• Title/Summary/Keyword: Network Expansion

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IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance

  • Dong Hyun Kim;Won-Woo Lee
    • IMMUNE NETWORK
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    • v.24 no.3
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    • pp.21.1-21.16
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    • 2024
  • IL-1, a pleiotropic cytokine with profound effects on various cell types, particularly immune cells, plays a pivotal role in immune responses. The proinflammatory nature of IL-1 necessitates stringent control mechanisms of IL-1-mediated signaling at multiple levels, encompassing transcriptional and translational regulation, precursor processing, as well as the involvement of a receptor accessory protein, a decoy receptor, and a receptor antagonist. In T-cell immunity, IL-1 signaling is crucial during both the priming and effector phases of immune reactions. The fine-tuning of IL-1 signaling hinges upon two distinct receptor types; the functional IL-1 receptor (IL-1R) 1 and the decoy IL-1R2, accompanied by ancillary molecules such as the IL-1R accessory protein (IL-1R3) and IL-1R antagonist. IL-1R1 signaling by IL-1β is critical for the differentiation, expansion, and survival of Th17 cells, essential for defense against extracellular bacteria or fungi, yet implicated in autoimmune disease pathogenesis. Recent investigations emphasize the physiological importance of IL-1R2 expression, particularly in its capacity to modulate IL-1-dependent responses within Tregs. The precise regulation of IL-1R signaling is indispensable for orchestrating appropriate immune responses, as unchecked IL-1 signaling has been implicated in inflammatory disorders, including Th17-mediated autoimmunity. This review provides a thorough exploration of the IL-1R signaling complex and its pivotal roles in immune regulation. Additionally, it highlights recent advancements elucidating the mechanisms governing the expression of IL-1R1 and IL-1R2, underscoring their contributions to fine-tuning IL-1 signaling. Finally, the review briefly touches upon therapeutic strategies targeting IL-1R signaling, with potential clinical applications.

Climate change messages in the fashion industry discussed at COP28

  • Yeong-Hyeon Choi;Sangyung Lee
    • The Research Journal of the Costume Culture
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    • v.32 no.4
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    • pp.517-546
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    • 2024
  • The aim of this study is to investigate the fashion industry's response to climate change and how these discussions unfolded at the 28th Conference of the Parties (COP28) to the United Nations Framework Convention on Climate Change (UNFCCC). Climate change response projects by B Corp-certified fashion companies are examined, focusing on stakeholder efforts and reviewing online media reports. Text data were collected from web documents, interviews, and op-eds relating to COP28 from December 2018 to April 2024 and analyzed using text mining and semantic network analysis to identify critical keywords and contexts. The analysis revealed that the fashion industry is fulfilling its environmental responsibilities through various strategies, prompting changes in consumer behavior by advocating sustainable consumption, including carbon removal, energy transition, and recycling promotion. Stakeholders in online media and those present at COP28 discussed issues relating to climate change in the fashion industry, focusing on environmental protection, energy, greenhouse gas emissions, sustainable material usage, and social responsibility. Key issues at COP28 included policy and regulation, climate change response, energy transition, carbon emissions management, and environmental, social, and governance (ESG) standards. Additionally, by examining the main collections exhibited at the fashion show during COP28, the study analyzed how messages about climate change were conveyed. Fashion companies communicated the industry's response through exhibitions and fashion shows, suggesting a move toward balancing environmental protection and economic growth through the development of sustainable materials, the expansion of recycling and reuse practices, and the modern reinterpretation of cultural heritage.

Collaborative Governance and Development of the Yeongnam Region : a Conceptual Reconsideration (협력적 거버넌스와 영남권 지역 발전: 개념적 재고찰)

  • Choi, Byung-Doo
    • Journal of the Korean association of regional geographers
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    • v.21 no.3
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    • pp.427-449
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    • 2015
  • Network governance can be defined as collaborative process to develop a new socio-political order through civil society centered networking with government and market, and the term 'collaborative governance' can be used in a sense that the basis of governance is collaborative process. In particular, it can be stressed that collaborative governance between regions need double collaborative processes, that is, collaboration between local governments and collaboration between local government and local civil society within a region. Yet, the collaboration as a core element of collaborative governance should not be seen as a pure normativity presupposing confidence and reciprocity, but as a strategy based on competition and antagonism. The normativity implied in the concept of collaborative governance may not realized in actual process, and tends to be mobilized as a rationale for justifying neoliberal strategies. In order to overcome such limits of collaborative governance, the concept of collaborative governance should be reconstructed. This paper suggests that collaborative governance can be seen as hegemonic governing process in a Gramcian sense operating in the government plus civil society, and that, radicalizing Ostrom's concept, it also can be seen as a governing process producing polycentricity by self-regulating subjects. Finally, collaborative governance between regions needs expansion of material basis for economic complementarity and construction of infrastructure as well as a discursive process in order to enhance connectivity between them.

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LTE Spectrum Policy: Focused on the OECD 12 Countries (이동통신 LTE 주파수 정책: 주요국 사례를 중심으로)

  • Jun, Soo-Yeon;Jeong, In-Jun
    • Journal of Digital Convergence
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    • v.12 no.8
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    • pp.1-18
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    • 2014
  • Recently, many of the mobile network operators or telcos are introducing the LTE service in order to effectively cope with an explosive increasing mobile traffics due to an expansion of the use of smart phones. The 1.8GHz, 2.6GHz, and 800MHz band classes are most widely used for LTE. In particular, the 1.8GHz band class is the most useful one in terms of the reusability of the existing (2G) network, global harmonization, bandwidth, eco-system of equipments and devices, and so on. In recent years, major countries in the world have allocated the 1.8GHz band spectrum in a wide bandwidth unit suitable for the upcoming LTE-Advanced service. This paper surveyed the 1.8GHz band spectrum allocation policies of the 12 OECD countries, including Republic of Korea. From the survey, we have found that they rebuilt or refarmed the existing holders' bands, recovered the public (i.e., military)-use bands, and allocated the bands in a wide bandwidth and in an equal or similar size.

A Study on Authentication Management and Communication Method using AKI Based Verification System in Smart Home Environment (스마트 홈 환경에서 AKI기반 검증 시스템을 활용한 인증관리 및 통신 기법에 관한 연구)

  • Jin, Byung Wook;Park, Jung Oh;Jun, Moon Seog
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.16 no.6
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    • pp.25-31
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    • 2016
  • With the development of IOT technology and the expansion of ICT services recently, a variety of home network services have been advanced based on wired and wireless high speed telecommunication. Domestic and global companies have been studying on the innovative technology for the users using IOT based technology and the environment for the smart home services has been gradually developed. The users live their lives with more convenience due to the expansions and developments of smart phones. However, the threatening on the security of the smart home network had occurred by various attacks with the connection to the smart environment telecommunication, lack of applications on low powered and light weight telecommunication, and the problems of security guideline. In addition, the solutions are required for the new and variant attacking cases such as data forgery and alteration of the device for disguising approach with ill will. In this article, the safe communication protocol was designed using certification management technique based on AKI which supplemented the weakness of PKI, the existing certification system in the smart environment. Utilizing the signature technique based on ECDSA, the efficiency on the communication performance was improved, and the security and the safety were analyzed on the security threat under the smart home environment.

Efficient Schemes for Scaling Ring Bandwidth in Ring-based Multiprocessor System (링 구조 다중프로세서 시스템에서 링 대역폭 확장을 위한 효율적인 방안)

  • Jang, Byoung-Soon;Chung, Sung-Woo;Jhang, Seong-Tae;Jhon, Chu-Shik
    • Journal of KIISE:Computer Systems and Theory
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    • v.27 no.2
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    • pp.177-187
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    • 2000
  • In the past several years, many systems which adopted ring topology with high-speed unidirectional point-to-point links have emerged to overcome the limit of bus for interconnection network of clustered multiprocessor system. However, rapid increase of processor speed and performance improvement of local bus and memory system limit scalability of system with point-to-point link of standard bandwidth. Therefore, necessity to extend bandwidth is emphasized. In this paper, we adopt PANDA system as base model, which is clustering-based multiprocessor system. By simulating a model adopting commercial processor and local bus specification, we show that point-to-point link is bottleneck of system performance, and bandwidth expansion by more than 200% is needed. To expand bandwidth of interconnection network, it needs excessive design cost and time to develop new point-to-point link with doubled bandwidth. As an alternative to double bandwidth, we propose several ways to implement dual ring -simple dual ring, transaction-separated dual ring, direction-separated dual ring- by using off-the-shelf point-to-point links with IEEE standard bandwidth. We analyze pros. and cons. of each model compared with doubled-bandwidth single ring by simulation.

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A Study of Production Technology of Digital Contents upon the Platform Integration : Focusing on Cross - Platform Game (플랫폼 통합에 따른 디지털콘텐츠 제작기술 경향연구 : 크로스 플랫폼게임(Cross-Platform Game) 사례를 중심으로)

  • Han, Chang-Wan
    • Cartoon and Animation Studies
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    • s.14
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    • pp.151-164
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    • 2008
  • Cross platform game has brought about the expansion of game market, which results in technology innovation overcoming the limit of game consumption. The new model integrates both off and online game services. Gamers can now enjoy game service regardless of age, time, and space. If the technology evolution model of digital contents like cross-platform game engine can provide contents for several platform at the same time, the interactive service can be utilized into maximum level. It is also necessary to allocate, switch data as well as to innovate the transmission technology of data according to each platform. Providing the same contents for several platform as many as possible can be the most suitable strategy to enhance the efficiency and profits. However if the interactive service can be accomplished completely, the development of data switching technology and distribution should be made. To be a leader in the next digital contents market, one should develop the network engine technology which can embody the optimization of consumption in the interactive network service.

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A Study on the Utilization and Problems of Online Dispute Resolution : Focusing on the Online Arbitration (온라인분쟁해결의 활용과 문제점에 관한 연구 - 온라인중재를 중심으로 -)

  • Yu, Byoung-Yook
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.19
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    • pp.191-223
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    • 2003
  • Electronic commerce and the Internet offer unprecedented opportunities. The explosive expansion of the use of the Internet makes it possible for businesses to expand their markets and render services. Global transaction costs are easy to cut off using Internet and transaction speed is faster than before. Where cyberspace is not free from claims, Offline transaction can lead to problems and disputes the same is for cyberspace transactions. However ADR is not meet for the online transaction for speed, cost and open network system, ODR methods to resolve electronic commerce conflicts is crucial for building confidence and permitting access to justice in an online business environment. The use of the Internet and the network in dispute resolution has an impact on the types of communication implied in the relevant processes such as automated negotiation, online mediation and online arbitration and involves new technological issues such as the integrity and confidentiality of data and communication used to transmit and store data. Among the ODR systems Online Arbitration is currently binding both parties disputed and can achieve the aim of dispute award the same as the traditional arbitration. Arbitration is based on the New York Convention 1958, Arbitration Model law 1985 and national Arbitration Act that are founded on territorial area and rested on arbitration agreement, constitution of the arbitral tribunal, due process, final and binding award and enforcement of the arbitration award. To compare with this issues Online arbitration has unnecessarily legal unstability and risk. ODR is the burgeoning field and has created a new issues. All such issues which have been debated in the ADR are composed with ODR. But these are not limited Some of issues are further complicated by the nature of the online environment such as confidentiality and principle of parties. It is true that online arbitration should comply with legal provisions, but which is impossible to adhere of the law. Flexible translation and functional equivalence of legal provisions are needed for acceptance of electronic commerce disputes. Finally electronic commerce now takes place on the Internet, it is inevitable that the commercial world wants access to dispute resolution process that best suits the new commercial environment. ODR methods are processing for development and legal issues are considered by both national and international authorities. Introduction of new Conventions or amend Convention and Model law of ODR comes near.

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Optimum Configuration of Single Frequency Network DMB to enhance the QoS and Service coverage (QoS 개선과 서비스 커버리지 확장을 위한 단일 주파수망 지상파 DMB 최적화 배치)

  • Cho, Young-Hun;Won, Chung-Ho;Seo, Jong-Soo
    • Journal of Broadcast Engineering
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    • v.19 no.4
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    • pp.439-452
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    • 2014
  • This paper suggests the method to extend service area by using the transmit offset delay in T-DMB single frequency network (SFN). In general, synchronization of the transmit time of all site can be done by using the reference clock of GPS, which dose not reflect the details geographical characteristics and transmit specifications of each site. Applying the site-specific transmit offset delay, we could extend the service area of SFN T-DMB. Applying the transmit offset delay, it is found that the signal quality in the region of weak receive field strength was improved and upto 4~8 km service area expansion was achieved by satisfying the minimum field strength ($45dB{\mu}V/m$) recommended by the Korea Communications Commission (KCC). Site-specific offset delay was calculated considering the geographic service area characteristics, distribution of electric field strength between neighboring sites and site-specific service target area. Experiments were carried out in order to analyze impact of calculated offset delay on the T-DMB SFN and also to confirm that the offset delay extends T-DMB service coverage. The experiment was done in metropolitan T-DMB service areas.

A Study on the Development of Dynamic Models under Inter Port Competition (항만의 경쟁상황을 고려한 동적모형 개발에 관한 연구)

  • 여기태;이철영
    • Journal of the Korean Institute of Navigation
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    • v.23 no.1
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    • pp.75-84
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    • 1999
  • Although many studies on modelling of port competitive situation have been conducted, both theoretical frame and methodology are still very weak. In this study, therefore, a new algorithm called ESD (Extensional System Dynamics) for the evaluation of port competition was presented, and applied to simulate port systems in northeast asia. The detailed objectives of this paper are to develop Unit fort Model by using SD(System Dynamics) method; to develop Competitive Port Model by ESD method; to perform sensitivity analysis by altering parameters, and to propose port development strategies. For these the algorithm for the evaluation of part's competition was developed in two steps. Firstly, SD method was adopted to develop the Unit Port models, and secondly HFP(Hierarchical Fuzzy Process) method was introduced to expand previous SD method. The proposed models were then developed and applied to the five ports - Pusan, Kobe, Yokohama, Kaoshiung, Keelung - with real data on each ports, and several findings were derived. Firstly, the extraction of factors for Unit Port was accomplished by consultation of experts such as research worker, professor, research fellows related to harbor, and expert group, and finally, five factor groups - location, facility, service, cargo volumes, and port charge - were obtained. Secondly, system's structure consisting of feedback loop was found easily by location of representative and detailed factors on keyword network of STGB map. Using these keyword network, feedback loop was found. Thirdly, for the target year of 2003, the simulation for Pusan port revealed that liner's number would be increased from 829 ships to 1,450 ships and container cargo volumes increased from 4.56 million TEU to 7.74 million TEU. It also revealed that because of increased liners and container cargo volumes, length of berth should be expanded from 2,162m to 4,729m. This berth expansion was resulted in the decrease of congested ship's number from 97 to 11. It was also found that port's charge had a fluctuation. Results of simulation for Kobe, Yokohama, Kaoshiung, Keelung in northeast asia were also acquired. Finally, the inter port competition models developed by ESB method were used to simulate container cargo volumes for Pusan port. The results revealed that under competitive situation container cargo volume was smaller than non-competitive situation, which means Pusan port is lack of competitive power to other ports. Developed models in this study were then applied to estimate change of container cargo volumes in competitive relation by altering several parameters. And, the results were found to be very helpful for port mangers who are in charge of planning of port development.

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