• Title/Summary/Keyword: Negative Side-Effects

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Health Food Intake and Behavioral Intentions to Take Health Food on Male Workers by Practiced Health Behavior in Seoul (서울 남자 직장인의 건강행위실천별 건강식품 섭취 행동 의도 및 영향 요인)

  • Rhie, Seung-Gyo
    • The Korean Journal of Community Living Science
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    • v.21 no.2
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    • pp.243-257
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    • 2010
  • This study was conducted to search the health food intake behavioral intentions of male workers. The health-related behavior of 150 subjects were compared(smoke, alcohol drink, breakfast, BMI, sleep, exercise and health check). On the basis of the Theory of Planned Behavior, the factors health-food intake behavior were evaluated; there were normative beliefs, motivation for compliance, subjective norms, social influence factors, and barriers as perceived behavior control. The results were showed with five points by the Likert scale and Significance by t-test. The most frequently consumed health food was tea(3.40/4points) followed by healthy drinks(2.49/4). As behavioral beliefs, if consumption of 'nutritional supplements'(3.61/5) and 'fatigue recovery'(3.62/5) received the highest scores. As a result, the idea of 'nutritional supplements'(3.94/5) and 'fatigue recovery'(4.06/5) were the important aspects, but others were also positively evaluated. As a sub-factor of subjective norms on normative beliefs, The highest social groups to encourage consumption of health food were parents (3.93/5), and the lowest were doctors (3.02/5). The most influential people were doctors (3.67/5) and spouses (3.65/5). Barriers to consumption health food were side effects (1.09/5) and price (2.08/5). Taking Ginseng products and other processed foods (juice, honey, bamboo, etc.) were correlated with health concern (p<0.05). Taking traditional stamina foods was correlated with dietary habit recognition (p<0.05). Mineral intake was positively correlated with age. Healthy drinks was negative (p<0.05). Minerals and supplement consumption were correlated with the practice of healthy behavior (p<0.01).

Large eddy simulation of flow around a stay cable with an artificial upper rivulet

  • Zhao, Yan;Du, Xiaoqing;Gu, Ming;Yang, Xiao;Li, Junjun;He, Ping
    • Wind and Structures
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    • v.26 no.4
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    • pp.215-229
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    • 2018
  • The appearance of a rivulet at the upper surface of a stay cable is responsible for rain-wind-induced vibration (RWIV) of cables of cable-stayed bridges. However, the formation mechanism of the upper rivulet and its aerodynamic effects on the stay cable has not been fully understood. Large eddy simulation (LES) method is used to investigate flow around and aerodynamics of a circular cylinder with an upper rivulet at a Reynolds number of 140,000. Results show that the mean lift coefficients of the circular cylinder experience three distinct stages, zero-lift stage, positive-lift stage and negative-lift stage as the rivulet located at various positions. Both pressure-induced and friction-induced aerodynamic forces on the upper rivulet are helpful for its appearance on the upside of the stay cable. The friction-induced aerodynamic forces, which have not been considered in the previous theoretical models, may not be neglected in modeling the RWIV. In positive-lift stage, the shear layer separated from the upper rivulet can reattach on the surface of the cylinder and form separation bubbles, which result in a high non-zero mean lift of the cylinder and potentially induces the occurrence of RWIV. The separation bubbles are intrinsically unsteady flow phenomena. A serial of small eddies first appears in the laminar shear layer separated from the upper rivulet, which then coalesces and reattaches on the side surface of the cylinder and eventually sheds into the wake.

Preemptive Use of Ketamine on Post Operative Pain of Appendectomy

  • Behdad, Akbar;Hosseinpour, Mehrdad;Khorasani, Parastoo
    • The Korean Journal of Pain
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    • v.24 no.3
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    • pp.137-140
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    • 2011
  • Background: Although early reviews of clinical findings were mostly negative, there is still a widespread belief for the efficacy of preemptive analgesia among clinicians. In this study, we evaluated whether the preemptive use of ketamine decreases post operative pain in patients undergoing appendectomy. Methods: In double-blind, randomized clinical trials, 80 adult male patients undergoing an operation for acute appendicitis were studied. Patients were randomly assigned to two groups. In the operating room, patients in the ketamine group received 0.5 mg/kg of ketamine IV 10 minutes before the surgical incision. In the control group, 0.5 mg/kg of normal saline was injected. The pain intensity was assessed at time 0 (immediately after arousal) and 4, 12, and 24 hours postoperatively using the 10 points visual analogue scale (VAS). Results: Eighty patients (40 for both groups) were enrolled in this study. For all of the evaluated times, the VAS score was significantly lower in the ketamine group compared to the control. The interval time for the first analgesic request was $23.1{\pm}6.7$ minutes for the case group and $18.1{\pm}7.3$ minutes for the control (P = 0.02). The total number of pethidine injections in the first 24 hours postoperatively was $0.6{\pm}0.6$ for the case group and $2.0{\pm}0.8$ for the controls (P = 0.032). There were no drug side effects for the case group. Conclusions: A low dose of intravenously administered ketamine had a preemptive effect in reducing pain after appendectomy.

The Effect of Visual Display Terminal Work on the Human Body (영상화면 단말기(VDT)작업이 인체에 미치는 영향)

  • 이호찬;박용억;강회향;민경진;김종규
    • Journal of Environmental Health Sciences
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    • v.21 no.4
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    • pp.75-86
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    • 1995
  • This study was performed to investigate the negative side effects of video display terminal (VDT) work on the human body and to provide data for preventing VDT syndrome. A questionnaire survey was made to 339 VDT workers at 22 offices in Taegu, Kyungpook and Kyungnam areas from July 1 to August 31, 1994, and 280 of them were finally used for statistical analysis. The VDT syndrome in the present study inclhded five factors, namely as eye-related symptom, psychological symptom, general body symptom, musculoskeletal symptom, and skin-related symptom, and the estimates of Crombach coefficients of the five factors were 0.954, 0.952, 0.953, 0.957, and 0.955, respectively, showing very high reliability. In view of socio-economical characteristics, the symptoms of female were higher than those of male in the order of musculoskeletal symptom, eye-related symptom, skin-related symptom and psychological symptom. The age group of 30 years or less was higher than the older groups in the order of musculoskeletal symptom, eye-related symptom, psychological symptom and skinrelated symptom. The group of lower education level showed higher skin-related symptom. The psychological symptom and skin-related symptom increased as the amount of smoking increased. Higher eye-related symptom was observed in the group without glasses. In the job-related variables, the group of working on programming and data input showed higher eye-related symptom and psychological symptom. The group of working on programming and graphic design showed higher musculoskeletal symptom and skin-related symptom. The skin-related symptom increased as the total time of VDT operation per day increased. The group of working 2-4 hours followed by 15 minutes rest was higher in musculoskeletal symptom and psychological symptom. Higher musculoskeletal symptom was observed from the group working on Friday and Sunday. The group of 1 year or less working showed higher in skin-related symptom. In relation with the VDT type, all symptoms except skin-related symptom were higher in the group using monochrome monitor. As showed above, the questionnaire could be a tool for evaluating VDT syndrome and prevention of the syndrome would be possible by a comprehensive consideration of factors including socio-economic characteristics, job-related variables and VDT type.

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Differential Roles of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Angiogenesis

  • Shibuya, Masabumi
    • BMB Reports
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    • v.39 no.5
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    • pp.469-478
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    • 2006
  • Vascular endothelial growth factor (VEGF)-A, a major regulator for angiogenesis, binds and activates two tyrosine kinase receptors, VEGFR1 (Flt-1) and VEGFR2 (KDR/Flk-1). These receptors regulate physiological as well as pathological angiogenesis. VEGFR2 has strong tyrosine kinase activity, and transduces the major signals for angiogenesis. However, unlike other representative tyrosine kinase receptors which use the Ras pathway, VEGFR2 mostly uses the Phospholipase-$C{\gamma}$-Protein kinase-C pathway to activate MAP-kinase and DNA synthesis. VEGFR2 is a direct signal transducer for pathological angiogenesis including cancer and diabetic retinopathy, thus, VEGFR2 itself and the signaling appear to be critical targets for the suppression of these diseases. VEGFR1 plays dual role, a negative role in angiogenesis in the embryo most likely by trapping VEGF-A, and a positive role in adulthood in a tyrosine kinase-dependent manner. VEGFR1 is expressed not only in endothelial cells but also in macrophage-lineage cells, and promotes tumor growth, metastasis, and inflammation. Furthermore, a soluble form of VEGFR1 was found to be present at abnormally high levels in the serum of preeclampsia patients, and induces proteinurea and renal dysfunction. Therefore, VEGFR1 is also an important target in the treatment of human diseases. Recently, the VEGFR2-specific ligand VEGF-E (Orf-VEGF) was extensively characterized. Interestingly, the activation of VEGFR2 via VEGF-E in vivo results in a strong angiogenic response in mice with minor side effects such as inflammation compared with VEGF-A, suggesting VEGF-E to be a novel material for pro-angiogenic therapy.

Effect of flexion degrees in elbow joint on muscle activation of the extensor carpi radialis and biceps brachii muscles in healthy young adults

  • Kim, Gap-Cheol;Hwang, Sujin
    • Physical Therapy Rehabilitation Science
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    • v.5 no.3
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    • pp.120-124
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    • 2016
  • Objective: Chronic lateral epicondylitis is a condition which becomes sore and tender on the lateral side of the elbow joint damaged from overuse and repetitive use of the extensor muscles of the forearm. The purpose of this study was to investigate the effects of flexion degrees in the elbow joint on extensor carpi radialis longus and brevis and biceps brachii muscles in individuals with healthy young adults. The main purpose of this study was to suggest the feasibility of optimal elbow angle during therapeutic eccentric exercise with resistance for strengthening of wrist extensors. Design: Cross-sectional study. Methods: Thirty health young adults (male 15, female 15) participated in this study. This study measured muscle activation in four different conditions of elbow flexion, $0^{\circ}$, $30^{\circ}$, $60^{\circ}$, and $90^{\circ}$ during eccentric exercise with weight loading in wrist extensors, extensor carpi radialis longus and brevis and biceps brachii muscles using surface electromyography. Results: The muscle activation of extensor carpi radialis showed a negative relationship with the degrees of elbow joint flexion. With increasing elbow flexion angles, the ECRL muscle activation amount was significantly lower (p<0.05). In contrast, the muscle activation of the ECRB muscle activation amount was significanlty higher (p<0.05). Conclusions: This study suggests that the eccentric exercise of wrist extension with selected activation of wrist extensor muscles according to elbow flexion positions, and suggests that the extensor carpi radialis longus and brevis will need to be strengthened for preventing and treating chronic lateral epicondylitis regardless of degrees of elbow joint flexion.

Emotional Intelligence of Youth Impacted by the Used Time of Smart Devices and Sports Activities (스마트 기기 사용 시간과 스포츠 활동 시간이 청소년의 감성지능에 미치는 영향)

  • Kwon, Mee-Rhan
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.14 no.1
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    • pp.211-217
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    • 2014
  • The smart revolution led by Smart Phone in our daily lives is changing the paradigm in general. These smart revolution has provided us a lot of convenience, but on the other hand also appearing an inverse function. The host of the future of young people, especially by the excessive use of smart devices, there is a risk of side effects increased. In this study, the empirical analysis has been done to know how the used time of smart devices and youth sports activities affect to the emotional intelligence. Using regression analysis, the used time of smart devices showed negative relationship and the time of youth sports activities affected positively with the emotional intelligence. Additional analysis of the amount of reading also affected positively to the motional intelligence as a conclusion. Through this study, as a conclusion, traditional activities, namely sports activities and reading to help the youth developing emotional intelligence, while the use of smart devices inhibits the development of emotional intelligence of youth.

Current Issues and Future Considerations in Undergraduate Medical Education from the Perspective of the Korean Medical Doctor Development System (우리나라 의사양성체제의 관점에서 본 의과대학 교육의 문제점과 개선방향)

  • Han, Jae Jin
    • Korean Medical Education Review
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    • v.20 no.2
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    • pp.72-77
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    • 2018
  • Observation of the current Korean medical education and training system shows that certain negative traits of unchangeable solidification engraft themselves so deeply into the overarching system that they are now hampering the state of the national health welfare. Focusing only on undergraduate medical education, we can point out some glaring side-effects that should be of concern to any stakeholder. For instance, a graduate can legally begin his career as an independent practitioner immediately after passing the licensing exam and return to the old stuck school-year system of 2-year-premedical and 4-year-medical programs where outcome-based and integrated curricula are incomplete and unsatisfactory. In terms of learning opportunities, the balance between patient care and public health, as well as that between in-hospital highly specialized practice and community-based general practice, has worsened. Every stakeholder should be aware of these considerations in order to obtain the insight to forge a new direction. Moreover, our medical schools must prepare our students to take on the global roles of patient care within the Fourth Industrial Revolution, health advocacy for the imminent super-aged society, and education and research in the bio-health industry, by building and applying the concept of academic medicine. We will need to invest more resources, including educational specialists, into the current undergraduate medical education system in order to produce proper outcomes, smart curriculum, innovative methods of teaching and learning, and valid and reliable monitoring and evaluation. The improved quality of undergraduate medical education is the starting point for the success of the national system for public health and medical care as a whole, and therefore its urgency and significance should be emphasized to the public. The medical society should go beyond fixing what is broken and usher in a new era of cooperation and collaboration that invites other health professionals, governmental partners, law-makers, opinion leaders, and the general public in its steps toward the future.

Functioning of the Geoecosystem for the West Side of Admiralty Bay (King George Island, Antarctica): Outline of Research at Arctowski Station

  • Rakusa-Suszczewski, Stanislaw
    • Ocean and Polar Research
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    • v.25 no.4
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    • pp.653-662
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    • 2003
  • Changes in the area of geo-ecosystem $(62^{\circ}09'S,\;58^{\circ}31'w)$ reflect climatic changes in the South Shetland Islands. Air temperature and deglaciation will increase. The ice-free space area at the SSSS 8- (ASPA 121) site has enlarged threefold during the last 21 years, thus creating conditions for inhabitation and succession. Wind, water and snow play important roles in transportation of geochemical components. They distribute nutrients, mineral substances, seeds, fragments of plants and animals, etc. Plant and animal colonization is patchy and it happens at random in an 'island' - like manner. The colonization pattern is dependant, to a high degree on physical factors. The newly uncovered ice-free areas are at first inhabited by a vascular plant known as the Deschampsia antarctica. The border of the land-oasis with Admiralty Bay is the place where the processes related to animal feeding at the sea and reproduction on the land take place. Bird colonies and pinniped lairs form centers of fertilization surrounded by high chemical gradients dependent on the direction of the flow of nutrients $(e.g.\;NH_4)$. During the last 25 years, the numbers of penguins in this region have decreased, and thus the amount of materials excreted on land has diminished. The numbers of fur seals change in multi-annual cycles, and their migration into this area is related to the E1 $Ni\~{n}o$ phenomenon. The numbers of elephant seals in the area did not change. Organic matter deposited by the sea onto the shore are a source of nutrients and deficient chemical elements on land. Mineral matter is washed out into the waters of Admiralty Bay. These processes change seasonally, and multi annually. Negative effects on the environment at Arctowski Station induced by man are slight, but noticeable nevertheless. Physical processes have the largest influence on the living conditions and distribution of plants and animals, and as a consequence, on the functioning of the geo-ecosystem in the coastal-shore zone of the Maritime Antarctic.

The Usefulness of the Ivy Sign on Fluid-Attenuated Intensity Recovery Images in Improved Brain Hemodynamic Changes after Superficial Temporal Artery-Middle Cerebral Artery Anastomosis in Adult Patients with Moyamoya Disease

  • Lee, Jung Keun;Yoon, Byul Hee;Chung, Seung Young;Park, Moon Sun;Kim, Seong Min;Lee, Do Sung
    • Journal of Korean Neurosurgical Society
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    • v.54 no.4
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    • pp.302-308
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    • 2013
  • Objective : MR perfusion and single photon emission computerized tomography (SPECT) are well known imaging studies to evaluate hemodynamic change between prior to and following superficial temporal artery (STA)-middle cerebral artery (MCA) anastomosis in moyamoya disease. But their side effects and invasiveness make discomfort to patients. We evaluated the ivy sign on MR fluid attenuated inversion recovery (FLAIR) images in adult patients with moyamoya disease and compared it with result of SPECT and MR perfusion images. Methods : We enrolled twelve patients (thirteen cases) who were diagnosed with moyamoya disease and underwent STA-MCA anastomosis at our medical institution during a period ranging from September of 2010 to December of 2012. The presence of the ivy sign on MR FLAIR images was classified as Negative (0), Minimal (1), and Positive (2). Regions were classified into four territories: the anterior cerebral artery (ACA), the anterior MCA, the posterior MCA and the posterior cerebral artery. Results : Ivy signs on preoperative and postoperative MR FLAIR were improved (8 and 4 in the ACA regions, 13 and 4 in the anterior MCA regions and 19 and 9 in the posterior MCA regions). Like this result, the cerebrovascular reserve (CVR) on SPECT was significantly increased in the sum of CVR in same regions after STA-MCA anastomosis. Conclusion : After STA-MCA anastomosis, ivy signs were decreased in the cerebral hemisphere. As compared with conventional diagnostic modalities such as SPECT and MR perfusion images, the ivy sign on MR FLAIR is considered as a useful indicator in detecting brain hemodynamic changes between preoperatively and postoperatively in adult moyamoya patients.