• Title/Summary/Keyword: Natural Standard

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The Comparative Analysis of the Titer of Seroconversion Rate Through the Natural Antibody and Antibody after Vaccination of Hepatitis A (A형 간염의 자연항체와 예방접종을 통한 항체 생성률의 역가 비교분석)

  • Kwon, Won Hyun;Kim, Kyung Hwa;Cho, Kyung A;Moon, Ki Choon;Kim, Jung In;Lee, In Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.2
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    • pp.95-100
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    • 2013
  • Purpose: Since 2008, hepatitis A patients was rapidly increasing. So, Most of the health checkup examinees were interested in whether hepatitis A antibody was a lot. thereby The number of tests was increasing. In recent years, Antibody test results in the range of cut-off values were increased. According to the cause analysis, most examinees had a hepatitis A vaccine. This study was conducted to classify hepatitis A antibody as natural antibody and antibody after vaccination and compared the titer for seroconversion rate based on cut-off values. Materials and Methods: For a month in August 2012, First, We surveyed 185 health examinees and classified 119 health examinees who had acquired natural antibody. Second, for employees who were inoculated against hepatitis at our hospital, We classified into 53 primary inoculators and 59 secondary inculators. when the standard of cut-off value was 1, The seroconversion rate was compared the titer divided by 0.90-1.10 (${\pm}$), 0.60-0,89 (1+), 0.30-0.59 (2+), 0.01-0.29 (3+) and we compared the titer for seroconversion rate by each manufacturer after vaccination. Results: When the standard of cut-off value was 1, the titer of 119 health examinees who had acquired natural antibody was 0.90-1.10 (${\pm}$): 0%, 0.60-0.89 (1+): 0%, 0.30-0.59 (2+): 4.2%, 0.01-0.29 (3+): 96% and the titer of <0.60 ($${\geq_-}2+$$) was 100%. The titer of 53 primary inoculators was 0.90-1.10 (${\pm}:59.1%$), 0.60-0.89 (1+): 18.1%, 0.30-0.59 (2+): 18.1%, 0.01-0.29 (3+): 4.6% and the seroconversion rate was 45.3%. The titer of $${\geq_-}0.60$$ ($${\leq_-}1+$$) was 77.3%. The titer of 59 secondary inoculators was 0.90-1.10 (${\pm}:1.9%$), 0.60-0.89 (1+): 15.4%, 0.30-0.59 (2+): 36.54%, 0.01-0.29 (3+): 46.2% and the seroconversion rate was 88.1%. The titer of <0.60 ($${\geq_-}2+$$) was 82.7%. When we compared the titer for seroconversion rate by each manufacturer after vaccination, the seroconversion rate of 53 primary inoculators was BNIBT: 20.8% (${\pm}:24.5%$), GB: 15.7% (${\pm}:7.8%$), RIAKEY: 94.3% (${\pm}:3.8%$), ROCHE: 83% (${\pm}:0%$), ABBOTT: 73.1% (${\pm}:5.8%$) and the seroconversion rate of 59 secondary inoculators was BNIBT : 86.4% (${\pm}:1.7%$), GB: 88.5% (${\pm}:1.9%$), RIAKEY: 100% (${\pm}:0%$), ROCHE: 98.3% (${\pm}:0%$), ABBOTT: 98.2% (${\pm}:0%$). Conclusion: The study show that the titer of natural immune antibodies is higher than the titer of vaccination and the titer of secondary inoculation is mainly higher than the titer of primary inoculation. Consequently, if we know the titer of hepatitis A antibodies, it will help to give resullt reports. And then, when we compared the titer and the seroconversion rate by each manufacturer, There was a very distinct difference. As the test subjects inoculate against hepatitis A (HAV), it is considered BNIBT, GB will occur false negative rate and RIAKEY, ROCHE, ABOTT will occur false positive rate.

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INVESTIGATION OF EMISSION RATES OF AMMONIA, NITROUS OXIDE AND OTHER EXHAUST COMPOUNDS FROM ALTERNATIVE- FUEL VEHICLES USING A CHASSIS DYNAMOMETER

  • Huai, T.;Durbin, T.-D.;Rhee, S.-H.;Norbeck, J.-M.
    • International Journal of Automotive Technology
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    • v.4 no.1
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    • pp.9-19
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    • 2003
  • Exhaust emissions were characterized for a fleet of 10 alternative-fuel vehicles (AFVx) including 5 compressed natural gas (CNG) vehicles. 3 liquefied petroleum gas (LPG) vehicles and 2 85% methanol/15% California Phase 2 gasoline (M85) vehicles. In addition to the standard regulated emissions and detailed speciation of organic gas compounds, Fourier Transform Infrared Spectroscopy (FTIR) was used to measure ammonia (NH$_3$) and nitrous oxide ($N_2$O) emissions. NH$_3$, emissions averaged 0.124 g/mi for the vehicle fleet with a range from <0.004 to 0.540 g/mi. $N_2$O emissions averaged 0.022 g/mi over the vehicle fleet with range from <0.002 to 0.077 g/mi. Modal emissions showed that both NH$_3$, and $N_2$O emissions began during catalyst light-off and continued as the catalyst reached its operating temperature. $N_2$O emissions primarily were formed during the initial stages of catalyst light-off. Detailed speciation measurements showed that the principal component of the fuel was also the primary organic gas species found in the exhaust. In particular, methane, propane and methanol composed on average 93%, 79%, and 75% of the organic gas emissions, respectively, for the CNG, LPG. and M85 vehicles.

A Case of Typhlitis Developed after Chemotherapy with Irinotecan and Cisplatin in a Patient with Small Cell Lung Carcinoma

  • Ji, Eun Hye;Kim, Young Min;Kim, Soo Jeong;Yeom, Soo Jeong;Ha, Sung Eun;Kang, Hyeon Hui;Kang, Ji Young;Lee, Sang Haak;Moon, Hwa Sik
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.5
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    • pp.288-291
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    • 2012
  • Typhlitis is a necrotizing colitis that usually occurs in neutropenic patients and develops most often in patients with hematologic malignancies such as leukemia and lymphoma. Typhlitis may proceed to bowel perforation, peritonitis and sepsis, which requires immediate treatment. Irinotecan is a semisynthetic analogue of the natural alkaloid camptothecin which prevents DNA from unwinding by inhibition of topoisomerase I. It is mainly used in colon cancer and small cell lung carcinoma (SCLC), of which the most common adverse effects are gastrointestinal toxicities. To the best of our knowledge, no case of typhlitis after chemotherapy with a standard dose of irinotecan in a solid tumor has been reported in the literature. We, herein, report the first case of typhlitis developed after chemotherapy combining irinotecan and cisplatin in a patient with SCLC.

Reliability and Validity of the Postural Balance Application Program Using the Movement Accelerometer Principles in Healthy Young Adults

  • Park, Seong-Doo;Kim, Ji-Seon;Kim, Suhn-Yeop
    • Physical Therapy Korea
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    • v.20 no.2
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    • pp.52-59
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    • 2013
  • The purpose of this study was to determine the reliability and validity of the postural balance program which uses the movement accelerating field principles of posture balance training and evaluation equipment and smartphone movement accelerometer program (SMAP) in healthy young adults. A total of 34 people were appointed as the subject among the healthy young adults. By using Biodex stability system (BSS) and SMAP on the subject, the posture balance capability was evaluated. For the test-retest reliability, SMAP showed the intra-class correlation (ICC: .62~.91) and standard error measurement (SEM: .01~.08). BSS showed the moderate to high reliability of ICC (.88~.93) and SEM (.02~.20). In the reliability of inter-rater, ICC (.59~.73) as to SMAP, showed the reliability of moderate in eyes open stability all (EOSA), eyes open stability anterior posterior (EOSAP), eyes open stability medial lateral (EOSML) and eyes open dinamic all (EODA), eyes open danamic anterior posterior (EODAP), and eyes open danamic medial lateral (EODML). However, ICC showed reliability which was as low as .59 less than in other movements. In addition, BSS showed the reliability of high as ICC (.70~.75). It showed reliability which was as low as ICC (.59 less than) in other movements. In correlation to the balance by attitudes between SMAP and BSS, EOSML (r=.62), EODA (r=.75), EODML (r=.72), ECDAP (r=.64), and ECDML (r=.69) shown differ significantly (p<.05). However, the correlation noted in other movements did not differ significantly. Therefore, SMAP and BSS can be usefully used in the posture balance assessment of the static and dynamic condition with eyes opened and closed.

Pathotype of Tobamovirus Isolates from Commercial Red Pepper Seeds (시판 고추 종자에서 분리한 Tobamovirus의 병원형)

  • Han, Jung-Heon;Lee, Cheol-Ho;La, Yong-Joon
    • Horticultural Science & Technology
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    • v.19 no.4
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    • pp.530-534
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    • 2001
  • A total of 23 isolates were obtained from seeds of 30 pepper cultivars by single lesion isolation on Nicotiana glutinosa. The isolates were tested for pathotype determination using standard pepper differentials. Two pathotypes of Tobamoviruses, namely P0 and P1.2 were detected from the pepper seeds, of which pathotype P1.2 was predominant. Pathotypes P1 and P1.2.3 were unable to detect in this study. All pepper cultivars except one showed resistance to two pathotypes, P0 and P1, but not to pathotype P1.2. These results could be useful for breeding Tobamovirus-resistant pepper and producing virus-free seed stock.

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5-Fluorouracil and Interleukin-2 Immunochemotherapy Enhances Immunogenicity of Non-Small Cell Lung Cancer A549 Cells through Upregulation of NKG2D Ligands

  • Zhao, Lei;Wang, Wen-Jia;Zhang, Jin-Nan;Zhang, Xing-Yi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.4039-4044
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    • 2014
  • Background: The aim of this study was to investigate the anti-cancer effects and mechanisms of immunochemotherapy of 5-fluorouracil (5-FU) and interleukin-2 (IL-2) on non-small cell lung cancer (NSCLC) A549 cells. Materials and Methods: In order to detect whether 5-FU+IL-2 could effectively inhibit tumor growth in vivo, we established an A549-bearing nude mouse model. The cytotoxicity of natural killer (NK) cells was evaluated using a standard chromium release assay. To evaluate the relevance of NK cells in 5-FU+IL-2-mediated tumor inhibitory effects, we depleted NK cells in A549-bearing mice by injecting anti-asialo-GM-1 antibodies. Effects of 5-FU+IL-2 on the expression and promoter activity of NKG2D ligands (MICA/MICB) in A549 cells in vitro were also assessed. Results: In A549-bearing nude mice, combination therapy significantly inhibited tumor growth in comparison with monotherapy with 5-FU or IL-2 and enhanced the recognition and lysis of tumor cells by NK cells. Further study of mechanisms showed that NK cells played a vital role in the anticancer immune response of 5-FU+IL-2 immunochemotherapy. In addition, the combination therapy synergistically stimulated the expression and promoter activity of MICA/MICB. Conclusions: 5-FU and IL-2 immunochemotherapy significantly inhibited tumor growth and activated NK cytotoxicity in vivo, and these effects were partly impaired after depleting NK cells in tumor-bearing mice. Combination treatment of 5-FU and IL-2 upregulated the expression and the promoter activity of MICA/MICB in A549 cells, which enhanced the recognition of A549 cells by NK cells. All of the data indicated that immunochemotherapy of 5-FU and IL-2 may provide a new treatment option for patients with lung cancer.

A Study of Sexual Attitudes in University Students - Q-methodological approach- (대학생들의 성의식에 대한 태도 유형 - Q-방법론적 접근 -)

  • Kweon, Hyun Joo;Chung, Hae Kyung;Ryu, Eun Jung;Chung, Yeon Kang
    • Journal of the Korean Society of School Health
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    • v.11 no.2
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    • pp.229-241
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    • 1998
  • Because sexual awareness is changing, I have tried to classify university students' attitudes toward sex. This study examined male and female university students and used a Q-method to measure these attitudes. Out of a total of 202, 33 statements were abstracted, and a P-sample of 1-7 parties consisting of 26 persons were studied. I Q-sorted the statements with a standard of 9 points for normal distribution and analyzed the data by means of a Principal Component Analysis with a Quan PC Program. According to the result of this research, university students' attitudes toward sex are divided into three types. Type 1 are called open-minded open: They may have a surgical abortion in case of an unexpected pregnancy and sexual intercourse occurs when a man and woman feel love for each other. They don't see sexual intercourse as a means reproduction nor virginal purity as unconditional. It is remarkable that these students regard sexual intercourse as a natural thing and sex as a basic desire of human beings. In short, they show an open-minded attitude toward sex. Type 2 are supporters of virginal purity; They regard virginal purity with great importance. They insist that both man and woman should be chaste but that sexual intercourse before marriage is unfavorable only to the woman. They do not believe in sexual intercourse without love and emphasize purity in sex education. Differen from type 1, they are very negative about surgical abortion. Type 3 experss love through sex. They belive that sexual intercourse makes a couple happy and a way to express their affection for each other. In other words, the relationship between man and woman is improved through sexual intercourse. They do not think of sexual intercourse in terms of childbirth.

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A Classification of Ecotourism Storytelling Types for Standardization of Ecotourism Information (생태관광 정보 표준화를 위한 생태관광 스토리텔링 유형분류)

  • Lee, Seung-Ju;Lee, Hyun-Sook;Seo, Jong-Cheol
    • Journal of the Korean association of regional geographers
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    • v.18 no.1
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    • pp.1-16
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    • 2012
  • As the tourists of ecotourism are increasing, the supply for detailed information on tourist attraction is also significantly increasing. As a result of survey given to tourists, it showed that they are more interested in natural ecological resources rather than history or culture among resources of ecotourism and pointed out that more information on the region needs to be supplemented. In order to provide accurate, detailed and standardized information to tourists, ecotourism resources were categorized as experience type from the position of consumer and ecological resource type. And the category of experience is again divided into 4 types - nature, education, communication and adventure. Moreover, after developing the web-based homepage for it, the research proposed the cases of Tae-an area and Ulleungdo Island. If the problems from test operation are supplemented, it is expected to suggest the standard of mobile based digital storytelling technology in the field of ecotourism.

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A Study on the Design Elements and Impact Factor for Regional Differentiation of Public Design (공공디자인의 지역적 차별성을 위한 디자인 요소 및 영향인자 연구)

  • Kim, Eun-Joo;Seo, Ji-Eun
    • Korean Institute of Interior Design Journal
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    • v.21 no.1
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    • pp.280-288
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    • 2012
  • The purpose of this study is to deduct influence factors by analyzing preferences for public design that can increase user satisfaction through differentiated identity of regions. The study methods are as follows. First, consider a concept and semantic change of public design through the relevant literatures and precedent studies and then understand application status of domestic and overseas public design. Second, extract design elements for regional differentiation through precedent studies and reclassify regional resources that have an effect. Third, understand the necessity level of public design for regional differentiation by targeting experts and research the extracted design element and the degree of reflection about regionality. Lastly, understand a correlation between design elements and influence factors about territorial regionality of public design based on the researched contents, and analyze the degree of reflection between each other. As a result of this study, a plan that used 'material' and 'color' had high preference on the aspect of design elements and this is an important element that can show regional differentiation of regions. public design of showing regional differentiation. Thus, it is considered that various methods of using 'material' and 'color' must be planned. 'Public space' among design territories was most effective, and the following was 'public facility'. In particular, 'public space' has high preference of using 'natural resources' and 'industrial resources', and therefore an effect of a plan that uses these is judged to be positive. This study can use these results as basic data that suggested the standard for utilization of regional factors for regional differentiation of public design.

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Behavioral Characteristics Investigation of Rack Structure Depending on Forklift Impact Scenarios and Storage Distributions (지게차 충돌 위치 및 보관물류 분포에 따른 선반구조물의 거동특성분석)

  • Ok, Seung-Yong;Kwon, Oh-Yong;Paik, Shin Won
    • Journal of the Korean Society of Safety
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    • v.28 no.6
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    • pp.49-56
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    • 2013
  • The statistics of recent accidents in warehouses show that a heavy toll of lives were produced by various accidents, e.g. collision, overturn, fall, slip, exposure to harmful substances or environments, etc. Of significant concern amongst them is the collision, especially the collision between forklift and storage rack structure. Accordingly, this study focuses on behavioral characteristics of rack structure subjected to dynamic impact loading of a forklift. For this purpose, time-domain response analysis has been performed on a standard 2-bay six-story rack structure consisting of columns, beams and bracing members with perforated open section. In order to investigate the most critical scenario, the impact loads are applied in both down-aisle and cross-aisle directions, and the impact locations are also varied along the shelves of the palettes. In order to deal with storage distributions, three types of rack structures are further taken into account: original empty rack structure with no storage, half-loaded rack structure and fully-loaded rack structure. The numerical simulation results demonstrate that the dynamic characteristics of the rack structure are significantly dependent on the distribution of the storage goods and its natural period varies from 0.24sec to 1.06sec, approximately 4.4 times. Further, the parametric studies show that the forklift impact is most critical to the safety of the rack structure when it collides either at the base or at the top of the rack structure.