• Journal of Chest Surgery
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• 제51권6호
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• pp.395-398
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• 2018

Neo-aortic insufficiency associated with root enlargement following an arterial switch operation is a serious late complication. To achieve successful surgical correction of this condition, multiple factors should be considered, including the individual patient's anatomy, the challenging nature of the redo procedure, and the patient's young age. However, limited publications have described the use of valve-sparing techniques for the treatment of neo-aortic insufficiency associated with root enlargement following an arterial switch operation. Herein, we report our recent experience of a valve-sparing aortic root procedure with ascending aorta and hemiarch replacement despite the presence of a discrepancy in leaflet size and nearby severe adhesions.

• 식품과학과 산업
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• 제50권3호
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• pp.51-59
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• 2017

Due to the nature of HMR food that is susceptible to contamination, its safety management is becoming more important. The relevant food types in food code corresponding to HMR foods are addressed, and the criteria for hygiene indicator bacteria and food poisoning bacteria, and storage and distribution standards according to the product type were presented. The government's safety management for HMR foods is basically carried out through the Food Sanitation Act. Those who intend to do HMR business must complete business registration or declaration, hygiene education, health examination of employees, and comply with legal obligations such as HACCP application. The government confirms compliance with legal requirements through hygiene inspection and monitoring inspection of products. However, the safety of HMR foods is not realized by the safety management system alone. A food safety culture should be established in which industry workers and consumers carry out actions to ensure food safety.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 1999년도 학술발표회 진행표 및 논문초록
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• pp.45-45
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• 1999

Cytochrome c (cyt c) binds to acidic membranes at low ionic strength. Replacement of Lys-72 or Lys-87 by Glu reduced the binding affinity of cyt c toward large unilamellar vesicles (LUV) in liquid crystalline phase. The differences were smaller for LUV in gel phase. A fraction of bound cyt c was non-electrostatically associated.(omitted)

• Asian-Australasian Journal of Animal Sciences
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• 제3권3호
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• pp.231-242
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• 1990

A study is reported which investigated the additive nature of digestible energy (DE) from dietary nutrients and to estimate the relative energy values of different energy-yielding nutrients in practical trout diets. A growth study was conducted over 12 weeks with 6 diets. Rainbow trout (Oncorhynchus mykiss) were fed diets once a day ad libitum. Digestible energy values determined and calculated had direct relationship indicating additive nature of such values for feed ingredients. Overall growth performance was best in a diet containing 33% digestible protein (DP) with a DP/DE ratio of 18.6. A reduction in digestible protein level with the same DP/DE rat io led to a significant decrease in growth and feed efficiency. The increase of 7% of lipid with concomitant decrease in protein resulted in the relative gain of 130% in growth and nutrient retention, suggesting that 1 g of lipid is equal to about 1.3 g of proteins in terms of net energetic value. Replacement of 10% of dietary lipid by carbohydrates led to a slight decrease in energy retention efficiency but to a great increase in lipid retention efficiency (130%) showing that dietary carbohydrates led to increased lipogenesis.

• 대한기계학회논문집A
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• 제38권11호
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• pp.1245-1256
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• 2014

피로균열 진전거동은 내재적, 외재적 요인에 의하여 시간 경과에 따라 많은 변동을 보인다. 감마과정 모델을 포함하여 연속적, 점진적 그리고 단조롭게 진전하는 피로균열 진전거동의 불확실성을 모사하기 위한 열화모델을 고찰하였다. Lu와 Meeker의 피로시험 자료에 감마과정 모델을 적용하여 시간에 따라 확률적으로 변동하는 피로균열 진전거동을 예측하였다. 피로균열 진전에 관한 상태저하와 수명을 시간에 따라 형상이 변화하는 확률분포 곡선으로 표현하였으며 비대칭도와의 관계로부터 기대수명으로 중위수의 적용이 적절함을 확인하였다. 최적 교체주기와 백분위 수명에 관한 고찰로 감마과정 모델이 예방정비을 위한 정책판단 기준으로 활용할 수 있음을 제시하였다.

• 한국지반환경공학회 논문집
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• 제13권3호
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• pp.53-58
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• 2012

일반적으로 연약지반인 점성토 지반이나 느슨한 사질토 지반을 개량하기 위하여 모래다짐말뚝(SCP)공법 또는 쇄석다짐말뚝(GCP)공법이 쓰여지고 있다. 하지만 모래다짐공법은 모래의 수급부족과 모래채취로 인한 환경파괴와 같은 문제점이 있으며, 쇄석다짐공법은 쇄석다짐재료의 클로깅으로 인하여 배수재의 투수계수가 저하되는 문제점이 있다. 최근, 모래와 공학적 성질이 유사한 화력발전소 부산물인 저회를 모래의 대체 재료로 활용하기 위한 연구가 이루어지고 있다. 본 연구에서는 저회혼합다짐말뚝에 대한 기초적 연구로써 조립재료 및 치환율에 따른 조립재료 혼합다짐말뚝의 거동특성을 수치해석적으로 규명하였다. 특히, 말뚝중심부로부터 거리에 따른 침하저감비(SRR)를 산정하였다. 연구 결과는 다음과 같았다. 조립재료에 따른 혼합다짐말뚝의 침하저감비 변화값은 유사한 형태를 보였으며 치환율에 따라 복합지반의 강성이 증대하여 침하저감비는 감소하는 형태를 보였다. 특히, 치환율 20~40%의 범위에서는 일반적으로 침하저감비의 증가가 큰 것으로 나타났고, 치환율 40% 이상에서는 증가치가 서서히 감소하는것으로 나타났다. 본 연구에서 적용한 연약지반과 유사한 지반에 혼합다짐말뚝 적용 시 경제성을 고려하였을 때, 30~40%의 치환율이 적절할 것으로 사료된다.

• 한국조경학회지
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• 제32권1호
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• pp.104-126
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• 2004

The recognition of the environment and its importance have generated various types of parks, such as the ecological put the environmental put and the natural academy. They are considered the connecting media for the creation of space as a new paradigm in design for the 21st century from the late 1990s, environmental designs in space planning have been created from various angles of Perspectives including restoration of the natural ecosystem and introduction of natural circulation systems. Based on the aye facts and through theoretical examination of environmental park models, this research (1) establishes the concept and the significance of environmental parte; and, based on this, classifies the types of industrial sublimity; (2) presents environmental designing principles and standards; and (3) presents the "Chung Ra pro-Environmental Park plan" based on these ideas. The following is the summary of research results: First, while existing city parks are human-oriented, interior-oriented, and shape-centered, an environmental park considers human and nature equally and gives great importance to the relationship between the internal and external of the subject. It is a mark of environmental education that considers the natural ecosystem. Therefore, the environmental park is the 21st Century′s type of an open park for creating new forms of nature, as well as for incorporating culture and values through education. In such an environmental system, nature, culture, and human beings pursue balance, harmony, and security through mutual recognition. Second, in a broad sense, the types of environmental park can be classified into Cultural Restoration, Ecological Conservation, and Environmental Replacement. Third, by selecting Chung na environmental park in Incheon, which is a filtration plant lot, as a research subject, I have presented alternative planning for environmental parte in which culture and nature coexist on the basis of environmental planning principles and standards.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 춘계 학술발표회
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• pp.595-598
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• 2010

Many economical and efficient methods such as sand drain method(SD), plastic board drain(PBD), sand compaction pile, vacuum consolidation method, etc., have been used for soft grounds. The case of sand compaction pile has an effect on accelerating consolidation and increasing bearing capacity by penetration at regular intervals under soft grounds for reducing the drainage path. But, this method has caused not only the nature damage by extracting the sands indiscreetly but also the economical problem for importing the sands because it needs so much sand to make the sand compaction pile. Thus, this study choosed the bottom ash which has similar engineering characteristics with sand. It was performed that clogging test and large direct shear test changing the bottom ash replacement ratio in soft ground for studying strength characteristics of soft ground using bottom ash compaction pile. As a result of the test, the internal friction angle was largely increased and the cohesion was decreased as the replacement ratio increased.

• Journal of mucopolysaccharidosis and rare diseases
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• 제4권1호
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• pp.21-25
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• 2018

Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.263-266
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• 1997

Three dimensional numerical model based on the finite element method(FEM) were developed to predict the mechanical behavior of hip implants. The purpose of this study is to investigate the stress distribution of two types of cementless total hip replacement femoral component -a straight stem and a curved stem, and to compare their effect on the stress shielding between two types by three dimensional finite element method. The authors analyzed von Mises stress in the cortex & stem and compared the stress between the straight and the curved stem. In comparison of stresses between two different design of femoral stem, there was 25% more decrease of stress in straight stem than curved stem in the medial cortex at proximal region. The straight stem had consistently much lower stresses than the curved stem throughout the whole medial cortex with maximum 70% reduction of stress. However, there was little change in stress between nature and 2 implanted femur throughout the lateral cortex. Stress of femoral stem was much higher in the straight stem than the curved stem up to 60%. The straight stem had more chance of stress shielding and a risk of fatigue fracture of the stem compared with the curved stem in noncement hip arthroplasty. In design of femoral stem still we have to consider to develop design to distribute more even stress on the proximal medial cortex.