• Advances in Traditional Medicine
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• v.4 no.1
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• pp.53-59
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• 2004

The effect of aqueous and alcoholic extract of the leaves of Ocimum. sanctum was studied on the spontaneous movements of the whole worm (w.w) preparation and nerve muscle (n.m.) complex of Setaria cervi (S. cervi) and on the survival of microfilariae (m.f.) in vitro. Both the extracts caused inhibition of the spontaneous motility of the w.w. and n.m. complex of S. cervi characterized by initial stimulation followed by reversible paralysis, aqueous extract at a higher concentration showed immediate effect and irreversible paralysis. The concentration required to inhibit the movements of n.m. complex was $1/4^{th}$ for aqueous and $1/3^{rd}$ for alcoholic extract compared to that for the w.w., suggesting a cuticular permeability barrier. On the m.f. the lethal concentration (LC 50 and LC 90) were 35 and 50 ng/ml for aqueous whereas, 60 and 85 ng/ml for alcoholic extracts respectively.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.2 no.1
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• pp.59-70
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• 2004

The purpose of this study were to determine the changes between pre, during, intermed, post of each two groups of 16 persons and to compare the effect of transcutaneous electrical nerve stimulation(TENS) at shenmen of auricular point on experimental pressure pain and tactile threshold measured at both ulnar styloid process and medial malleoli. Sixteen healthy adult men and women, aged 20 to 28 years, were assigned randomly to eight of one groups. Control group received TENS to exception of auricular point. Experimental group received TENS to shenmen of auricular point. Experimental pressure pain and tactile pain threshold at the both ulnar styloid process and medial malleoli was determined with algometer and von frey filament before 10 minute, during 10 minute, intermediate and post 30 min of treatment. In pressure pain and tactile threshold showed a statistically significant increase(p<0.05) ipsilateral and contralateral of treatment group. These results suggest that TENS at shenmen of auricular point has the capability to higher pressure pain and tactile threshold in whole body.

• International Journal of Oral Biology
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• v.32 no.4
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• pp.153-160
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• 2007

The superficial dorsal horn, particularly substantia gelatinosa (SG) in the spinal cord, receives inputs from small-diameter primary afferents that predominantly convey noxious sensation. Reactive oxygen species (ROS) are toxic agents that may be involved in various neurodegenerative diseases. Recent studies indicate that ROS are also involved in persistent pain through a spinal mechanism. In the present study, whole cell patch clamp recordings were carried out on SG neurons in spinal cord slice of young rats to investigate the effects of hydrogen peroxide on neuronal excitability and excitatory synaptic transmission. In current clamp condition, tert-buthyl hydroperoxide (t-BuOOH), an ROS donor, depolarized membrane potential of SG neurons and increased the neuronal firing frequencies evoked by depolarizing current pulses. When slices were pretreated with phenyl-N-tert-buthylnitrone (PBN) or ascorbate, ROS scavengers, t-BuOOH did not induce hyperexcitability. In voltage clamp condition, t-BuOOH increased the frequency and amplitude of spontaneous excitatory postsynaptic currents (sEPSCs), and monosynaptically evoked excitatory postsynaptic currents (eEPSCs) by electrical stimulation of the ipsilateral dorsal root. These data suggest that ROS generated by peripheral nerve injury can modulate the excitability of the SG neurons via pre- and postsynaptic actions.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.21 no.2
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• pp.215-219
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• 1999

This article discusses the diagnosis, anatomic consideration, and surgical management of masseter muscle hypertrophy. Surgical correction is advised for patients who have esthetic complaints. Esthetic improvement can be achieved by surgery and not by conservative treatment. Recently, the intraoral method, which leaves no scar on the face and minimizes the possibility of injury to the marginal branch of the facial nerve, has been supported by many surgeons. Patients who complained of marked swelling of unilateral or bilateral mandibular angle area and showed abnormal bony growth at the mandibular angle area and enlarged masseter muscle received mandibular angle shaving and excision of the inner layer of masseter muscle with intraoral approach. After operation, physiotherapy was done with EAST(eletrical acupuncture stimulation therapy) for encouraging the mouth opening and reducing the swelling. They showed early maximum mouth opening and reduction of swelling.

• Physical Therapy Korea
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• v.9 no.4
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• pp.69-76
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• 2002

본 연구에서는 상부 승모근의 근막통증(myofascial pain syndrome; MPS)를 대상으로 이완상태에서 근 활성도를 측정해보고, 통증을 감소시키는 데 주로 이용되는 경피신경자극 치료 후 근 활성도에 어떠한 영향을 미치는지 알아보기 위해 실시하였다. 본 연구의 대상자는 근막 통증으로 진단을 받은 총 10명을 대상으로 실시하였다. 주관적 시각 척도(visual analogue scale; VAS)와 압통 역치 측정계(pressure threshold meter)를 이용하여 경피신경자극 전, 후 통증의 정도를 평가하였고, 표면 근전도를 이용하여 이완시 근 활성도를 측정하였다. 치료 기구는 경피신경자극기(TENS: HAT-2000)를 이용하였다. 치료 전과 비교하여 VAS는 통증이 심한 쪽과 약한 쪽 모두에서 유의하게 감소하였으며(p<.05), 압통 역치는 통증이 심한 쪽과 약한 쪽 모두에서 유의한 차이가 없었고(p>.05), 근 활성도는 통증이 심한 쪽에서 유의하게 감소하였다(p<.05).

• Annals of Clinical Neurophysiology
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• v.7 no.2
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• pp.88-92
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• 2005

Blink reflex could be a useful tool to differentiate facial synkinesis as one of complications of facial neuropathy, from volitional associated movements. We had performed applied blink reflex test for 23 patients with objective evidence of hemifacial weakness in which orbicularis oculi muscle(zygomatic branch) and mentalis muscle(mandibular branch) are electrophysiologically evaluated in response to supraorbital stimulation of trigeminal nerve. For an unaffected side of face there is no evidence of positive blink reflex from the mentalis muscle. We concluded that a positive blink reflex from mentalis muscle is almost always suggestive of chronic facial neuropathy even in clinical silence of facial synkinesis, or an aberrant reinnervation after peripheral facial neuropathy, and does not electrophysiologically correlate with the severity of facial palsy.

• The Korean Journal of Pain
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• v.26 no.2
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• pp.177-180
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• 2013

Trigeminal neuralgia (TN) is characterized by recurrent paroxysms of unilateral facial pain that typically is severe, lancinating, and activated with cutaneous stimulation. There are two types of TN, classical TN and atypical TN. The pain nature of classical TN are the same as those described above, whereas atypical TN is characterized by constant, burning pain. We describe the case of a 49-year-old male presenting with right-sided facial pain. The patient was diagnosed with temporomandibular joint disorder at a dental clinic and was on medical treatment, but his symptoms worsened gradually. He was referred to our pain clinic for further evaluation. Radiologic evaluation, including MRI, showed a parapharyngeal tumor. For the relief of TN, a right mandibular nerve (V3) root block was performed at our pain clinic, and then he was scheduled for radiation and chemotherapy.

• The Journal of Internal Korean Medicine
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• v.37 no.2
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• pp.243-250
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• 2016

Objective: We report a case of a 73-year-old Korean male with vertigo and nausea, both of which were brought about by head repositioning. The condition was diagnosed as benign paroxysmal positional vertigo (BPPV).Method: The patient was treated with acupuncture, electroacupuncture, cupping, transcutaneous electrical nerve stimulation (TENS), and herbal medicine (Bosimsahwacheonggan-tang [補心瀉火淸肝湯]). We conducted the vertigo symptoms scale (VSS) and the dizziness handicap inventory (DHI) to evaluate the degree of the patient’s symptoms.Results: Vertigo and nausea started to improve after the administration of Bosimsahwacheonggan-tang, but although the patient took the anti-vertigo medication and a tranquilizer after the symptoms became aggravated, no prominent improvements could be observed.Conclusion: These results suggest that traditional Korean medical treatment may be effective in treating peripheral vertigo due to BPPV.

• Journal of Oriental Neuropsychiatry
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• v.22 no.3
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• pp.1-11
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• 2011

Objectives : As the number of patient with dementia increases, interest in mild cognitive impairment (MCI), which is a pre-dementia stage, has been expanding. In this study, we investigated the effects from selected clinical research articles to evaluate the effectiveness of non-pharmacological interventions. Methods : We searched MCI related articles on MEDLINE and the Web of Science using keywords related to MCI. We selected 26 articles, and 13 evaluated efficiency using the Jadad score. Results : Physical exercise and cognitive remediation techniques were effective for improving MCI. Transcutaneous electrical nerve stimulation, taichi, and music belonged to "perhaps" effectiveness group. Many of the 13 articles that evaluated MCI using the Jadad score evaluated them as "good" or "poor", and only three articles evaluated MCI as "excellent". Conclusions : The present evidence suggests that cognitive remediation techniques to improve memory and physical exercise were effective for people with MCI. However, further studies are needed to identify the physical exercise effects.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.1
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• pp.1-5
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• 2019

Purpose: In chronic stroke patients, muscle tone and stiffness increase due to ankle spasticity. Electrotherapy may control the spasticity of patients with central nerve system damage via neurophysiological mechanisms. Therefore, this study was conducted to determine the immediate effects of interferential current therapy on gastrocnemius (GCM) muscle. Methods: This study was a one-group pretest-posttest design and 20 stroke patients participated. The experimental group underwent interferential current therapy for GCM for 30 minutes. Muscle tone (MT) and stiffness were assessed using MYOTONE(R) PRO. After 30 minutes of interferential current therapy, MT and stiffness of the affected side and unaffected side by GCM were measured. Results: After interferential current therapy, the medial GCM MT (Hz) was significantly reduced in stroke patients. There was a significant difference in MT between affected GCM muscles and unaffected side medial GCM muscles before intervention, but there was no significant difference after interferential current therapy. Conclusion: This study demonstrated that interferential current therapy had a positive effect, producing an immediate decrease in the medial GCM muscles tone of stroke patients. However, this study employed a one-group pretest-posttest design. Future studies will show differences in muscle tone compared to a control group or other electrical stimulation treatments.