• Tuberculosis and Respiratory Diseases
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• 제75권5호
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• pp.214-217
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• 2013

Treatment of lung cancer in patients with idiopathic pulmonary fibrosis (IPF) is difficult because the mortality rate after surgery or chemotherapy is high for these patients. Spontaneous regression of cancer is rare, especially in lung cancer. A 62-year-old man, previously diagnosed with IPF, presented with stage IIIC (T2N3M0) non-small cell lung cancer. About 4 months later, spontaneous regression of the primary tumor was observed without treatment. To the best of our knowledge, this is the first report of spontaneous regression of lung cancer in a patient with IPF.

• 대한물리의학회지
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• 제5권2호
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• pp.165-172
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• 2010

Purpose : The purpose of this study was to investigate curriculums of physical therapy education. Methods : We identified the curriculums of physical therapy education by internet. Results : In Korea, education on physical therapy started as a two-year program in 1963, and recently reorganized as three or four years programs. Currently some ten schools offer physical therapy programs for master's and doctor's degrees. The member countries of the World Confederation for Physical Therapy (WCPT) provide approximately ten types of education programs that take two to six years. In Korea, the same programs have three or four years of education periods. The American Physical Therapist Association (APTA) launched on the doctor of physical therapy (DPT) course in the late 1990s, encouraging physical therapists to acquire a doctorate degree. In addition, the U.S. Vision 2020 envisions that all physical therapists acquire DPT by the year 2020. As the medical field becomes more professional and specialized, physical therapists are expected to supplement and even replace works of doctors, instead of merely assisting them. It is necessary to reinforce education programs and improve related school systems to enhance status of physical therapist in accordance with the changing social needs and to provide quality service to patients. Conclusion : We suggest to change the curriculum of Korea. It is more accurately reflected the scope, depth, breadth, and rigor of the high-quality education preparation needed for current and future practice.

• Journal of Korean Medical Science
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• 제33권44호
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• pp.273.1-273.15
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• 2018

Background: Sparganosis is a larval cestodiasis caused by the plerocercoid of Spirometra spp. Since the first description of human sparganosis in 1924, several hundred cases have been reported in Korea. However, systematic approaches for literature surveys of Korean sparganosis have seldom appeared. Methods: We searched publicly available databases such as PubMed, Research Information Sharing Service, and Korea Medical Citation Index with relevant Medical Subject Headings. Results: At least 438 Korean sparganosis cases have been described from 1924 to 2015. Preoperative diagnosis has been significantly increased since the 1980s due to popularization of serological and imaging diagnostics. Cases were largely detected from fifth decades in general, but cerebral sparganosis was detected in relatively young age groups (third and fourth decades). Sparganosis was prevalent in men (75.9%). Consumption of frog/snake and drinking unfiltered water were found in 63.4% and 16.9% of patients, respectively. Most frequently affected sites were subcutaneous tissues (49.9%), followed by the central nervous system (36.2%). Involvements of visceral organs (7.6%), ocular regions (3.6%), and muscles (2.7%) were noticed. In women, breast sparganosis constituted a large proportion (34.2%). Sparganosis associated with immunocompromised patients has recently been reported. Conclusion: Sparganosis has been continuously reported in Korea during the past 90 years, although its incidence has decreased during the last 20 years. The disease is mostly characterized by subcutaneous nodule, but infection of the worm in vital organs often results in serious illness. Continuous awareness is warranted to monitor sparganosis occurrence and associated clinical consequences.

• 한국컴퓨터정보학회논문지
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• 제24권10호
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• pp.215-223
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• 2019

음주운전은 책임감과 판단력의 부족으로 인하여 사고를 일으키기 쉽다. 한국은 우발적인 음주사고에 대해 실형을 추구하고 있다. 음주 운전자에 대한 집행유예는 전체의 70% 이상을 설명하고 있다. 그러나 보호관찰기간 중에 보호관찰소에 왔던 사람들은 비자발적이었고, 변화에 대한 동기유발이 거의 없었으며, 그들에게 제공된 대규모의 집단적인 단기교육은 재발방지에 한계가 있었다. 소규모의 그룹과 장기교육에 추가하여 우리는 3개월 내에 음주습관의 변화를 살펴보기 위해 집중적인 단기 개입을 시도하였다. 결국, 음주통제의 효과성은 미래 음주운전자들에게 제공될 프로그램을 향상시키는데 있어서 차이를 만들면서 나타날 것이다. 음주운전은 교통사고 원인의 많은 부분을 설명하고 있으며, 그것은 세계의 많은 나라들처럼 음주운전을 막고 처벌하기 위해 노력해야 함을 의미한다.

• 대한두경부종양학회지
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• 제35권1호
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• pp.13-20
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• 2019

Background/Objectives: Despite multiple approaches of treatments for salivary duct carcinoma, there has been a need for more successful treatment methods because of its poor prognosis. Treatment options like immunotherapy using new technologies have been attempted. Based on recent study results indicating that targeting programmed death receptors are effective in treating various cancers, this study aimed to identify the frequency of PD-L1 expression and its impact on survival rate in salivary duct carcinoma. Materials & Methods: We studied 33 patients with salivary gland cancer who were available for histologic specimens. We examined the expression of PD-L1 in the tissues and analyzed the association with the survival rate and the association with various clinical parameters. Results: According to this study and review of similar studies, we discovered that the expression of PD-L1 in salivary duct carcinoma was lower than other types of cancers. The impact of PD-L1 on survival rate also showed inconsistency in salivary duct carcinoma. Conclusion: Immunotherapy by PD-1/PD-L1 checkpoint blockade in salivary duct carcinoma needs further evaluation for clinical application.

• 디지털융복합연구
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• 제19권12호
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• pp.359-367
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• 2021

본 연구의 목적은 텍스트 마이닝 및 CONCOR 분석을 활용해 국내 환자안전문화 연구주제를 분석하는 것이다. 연구방법은 자료수집, 데이터 전처리, 텍스트 마이닝과 사회연결망 분석, CONCOR 분석 단계로 진행하였으며, 2021년 9월1일 기준으로 '환자안전문화'의 주제어를 검색하여 중복된 논문과 본 연구 목적에 부합되지 않는 논문을 제외한 총 136편을 분석하였다. 자료 분석은 텍스톰(Textom)과 UCINET 프로그램을 이용하였다. 본 연구의 결과 환자안전문화 관련 연구의 TF(빈도)는 환자안전(patient safety), TF-IDF(문서상의 중요도)는 간호(nursing) 가 가장 높게 나타났다. CONCOR 분석결과 환자안전문화를 구성하는 지식 및 태도, 커뮤니케이션, 의료서비스, 팀, 작업환경, 구조, 조직 및 경영의 총 7개의 클러스터가 도출되었다. 추후 환자안전문화 구축과 환자결과와의 연관성에 대한 연구가 진행되어야 할 필요가 있다.

• 한국가스학회지
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• 제25권3호
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• pp.9-15
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• 2021

본 논문에서는 산업현장 화학물질 인체 접촉 증상 기반 지식베이스 구축 및 화학물질 추정 시스템 설계에 대한 연구이다. 미국NIH에서 제공하는 WISER 프로그램의 499개의 화학물질 접촉 증상 정보로 활용하였다. 지식베이스 구축을 위해 AllegroGraph 7.0.1 프로그램을 이용하였으며 입력된 Chemical structure로 Triple 값인 Cas No., Synonyms, Symptom, SMILES, InChl, Formula를 사용 하였다. 또한 작업자의 증상을 안내하는 방법은 AI 스피커를 활용한 방식이 가능하며 지식베이스 구축 결과 암모니아(CAS No: 7664-41-7)를 기준으로 39개의 증상이 WISER 프로그램과 동일함을 확인 하였다. 이를 통해 화학물질 추정 시스템의 증상 추출 과정에 지식베이스 구축이 가능하였다.

• Annals of Rehabilitation Medicine
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• 제42권6호
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• pp.833-837
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• 2018

Objective To investigate and demonstrate persistent increase of peak cough flow after mechanical in-exsufflator application, in patients with neuromuscular diseases and pneumonia. Methods A mechanical in-exsufflator was applied with patients in an upright or semi-upright sitting position (pressure setting, +40 and $-40cmH_2O$; in-exsufflation times, 2-3 and 1-2 seconds, respectively). Patients underwent five cycles, with 20-30 second intervals to prevent hyperventilation. Peak cough flow without and with assistive maneuvers, was evaluated before, and 15 and 45 minutes after mechanical in-exsufflator application. Results Peak cough flow was 92.6 L/min at baseline, and 100.4 and 100.7 L/min at 15 and 45 minutes after mechanical in-exsufflator application, respectively. Assisted peak cough flow at baseline, 15 minutes, and 45 minutes after mechanical in-exsufflator application was 170.7, 179.3, and 184.1 L/min, respectively. While peak cough flow and assisted peak cough flow increased significantly at 15 minutes after mechanical in-exsufflator application compared with baseline (p=0.030 and p=0.016), no statistical difference was observed between 15 and 45 minutes. Conclusion Increased peak cough flow after mechanical in-exsufflator application persists for at least 45 minutes.

• Annals of Coloproctology
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• 제34권6호
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• pp.299-305
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• 2018

Purpose: Inflammatory bowel disease (IBD) in Korea has been increasing in recent years, but accurate statistics about operations for IBD are lacking. The purpose of this study was to investigate the trends and current status of IBD surgeries in Korea. Methods: Using a national database from the Korea Health Insurance Review and Assessment Service, we analyzed data from patients who underwent surgery for Crohn disease and ulcerative colitis from January 2009 to October 2016. Results: The mean number of patients who underwent surgery for Crohn disease was 791.8 per year. Colorectal surgery, small bowel surgery, and anal surgery were performed fairly often (31.2%, 29.4%, 39.4%, respectively), and laparoscopic surgery continued to increase, recently exceeding 30%. About 50% of Crohn patients used biologics before and after surgery, and those patients also underwent a relatively high rate of anal surgeries (44.2%). The mean number of patients who underwent surgery for ulcerative colitis was 247.6 per year. Colorectal surgery accounted for more than half of all operations, and laparoscopic surgery has been increasing rapidly, having been performed in about 60% of patients in recent years. The incidence of colorectal cancer in patients with ulcerative colitis was very high and increased rapidly during the study period, reaching about 80%. Conclusion: The number of patients undergoing laparoscopic surgery for IBD in Korea has increased significantly. Biologics are actively used by patients with Crohn disease, with a high proportion of anal surgeries required. Many of the surgical indications for ulcerative colitis have shifted into colorectal cancer.

• 가정의학회지
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• 제39권6호
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• pp.325-332
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• 2018

Background: Hypertension is a major contributor to the global disease burden of cardiovascular and cerebrovascular disease. The aim of this study was to determine demographic and clinical factors associated with adherence to antihypertensive medication. Methods: From August 2012 to February 2015, we recruited 1,523 Korean patients with hypertension who visited family physicians. The study was conducted in 24 facilities located in urban and metropolitan areas. Of these facilities, two were primary care clinics and 22 were level 2 or 3 hospitals. Adherence was assessed using the pill count method; a cut-off value of 80% was used as the criterion for good adherence. Sociodemographic and lifestyle factors were compared between the adherent and nonadherent groups using the chi-square test for categorical variables and t-test for continuous variables. Binary logistic regression analysis was performed with medication adherence as the outcome variable. Results: Of the 1,523 patients, 1,245 (81.7%) showed good adherence to antihypertensive medication. In the multivariate logistic analysis, age ${\geq}65$ years, exercise, treatment in a metropolitan-located hospital, being on ${\geq}2$ classes of antihypertensive medication and concomitant medication for diabetes, and a family history of hypertension or cardiovascular diseases were associated with good adherence. Patients who had a habit of high salt intake were less adherent to medication. Conclusion: Multiple classes of antihypertensive medications, concomitant medication, and exercise were associated with good adherence to antihypertensive medication, and high salt intake was associated with poor adherence to antihypertensive medication. These factors should be considered to improve hypertension control.