• Title/Summary/Keyword: Natural antioxidants

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The antioxidant and cytotoxic activities of Sonchus oleraceus L. extracts

  • Yin, Jie;Kwon, Gu-Joong;Wang, Myeong-Hyeon
    • Nutrition Research and Practice
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    • v.1 no.3
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    • pp.189-194
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    • 2007
  • This study investigated in vitro antioxidant activity of Sonchus oleraceus L. by extraction solvent, which were examined by reducing power, hydroxyl radical-scavenging activity(HRSA) and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assays. 70% MeOH extract had the greatest reducing power while EtOH extract had the greatest HRSA. The antioxidant activity of S. oleraceus extracts was concentration dependent and its $IC_{50}$ values ranged from 47.1 to $210.5\;{\mu}g/ml$ and $IC_{50}$ of 70% MeOH, boiling water and 70% EtOH extracts were 47.1, 52.7 and $56.5\;{\mu}g/ml$, respectively. 70% MeOH extract of S. oleraceus contained the greatest amount of both phenolic and flavonoid contents. The extracts tested had greater nitrite scavenging effects at lower pH conditions. The cytotoxic activity showed that EtOH extract had the best activity against the growth of stomach cancer cell. These results suggest that S. oleraceus extract could be used as a potential source of natural antioxidants.

Antioxidant Activity of the Seagrass Zostera japonica (애기거머리말의 항산화 활성)

  • Kwak, Myoung Kuk;Kim, Da Seul;Oh, Kwang-Suk;Seo, Youngwan
    • KSBB Journal
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    • v.29 no.4
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    • pp.271-277
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    • 2014
  • In this study, crude extract of the seagrass Zostera japonica, and its solvent-partitioned fractions were evaluated for their antioxidant activity. The crude extract was successively fractionated into n-hexane, 85% aqueous methanol (85% aq.MeOH), n-butanol (n-BuOH), and water fractions by liquid-liquid partition. These include DPPH radical scavenging, hydroxyl radical scavenging in HT-1080 cells, peroxynitrite scavenging, and protective effect on DNA damage caused by hydroxyl radicals generated. In all assays, except for DPPH radical, 85% aq.MeOH and n-BuOH fraction showed the strong antioxidant activity. These results suggest that Z. japonica may be used as a potential source of natural antioxidants for the development of cosmetic product or functional food in the future.

Isolation of Prenylated Isoflavonoids from Cudrania tricuspidata Fruits that Inhibit A2E Photooxidation

  • Uddin, Golam Mezbah;Lee, Hee-Ju;Jeon, Je-Seung;Chung, Dong-Hwa;Kim, Chul-Young
    • Natural Product Sciences
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    • v.17 no.3
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    • pp.206-211
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    • 2011
  • High-performance liquid chromatography coupled to an online $ABTS^+$-based assay (online HPLC-$ABTS^+$) system was used to determine the principal antioxidants in Cudrania tricuspidata fruits. Six prenylated isoflavonoids (1 - 6) were isolated from C. tricuspidata fruits according to the online HPLC-$ABTS^+$ system. The structures of isolated compounds, alpiniumisoflavone (1), 6,8-diprenylorobol (2), 6,8-diprenylgenistein (3), pomiferin (4), 4'-methylalpiniumisoflavone (5), and osajin (6) were identified by their retention time, UV spectra, ESI-MS, and NMR data. Among these compounds, 6,8-diprenylorobol (2) and pomiferin (4) reduced A2E photooxidation in a dose dependent manner.

Novel Antioxidants, Stc-l and Stc-2, from Stereum ostrea

  • Kim, Young-Hee;Yun, Bong-Sik;Kim, Jong-Pyong;Moon, Suk-Sik;Yoo, Ick-Dong
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1998.11a
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    • pp.131-131
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    • 1998
  • In the course of screening for new natural compounds having antioxidant activity from microbials, mushrooms as well as plants. We have isolated novel sesquiterpenoid and officinalic acid from methanolic extracts of Stereum ostrea. The dried fruit body( 450 g) of Stereum ostrea was extracted with methanol, then methanolic extract was partitioned between water and hexane, chloroform, and ethyl acetate, subsequently. The chloroform extract was subjected on silica gel, Sephadex LH-20 and RP-18 column chromatography, successively. And two compounds were isolated and identified as new triterpenoids and officinalic acid using $^1$H - NMR, $\^$13/C - NMR as well as Mass spectra.

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Antioxidative Activity of Phenolic Compounds in Roasted Safflower (Carthamus tinctorius L.) Seeds

  • Kang, Ga-Hwa;Chang, Eun-Ju;Park, Sang-Won
    • Preventive Nutrition and Food Science
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    • v.4 no.4
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    • pp.221-225
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    • 1999
  • Antioxidative compounds contained in roasted safflower seeds were investigated. Six phenolic compounds, N-feruloylserotonin, N-(p-coumaroyl) serotonin, matairesinol, 8'-hydroxyarctigenin, acacetin 7-Ο-β-D-glucoside(tilianine) and acacetin were isolated and identified from the extract of seeds. The inhibitory effects of six phenolic compounds on 1,1-dipheny1-2-picrylhydrazyl(DPPH) radical and lipid peroxidation induced by H₂O₂/FeSO₄in rat liver microsomes were determined. Two serotonins showed more potent DPPH radical scavenging activity, and a stronger inhibitory effect on the lipid peroxidation than that of α-tocopherol. In addition, acacetin and matairesinol also considerably inhibited lipid peroxidation, while 2-hydroxy-arctigenin and tilianine were inactive. These results suggest that phenolic compounds, including serotonins, lignans and flavonoids in the roasted safflower seeds can be used as potential dietary natural antioxidants.

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Application of Naturally Antioxidant for Inhibition of Brightness Reversion of Paper Made from High Yield Bagasse Pulp

  • El-Sakhawy Mohamed;El-Ghorab Ahmed;El-Gendy Ahmed;El-Sabour Mona A.;El-Sayed Essam S. A.
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.37 no.5 s.113
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    • pp.15-24
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    • 2005
  • Different types of antioxidants compounds were prepared economically from natural sources. Application of these compounds towards photo stabilization of high yield bagasse pulp has been investigated. It was found that potato peel antioxidant followed by clove volatile oil provides lower brightness reversion and better photo stabilization effect for paper made from high yield bagasse pulp after exposure to UV lights in comparison with butyl hydroxy anisol or chamomile volatile oil.

Antioxidant Activities of Different Parts of Synurus deltoids Nakai Extracts in Vitro

  • Jung, Mee-Jung;Heo, Seong-Il;Wang, Myeong-Hyeon
    • Food Science and Biotechnology
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    • v.17 no.6
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    • pp.1156-1159
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    • 2008
  • The antioxidant activity of hot water extracts of various parts, the leaf, stem, and root of Synurus deltoides was evaluated by various antioxidant assays, including total phenolic content, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, hydroxyl radical (${\cdot}OH$) scavenging, superoxide dismutase (SOD), and xanthine oxidase (XOI) activities. The various antioxidant activities were compared with the standard antioxidants such as L-ascorbic acid, $\alpha$-tocopherol, and butylated hydroxyanisole (BHA). Among the different plant parts, stem has been found to possess the highest activity in all tested model systems, the activity decreased in the order stems>roots>leaves. These results indicate that stem extract could be used as potential source of natural antioxidant.

In vitro free radical scavenging potential of acetone extract and sub-fractions of Albizia amara (Roxb.) Boiv. stem bark

  • Sowndhararajan, Kandhasamy;Kang, Sun-Chul
    • Current Research on Agriculture and Life Sciences
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    • v.30 no.2
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    • pp.110-114
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    • 2012
  • In the present study, acetone extract and sub-fractions of Albizia amara stem bark were evaluated for their free radical potential. The results showed that the crude extract and all the fractions exhibited antioxidant and free radical scavenging activities under different in vitro assays. Among the different fractions, the ethyl acetate fraction exhibited higher DPPH and ABTS radical scavenging activities than the standard quercetin. A. amara stem bark might be valuable source of natural antioxidants that could be used for medicinal and food applications.

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Antioxidative Constituents from the Woods of Liriodendron tulipifera

  • Lee, Yeon-Suk;Lee, Hak-Ju;Park, YoungKi;Park, Jae-In;Choi, Tae-Ho
    • Journal of the Korean Wood Science and Technology
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    • v.32 no.6
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    • pp.43-49
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    • 2004
  • Three flavonoids, quercetin, taxifolin, and kaempferol were isolated from the woods of Liriodendron tulipifera. Their structures were determined by spectral analysis. Based on 1, l-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity method, the antioxidative activities of three isolated compounds and their acetates were measured in order to search for natural antioxidants. The IC50 of quercetin (1), taxifolin (2), and kaempferol (3) were 3.6, 3.9, and 4.1 ㎍/㎖, respectively.

Ameliorative effects of propolis upon reproductive toxicity in males

  • Saleem Ali Banihani
    • Clinical and Experimental Reproductive Medicine
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    • v.50 no.1
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    • pp.12-18
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    • 2023
  • Propolis is a sticky natural product produced by honeybees. Research studies have discussed the effectiveness of propolis, directly or indirectly, for ameliorating reproductive toxicity in males; however, this research has not yet been reviewed. The current paper presents an integrative summary of all research studies in Scopus and PubMed that investigated the effects of propolis on semen quality, and hence on male fertility, in conditions of reproductive toxicity. The consensus indicates that propolis ameliorates reproductive toxicity and enhances semen quality in vivo in test animals. These effects may be attributable to the ability of propolis to reduce testicular oxidative damage, enhance testicular antioxidant defense mechanisms, increase nitric oxide production, reduce testicular apoptotic injury, and boost testosterone production. However, to generalize these effects in humans would require further research.