• Journal of the Korean Child Neurology Society
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• v.26 no.4
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• pp.263-268
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• 2018

Purpose: Obesity and headache are two highly prevalent diseases both in childhood and adolescent. In this study, we assessed the prevalence of obesity in pediatric headaches patients in a single institution in Korea, and differences according to age, sex, headache type, frequency, intensity, and disability. Methods: We retrospectively reviewed the medical records of 340 subjects (6-18 years of age) who visited the Pediatric Headache Clinic of Bucheon St. Mary's Hospital during the period from January 2015 through March 2018. Data on age, sex, height and weight, as well as headache type, frequency, intensity and disability, were collected. Body Mass Index (BMI) percentile was calculated based on the 2017 Korean Children Adolescence Growth Chart. Results: 17.6% of the pediatric headache patients were obese. The prevalence of obesity in male patients was higher than females (Male 23.8% VS Female 11.6%, P=0.002). There were no significant differences in obesity rate according to age, headache type, frequency, intensity, and disability. Conclusion: The prevalence of obesity in the pediatric headache population was 17.6% which is higher than 10.1% in general population (Korea National Health and Nutrition Examination Survey, KNHANES, 2013).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.331-343
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• 2019

The purpose of this study is to observe the trends of heart age of Koreans by using the predictor of heart age of the Framingham Heart Study. The subjects were 20,012 adults aged 30~74 years who were enrolled in the Korean National Health and Nutrition Examination Survey from 2005~2013. They filled in the determinants data and they had no history of cardiovascular disease (CVD). The heart age was calculated using a non-laboratory based model of prediction. The difference of heart age and chronological age, and the rate of excessive heart age over 10 years were calculated. The annual trend, the difference according to gender, the age bracket and geographic region, the heart age were all evaluated. Data analysis performed using the SAS program (version 9.3). Complex designed analysis was done. The heart age showed differences according to gender, age bracket and geographic region. The heart age is a useful comprehensive indicator for predicting the CVD events in the near future. So, it could be used for the purposes of exercising caution and guidance on CVD for administering medical care. It is strongly recommended to use heart age as an indicator for customized medical management to focus efforts on relatively vulnerable subjects and their factors for CVD. Further study on Koreans' customized heart age is needed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.94-103
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• 2021

The purpose of this study was to identify the association between regular physical activity (PA) types and metabolic syndrome (MetS) in fertile women. Data were obtained from the seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-3, 2018). The sample consisted of 4,172 fertile women over 19 years of age. The data were analyzed using an independent t-test, χ2 test, and multiple logistic regression analysis for examining the association of regular PA and MetS. The prevalence of MetS in fertile women was 3.1% (n =128), and 1,972 fertile women (47.2%) practiced regular PA. Compared to the non-regular PA group, regular PA resulted in a significantly lower systolic blood pressure (p =.002), lower waist circumference (p <.001), lower fasting blood sugar (p =.007), and higher high-density lipoprotein cholesterol (p <.001). After controlling the confounding variables, multiple logistic regression showed that the regular PA group (odds ratio 0.59, 95% confidence interval 0.35-0.98, p =.040) and the regular muscle-strengthen PA group (odds ratio 0.34, 95% confidence interval 0.14-0.80, p =.013) were associated with a decreased risk of MetS. Therefore, regular PA, including muscle-strengthen PA should be considered to develop effective MetS intervention in fertile women.

• Journal of Plant Biotechnology
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• v.44 no.1
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• pp.76-81
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• 2017

Potentilla supina (Rosaceae) has traditionally been used to treat disorders of hemostasis, dysentery, malaria, bloody discharge and arthritis, and it has antinociceptive and anti-inflammatory properties. However, validity of the anti-inflammatory activity has not been scientifically investigated so far. Therefore, the aim of this study was to investigate the anti-inflammatory potential of P. supina using the ethanolic extract of P. supina and its sub-fractions. To evaluate the anti-inflammatory effects of P. supina, we examined the inflammatory mediators such as nitric oxide (NO), inducible nitric oxide synthase (iNOS) and prostaglandin $E_2$ ($PGE_2$) in RAW 264.7 cells. Our results indicated that ethyl acetate fraction significantly inhibited LPS-induced NO, iNOS and $PGE_2$ production in RAW 264.7 cells. This result showed that ethyl acetate fraction of P. supina is expected to be a good candidate for development into a source of anti-inflammatory agents.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.592-602
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• 2020

This study examined the contribution of the risk factors that cause cardiovascular disease in Koreans. The subjects were 20,012 adults aged 30~74 years who were enrolled from the 2005~2013 Korean National Health and Nutrition Examination Survey, had filled the risk factors data, and had no cardiovascular disease history. Data analysis was conducted using SAS 9.3, and a weighted composite sample design analysis was performed. The contribution was obtained by applying a squared semi-partial correlation. As a result, they were higher in the order of age (63.9%), smoking (17.3%), systolic blood pressure (7.9%), diabetes (6.9%), antihypertensive medication use (3.0%), and BMI (0.9%) in men. In women, the contributions were in the order of age (54.1%), systolic blood pressure (23.5%), diabetes (13.6%), antihypertensive medication use (5.1%), smoking (3.1%), and BMI (0.6%%). According to age bracket analysis, smoking (51.8~33.7%) was the biggest risk factor, followed in order by age (26.6%) in their 30s and systolic blood pressure (17.3~21.0%) in those older than 40 years in men. In women, the systolic blood pressure (56.2~40.5%) was the main contributor to the risk factors, followed by age (24.0%) in their 30s and diabetes (13.6~32.6%) in those older than 40 years. The contribution of the income level was similar. Therefore, to prevent cardiovascular disease, various programs that reflect the contributions of the risk factors should be developed. Moreover, it is recommended to use the results shown in this study as basic data.

• Journal of Korean Home Economics Education Association
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• v.34 no.1
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• pp.1-16
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• 2022

This study was performed to develop educational materials in the form of card news that can be easily accessed on mobile phones or the Internet for milk intake education of the elderly based on the scientific evidence and their needs. The themes included in the card news were selected based on the literature and focus group interviews with 10 elderly individuals (78.10±6.66 years old). For the selected themes, information that elderly users most want to know was selected for the purpose of effective communication, while reflecting the eating habits, lifestyle, living environment, and nutrition and health status of the elderly in Korea. The draft of the card news was reviewed by the researcher, consulted by experts, and surveyed with 50 elderly individuals (70.44±5.16 years old). Based on the results of the review, consultations, and the survey, a final draft of the card news consisting of 12 pages was completed. The card news of the present study is expected to be an effective educational material considering the high level of satisfaction (higher than 4 on the 5-point scales) indicated by the survey respondents. Therefore this card news is expected to help increase milk intake through friendly milk education for the elderly.

• Korean Journal of Environmental Agriculture
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• v.37 no.2
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• pp.79-86
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• 2018

BACKGROUND: Chinese cabbage biosynthesizes various phytochemicals including carotenoids and glucosinolates. Environmental stress has a major effect on the growth and yields of vegetables, and can significantly affect nutritionally important phytochemicals. Phytochemicals of plants are influenced by light, temperature, carbon dioxide, and growing conditions. The aim of this study was to investigate the effect of various light sources on carotenoid and glucosinolate contents in Chinese cabbage. METHODS AND RESULTS: [Experiment I] Set the control (field control, FC) on the ground. Using acrylic sunlight, experiments were set up transparency box (field transparency, FT), red box (field red, FR) and blue box (field blue, FB). [Experiment II] Set the control (chamber control, CC) in the greenhouse. Using plant growth chamber with artificial light, experiments were set up LED red (chamber red, CR), LED blue (chamber blue, CB), LED mixed red+blue (chamber red+blue, CRB) and fluorescent (chamber fluorescent, CF). After plant growth, Chinese cabbage was harvested at 110 days after sowing (DAS). The status of plants growth (leaf length, width, fresh weight etc.) was immediately investigated. Carotenoid and GSL contents were analyzed by HPLC. [Experiment I] Results documented that the ranges of total carotenoid contents were 25.39 ~ 58.80 mg/kg dry wt for lutein, 0.84~ 4.22 mg/kg dry wt for zeaxanthin, and 3.85~18.71 mg/kg dry wt for ${\beta}$-carotene. Lutein was the highest for the content and the largest for the variation as well. [Experiment II] Results documented that the ranges of total carotenoid contents were 24.66~137.96 for lutein, 2.51~20.65 for zeaxanthin, and 8.40~49.80 mg/kg dry wt for ${\beta}$-carotene. The total carotenoid contents of CR (156.62) and CB (115.90) were 1.6~2.3 times larger than the other treatments, and ${\beta}$-carotene content was about twice as high as that of the other treatments on the CR (38.74 mg/kg dry wt.). [Experiment I] Total GSL content was the highest in FT (19.76) that was higher 1.7 times than the lowest treatment ($11.39{\mu}mol/g\;dry\;wt$.). [Experiment II] The total content of GSL was highest in CRB (4.19) and lowest in CF ($2.88{\mu}mol/g\;dry\;wt$.). In the CRB, total GSL contents ($4.19{\mu}mol/g\;dry\;wt$.) was the highest. CONCLUSION: Total and individual carotenoid and GSL contents in Chinese cabbage show significant differences under different light sources. Red and blue lights contribute to significant carotenoids expression and antioxidant activity for nutrition and health benefits. These results concluded that the introduction of varying lights affected the synthesis of important nutrient compounds in Chinese cabbage. It is predicted that the application of good light source enhances the accumulation of functional compounds.

• Journal of Korean Home Economics Education Association
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• v.26 no.4
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• pp.21-34
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• 2014

This study examined the levels of recognition, knowledge, and intake behavior of foods containing caffeine and analyzed the factors affecting amount of caffeine intake to get basic materials for development of educational program for proper intake behavior of foods containing caffeine of high school students in Gyeongbuk region. Of 300 questionnaires that were distributed on December 27, 2013 to February 14, 2014, 255 responses were used for analysis. Frequency distributions, Cronbach's ${\alpha}$, t tests, one-way ANOVA, Pearson's correlation analysis, and regression analysis were conducted by SPSS Windows V.21.0. The mean of the level of concern about foods containing caffeine was 2.76/5.00 points; male and second and third grade students showed lower concern level than female and first grade students. The respondents answered that intake of foods containing caffeine had somewhat harmful effect on health, but it did not much help to refresh and increase concentration. The mean for the percentage of correct answers about knowledge of caffeine was 54.3. Small number of the respondents were advised to reduce intake of caffeine from school teachers or parents. The average of caffeine intake amount was 71.67mg/day; the average for male was 78.98mg/day, whereas for female 61.23mg/day. Almost thirteen percentage of the respondents took caffeine over RDA(Recommended Daily Allowance). According to the result of regression analysis for amount of caffeine intake, grade, BMI, concern about health, perception of whether foods containing caffeine help with refreshment and increase of concentration or not, and experiences of having advice from school teachers to decrease caffeine intake were significant. These results imply that it is necessary for high school students to educate how to take caffeine properly.

• Pediatric Infection and Vaccine
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• v.18 no.1
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• pp.40-47
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• 2011

Purpose : Norovirus infection, a common cause of community-acquired gastroenteritis, can also lead to severe illness in immunocompromised patients. We investigated clinical manifestations of norovirus infection in pediatric cancer patients. Methods : Stool specimens were collected from pediatric patients with gastrointestinal symptoms between November 2008 and September 2009 at Samsung Medical Center, Seoul, Korea. Norovirus infection was identified by reverse-transcription polymerase chain reaction (RT-PCR). A retrospective chart review was performed in pediatric cancer patients who were diagnosed with norovirus infection. Results : Ten patients were diagnosed with norovirus infection by RT-PCR in stool samples. The median age was 0.83 years (range 0.25-5.5 years) and the male to female ratio was 1.5:1 (6 males and 4 females). Underlying diseases were hematologic malignancies (4/10, 40%), neuroblastoma (4/10, 40%), and brain tumors (2/10, 20%). Three patients were infected before hematopoietic cell transplantation (HCT) and four patients after HCT. All patients had diarrhea (10/10, 100%), with a median frequency of diarrhea of 8.5 times/day (range 4-22 times/day). Median virus shedding duration was 72.5 days (range 19-299 days). Four patients with pneumatosis intestinalis were conservatively treated with bowel rest and total parenteral nutrition. One patient with severe diarrhea and bloody stool had concomitant chronic gut graft-versus-host disease (GVHD). Norovirus infection-related mortality was not observed. Conclusion : Norovirus infection can cause significant clinical manifestations with prolonged viral shedding in immunocompromised patients. Norovirus should be considered in pediatric cancer patients with severe gastrointestinal symptoms.

• Korean Journal of Food Science and Technology
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• v.17 no.1
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• pp.41-44
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• 1985

Dried black soybeans were soaked in water at the temperature range of $4^{\circ}C-100^{\circ}C$ and in the solution having various concentration of salt and sugar, in order to investigate their effects on water absorption characteristics. The hydration rate was determined by the method of weight gain during soaking. The times required to reach specified degrees of hydration were reduced logarithmically by increase of temperature, with showing a break point in their Z-values at $60^{\circ}C$. The temperature effect on hydrations of black soybeans was higher at the temperature below $60^{\circ}C$. Increase of NaCl or sucrose concentration in soaking solution reduced the hydration rate. The Z-values were changed at the concentration of 25% for sucrose and 16% for NaCl. The activation energy for hydration of 30%-50% was found to be 5.7-7.2Kcal/mole. The higher activation energy was required to reach higher degree of hydration.