• 제목/요약/키워드: Natural products

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Norsesquiterpene and Steroid Constituents of Humulus japonicus

  • Yu, Byung-Chul;Yang, Min-Cheol;Lee, Kyu-Ha;Kim, Ki-Hyun;Lee, Kang-Ro
    • Natural Product Sciences
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    • 제13권4호
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    • pp.332-336
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    • 2007

  • Five steroids and two norsesquiterpene glycosides were isolated from the methanol extract of H. japonicus. Their structures were determined by means of physio-chemical and spectral data to be friedelin (1), stigmast-5-en-3-${\beta}$-ol (${\beta}$-sitosterol) (2), 7-keto-${\beta}$-sitosterol (3), 6${\beta}$-hydroxy-4-stigmasten-3-one (4), 7${\alpha}$-hydroxy-${\beta}$-sitosterol (5), 3-hydroxy-4,4-dimethyl-4-butyrolactone (6), daucosterol (7), (6S, 9S)-roseoside (8), and (9S)-drummondol-9-O-${\beta}$-D-glucopyranoside (spinoside B) (9). The compounds 1, 3, 4, and 6 - 9 were first isolated from this plant source.

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Isoflavonoids of Belamcanda chinensis

  • Lee, Shin-Ock;Woo, Won-Sick;Woo, Eun-Hee;Kim, Ki-Soo
    • 생약학회지
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    • 제20권4호
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    • pp.219-222
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    • 1989

  • Tectorigenin, irigenin, their glucosides and 5,3'-dihydroxy-4',5'-dimethoxy-6,7-methylenedioxyisoflavone were isolated from the rhizomes of Belamcanda chinensis.

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Coumarins from Angelica gigas Roots having Rat Lens Aldose Reductase Activity

  • Lee, Sang-Hyun;Jung, Sang-Hoon;Lee, Yeon-Sil;Shin, Kuk-Hyun
    • Biomolecules & Therapeutics
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    • 제10권2호
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    • pp.85-88
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    • 2002

  • Systematic fractionation of Angelica gigas roots led to the isolation of linear coumarins such as decursinol angelate, decursin and nodakenin. These compounds were tested for their effects on rat lens aldose reductase. Nodakenin was demonstrated to exhibit significant inhibition of rat lens aldose reductase activity with $IC_{50}$ value of $7.33\Mu\textrm{M}$.

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Platelet Anti-Aggregation of Paeony Root

  • Kang, Sam-Sik;Kim, Ju-Sun;Kim, Eun-Mi;Yun-Choi, Hye-Sook
    • 생약학회지
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    • 제22권4호
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    • pp.215-218
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    • 1991

  • Paeony root was extracted and fractionated for the identification of the platelet anti-aggregatory components. And gallic acid methylester was isolated as the major component from the active sub-fraction F302.

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