• Title/Summary/Keyword: Negative therapy

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Serum 8 Hydroxydeoxyguanosine and Cytotoxin Associated Gene A as Markers for Helicobacter pylori Infection

  • Yeniova, Abdullah Ozgur;Uzman, Metin;Kefeli, Ayse;Basyigit, Sebahat;Ata, Naim;Dal, Kursat;Guresci, Servet;Nazligul, Yasar
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5199-5203
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    • 2015
  • Background: Helicobacter pylori (H.pylori) is associated with chronic gastritis, peptic ulcers, gastric adenocarcinomas and mucosa associated tissue lymphomas. Cytotoxin associated gene A (CagA) is one of the virulence factors of H.pylori. It is hypothesized that reactive oxygen species (ROS) play roles in H.pylori associated disease especially in development of gastric adenocarcinoma. Individuals infected with H.pylori bearing CagA produce more ROS than others. 8-hydroxydeoxyguanosine (8OHdG) is an in vitro marker of DNA damage and oxidative stress. The aim of this study was to investigate the relationship between 8OHdG level, H.pylori infection and CagA and alterations of serum 8OHdG level after H.pylori eradication. Materials and Methods: Patients admitted with dyspeptic complaints and upper gastrointestinal endoscopy were assessed. H.pylori was determined from histopathology of specimens. Serum 8OHdG levels of three groups (H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive) were compared. Patients with H.pylori infection received eradication therapy. Serum 8OHdG levels pretreatment and posttreatment were also compared. Results: In total, 129 patients (M/F, 57/72) were enrolled in the study. Serum 8OHdG level of H.pylori negative, H. pylori positive CagA negative and H.pylori positive CagA positive groups were significantly different ($5.77{\pm}1.35ng/ml$, $5.43{\pm}1.14ng/ml$ and $7.57{\pm}1.25ng/ml$ respectively, p=0.05). Furthermore, eradication therapy reduced serum 8OHdG level ($6.10{\pm}1.54ng/ml$ vs $5.55{\pm}1.23ng/ml$, p=0.05). Conclusions: Individuals infected with H.pylori bearing CagA strains have the highest serum 8OHdG level and eradication therapy decreases the serum 8OHdG level. To the best of our knowledge this is the first study that evaluated the effect of CagA virulence factor on serum 8OHdG level and the effect of eradication therapy on serum 8OHdG levels together. Eradication of CagA bearing H.pylori may prevent gastric adenocarcinoma by decreasing ROS. 8OHdG level may thus be a good marker for prevention from gastric adenocarcinoma.

Qualitative Approach to Maintaining the Effect of Fashion Therapy (패션테라피 효과 유지에 대한 질적 접근)

  • Lee, Sae Eun;Lee, Yuri
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.3
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    • pp.311-326
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    • 2019
  • Previous studies on the effect of fashion therapy have been conducted with psychiatric patients; however, this study explores the effects in fashion therapy for women with non-pathological problems. Previous studies did show if the effect of fashion therapy could be maintained continuously; therefore, we intend to examine the existence of the long-term effects of fashion therapy in an empirical manner and provide implications for social and public interest. This study used a qualitative approach to investigate the effects of fashion therapy with the following results. Low self-esteem, negative emotions, and rigid thinking symptoms appeared by numerous stress factors, and various changes were made through fashion therapy. Emotional changes such as positive emotions and feeling of achievement, and psychological changes including self-concept formation, change of sight and self-esteem improvement appeared. Sociological and behavioral changes were also identified. We found the maintained and long term effects of fashion therapy; therefore, study provides academic implications to reconsider the social value of fashion.

Case Reports : The Effect of Burning Acupuncture Therapy on the Sacroiliac Joint Syndrome (천장관절증후군에 대한 화침(火鍼)치료 1례 보고)

  • Kim, Hyun-Suk;Hong, Seo-Yeong;Oh, Min-Seok
    • Journal of Haehwa Medicine
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    • v.16 no.1
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    • pp.133-138
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    • 2007
  • Objectives : The purpose of this study IS to evaluate the effect of burning acupuncture therapy on the sacroihac Joint syndrome. Methods : This study was carried out on the 1 patient with sacroihac Joint syndrome Subject was treated by acupuncture, negative, burning acupuncture therapy Lumbar ROM and Visual Analog Scale(VAS) were evaluated before and during treatment. Results and Conclusions : VAS was improved 10 to 2 and lumbar Rom was improved In the study, burning acupuncture therapy was effective 10 sacroihac joint syndrome.

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The Effect of Electrical Stimulation on Bacterial Growth (전기자극이 세균성장에 미치는 영향)

  • Park Young-Han;Kim Jin-Sang;Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.6 no.1
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    • pp.109-119
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    • 1994
  • The study was carried out to investigate the change of bacterial growth in vitro according to polarity, current intensity and time, to prepare the basic data for electrotherapy and clinical research. The Gram positive Staphylococcus aureus and Gram negative Escherichia coli 1mm infect wound were cultured in Trypticase Soy Brath and Trypticase Soy Agar. The results were as followings. 1. The current stimulated group was changed in bacterial growth according to polarity, current intensity and time respectively. 2. The bacteriolytic effect revealed in the anode but the inhibitory effect of bacterial growth revealed in the cathode. 3. The lumber of E. coli reduced after 6-hours but the numbers of S. aureus reduced after 2 hours in Trypticase Soy Brath. 4. The anode showed acid reaction and cathode showed alkaline reaction in Trypticase Soy Agar.

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Play Therapy for abused brother and sister (피학대 남매아동을 위한 놀이치료)

  • Choi, Jung-Mi
    • Korean Journal of Human Ecology
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    • v.17 no.5
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    • pp.915-925
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    • 2008
  • This research is based on two cases study of brother and sister who experienced difficulties due to their parent's abuse. The brother and sister play therapy was conducted for sixteen sessions. Each of the therapy and the activity sessions ran 90 minutes weekly. The purpose of this study is to decrease problematic behaviors and to improve self-confidence of abused brother and sister. As a result, the brother's and sister's self-confidence lowered by past negative experiences has been improved, poor social relationship patterns have changed and need for growth as a good person has arisen. The results of research indicate the effectiveness of play therapy to abused brother and sister.

Effects of Group Art Therapy Program on Body Image and Self-esteem in College Women (집단미술요법이 여대생의 신체상과 자존감에 미치는 영향)

  • 정길수;이성은
    • Journal of Korean Academy of Nursing
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    • v.32 no.5
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    • pp.743-755
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    • 2002
  • The purpose of the study was to determine the effects of the 8-week, 16-session group art therapy program on body image and self-esteem in college women. Method: Data collected by self-reported questionnaires from 58 college women in Inchon who were selected by criteria of this study, from the 6 of March to 10 of May, 2002. The 11 experimental group participated in a 8-week group art therapy program. Descriptive statistics, homogeneity test, hypothesis, and reliability test were performed statistically by utilizing SPSS PC+ 8.0 program. Result: 1. 'The experimental group showed significantly higher scores in body image than the comparison group. 2. No significant differences were found between two groups in self-esteem. Conclusion: The findings showed the possibility of applying group art therapy as an effective intervention for clients with negative body image to improve their body image.

Postoperative Infection Caused by Methicillin-Resistant Coagulase-Negative Staphylococci in the Oral and Maxillofacial Region: A Case Report

  • Lee, Hye-Jung;You, Jae-Seak
    • Journal of Oral Medicine and Pain
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    • v.45 no.1
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    • pp.17-21
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    • 2020
  • Osteomyelitis of the jaw infected with Coagulase-Negative Staphylococci (CNS) is rarely reported in the Oral and Maxillofacial Region. Staphylococcus is a part of the normal body flora, but it may be cause severe infections and CNS are often described as the important pathogens in nosocomial infections. Although many studies on prevalence and antibiotics of Staphylococcus aureus have been done, but many of these studies focus only on Methicillin-resistant S. aureus and not on methicillin-resistant coagulase-negative Staphylococci (MRCNS). There was a less study about CNS or MRCNS infections in the Oral and Maxillofacial Region. This report describes a case of a 41-year-old male patient who developed osteomyelitis caused by MRCNS on condyle after open reduction and internal fixation and suggests guideline for the prevention of postoperative infection and appropriate recommendation for treatment and control.

The study on relationship between body and self-belief and methods of self-therapy in transcendental meditation (명상수련에 있어서의 몸과 신념의 관계 및 자기치유 방법에 대한 소고)

  • Ryu, In seon;Kim, Yoon sik;Seol, In chan
    • Journal of Haehwa Medicine
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    • v.13 no.1
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    • pp.97-105
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    • 2004
  • In the Oriental medicine, it was recognized that mind and body have a inseparable relationship. The goal of this study was to examine the body(肉體) and self-be1ief(自己信念) and methods of self-therapy(自己治癒) in transcendental meditation(冥想療法). We will furnish the information of the basic concepts and methods in transcendental meditation. The findings are as follows: 1. The thing that you have in mind does not stay in abstract idea but materializes and operates the body. 2. When you have disease implies that you have negative belief, thought and mind. 3. When you can observe the things happening in your body and mind- just like meditation- you can have positive changes. 4. When you change the negative beliefs into positive ones on body, you feel gratitude and the disease will be cured.

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Bacteriology and Antibiotic Sensitivity for Diabetic Foot Ulcer (당뇨족 궤양의 세균 역학과 항생제 감수성)

  • Choi, Sang-Rok;Lee, Chang-Kyu;Kim, Deok-Woo;Han, Seung-Kyu;Kim, Woo-Kyung
    • Archives of Plastic Surgery
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    • v.33 no.3
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    • pp.330-334
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    • 2006
  • Polymicrobial nature of diabetic foot infection has been well documented in the literature. Initial antibiotic therapy of diabetic foot infection is usually empiric until reliable culture data is shown. This study was carried out to determine the common bacteriological flora of diabetic foot infection and antimicrobial sensitivity pattern in order to enhance possible empiric treatment. The specimens were obtained from wounds of 207 cases of diabetic foot ulcer, and the bacteriological isolation, and antimicrobial susceptibility tests of the isolates were carried out by standard microbiological methods. Staphylococcus aureus was the most common isolate, with 46.2% of recover rate among total bacterial isolated cases. Among gram-negative organisms, Pseudomonas aeruginosa was most common. Gram-positive organisms showed significant susceptibility to clindamycin, trimethoprim/sulfamethoxazole, and levofloxacin, besides vancomycin. Cefoperazone, piperacillin/tazobactam, and amikacin in addition to imipenem were most effective agents compared to gram-negative organisms. Diabetic foot infection requires use of combined antimicrobial therapy for initial management. Our results indicate that the most effective antibiotic combination for diabetic foot infection of Korean patients is clindamycin plus cefoperazone.

The Effectiveness of Mindfulness-Based Cognitive Therapy-Korean (MBCT-K) for Anxiety and Depression in Patients with Anxiety Disorder (한국형 마음챙김 명상에 기초한 인지 치료가 불안 장애 환자의 불안과 우울에 미치는 효과 비교)

  • Shin, Nayeon
    • Journal of Digital Policy
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    • v.1 no.1
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    • pp.1-5
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    • 2022
  • The objective of this study was to examine the effectiveness of newly developed program for the recovery and relapse prevention in patients with anxiety disorder. Twenty-four patients with anxiety disorder received Mindfulness-Based Cognitive Therapy (MBCT) session weekly for a period of overall 8 weeks-program. Changes of depression, anxiety, negative and positive automatic thought were compared before and after the program. Depression and anxiety were improved significantly after the MBCT program(Z=-1.9, p=.06, Z=-2.9, p<.001). Conclusions: MBCT may be effective at reducing negative automatic thought and relieving anxiety and depressive symptoms in patients with anxiety disorder. However, large-sample, randomized controlled trials will be needed for generalization.