• Journal of the military operations research society of Korea
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• v.29 no.2
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• pp.45-60
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• 2003

As we live in real If era, If become a mandatory component for nations and organizations to survive in severe competition. If is also thought of as strategic asset for effective business operations, yet there is no proved statement on the interoperability and system integration which causes serious problem in terms of requirement engineering among current systems. The National Defense Enterprise Architecture Framework is a strategic information asset base, which define the military operation activities for the mission, the information necessary for military operations, the technologies necessary for implementing new technology in response to changing operational needs. It is an integrated model or representation. Information Systems will be evolved by the National Defense Enterprise Architecture framework. The purpose of this framework is to present overall picture of national defense information system domain so that information systems are interoperated, integrated and information sharing is increased among affiliated organization of Defense Military.

• BMB Reports
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• v.56 no.9
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• pp.482-487
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• 2023

Hematopoiesis is regulated by crosstalk between long-term repopulating hematopoietic stem cells (LT-HSCs) and supporting niche cells in the bone marrow (BM). Here, we describe the role of KAI1, which is mainly expressed on LT-HSCs and rarely on other hematopoietic stem-progenitor cells (HSPCs), in niche-mediated LT-HSC maintenance. KAI1 activates TGF-β1/Smad3 signal in LT-HSCs, leading to the induction of CDK inhibitors and inhibition of the cell cycle. The KAI1-binding partner DARC is expressed on macrophages and stabilizes KAI1 on LT-HSCs, promoting their quiescence. Conversely, when DARC+ BM macrophages were absent, the level of surface KAI1 on LT-HSCs decreases, leading to cell-cycle entry, proliferation, and differentiation. Thus, KAI1 acts as a functional surface marker of LT-HSCs that regulates dormancy through interaction with DARC-expressing macrophages in the BM stem cell niche. Recently, we showed very special and rare macrophages expressing α-SMA+ COX2+ & DARC+ induce not only dormancy of LT-HSC through interaction of KAI1-DARC but also protect HSCs by down-regulating ROS through COX2 signaling. In the near future, the strategy to combine KAI1-positive LT-HSCs and α-SMA/Cox2/DARC triple-positive macrophages will improve the efficacy of stem cell transplantation after the ablative chemo-therapy for hematological disorders including leukemia.

• STI Policy Review
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• v.5 no.1
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• pp.34-56
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• 2014

This paper reviews the most central analytical and methodological issues that arise in developing national STI strategies. First, an outline of the relationship between national innovation systems and the strategic dimension is presented. The paper shows that science, technology and innovation strategy are often used in different forms and that there is no common understanding yet of the actual meaning and coverage of these strategies. The paper develops the terminology from a discussion of different approaches towards company innovation processes analyzing their evolution in different socioeconomic environments and the role and impact of science, technology and innovation policy on company innovation processes. Based on this conceptual understanding the paper defines national science, technology, innovation, and STI strategy and explains the basic terminology. From these definitions, the strategic dimension including the impact on the stakeholders is discussed. It is shown that a major success factor for STI strategy development is the involvement of stakeholders to vary and extend their use of their portfolio of instruments. Moreover it becomes evident that stakeholders follow their own interests which aren't necessarily in the interest of the national STI strategies. The analysis shows advantages and disadvantages as well as potentials and limitations of different approaches to develop STI strategies in their ability to describe the reality of innovation processes and to allow conclusions about the relationship between innovation policy and the innovation processes implemented by companies. It is shown that knowledge of these limitations is an important factor to consider in designing consistent and coherent national STI policy which aims at supporting innovation eventually. Finally the paper concludes that the STI policy mix concept needs a more systemic development approach which is integrated in the national STI strategy development and implementation.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.1
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• pp.1-14
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• 2023

To secure national future competitiveness, the Korean government announced the 『National Ultra-High Performance Computing (HPC) Innovation Strategy (2021.5.28.)』 and set three innovation strategy goals throughout establishing an innovation ecosystem. This study presented a heterogenous data-based strategic support framework that allowed to understand both the current status of domestic & foreign R&D areas and domestic industrial economy areas in terms of strategic fields related to ultra-high performance computing, and the empirical research was conducted in the life science and public health area. The HPC innovation ecosystem platform based on the connection of heterogeneous data (domestic R&D project-technology-industry-overseas R&D project) presented in this study provided useful and essential information that allowed establishing a specific action plan for the national HPC innovation strategy and contributing to vitalizing the innovation ecosystem. Since the evidence-based policy assumes that a more reasonable consensus is reached through a non-biased decision- making process among stakeholders, the proposed platform may contribute to enhancing policy momentum by increasing legitimacy and trust of planning of the national HPC strategy.

• 연구논문집
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• s.24
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• pp.141-149
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• 1994

Recently, IVHS technology attracted public attention according as national IVHS project was initiated by SOC. In advanced countries, specially in USA, Europe, and Japan. IVHS technology was already studied for over ten years as national strategic project. In this paper we describe the concept and development trend of AVCS which is a part of IVHS technology. The important contents in AVCS are automatic collision warning and avoidance system, automatic intelligent cruise control system, automatic vehicle platoon control system, automatic lateral control system, etc.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.21 no.1
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• pp.55-71
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• 2018

To improve the ecological function of urban areas, the guideline for applying the Biotope Area Ratio to the Environmental Impact Assessment (EIA) was developed in 2005 and modified in the July, 2017. This study investigates whether the guideline has been actually practiced in the real world by searching reports including 648 cases of the Strategic Environmental Impact Assessment (SEIA) and 471 cases of the EIA. The results show that the 38% of SEIA and the 43% of EIA include sections about Biotope Area Ratio, and the 15% of SEIA and the 25 % of EIA are satisfied the threshold of the Biotope Area Ratio suggested by the guideline. The statistical analysis results show that this low level of practice was not improved through the modification of the guideline in 2017. This is because the guideline is forcibleness, its explanation is unclear, and stockholders' understanding of it lacks. In addition, lack of tracking management on SEIA and EIA also contributes to the low level of practice of the guideline. To promote the practice, the efforts to legislate and publicize the guideline are required.

• IE interfaces
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• v.16 no.spc
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• pp.70-75
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• 2003

There have been dramatic technology changes in telecommunication sector during last two decades. New application services like the introduction of international mobile services, fiber optical home services and satellite personal services are expected to play a major role in the whole field of telecommunication services. In the users' viewpoint, the proper selection and the efficient application of the specific telecommunication service among the various alternatives at hand are recognized as principle means for ensuring the whole business competitiveness. Despite the definite need for the telecommunication service selection strategies, very few researches have been reported in this field. In this paper, attempts are made to identify the companies' decision factors considered in selecting the telecommunication services, to draw the strategic dimensions and categorize each company with respect to the identified dimensions, and to finally find the characteristics of each strategic group in selecting the telecommunication service.

• New & Renewable Energy
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• v.2 no.1 s.5
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• pp.21-25
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• 2006

Standards are increasing of importance for New & Renewable energy. The rapid growth of production is one reason for this but standards are equally important in ensuring the quality and reliability of installed New & Renewable energy systems, which have a propound impact on acceptance of the technology in the expanding marketplace. Korea government (Korea Agency for Technology and Standards, KAIST)make and implement a five year plans for promotion of international standardization of this field from 2004. KATS leads the technology innovations and eventually increases the international competitiveness. Strategic collaboration with other countries is also strengthened through Korea's participation in international standards and conformity assessment system such as IECEE(IEC system for conformity and certification of electrical equipment). One of the major goals of the Plan is to facilitate trade between Korea and its trading partners by emphasizing harmonization of its national conformity assessment system with international norms.

• Journal of Korea Technology Innovation Society
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• v.8 no.2
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• pp.650-676
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• 2005

It is important to identify the mid and long-term strategic technologies and evaluate technology level for the establishment of national R&D policy to upgrade technology level in Korea. This paper summarizes the result of technology level evaluation for 99 key technologies of 'National Technology Road Map', which consists of 5 visions, of Korea. The technology level, the technological gap between Korea and world-top country, the role of government to upgrade technology level, etc. were investigated by the survey (total 1,067 respondents) and the interview with experts related to key technologies. The average technology level of Korea was $65.1\%$ of that of world-top country and average technological gap was 5.8 years. The technology level of vision I 'Building an Information-Knowledge-Intelligence Society' was $71.6\%$ and highest among 5 visions. The highest technology level among 99 key technologies was $85.6\%$ for 'Digital Broadcasting Technology' and the lowest was $20\%$ for 'weather Control Technology'. The major reasons of technological gap were investigated as the lack of R&D personnel ($23.8\%$), the shortage of R&D funds ($17.8\%$), and the insufficiency of basic research ($15.4\%$), in sequence. The average technology level of USA was evaluated to highest in the world. It was presented that the technological power of China increased rapidly in the expert interview. The result of technology level evaluation would be primary information for various national S&T planning, such as S&T basic plan, S&T foresight, technology road map, etc.

• Journal of Korean Institute of Industrial Engineers
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• v.40 no.2
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• pp.172-183
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• 2014

This paper measures and compares the efficiency of national health technology R&D programs focused on translational research program increasing importance using data envelopment analysis (DEA). Three input variables and three output variables are selected for DEA. Inputs are funds, researchers, and project period and outputs are SCI (E) papers, applied and granted patents, and impact factor. This study uses a three-stage approach. In the first stage, output-based DEA model is applied to evaluate the efficiency of decision making unit (DMU). In the second stage, based on efficiency scores of target diseases high-efficiency group and low-efficiency group are classified. And then strategic portfolio matrix of translational research program is composed of four dimensions combining research types. Mann-Whitney U test is then run to compare average efficiency scores among four groups. In the final stage, Tobit regression model is used to estimate factors likely to influence the efficiency. The results are expected to provide policy implications for effectively establishing investment strategy and managing performance of R&D program.