts, thalifaurine (IIa), dehydrodiscretine (IIb), in addition to magnoflorine (III), were isolated. The structure of both new compounds were confirmed by total syntheses. Fractionation of phenolic bases yielded a dihydromorphinandienone, (-)-ocobotrine (IV), as well as a novel aporphine-pavine dimer, tentatively named EP-10. The structure of EP-10 was established by means of 2D NMR studies. Preliminary study indicated a weak activity of lyzing Hela cells, in vitro, for EP-10.

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A Study on the Cultural Meanings of Underclothes Advertisements in Women's Magazines (여성잡지에 나타난 속옷광고의 문화적 의미 연구)

  • 김미영;한명숙
    • The Research Journal of the Costume Culture
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    • v.9 no.5
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    • pp.783-797
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    • 2001
  • This study examines the cultural meanings of underclothes advertisements through the analysis of advertisement messages appeared in women's magazines of Korea which are , and published between 1965 and 1999 mainly targeting the women at the age of 20s through 40s. The method of study is mainly qualitative with subsidiary citations from the results of content analysis. The advertisement messages identified in underclothes advertisements are 1) body care, 2) gender role, 3) commercialization of eroticism, 4) feminism, 5) men's social status and masculinity, 6) social issues of concern and ideologies of the time. Advertisements produce a new meaning through a dynamic mixture of the advertisement's visual and verbal factors. Such a new meaning then can become a part of culture and therefore we can obtain insights of a society culture by analyzing the advertisement messages of underclothes advertisements. Advertisements bring definite changes to the culture through long-term and implicit influences on the constituents of the culture.

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NEW TNF-$\alpha$ RELEASING INHIBITORS AS CANCER PREVENTIVE AGENTS FROM TRADITIONAL HERBAL MEDICINE, AND HNRNP B1, A NEW EFFECTIVE BIOMARKER FOR CHEMOPREVENTION OF HUMAN LUNG CANCER

  • Fujiki, Hirota;Suganuma, Masami;Okabe, Sachiko;Fujimoto, Nobukazu;Yoshida, Takashi;Sueoka, Naoko;Sueoka, Eisaburo
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.22-23
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    • 2001
  • Based on the success of green tea as a cancer preventive, herbal medicines are now also attracting attention as potential sources of cancer preventive agents. Using inhibition of TNF-$\alpha$ release assay, we studied Acer nikoense (Megusurino-ki in Japanese): Inhibitory potential was found in the leaf extract, and the main active constituents were identified as geraniin and corilagin. The $IC_{50}$/ values for TNF-$\alpha$ release inhibition were 43 $\mu$M for geraniin and 76 $\mu$M for corilagin, whereas that for (-)-epigallocatechin gallate (EGCG)was 26 $\mu$M.(omitted)

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Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage

  • Jung, Joohee;Choi, Jae Sue;Jeong, Choon-Sik
    • Toxicological Research
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    • v.30 no.1
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    • pp.45-48
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    • 2014
  • Helicobacter pylori (H. pylori) is the most important factor of gastric disease in clinical practice. Moreover, smoking, stress and a poor diet may be additive factors for gastric damage. With these factors, increasing infection of H. pylori triggers gastritis, gastric ulcers and gastric cancer. To develop a new protective agent, we are concerned with plant-derived extract. The extract of Coptis chinensis (C. chinensis) and its constituents were investigated to assess their protective activities against gastric damage. The C. chinensis extract showed a scavenging effect against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radicals, inhibition of H. pylori colonization and antiulcerogenic activities in rat. In particular, palmatine derived from C. chinensis was found to be the novel protective agent. It is better than the C. chinensis extract, berberine, a well-known constituent of C. chinensis. We suggest that palmatine from the root cortex of C. chinensis may be a good candidate for the development of new pharmaceuticals to prevent gastric disease.

Nomenclature of Pyroxenes

  • Morimoto, N.;Fabries, J.;Ferguson, A.K.;Ginzburg, I.V.;Ross, M.;Seifert, F.A.;Zussman, J.;Aoki, A.;Gottardi, G.
    • Journal of the Mineralogical Society of Korea
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    • v.1 no.2
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    • pp.131-145
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    • 1988
  • This is the final report on the nomenclature of pyroxenes by the Subcommittee on Pyroxenes established by the Commission on New Minerals and Mineral Names of the International Mineralogical Association. The recommendations of the Subcommittee as put forward in this report have been formally accepted by the Commission. Accepted and widely used names have been chemically defined, by combining new and conventional methods, to agree as far as possible with the consensus of present use. Twenty names are formally accepted, among which thirteen are used to represent the end members of definite chemical compositions. In common binary solid-solution series, species names are given to the two end members by the "50% rule." Adjectival modifiers for pyroxene mineral names are defined to indicate unusual amounts of chemical constituents. This report includes a list of 105 previously used pyroxene names that have been formally discarded by the Commission.

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New Evaluation and Test of Sidewall's Rotational Stiffness of Radial Tire

  • Kim Young-Woo;Kim Yong-Sung
    • Journal of Mechanical Science and Technology
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    • v.20 no.6
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    • pp.748-758
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    • 2006
  • In this paper, we have revisited the estimation of the rotational stiffness of sidewall of radial tire and have suggested a new method for evaluation of the rotational stiffness. Since thicknesses, and volume fractions of the constituents of sidewall are varied depending on radial position, the equivalent shear modulus of the sidewall also depends on radial position. For the estimation of rotational stiffness of sidewall's rubber, we have divided its cross-section into sufficient numbers of small parts and have calculated the equivalent shear modulus of each part of sidewall. Using the shear moduli of divided parts, we have obtained the rotational stiffness by employing in-plane shear deformation theory. This method is expected to be a useful tool in tire design since it relates such basic variables to the global stillness of tire. Applying the calculation method to a radial tire of P205/60R15, we have compared its rotational stiffness with experimental one.