• Journal of Korean Neurosurgical Society
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• 제55권3호
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• pp.148-151
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• 2014

Objective : Posture-induced radial neuropathy, known as Saturday night palsy, occurs because of compression of the radial nerve. The clinical symptoms of radial neuropathy are similar to stroke or a herniated cervical disk, which makes it difficult to diagnose and sometimes leads to inappropriate evaluations. The purpose of our study was to establish the clinical characteristics and diagnostic assessment of compressive radial neuropathy. Methods : Retrospectively, we reviewed neurophysiologic studies on 25 patients diagnosed with radial nerve palsy, who experienced wrist drop after maintaining a certain posture for an extended period. The neurologic presentations, clinical prognosis, and electrophysiology of the patients were obtained from medical records. Results : Subjects were 19 males and 6 females. The median age at diagnosis was 46 years. The right arm was affected in 13 patients and the left arm in 12 patients. The condition was induced by sleeping with the arms hanging over the armrest of a chair because of drunkenness, sleeping while bending the arm under the pillow, during drinking, and unknown. The most common clinical presentation was a wrist drop and paresthesia on the dorsum of the 1st to 3rd fingers. Improvement began after a mean of 2.4 weeks. Electrophysiologic evaluation was performed after 2 weeks that revealed delayed nerve conduction velocity in all patients. Conclusion : Wrist drop is an entrapment syndrome that has a good prognosis within several weeks. Awareness of its clinical characteristics and diagnostic assessment methods may help clinicians make diagnosis of radial neuropathy and exclude irrelevant evaluations.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권4호
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• pp.679-700
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• 1996

Inferior alveolar nerve dysfunction may be the result of trauma, disease, or iatrogenic injury. Inferior alveolar nerve injury is inherent risk in endodontic therapy, orthognathic surgery of the mandible, and extraction of mandibular teeth, particularly the third molars. The sensory disturbances of inferior alveolar nerve associated with such injury have been well documented clinical problem that is commonly evaluated by several clinical sensory test including Tinels sign, Von Frey test(static light touch detection), directional discrimination, two-point discrimination, pin pressure nociceptive discrimination, and thermal test. These methods used to detect and assess inferior alveolar nerve injury have been subjective in nature, relying on the cooperation of the patients. In addition, many of these techniques are sensitive to differences in the examiners experience and skill with the particular technique. Data obtained at different times or by different examiners are therefore difficult to compare. Prior experimental studies have used electro diagnostic methods(sensory evoked potential) to objectively evaluate inferior alveolar nerve after nerve injury. This study was designed with inferior alveolar nerve of rabbit. Several types of injury including mind, moderate, severe compression and perforation with 19 gauze, 21 gauze needle and 6mm, 10mm traction were applied for taking the sesory evoked ppterntial. Latency and amplitude of injury rabbit inferior alveolar nerve were investigated with sensory evoked potential using unpaired t-test. The results were as follows : 1. Intensity of threshold (T1) was $128{\pm}16{\mu}A$ : latency, $0.87{\pm}0.07$ microsecond : amplitude, $0.4{\pm}0.1{\mu}V$ : conduction velocity, 23.3 m/s in sensory evoked potential of uninjured rabbit inferior alveolar nerve. 2. Rabbit inferior alveolar nerve consists of type II and III sensory nerve fiber. 3. Latency was increased and amplitude was decreased in compression injury. The more injured, the more changed in latency and amplitude. 4. Findings in perforation injury was similar to compression injury. Waveform for sensory evoked potential improved by increasing postinjured time. 5. Increasing latency was prominent in traction injury rabbit inferior alveolar nerve. 6. In microscopic histopathological findings, significant degeneration and disorganization of the internal architecture were seen in nerve facicle of severe compression and 10mm traction group. From the above findings, electrophysiological assessment(sensory evoked potential) of rabbit injured inferior alveolar nerve is reliable technique in diagnosis and prognosis of nerve injury.

• PNF and Movement
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• 제19권1호
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• pp.97-104
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• 2021

Purpose: The human body can experience a variety of injuries. As a result, it may be difficult to directly treat the damaged area. In such a case, indirect treatment is required. Indirect treatment is typically PNF treatment. Morphological changes in muscle have been confirmed through several previous studies; however, few studies have analyzed neurological changes. Therefore, the purpose of this study was to determine how irradiation during resistance exercise using a diagonal pattern effects neurological excitability. Methods: Electromyography was performed on 13 healthy adults. A compound muscle action potential (CMAP) was obtained through a median motor nerve conduction velocity test, which was conducted before and after performing the irradiation exercise and general exercise. Results: Compared to baseline measurements, there was no significant difference in the latency of the irradiation exercise and general exercise. The amplitude of the CMAP measured after the irradiation exercise was significantly higher than after general exercise. Conclusion: Neurological excitability was high in irradiation during resistance exercise using a diagonal pattern. When clinically direct treatment is difficult, it is thought that irradiation can be used indirectly as a technique to induce nerve excitability.

• 대한물리치료과학회지
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• 제3권1호
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• pp.929-941
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• 1996

본 연구는 1994년 1월 24일부터 동년 4월 8일까지 부산 메리놀병원 내과 및 신경과에서 당뇨병으로 진단되어 당뇨교실에서 치료를 받고 있는 입원 및 외래환자 67명(남 37명, 여 30명 :평균연령 $52.55{\pm}13.67$세)과 병력 및 이학적 소견상 말초신경에 이상이 없다고 진단된 직원 및 그 가족 53명(남 28명, 여 25명 : 평균연령 $45.75{\pm}12.21$세)을 대상으로 본 병원 신경생리검사실에서 가중침자감각역치와 감각신경전도검사를 측정한 결과는 다음과 같다. 1. 가중침자감각역치는 양측 손과 발의 측정한 모든 부위에서 당뇨병 환자 중 증상군, 무증상군 그리고 대조군 간에 있어서 통계학적으로 유의한 차이를 나타냈는데, 대조군이 당뇨병 환자군보다 낮았고 당뇨병 환자중 무증상군이 증상군보다 낮게 나타났다. 2. 당뇨병 환자에 있어서 가중침자감각역치는 증상군과 무증상군 모두 연령과 당뇨병유병기간과는 통계학적으로 유의한 상관관계를 나타내어 연령이 많고 유병기간이 길수록 가중침자감각역치는 높았으며 기타 체중, 신장 및 교육수준과는 유의한 상관성이 없었다. 3. 대조군에 있어서 가중침자감각역치는 연령과는 통계학적으로 유의한 상관관계를 나타냈고 교육수준과는 역상관관계를 나타내어 연령이 많고 교육수준이 낮을 수록 가중침자감각역치는 높았으며 체중과 신장과는 유의한 상관성이 없었다. 4. 가중침자감각역치에 있어서 연령을 보정하고 각 부위별로 세 군 간의 상관관계를 살펴본 결과 우측 제 5수지와 좌측 발에서의 가중침자감각역치는 증상군과 무증상군, 증상군과 대조군 및 무증상군과 대조군 간에 모두 통계학적으로 유의한 차이를 나타냈으나(p<0.05), 그 외 양측 제 2수지와 좌측 제 5수지 그리고 우측 발에서의 가중침자감각역치는 증상군과 대조군, 그리고 무증상군과 대조군 간에서만 통계학적으로 유의한 차이를 나타냈고 증상군과 무증상군 간에는 유의한 차이가 나타나지 않았다(p<0.05). 5. 각 부위별 가중침자감각역치와 감각신경의 전도속도 및 활동전위 진폭과의 상관관계는 세 군 모두다 측정한 모든 부위에서 통계학적으로 유의한 상관관계를 나타냈다. 이상의 결과로 보아 감각신경 전도검사가 가중침자감각역치보다 정확한 검사이긴 하지만 가중침자감각역치는 당뇨크리닉의 외래에서 말초감각장애 정도를 신속히 알고 싶을 때나, 감각신경 전도검사가 불가능한 상황에서 표피감각을 측정하는데 매우 유용한 검사방법이라 생각된다.

• Annals of Clinical Neurophysiology
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• 제2권1호
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• pp.21-26
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• 2000

저자들은 정상 대조군과 CTS 환자군을 대상으로 막대전극을 이용하여 M P P D N의 감각신경전도검사를 실시하여 다음과 같은 결과를 얻었다. 1. MPPDN의 감각신경전도속도의 정상범위는 $38.7{\pm}4.2$(D1), $32.0{\pm}4.6$(D2), $34.2{\pm}4.4$(D3) m/sec로서 서로 유의한 차이가 있었다. 2. MPPDN의 감각신경전도속도의 정상범위는 좌우에서 서로 유의한 차이가 없었다. 3. CTS 환자에서 측정한 MPPDN의 감각신경전도속도는 각각 $35.3{\pm}8.9$(D1), $20.2{\pm}5.2$(D2), $20.2{\pm}5.1$(D3) m/sec로서 대조군에서 얻은 정상범위와 유의한 차이가 있었다.

• Annals of Clinical Neurophysiology
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• 제19권1호
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• pp.54-57
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• 2017

Distal acquired demyelinating symmetric (DADS) neuropathy is a variant form of chronic inflammatory demyelinating polyradiculoneuropathy. A 54-year-old man presented with gait disturbance owing to weakness in both legs. Nerve conduction studies showed demyelinating sensorimotor polyneuropathy, and laboratory studies demonstrated anti-GM1 and anti-GD1b IgG antibodies, but no anti-myelin associated glycoprotein activity. We suggest that an antiganglioside antibodies assay needs to be applied when DADS neuropathy is suspected in order to improve the classification of dysimmune neuropathies.

• Clinical and Experimental Pediatrics
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• 제53권4호
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• pp.607-611
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• 2010

Bickerstaff 뇌간 뇌염은(BBE) 4주 이내의 진행성이며, 비교적 대칭성으로 오는 안근 마비와 실조증, 의식 장애 또는 심부건 반사 항진 등의 임상적 특징을 가지며, 뇌간을 침범하는 타 질환을 배제하였을 때 진단할 수 있는 드문 질환이다. 혈청 또는 뇌척수액의 항 Ganglioside 항체(GM, GD and GQ) 는 때로 BBE의 진단에 도움이 되기도 하며, 뇌 자기 공명 영상, 뇌 척수액 검사, 신경 전도 검사 및 근 전도 검사 등은 진단에 크게 도움이 되지 않는다. 저자들은 안근 마비, 실조증, 언어 운동 장애, 연하 장애, 점진적 사지 마비, 의식 저하 등의 증상을 보이며 혈청과 뇌척수액에서 anti-GM1 항체의 증가를 보여 BBE로 진단하고 면역 글로불린과 스테로이드 치료 후 완치되었던 9세의 여아의 증례를 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다.

• Journal of Korean Neurosurgical Society
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• 제42권5호
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• pp.382-387
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• 2007

Objective : Cubital tunnel syndrome is the second most common entrapment neuropathy of the upper extremity. Although many different operative techniques have been introduced, none of them have been proven superior to others. Simple cubital tunnel decompression has numerous advantages, including simplicity and safety. We present our experience of treating cubital tunnel syndrome with simple decompression in 15 patients. Methods : According to Dellon's criteria, one patient was classified as grade 1, eight as grade 2, and six as grade 3. Preoperative electrodiagnostic studies were performed in all patients and 7 of them were rechecked postoperatively. Five patients of 15 underwent simple decompression using a small skin incision (2 cm or less). Results : Preoperative mean value of motor conduction velocity (MCV) within the segment (above the elbow-below the elbow) was $41.8{\pm}15.2\;m/s$ and this result showed a decrease compared to the result of MCV in the below the elbow-wrist segment ($57.8{\pm}6.9\;m/s$) with statistical significance (p<0.05). Postoperative mean values of MCV were improved in 6 of 7 patients from $39.8{\pm}12.1\;m/s$ to $47.8{\pm}12.1\;m/s$ (p<0.05). After an average follow-up of $4.8{\pm}5.3$ months, 14 patients of 15 (93%) reported good or excellent clinical outcomes according to a modified Bishop scoring system. Five patients who had been treated using a small skin incision achieved good or excellent outcomes. There were no complications, recurrences, or subluxation of the ulnar nerve. Conclusion : Simple decompression of the ulnar nerve is an effective and successful minimally invasive technique for patients with cubital tunnel syndrome.

• Journal of Preventive Medicine and Public Health
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• 제28권4호
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• pp.899-910
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• 1995

1994년 1월 24일부터 동년 4월 8일까지 부산 메리놀병원 내과 및 신경과에서 당뇨병으로 진단되어 당뇨교실에서 치료를 받고 있는 입원 및 외래환자 67명(남37명, 여 30명 : 평균연령 $52.55{\pm}13.67$세)라 병력 및 이학적 소견상 말초신경에 이상이 없다고 진단된 직원 및 그 가족 53명(남 28명, 여 25명 : 평균연령 $45.75{\pm}12.21$세)을 대상으로 본 병원 신경생리검사실에서 가중침자감각역치와 감각신경전도검사를 측정한 결과는 다음과 같다. 1. 가중침자감각역치는 양측 손과 발의 측정한 모든 부위에서 당뇨병 환자 중 증상군, 무증상군 그리고 대조군간에 있어서 통계학적으로 유의한 차이를 나타냈는데, 대조군이 당뇨병 환자군보다 낮았고 당뇨병 환자 중 무증상군이 증상군보다 낮게 나타났다. 2. 당뇨병 환자에 있어서 가중침자감각역치는 증상군과 무증상군 모두 연령과 당뇨병유병기간과는 통계학적으로 유의한 상관관계를 나타내어 연령이 많고 유병기간이 길수록 가중침자감각역치는 높았으며 기타 체중, 신장 및 교육수준과는 유의한 상관성이 없었다. 3. 대조군에 있어서 가중침자감각역치는 연령과는 통계학적으로 유의한 상관관계를 나타냈고 교육수준과는 역상관관계를 나타내어 연령이 많고 교육수준이 낮을수록 가중침자감각역치는 높았으며 체중과 신장과는 유의한 상관성이 없었다. 4. 가중침자감각역치에 있어서 연령을 보정한 후의 각 부위별 세 군간의 차이는 우측 제5수지와 좌측 발에서는 세 군 서로 모두 통계학적으로 유의한 차이를 나타냈으나(p<0.05), 양측 제2수지와 좌측 제5수지 그리고 우측 발에서의 가중침자감각역치는 증상군과 대조군, 그리고 무증상군과 대조군간에서만 통계학적으로 유의한 차이를 나타내었다(p<0.05). 5. 각 부위별 가중침자감각역치와 감각신경의 전도 속도 및 활동전위 진폭과의 상관관계는 측정한 모든 부위에서 통계학적으로 유의한 상관관계를 나타냈다(p<0.05). 이상의 결과로 보아 감각신경 전도검사가 가중침자감각역치보다 정확한 검사이긴 하지만 가중침자감각역치는 말초감각장애 정도를 외래에서 신속히 알고 싶을 때나, 감각신경 전도검사가 불가능한 상황에서 매우 유용한 검사방법이라 생각된다.

• 대한암한의학회지
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• 제21권2호
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• pp.51-61
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• 2016

Background : Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect in cancer patients who were exposed to chemotherapy. CIPN impacts on the quality of life and could delay chemotherapy. The aim of this review was to assess the therapeutic effectiveness of herbal medicine in CIPN patients. Methods : Randomized controlled trials (RCTs) were included in this review. We searched MEDLINE, Cochrane database, EMBASE, CNKI, Wanfang and four Korean databases without restrictions on time or language. The risk of bias was assessed using the Cochrane risk of bias tool. Results : Eleven RCTs involving 706 patients met the inclusion criteria. Eleven different herbal medicines were examined in the included trials. Almost RCTs showed insufficiency in the reporting randomization method and allocation concealment. One trial used allocation concealment and a double-blinding method. Five studies reported that participants dropped out of RCTs and conducted an 'as-treated analysis'. One trials reported adverse effects of herbal medicine. In ten of the eleven trials, the use of herbal medicine had shown significant differences in clinical symptoms or nerve conduction velocity. Conclusions : The use of herbal medicines for CIPN showed significant improvements in the management of CIPN. However, conclusions cannot be drawn because of the generally low quality of methodology and low quantity of data for each single herbal medicine. Further rigorous trials are needed.