Objective : Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, neurointerventionists have been increasingly concerned regarding the prevention of infection and time delay in performing emergency thrombectomy procedures in patients with acute stroke. This study aimed to analyze the effects of changes in mechanical thrombectomy protocol before and after the COVID-19 pandemic on procedure time and patient outcomes and to identify factors that significantly impact procedure time. Methods : The last-normal-to-door, first-abnormal-to-door, door-to-imaging, door-to-puncture, and puncture-to-recanalization times of 88 patients (45 treated with conventional pre-COVID-19 protocol and 43 with COVID-19 protection protocol) were retrospectively analyzed. The recanalization time, success rate of mechanical thrombectomy, and modified Rankin score of patients at discharge were assessed. A multivariate analysis was conducted to identify variables that significantly influenced the time delay in the door-to-puncture time and total procedure time. Results : The door-to-imaging time significantly increased under the COVID-19 protection protocol (p=0.0257) compared to that with the conventional pre-COVID-19 protocol. This increase was even more pronounced in patients who were suspected to be COVID-19-positive than in those who were negative. The door-to-puncture time showed no statistical difference between the conventional and COVID-19 protocol groups (p=0.5042). However, in the multivariate analysis, the last-normal-to-door time and door-to-imaging time were shown to affect the door-to-puncture time (p=0.0068 and 0.0097). The total procedure time was affected by the occlusion site, last-normal-to-door time, door-to-imaging time, and type of anesthesia (p=0.0001, 0.0231, 0.0103, and 0.0207, respectively). Conclusion : The COVID-19 protection protocol significantly impacted the door-to-imaging time. Shortening the door-to-imaging time and performing the procedure under local anesthesia, if possible, may be required to reduce the door-to-puncture and door-to-recanalization times. The effect of various aspects of the protection protocol on emergency thrombectomy should be further studied.
Journal of Korean Tunnelling and Underground Space Association
/
v.23
no.6
/
pp.403-421
/
2021
Most of the urban tunnels in Korea, which are represented by the 1st to 3rd subways, use the drainage tunnel by NATM. Recently, when a construction project that actively utilizes large-scale urban space is promoted, negative effects that do not conform to the existing empirical rules of urban tunnels may occur. In particular, there is a high possibility that groundwater fluctuations and hydrodynamic behavior will occur owing to the practice of tunnel technology in Korea, which has mainly applied the drainage tunnel. In order to solve the problem of the drainage tunnel, attempts are being made to control groundwater fluctuations. For this, the establishment of tunnel groundwater management standard concept and the analysis of the tunnel hydraulic behavior were performed. To prevent the problem of groundwater fluctuations caused by the construction of large-scale tunnels in urban areas, it was suggested that the conceptual transformation of the empirical technical practice, which is applied only in the underground safety impact assessment stage, to the direction of controlling the inflow in the tunnel, is required. And the relationship between the groundwater level and the inflow of the tunnel required for setting the allowable inflow when planning the tunnel was derived. The introduction of a tunnel groundwater management concept is expected to help solve problems such as groundwater fluctuations, ground settlement, depletion of groundwater resources, and decline of maintenance performance in various urban deep tunnel construction projects to be promoted in the future.
Objective: The aim of the study was to evaluate the influence of gene polymorphisms and nongenetic factors on the somatic cell score (SCS) in the milk of Holstein (n = 148) and Simmental (n = 73) cows and their crosses (n = 6). Methods: The SCS was calculated by the formula SCS = log2(SCC/100,000)+3, where SCC is the somatic cell count. Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3), beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the cow's milk was performed. Further, the impact of breed, farm, year, month of the year, lactation stage and parity on the SCS were analysed. Phenotype correlations among SCS and milk constituents were computed by Pearson correlation coefficients. Results: Only CSN2 genotypes A1/A2 were found to have significant association with the SCS (p<0.05), and alleles of CSN1S1 and DGAT1 genes (p<0.05). Other polymorphisms were not found to be significant. SCS had significant association with the combined effect of farm and year, lactation stage and month of the year. Lactation parity and breed had not significant association with SCS. The phenotypic correlation of SCS to lactose content was negative and significant, while the correlation to protein content was positive and significant. The correlations of SCS to fat, casein, nonfat solids, urea, citric acid, acetone and ketones contents were very low and not significant. Conclusion: Only CSN2 genotypes, CSN1S1 and DGAT1 alleles did show an obvious association to the SCS. The results confirmed the importance of general quality management of farms on the microbial milk quality, and effects of lactation stage and month of the year. The lactose content in milk reflects the health status of the udder.
The development of digital technology has made consumers more knowledgeable about products than ever before. In this regard, experts have defined consumers in the digital age as knowledge seekers and pointed out that they are proficient in acquiring and sharing product knowledge prior to purchase. For service goods such as musicals, product prior knowledge executes strong effect due to such characteristics as intangibility, inseparabilit y,and heterogeneity. Prior studies in the field of performing arts, including musicals, have revealed that the prior knowledge of the audience has a positive effect on the satisfaction of the audience and WOM(word-of-mouth) intention. However, studies in the marketing field argue that consumers' high prior knowledge may have a negative impact on customer satisfaction and product evaluation depending on conditions, as they are more likely to compare, review, and expect products more closely. Therefore, in this study, we tried to identify under what conditions the musical prior knowledge enhances audience satisfaction and WOM intention. According to the results of previous studies, a mediating effect model was established in which the musical prior knowledge enhances the WOM intention through the mediation of the audience satisfaction. Then, Transportation was introduced as a mediation variable and it was verified whether the level changed the audience satisfaction and WOM intention. The reason for the introduction of the transportation construct reflects the results of previous research that the story is important component of musical. The results showed that the musical prior knowledge has a significant effect on WOM intention through the mediation of audience satisfaction. The moderating effect of transport was also significant on the relationship between musical prior knowledge and audience satisfaction. Lastly, through moderated-mediation analysis, it was confirmed that transportation moderates the mediating effect that prior knowledge affects on the WOM intention through audience satisfaction. Based on the results, we demonstrated that a musical story is fairly important to satisfy audiences with high prior knowledge. This study could contribute to the related filed in that it introduced the transportation construct for the first time, thereby broadening the understanding of the musical audiences in the era of smart consumers.
Many studies have proposed several factors that affect review helpfulness. Previous studies have investigated the effect of quantitative factors (e.g., star ratings) and affective factors (e.g., sentiment scores) on review helpfulness. Online reviews contain titles and contents, but existing studies focus on the review content. However, there is a limitation to investigating the factors that affect review helpfulness based on the review content without considering the review title. However, previous studies independently investigated the effect of review content and title on review helpfulness. However, it may ignore the potential impact of similarity between review titles and content on review helpfulness. This study used text consistency between review titles and content affect review helpfulness based on the mere exposure effect theory. We also considered the role of information clearness, review length, and source reliability. The results show that text consistency between the review title and the content negatively affects the review helpfulness. Furthermore, we found that information clearness and source reliability weaken the negative effects of text consistency on review helpfulness.
In this study, we investigate the interrelationship between housing tenure and childbirth by exploiting the correlation probability effect method that accounts for household heterogeneity. Using the newlywed household panel from 2011 to 2022, we find that home ownership has a positive impact on childbirth in newlyweds. Specifically, newlywed households with housing tenure show a 6.2%p higher birth rate and a 5.7%p higher second childbirth than newlywed households living in rented houses. For the case of first childbirth, we employ the probability effect probit model since the endogeneity was not detected between housing tenure and birth rate. We document the differential effects of housing tenure on childbirth in that the first childbirth rate is higher for households without housing tenures. The negative effects on first childbirth could be attributed to the economic burden due to initial housing ownership, while housing tenure could eventually provide housing stability, leading to positive effects on more than one childbirth. Finally, we identify that households with childbirth over the last year show a 4.2%p and 3.9%p lower probabilities of housing tenure in the total sample and second childbirth sample, respectively. This suggests that the increased living cost due to childbirth could delay home ownership.
Using Herzberg's motive hygiene theory, this study also investigated the influence of motivation factors and hygiene factors on acceptance and resistance of mobile facial recognition payment services, and the influence of consumer innovation as a parameter on acceptance and resistance from motivation factors and hygiene factors. A survey was conducted on Chinese users who had experience using mobile payment services. IBM SPSS Statistics 26 and SmartPLS 3.0 were used for statistical analysis. As a result of the analysis, the motivating factors of mobile facial recognition payment services have a positive (+) impact on acceptance, and there were no significant results on resistance. In addition, hygiene factors have been shown to have negative (-) effects on acceptance and positive (+) effects on resistance. Consumer innovation, which is a parameter in relation to motivation factors and acceptance and resistance, had a partial mediation effect, and a partial mediation effect was also seen in the relationship between hygiene factors and resistance, but no mediation effect was found in the relationship between hygiene factors and acceptance. The motivating factors found through research results such as rapidity, ubiquity, perceived usability, perceived ease of use, privacy concerns, security, status quo inertia, use barriers, and loss avoidance, which are factors of non-contact and hygiene, can be used as basic data for activating mobile facial recognition payment services.
This study aims to examine the extent of lifestyle behavior changes, perceived restrictions in daily life, and their relationship during the COVID-19 pandemic. Using the 2020 Community Health Survey data, this study calculated perceived restrictions in daily life among adults in Korea during the pandemic by sociodemographic characteristics and lifestyle behavior category (physical activity, sleeping duration, drinking, smoking, social contact, public transport use, food delivery, instant food consumption). The generalized linear model examined the relationship between behavior change and perceived restriction on daily life. A total of 227,808 respondents were analyzed. 56.70% of the population perceived their daily lives restricted by 50% and more during the pandemic. The majority of the population decreased physical activity, social contact, and public transport use (52.71%, 89.70%, and 63.74%, respectively). Individuals who decreased physical activity, sleep duration, and social contact frequency, and those who increased drinking frequency, food delivery, and instant food consumption perceived greater restrictions in daily life than those who did not change respective behaviors (p<0.001). In conclusion, decreases in social contact and physical activity and increases in use of food delivery and instant food consumption were associated with greater perceived restrictions of daily life during the pandemic. Efforts to alleviate the negative impact of the pandemic on psychological well-being may need to involve attempts to improve healthy life behaviors.
In this study, daily data from January 2002 to June 2022 were used to investigate the relationship between risk-return relationship and market fear, uncertainty, stock market, and maritime freight index for the crude oil market. For this study, the time varying EGARCH-M model was applied to the risk-return relationship, and the wavelet consistency model was used to analyze the relationship between market fear, uncertainty, stock market, and maritime freight index. The analysis results of this study are as follows. First, according to the results of the time-varying risk-return relationship, the crude oil market was found to be related to high returns and high risks. Second, the results of correlation and Granger causality test, it was found that there was a weak correlation between the risk-return relationship and VIX, EPU, S&P500, and BDI. In addition, it was found that there was no two-way causal relationship in the risk-return relationship with EPU and S&P500, but VIX and BDI were found to affect the risk-return relationship. Third, looking at the results of wavelet coherence, it was found that the degree of the risk-return relationship and the relationship between VIX, EPU, S&P500, and BDI was time-varying. In particular, it was found that the relationship between each other was high before and after the crisis period (financial crisis, COVID-19). And it was found to be highly associated with organs. In addition, the risk-return relationship was found to have a positive relationship with VIX and EPU, and a negative relationship with S&P500 and BDI. Therefore, market participants should be well aware of economic environmental changes when making decisions.
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