• Journal of the Korean Institute of Oriental Medical Informatics
• /
• v.14 no.2
• /
• pp.79-93
• /
• 2008

Objectives : Taichi for arthritis was developed in 1997 by Paul Lam, M.D. of family medicine in Australia. It is an exercise treatment program and a good approaching method of the oriental medicine for arthritis. However, clinical and academical researches were rare. The purpose of this study is to investigate the effectiveness of the Taichi for arthritis. Methods : We used the medical literature search system, MEDLIS and the database of academic journal, DBpia to search medical studies published in korea. Keywords were "Taichi", "Tai Chi Chuan" and "Arthritis". We classified literatures with two criteria, year of publishment and study design. Then we classified as placebo design and summarized whole material. We determined its effectiveness by positive-negative results of Taichi for arthritis. Results : Taichi for arthritis could release pain of the rheumatoid or degenerative arthritis. Also it is thought to increase muscular power and enhance physical flexibility, balance. Conclusions : There were limits to ensure effectiveness because of small number of studies comparing Taichi with other exercise program for arthritis. However the Taichi for arthritis could have positive effect to treat the rheumatoid and degenerative arthritis. We hope further studies to be followed in oriental medical field.

• Safety and Health at Work
• /
• v.10 no.4
• /
• pp.393-399
• /
• 2019

Objective: This study investigates the impact of multimorbidity on work through a literature review of longitudinal studies. Methods: A systematic review was carried out in the databases Lilacs, SciELO, PAHO, PubMed/Medline, Scopus, Web of Science, and Cochrane. There were no restrictions regarding the year of publication or language to maximize the identification of relevant literature. The quality of studies was assessed by the protocol STrengthening the Reporting of OBservational studies in Epidemiology (STROBE). Results: An initial database search identified 7522 registries, and at the end of the analysis, 7 manuscripts were included in the review. Several studies have demonstrated direct and indirect impacts of multimorbidity on the health of workers. For this, the number of missed days due to health-related issues was evaluated, as well as the reduction in work productivity of the unhealthy worker, vulnerability of the worker with multimorbidity regarding higher indices of dismissal and recruitment difficulties, and incidence of early retirement and/or receipt of benefits due to disabilities. Conclusions: Multimorbidity has a negative impact on work, with damages to quality of life and work productivity, worsening the absenteeism/presenteeism indices, enhancing the chances of temporary or permanent leaves, and lowering employability and admission of individuals with multimorbidity.

• Journal of the Korea Society of Computer and Information
• /
• v.15 no.1
• /
• pp.149-157
• /
• 2010

As the use of the Internet has recently increased, the demand for opinion information posted on the Internet has grown. However, such resources only exist on the website. People who want to search for information on the Internet find it inconvenient to visit each website. This paper focuses on the opinion information extraction and analysis system through Web mining that is based on statistics collected from Web contents. That is, users' opinion information which is scattered across several websites can be automatically analyzed and extracted. The system provides the opinion information search service that enables users to search for real-time positive and negative opinions and check their statistics. Also, users can do real-time search and monitoring about other opinion information by putting keywords in the system. Proposed technologies proved to have outstanding capabilities in comparison to existing ones through tests. The capabilities to extract positive and negative opinion information were assessed. Specifically, test movie review sentence testing data was tested and its results were analyzed.

• The Journal of the Society of Korean Medicine Diagnostics
• /
• v.17 no.1
• /
• pp.1-16
• /
• 2013

Objectives Iridology is a field of study that diagnoses various systemic diseases through analysis of colors, structural characteristics and changes in iris. The purpose of this study was to review previously published study results of the iridology. Methods The studies were searched with the keyword "iridology" through search engines such as SCOPUS, Pub med, RISS, and NDSL. Total of 36 iridology-related studies published from 1980 to 2012 were analyzed. Results Most diagnoses of systemic disease through iris markings were insignificant. The studies on relevance of gene polymorphism and iris constitution were highly significant. The studies on relevance of Sasang constitution and iris constitution varied in results depending on diagnosis methods. The studies on relevance of iris constitution and diseases had significant results. The structural characteristics of iris were related to certain personality. Conclusions The studies on utility of iris diagnosis and diagnostic markings were negative, but the relevance of constitution, heredity, and iris diagnosis was positive. A persistent in-depth study on relevance of iris and constitution is needed in the future.

• Journal of Microbiology and Biotechnology
• /
• v.14 no.1
• /
• pp.1-14
• /
• 2004

More than twenty years have passed since the approval of the first recombinant DNA product for therapeutic use (recombinant human insulin, 1982). However, the biotechnology industry is still facing a shortage of manufacturing capacity due to the increasing demand of therapeutic proteins. This demand has prompted the search for a growing number of biological production systems but, nevertheless, the Gram-negative bacterium Escherichia coli remains one of the most attractive production hosts. This review highlights the most important features and developments of plasmid vector design, emphasizing the different reported strategies for improving the expression and secretion of heterologous proteins using the cellular machinery of E. coli.

• Journal of Embryo Transfer
• /
• v.33 no.1
• /
• pp.49-54
• /
• 2018

Adenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain unclear. This paper summarizes the reports found in the MEDLINE database on the molecular mechanisms involved in the development and progression of uterine adenomyosis. The literature search included the following terms: "adenomyosis," "adenomyoma," "pathogenesis," "molecular mechanisms," and "gynecological disorders." Only peer-reviewed, English-language journal articles were included. This review focuses on the molecular genetics, epigenetic modifications, and pivotal signaling pathways associated with adenomyosis development and progression, which will provide insights into and a better understanding of its underlying pathophysiology.

• Journal of Korean Neurosurgical Society
• /
• v.47 no.1
• /
• pp.64-67
• /
• 2010

Although very rare, a few cases of intradural extramedullary (IDEM) spinal tumor migration have been reported since Tomimatsu first reported a mobile schwannoma of the cervical cord in 1974. Schwan noma is a neurogenic tumor which originates from nerve sheath that it is relatively well-marginated tumor with little attachment or adhesion to surrounding tissue. Mobility of tumor in spinal canal sometimes can result in negative exploration at the expected area. We found three interesting cases in which different tumor locations observed in repeated magnetic resonance image (MRI) findings. All tumors were intradural and extramedullary schwannoma. We reviewed the literature about moving tumor in the spine through PUBMED search.

• Journal of Korean Academy of Nursing
• /
• v.50 no.3
• /
• pp.349-368
• /
• 2020

Purpose: This study aimed to identify parental factors associated with smartphone overuse in preschoolers. Methods: A systematic review was conducted according to PRISMA guidelines. Relevant studies published in peer-reviewed journals from 2009 to June 2019 were identified through systematic search in 10 electronic databases (PubMed, CINAHL, Cochrane Central, EMBASE, Web of Science, NDSL, KISS, KMbase, KoreaMed, and RISS). Standardized effect sizes were calculated to quantify the associations of parental factors with smartphone overuse in preschoolers using meta-analysis. Results: A total of 30 cross-sectional studies involving 7,943 participants met the inclusion criteria. The following were negatively correlated with smartphone overuse in preschoolers: mother's parenting self-efficacy (r=-.35), mother-child attachment (r=-.28), mother's positive parenting behavior (r=-.28), mother's positive parenting attitude (r=-.25), and father's parenting involvement (r=-.15). Further, maternal factors such as smartphone addiction tendency (r=.41), parenting stress (r=.40), negative parenting behavior (r=.35), negative parenting attitude (r=.14), smartphone usage time (r=.26), employment status (r=.18), and age (r=.12) were positively correlated with smartphone overuse in preschoolers. Conclusion: Several parental factors influence smartphone overuse in preschoolers. These findings emphasize the need to assess and enhance the parental factors identified in this study to prevent smartphone overuse in preschoolers. Accordingly, we recommend the development of preventive interventions to strengthen parent-related protective factors and mitigate risk factors.

• The Journal of Korean Medicine
• /
• v.42 no.1
• /
• pp.99-109
• /
• 2021

Objectives: Objective: The purpose of this study is to investigate the treatment of herbal medicine for patients with COVID-19 asymptomatic infections. Method: In English, search engines such as 'PubMed', 'Science Direct', and 'Cumulative Index to Nursing and Allied Health Literature (CINAHL)' were used. In Chinese, search engines such as 'China National Knowledge Infrastructure (CNKI)' and Wanfang were used. The keywords for the search engines were 'COVID-19', 'asymptomatic infection', 'Korean Medicine', 'traditional Chinese medicine', 'herbal medicine', and etc. Only clinical studies using herbal medicine for patients without fever or respiratory symptoms were selected. We excluded the cases that do not fit the research topic. Results: A total of 5 studies were finally selected. Among them, four of them used integrated herbal medicine and Western medicine, and one of the studies treated exclusively for herbal medicine. There were a total of seven prescriptions for herbal medicine used in the study. Outcome variables were used as following: lab test, nucleic acid conversion time, hospitalization period, chest CT, and etc. In the RCT study, herbal medicine and Western medicine decreased nucleic acid conversion time, average hospitalization time compared to the control group, but it was not statistically significant. No other adverse reactions were reported in all studies. Conclusion: According to the results, integrated herbal medicine and Western medicine might be an effective treatment for patients with COVID-19 asymptomatic infection reducing hospitalization period, time of nucleic acid turning negative. No severe adverse effects were reported. However, it is thought that better-designed research will be needed in the future.

• Safety and Health at Work
• /
• v.8 no.2
• /
• pp.143-150
• /
• 2017

A huge number of chemicals are produced and used in the world, and some of them can have negative effects on the reproductive health of workers. To date, most chemicals and work environments have not been studied for their potential to have damaging effects on the workers' reproductive system. Because of the lack of information, many workers may not be aware that such problems can be related to occupational exposures. Newly industrialized countries such as Republic of Korea have rapidly amassed chemicals and other toxicants that pose health hazards, especially to the reproductive systems of workers. This literature review provides an overview of peer-reviewed literature regarding the teratogenic impact and need for safe handling of chemicals. Literature searches were performed using PubMed, Google Scholar, and ScienceDirect. Search strategies were narrowed based on author expertise and 100 articles were chosen for detailed analysis. A total of 47 articles met prespecified inclusion criteria. The majority of papers contained studies that were descriptive in nature with respect to the Medical Subject Headings (MeSH) terms and keywords: "reproductive and heath or hazard and/or workplace or workers or occupations." In the absence of complete information about the safe occupational handling of chemicals in Republic of Korea (other than a material safety data sheet), this review serves as a valuable reference for identifying and remedying potential gaps in relevant regulations. The review also proposes other public health actions including hazard surveillance and primary prevention activities such as reduction, substitution, ventilation, as well as protective equipment.