• Title/Summary/Keyword: National R&D Report

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Comparison of Estradiol Results according to Manufacturer (제조회사에 따른 Estradiol 결과값의 비교)

  • Kim, Dae-Woon;Shin, Hee-Jung;You, Tae-Min;Noh, Gyeong-Woon;Kim, Hyun-Joo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.15 no.1
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    • pp.101-105
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    • 2011
  • Purpose: Estradiol in the menstrual cycle and ovulation induction as an important test of currently national nuclear medicine laboratory in the normal patients and patients with infertility tests are being performed. For the diagnosis of menopause is an important test with follicle stimulating hormone (FSH) and Luteinizing hormone (LH). Currently participating in external quality control of the nation's hospitals that is 54 percent of 37 hospitals, 20 hospitals have been using A's reagent. The kit's test results are highly different from other kit comes with the test results of specimens have been found. And for the phenomenon is to study the problem. Materials and Methods: Estraiol test were referred to our hospital which results of samples as more than 100pg/ml 75 specimens measured by radioimmunoassay(RIA) test with company A company B company C company D Kit, Chemiluminescent assay (CMIA) to examine and compare to the results from april to August in 2010. Results: Kit for each manufacturing company as measured by the results obtained using the average value of the correlation coefficient (R2) and A company 0.8906 B 0.9527 C 0.9547 and D company correlation coefficient of 0.873 showed a good correlation that measuring the results of A company high concentrations when Company B Company C Company D with CMIA test concentrations measured low results that the two cases were discovered specimens. Conclusion: Most of the test results of 75 samples came up with a similar trend, but two cases were reported in the patients very differently. A company result reported higher than 700 pg/ml, while the rest of other test results report was approximately 10 pg/ml. The common point of two samples more than 50 years patients are estimated to be diagnosed with cancer in postmenopausal patients receiving treatment and levels of FSH were found to be greater than 50 mIU/ml. Did not identify the exact cause. I suggest if you are using A company kit that need to again check when Estradiol result and follicle stimulating hormone results is higher.

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Case Studies of Indirect Coupled Behavior of Rock for Deep Geological Disposal of Spent Nuclear Fuel (사용후핵연료 심층처분을 위한 암석의 간접복합거동 연구사례)

  • Hoyoung, Jeong;Juhyi, Yim;Ki-Bok, Min;Sangki, Kwon;Seungbeom, Choi;Young Jin, Shin
    • Tunnel and Underground Space
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    • v.32 no.6
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    • pp.411-434
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    • 2022
  • In deep geological disposal concept for spent nuclear fuel, it is well-known that rock mass at near-field experiences the thermal-hydraulic-mechanical (THM) coupled behavior. The mechanical properties of rock changes during the coupled process, and it is important to consider the changes into the analysis of numerical simulation and in-situ tests for long-term stability evaluation of nuclear waste disposal repository. This report collected the previous studies on indirect coupled behaviors of rock. The effects of water saturation and temperature on some mechanical properties of rock was considered, while the change in hydraulic conductivity of rock due to stress was included in the indirect coupled behavior.

섭제골 지역의 산화지 및 비산화지의 군락구조 비교

  • Sim, Hak-Bo;Kim, Woen
    • The Korean Journal of Ecology
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    • v.16 no.4
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    • pp.429-438
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    • 1993
  • This is a report on the early vegetation and the secondary succession in the burned area of SeobJe-Go1 of $IIwasan-MY\v{o}n,\;Y\v{o}ngch\v{o}n-Gun,\;Ky\v{u}ngsangbuk-do$ Province. The forest fire occurred on April 8, 1982 and the pine forest and its floor vegetation were burned down. The investigation was done six times from August 20, 1982 to August 13, 1983. The results are summarized as follows: the floristic composition of burned areas $B_1,\;B_2$, and unburned areas $U_1,\;U_2$ were composed of 25, 23, 32, and 27 kinds of vascular plants. respectively. The biological spectra showed the $H-D_1-R_5-e$ type in both the burned and unburned areas. The species of Arundinella hirta, Miscanthus simnsis var. purpurascens and Cares hurnilis var. nana were dominant species in the burned area, while Pinus densiflorrr, Corex humilis var. nana and Rhododendron mucronulatum var. ciliafum were dominant species in the unburned area. Degree of succession of the unburned area was comparatively higher than that of the burned area. Species diversity index and evenness index of the burned area were similar to those of the unburned area. Indices of similarity in sampling sites showed that $B_1\;and\;B_2$ stands were the most similar. pH, total nitrogen, available phosphorus and exchangeable potassium of soil increased but organic matter and total organic carbon decreased after fire.

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Antibacterial Activity of Pharbitin, Isolated from the Seeds of Pharbitis nil, against Various Plant Pathogenic Bacteria

  • Nguyen, Hoa Thi;Yu, Nan Hee;Park, Ae Ran;Park, Hae Woong;Kim, In Seon;Kim, Jin-Cheol
    • Journal of Microbiology and Biotechnology
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    • v.27 no.10
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    • pp.1763-1772
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    • 2017
  • This study aimed to isolate and characterize antibacterial metabolites from Pharbitis nil seeds and investigate their antibacterial activity against various plant pathogenic bacteria. The methanol extract of P. nil seeds showed the strongest activity against Xanthomonas arboricola pv. pruni (Xap) with a minimum inhibition concentration (MIC) value of $250{\mu}g/ml$. Among the three solvent layers obtained from the methanol extract of P. nil seeds, only the butanol layer displayed the activity with an MIC value of $125{\mu}g/ml$ against Xap. An antibacterial fraction was obtained from P. nil seeds by repeated column chromatography and identified as pharbitin, a crude resin glycoside, by instrumental analysis. The antibacterial activity of pharbitin was tested in vitro against 14 phytopathogenic bacteria, and it was found to inhibit Ralstonia solanacearum and four Xanthomonas species. The minimum inhibitory concentration values against the five bacteria were $125-500{\mu}g/ml$ for the n-butanol layer and $31.25-125{\mu}g/ml$ for pharbitin. In a detached peach leaf assay, it effectively suppressed the development of bacterial leaf spot, with a control value of 87.5% at $500{\mu}g/ml$. In addition, pharbitin strongly reduced the development of bacterial wilt on tomato seedlings by 97.4% at $250{\mu}g/ml$, 7 days after inoculation. These findings suggest that the crude extract of P. nil seeds can be used as an alternative biopesticide for the control of plant diseases caused by R. solanacearum and Xanthomonas spp. This is the first report on the antibacterial activity of pharbitin against phytopathogenic bacteria.

Conceptual Design of a Portal System for International Shipping's Greenhouse Gas Monitoring, Reporting, and Verification (MRV 규제 대응을 위한 국제해운 에너지 효율 포탈 시스템 개념 설계)

  • Kang, Nam-seon;Lee, Beom-seok;Kim, Sang-yong;Lee, Jung-jin;Yoon, Hyeon-kyu
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.1
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    • pp.108-117
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    • 2016
  • In this paper, a portal system compatible with MRV regulation was designed to monitoring, reporting and verifying $CO_2$ emission and fuel consumption data from an international ship. A portal system supports monitoring and reporting task of international shipping companies and calculates national greenhouse gas inventory. EU MRV law, MRV discussions of IMO, responses of international shipping companies to ship energy efficiency and greenhouse gas regulation, and greenhouse gas statistics on international shipping were analyzed to drive portal system requirements. For ship energy efficiency and $CO_2$ emitted monitoring, a data collection module was designed based on on-board equipment, energy efficiency measuring device and navigation report. Data transfer module with easy management and minimized usage to transfer ship data to shore was designed. A portal system was designed to convert the collected data into the standard reporting format, perform monitoring, statical analysis, verification and auto report generation, and support national greenhouse gas inventory.

Alveolar Cleft Reconstruction Using Chin Bone and Autogenous Tooth Bone Graft Material: Reports of 5 Cases

  • Jeong, Kyung-In;Lee, Junho;Kim, Kyung-Wook;Um, In-Woong;Hara, Shingo;Mitsugi, Masaharu;Kim, Young-Kyun
    • Journal of Korean Dental Science
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    • v.6 no.1
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    • pp.13-21
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    • 2013
  • Purpose: To report the successful results of using chin bone graft and autogenous tooth bone graft material (AutoBT) in alveolar cleft patients. Materials and Methods: Five patients with alveolar cleft defects underwent alveolar bone grafting. Three patients were treated using chin bone graft, and the other two patients underwent AutoBT graft. After implant site development using chin bone graft in the fi rst three cases, endosseous implant restorations were placed. In case #4 and 5, AutoBT graft material was placed to guide the normal eruption of partially impacted maxillary right canine and to the upper docking site after distraction osteogenesis. Result: Successful implant restorations with closure of the oronasal fistula were achieved in alveolar cleft defect reconstruction using either chin bone graft (Case #1, 2, 3) or AutoBT graft material (Case #4, 5). Case #4 showed enlarged follicle of the right maxillary canine, indicating a normal eruption guide pattern. Conclusion: Both chin bone graft and AutoBT graft showed favorable outcomes in reconstructing alveolar cleft defects. Autogenous tooth bone graft opens up the possibility of avoiding harvesting autogenous bone graft with complications and morbidities.

Early Vegetational Succession of Burned Area in Mt. Ssalibagu (싸리바구山 山火跡地의 初期植生 邊移)

  • Kim, Jong Hong;Han Sung Jang
    • The Korean Journal of Ecology
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    • v.8 no.2
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    • pp.109-117
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    • 1985
  • This report is a part of the investigations of the secondary vegetation successions carried out and the analysis of soil properties in the burned areas of forest. The fires-crown fire and surface fire-were occurred at April, 1978 and February, 1984. The investigations were carrited out from August 10. 1983 to September 25, 1984. The burned areas studied are located in southern slope of Mt. Ssalibagu (above sea-level, 590m), So-myon, Sungju-gun, Chollanam-do, Korea. The results are as follows: The floristic compositions of the burned area at the 5th year after the fires were 85 families, 250 genera, 321 species and 53 varieties. Among them, 85 families, 127 genera, 129 species and 30 varieties were found in the currently burned area. In all the sampling sites (10*10cm), 31 and 57 species were found in the currently burned and in the 5th years after the fires, respectively. Miscanthus sinensis var. purpurascens, Quercus serrata and Festuca ovina were dominant species in the both areas. Biological spectra in both the burned areas showed $H-D_1-R_5-e$ type. Degree of the succession(DS) was 412-884 in the 5th years passed burned area and it was high level. Species diversity index(H) was 0.59~1.13 and evennes index(e) was 0.43~0.79, these indexes between both areas were different considerably. Indexes of similarity between both areas were different, too, but that between $B_1$ and $B_6$ was the highest (CCj=0.5). Probably this phenomenon is due to the great numbers of the pine trees appeared simulataneously. Content of the organic matter, N, P, K and Ca of soil in the burned area at the 5th years after the fires was lower than that of soil in the currently burned area.

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Accelerated Resting-State Functional Magnetic Resonance Imaging Using Multiband Echo-Planar Imaging with Controlled Aliasing

  • Seo, Hyung Suk;Jang, Kyung Eun;Wang, Dingxin;Kim, In Seong;Chang, Yongmin
    • Investigative Magnetic Resonance Imaging
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    • v.21 no.4
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    • pp.223-232
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    • 2017
  • Purpose: To report the use of multiband accelerated echo-planar imaging (EPI) for resting-state functional MRI (rs-fMRI) to achieve rapid high temporal resolution at 3T compared to conventional EPI. Materials and Methods: rs-fMRI data were acquired from 20 healthy right-handed volunteers by using three methods: conventional single-band gradient-echo EPI acquisition (Data 1), multiband gradient-echo EPI acquisition with 240 volumes (Data 2) and 480 volumes (Data 3). Temporal signal-to-noise ratio (tSNR) maps were obtained by dividing the mean of the time course of each voxel by its temporal standard deviation. The resting-state sensorimotor network (SMN) and default mode network (DMN) were estimated using independent component analysis (ICA) and a seed-based method. One-way analysis of variance (ANOVA) was performed between the tSNR map, SMN, and DMN from the three data sets for between-group analysis. P < 0.05 with a family-wise error (FWE) correction for multiple comparisons was considered statistically significant. Results: One-way ANOVA and post-hoc two-sample t-tests showed that the tSNR was higher in Data 1 than Data 2 and 3 in white matter structures such as the striatum and medial and superior longitudinal fasciculus. One-way ANOVA revealed no differences in SMN or DMN across the three data sets. Conclusion: Within the adapted metrics estimated under specific imaging conditions employed in this study, multiband accelerated EPI, which substantially reduced scan times, provides the same quality image of functional connectivity as rs-fMRI by using conventional EPI at 3T. Under employed imaging conditions, this technique shows strong potential for clinical acceptance and translation of rs-fMRI protocols with potential advantages in spatial and/or temporal resolution. However, further study is warranted to evaluate whether the current findings can be generalized in diverse settings.

CLINICAL STUDY ON USE OF BIODEGRADABLE PLATE AND SCREW IN ORTHOGNATHIC SURGERY (턱교정 수술에 있어 흡수성 고정판 및 나사 사용에 대한 임상적 연구)

  • Park, Sung-Soo;Choi, Jin-Young
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.31 no.2
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    • pp.127-135
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    • 2009
  • Objectives : The titanium fixation system has been used in orthognathic surgery for fixation of bone segments usually, but the biodegradable fixation system was developed and also being used. The strongest point in the biodegradable system is that no extra operation should be needed to remove fixation materials. In spite of this merit, oral & maxillofacial surgeons hesitate to use this system in fracture or orthognathic surgery. In this study, as we got some clinical experiences, we'd like to report the result of clinical study using the biodegradable fixation system in orthognathic surgery. Patients and Methods : A total of 35 patients composed of 17 males and 18 females with 25 osteotomies in maxilla and 34 osteotomies in mandible were fixated with the biodegradable fixation system(Inion $CPS^{(R)}$). We investigated methods of stabilization, fixation time, and complications on the basis of the method as above. Results : Four 2mm thick L shaped plates with 7 holes of which 1 hole was removed were fixed in maxilla with six $2.0{\times}7mm$ screws. Three $2.5{\times}16{\sim}18mm$ screws were used to fix superior ramus area and one mandibular angle area in mandible. It took about 27.4 minutes in maxilla, 25.3 minutes in mandible to perform the fixation which took longer time than the titanium system(9.5 minutes in maxilla, 8 minutes in mandible). Generally, there was no problem except 9 cases in which there were some complications. Conclusions : In most cases, the biodegradable fixation system can be used without problem in usual orthognathic surgery. But, this system is inferior to the titanium fixation one in some respects such as fixation time, size, and physical property. Some supplementations for such weak points as aforementioned should be needed for the universal use of biodegradable materials.

A SUPER-JUPITER MICROLENS PLANET CHARACTERIZED BY HIGH-CADENCE KMTNET MICROLENSING SURVEY OBSERVATIONS OF OGLE-2015-BLG-0954

  • SHIN, I.-G.;RYU, Y.-H.;UDALSKI, A.;ALBROW, M.;CHA, S.-M.;CHOI, J.-Y.;CHUNG, S.-J.;HAN, C.;HWANG, K.-H.;JUNG, Y.K.;KIM, D.-J.;KIM, S.-L.;LEE, C.-U.;LEE, Y.;PARK, B.-G.;PARK, H.;POGGE, R.W.;YEE, J.C.;PIETRUKOWICZ, P.;MROZ, P.;KOZLOWSKI, S.;POLESKI, R.;SKOWRON, J.;SOSZYNSKI, I.;SZYMANSKI, M.K.;ULACZYK, K.;WYRZYKOWSKI, L.;PAWLAK, M.;GOULD, A.
    • Journal of The Korean Astronomical Society
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    • v.49 no.3
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    • pp.73-81
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    • 2016
  • We report the characterization of a massive (mp = 3.9±1.4Mjup) microlensing planet (OGLE-2015-BLG-0954Lb) orbiting an M dwarf host (M = 0.33 ± 0.12M) at a distance toward the Galactic bulge of $0.6^{+0.4}_{-0.2}kpc$, which is extremely nearby by microlensing standards. The planet-host projected separation is a⊥ ~ 1.2AU. The characterization was made possible by the wide-field (4 deg2) high cadence (Γ = 6 hr–1) monitoring of the Korea Microlensing Telescope Network (KMTNet), which had two of its three telescopes in commissioning operations at the time of the planetary anomaly. The source crossing time t* = 16 min is among the shortest ever published. The high-cadence, wide-field observations that are the hallmark of KMTNet are the only way to routinely capture such short crossings. High-cadence resolution of short caustic crossings will preferentially lead to mass and distance measurements for the lens. This is because the short crossing time typically implies a nearby lens, which enables the measurement of additional effects (bright lens and/or microlens parallax). When combined with the measured crossing time, these effects can yield planet/host masses and distance.