• Advances in Traditional Medicine
• /
• v.6 no.1
• /
• pp.27-33
• /
• 2006

The Sasang constitutional medicine classifies the mankind into four constitutional types according to the individual psychological and physical traits. Differences in the Sasang constitutional medicine may be explained by the genetic factors. In order to determine the association of Sasang constitutional classification and interleukin-1 receptor antagonist (IL-1Ra) in genetic susceptibility to ischemic stroke, we classified the four constitutional types in ischemic stroke patients (n = 125) and the healthy control subjects (n = 107), and genotyped for IL-1Ra polymorphism by polymerase chain reaction (PCR) methods. The distribution of the $IL1RN^*1/IL1RN^*2$ genotype in the ischemic stroke patients was significantly different from the healthy controls (OR = 6.09; P =0.0134). And the prevalence of $IL1RN^*1/IL1RN^*2$ genotype was increased in Taeum-in ischemic stroke patients, as compared to Taeum-in healthy controls (OR = 14.71; P = 0.0144). These results suggest that $IL1RN^*1/IL1RN^*2$ genotype in Taeum-in might be associated with the increasing risk for ischemic stroke. Furthermore, this relationship could provide the basis for a new approach in the investigation of the etiology of ischemic stroke.

• Journal of Platform Technology
• /
• v.8 no.3
• /
• pp.22-29
• /
• 2020

The 4th industrial revolution is progressing by country as a mega trend that leads various technological convergence directions in the social and economic fields from the initial simple manufacturing innovation. The epidemic of infectious diseases such as COVID-19 is shifting digital-centered non-face-to-face business from economic operation, and the use of AI and big data technology for personalized services is essential to spread online. In this paper, we analyze cases focusing on the application of artificial intelligence technology, which is a key technology for the effective implementation of the digital new deal promoted by the government, as well as the major technological characteristics of the 4th industrial revolution and describe the use cases in the field of disaster response. As a disaster response use case, AI assistants suggest appropriate countermeasures according to the status of the reporter in an emergency call. To this end, AI assistants provide speech recognition data-based analysis and disaster classification of converted text for adaptive response.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.27 no.5
• /
• pp.677-682
• /
• 2013

Impaired glucose tolerance(IGT) & Impaired fasting glucose(IFG) were standardized in 1979 by the National Diabetes Data Group and the World Health Organization as a risk factor for type 2 diabetes. The main clinical significance of IGT & IFG shows some risk factors on type 2 diabetes, cardiovascular disease and component of the metabolic syndrome. In 1997, the American Diabetes Association(ADA) proposed the new classification and diagnostic criteria for diabetes, which wss striction on the diagnostic baseline of Diabetes from 140 mg/dl to 126 mg/dl. This is because that the early diagnosis and treatments can prevent chronic complications. In the oriental medicine, Gamiyookmigihwang-tang has been using for the treatments of Diabetes including IGT & IFG; however, there have not been enough studies about the effect of the glycemic control objectively. So clinical studies have been performed on a mild DM(Diabetes Mellitus) patient with IGT and IFG in order to investigate whether there is hypoglycemic effect of Gamiyookmigihwang-tang. Prior to the study, for two weeks fasting blood sugar(FBS) and postprandial 2hrs(PP2hrs) glucose were checked. in addition ECG, T-cholesterol, TG, HbA1c levels were measured; then, Gamiyookmigihwang-tang has administrated for 4 weeks. and FBS, PP2hrs, T-cholesterol, TG, HbA1c were measured again after the herb medicine treatment. FBS, PP2hrs glucose levels and other measuring levels (T-cholesterol, TG, HbA1c) were decreased by the administration of Gamiyookmigihwang-tang. Gamiyookmigihwang-tang has hypoglycemic effects on a mild DM patient with IGT and IFG.

• The Korean Journal of Applied Statistics
• /
• v.21 no.4
• /
• pp.571-580
• /
• 2008

The logistic regression analysis is widely used in the area of customer relationship management and credit risk management. It is well known that the maximum likelihood estimation is not appropriate when multicollinearity exists among the regressors. Thus we propose the logistic principal components regression to deal with the multicollinearity problem. In particular, new method is suggested to select proper principal components. The selection method is based on the condition index instead of the eigenvalue. When a condition index is larger than the upper limit of cutoff value, principal component corresponding to the index is removed from the estimation. And hypothesis test is sequentially employed to eliminate the principal component when a condition index is between the upper limit and the lower limit. The limits are obtained by a linear model which is constructed on the basis of the conjoint analysis. The proposed method is evaluated by means of the variance of the estimates and the correct classification rate. The results indicate that the proposed method is superior to the existing method in terms of efficiency and goodness of fit.

• Journal of Chest Surgery
• /
• v.55 no.2
• /
• pp.151-157
• /
• 2022

Background: We investigated surgical outcomes after the surgical repair of cor triatriatum sinister (CTS). Methods: Thirty-two consecutive patients who underwent surgical repair of CTS from 1993 through 2020 were included in this study. The morphological characteristics, clinical features, and surgical outcomes were described and analyzed. Results: The median age and body weight at operation were 9 months (interquartile range [IQR], 3-238 months) and 7.5 kg (IQR, 5.8-49.6 kg), respectively. There were 16 males (50%). According to the modified Lucas classification, type IA (classical CTS) was most common (n=20, 62.5%). Atrial septal defect was associated in 22 patients (68.8%) and anomalous pulmonary venous return in 8 patients (25%). Pulmonary hypertension was preoperatively suspected with a high probability in 18 patients (56.3%). There was 1 early death (3.1%) after emergent membrane excision and hybrid palliation in a high-risk hypoplastic left heart syndrome patient. There were no late deaths. The overall survival rate was 96.9% at 15 years post-repair. No early survivors required reoperation during follow-up. Most survivors (31 of 32 patients, 96.9%) were in New York Heart Association functional class I at a median follow-up of 74 months (IQR, 39-195 months). At the latest echocardiography performed at a median of 42 months (IQR, 6-112 months) after repair, no residual lesion was observed except in 1 patient who had moderate pulmonary hypertension (mean pulmonary arterial pressure of 36 mm Hg). Conclusion: Surgical repair of cor triatriatum could be performed safely and effectively with an extremely low risk of recurrence.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.37 no.3
• /
• pp.75-81
• /
• 2014

To establish a new creative economy, the worldwide efforts have been made to wriggle out the old economic paradigm after the financial crisis of 2008. When it comes to the limitation of the viability. the start up companies have a high risk of failure. Therefore business incubator (BI) should carry out the role to improve their viability. As for the maximization of the effect on the business incubating services as move in companies, it is important for BI to increase the level of business incubating services by the systemic and scientific measurement. This study showed that the quality of the BI center services was measured by Kano analysis and the previous research as follows. First, BI quality attribute by Timko's customer satisfaction came out into the attractive qualities on the 14 items that amount to the 70% of 20 business incubating services items. It is desirable to perform the strategy for the satisfaction. Secondly, basic business incubating services were interpreted as the one-dimensional quality like incubating spaces, parking facilities, security facilities, industry technology development funds, and incubating managers. Finally, training and educational service was recognized as indifferent quality. Futhermore, the improvement and the limitation of this study as well as the interpretation of analysis results are also provided.

• Journal of Environmental Health Sciences
• /
• v.43 no.2
• /
• pp.111-121
• /
• 2017

Objectives: In this study, an analysis was performed on local government adaptation plans for climate change focusing on the health sector. The limitations of past study results have been summarized and new research subjects for preparing for the advanced second period (2018-2022) of the local government adaptation plan for climate change have been suggested. Methods: First, a review of the literature related to vulnerability assessment and adaptation plans was performed. Next, a comparison among the 16 metropolitan governments' vulnerability assessment results and adaptation plans was made. Lastly, a classification of the adaptation policy and budgets to compare with their real budget amounts was performed. Results: The results show that there is a categorizing discrepancy between vulnerability assessment and adaptation policy. In addition, their adaptation budget amounts turned out to be too large in comparison with the actual budget amounts. Conclusion: The first period (2013-2017) local government adaptation plans for climate change had some limitations. This is because there was a rapid driving force for establishing adaptation plans under the green growth strategy in Korea. Now, we are confronting a risk of adaptation to climate change. By expanding this approach, the government would be able to set up a detailed policy to improve the plans during the second period.

• Journal of the Korea Safety Management & Science
• /
• v.19 no.2
• /
• pp.31-39
• /
• 2017

Classify of explosion hazardous areas must be made at the site where flammable materials are used. This reason is that it is necessary to manage ignition sources in of explosion hazardous areas in order to reduce the risk of explosion. If such an explosion hazard area is widened, it becomes difficult to increase the number of ignition sources to be managed. The method using the virtual volume currently used is much wider than the result using CFD(Computational Fluid Dynamics). Therefore, we tried to improve the current method to compare with the new method using leakage characteristics. The result is a realistic explosion hazard if the light gas is calibrated to the mass and the heavy gas is calibrated to the lower explosion limit. However, it is considered that the safety factors should be taken into account in the calculated correction formula because such a problem should be considered as a buffer for safety.

• Structural Monitoring and Maintenance
• /
• v.10 no.3
• /
• pp.243-260
• /
• 2023

Indonesia has had seismic codes for earthquake-resistant structures designs since 1970 and has been updated five times to the latest in 2019. In updating the Indonesian seismic codes, seismic hazard maps for design also update, and there are changes to the Peak Ground Acceleration (PGA). Indonesian seismic design uses the concept of building performance levels consisting of Immediate occupancy (IO), Life Safety (LS), and Collapse Prevention (CP). Related to this performance level, cases still found that buildings were damaged more than their performance targets after the earthquake. Based on the above issues, this study aims to analyze the performance of base isolation design on existing target buildings and analyze the seismic fragility for a case study in Indonesia. The target building is a prototype design 8-story medium-rise residential building using the reinforced concrete moment frame structure. Seismic fragility analysis uses Incremental Dynamic Analysis (IDA) with Nonlinear Time History Analysis (NLTHA) and eleven selected ground motions based on soil classification, magnitude, fault distance, and earthquake source mechanism. The comparison result of IDA shows a trend of significant performance improvement, with the same performance level target and risk category, the base isolation structure can be used at 1.46-3.20 times higher PGA than the fixed base structure. Then the fragility analysis results show that the fixed base structure has a safety margin of 30% and a base isolation structure of 62.5% from the PGA design. This result is useful for assessing existing buildings or considering a new building's performance.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.17 no.11
• /
• pp.2987-3002
• /
• 2023

In 2015, the number of senior citizens aged 65 and over in Korea was 6,662,400, accounting for 13.1% of the total population. Along with these social phenomena, risk information related to the elderly is increasing every year. In particular, a fall accident caused by a fall can cause serious injury to an elderly person, so special attention is required. Therefore, in this paper, we implemented a system that monitors fall accidents and informs them in real time to minimize damage caused by falls. To this end, beacon-based indoor location positioning was performed and biometric information based on an integrated module was collected using various sensors. In other words, a multi-functional sensor integration module was designed based on Arduino to collect and monitor user's temperature, heart rate, and motion data in real time. Finally, through the analysis and prediction of measurement signals from the integrated module, damage from fall accidents can be reduced and rapid emergency treatment is possible. Through this, it is possible to reduce the damage caused by a fall accident, and rapid emergency treatment will be possible. In addition, it is expected to lead a new paradigm of safety systems through expansion and application to socially vulnerable groups.