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검색결과 148건 처리시간 0.02초

Earlier treatment improves the chances of complete relief from postherpetic neuralgia

  • Kang, Dong Hee;Kim, Su Young;Kim, Hyuck Goo;Park, Jung Hyun;Kim, Tae Kyun;Kim, Kyung Hoon
    • The Korean Journal of Pain
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    • 제30권3호
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    • pp.214-219
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    • 2017
  • Background: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. Methods: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years. The responders were defined as patients who had complete relief from pain after 1 year of active treatment. Age, sex, PHN duration at their first visit, dermatomal distribution, and underlying disorders were compared in the responder and non-responder groups. Responders were also compared according to these factors. Results: Among 117 PHN patients (M/F = 48/69), 35 patients (29.9%) had complete relief from PHN. Mean ages were $64.3{\pm}10.6$ and $66.9{\pm}10.7$ years, numbers of male to female patients were 11/24 and 37/45, and mean durations of PHN at their first visit were $8.5{\pm}6.3$ and $15.3{\pm}10.7$ months in the responder and non- responder groups, respectively. In addition, PHN patients who visited the clinic before 9 months showed a better result. Dermatomal distribution and underlying disorders did not show significant differences. Conclusions: Almost 30% of PHN patients received complete relief. Those who sought treatment in a pain clinic before 9 months received a better result.

Cell Image Processing Methods for Automatic Cell Pattern Recognition and Morphological Analysis of Mesenchymal Stem Cells - An Algorithm for Cell Classification and Adaptive Brightness Correction -

  • Lim, Kitaek;Park, Soo Hyun;Kim, Jangho;SeonWoo, Hoon;Choung, Pill-Hoon;Chung, Jong Hoon
    • Journal of Biosystems Engineering
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    • 제38권1호
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    • pp.55-63
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    • 2013
  • Purpose: The present study aimed at image processing methods for automatic cell pattern recognition and morphological analysis for tissue engineering applications. The primary aim was to ascertain the novel algorithm of adaptive brightness correction from microscopic images for use as a potential image analysis. Methods: General microscopic image of cells has a minor problem which the central area is brighter than edge-area because of the light source. This may affect serious problems to threshold process for cell-number counting or cell pattern recognition. In order to compensate the problem, we processed to find the central point of brightness and give less weight-value as the distance to centroid. Results: The results presented that microscopic images through the brightness correction were performed clearer than those without brightness compensation. And the classification of mixed cells was performed as well, which is expected to be completed with pattern recognition later. Beside each detection ratio of hBMSCs and HeLa cells was 95% and 92%, respectively. Conclusions: Using this novel algorithm of adaptive brightness correction could control the easier approach to cell pattern recognition and counting cell numbers.

EndoVac®과 EndoActivator®를 이용한 근관세척법의 Enterococcus faecalis 제거 효율 평가 (EVALUATION OF ENTEROCOCCUS FAECALIS REMOVAL EFFICACY OF THE ENDOVAC® AND ENDOACTIVATOR® INTRACANAL IRRIGATION METHODS)

  • 송승곤;박세희;조경모;김진우
    • Restorative Dentistry and Endodontics
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    • 제34권5호
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    • pp.390-396
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    • 2009
  • 이 실험의 목적은 $EndoVac^{(R)}$$EndoActivator^{(R)}$를 이용한 근관세척시 근관 내 접종된 Enterococcus faecalis의 제거 효율을 기존의 irrigation needle을 이용한 방법과 비교 평가하고자 함이다. 발거된 70개의 단근치를 사용하였으며 .04 taper ProFile #40까지 근관형성 후 치아를 멸균하고 근관에 E. faecalis를 접종하고 배양하였다. 치아는 근관세척 방법에 따라 20개씩 3개의 실험군과 2개의 대조군으로 나누었다. 2.5% 치아염소산나트륨을 사용하여 근관세척 시행 후 일차 표본을 채취하였고, 다시 근관 내에 배양액을 채우고 24시간 동안 배양 후 이차 표본을 채취하였다. 표본은 colony forming units (CFU) 값을 얻기 위해 BHI agar plate에 배양하였다. 일차 표본 결과에서는 모든 실험치아 중 기존의 근관세척 방법을 이용한 하나의 근관에서 양성 배양을 보였다. 이차 표본 결과에서는 $EndoVac^{(R)}$ 실험군에서 가장 적은 양성 배양을 보였으며, 기존의 근관세척 방법과 비교시 통계적으로 유의한 차이를 보였다. 실험 결과에 따르면 $EndoVac^{(R)}$은 근관 내 접종된 E. faecalis의 제거에 있어 기존의 근관세척 방법보다 더 좋은 효율을 보였다.

Delaire 개념에 기반한 선천성 구순열의 치료 ; 구순 비근육과 비중격의 정상 해부학적 구조 및 생리기전 (Congenital Cleft Lip Repair Based on Delaire Philosophy I ; Normal Anatomy and Physiology of the Labionasal Musculature and the Medial Septum of the Nose)

  • 유명숙;어미영;이석근;이종호;김성민
    • 대한구순구개열학회지
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    • 제12권2호
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    • pp.73-84
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    • 2009
  • The treatment of cleft lip and palate must be based on a complete knowledge of the anatomy, physiology and growth of the involved deformity, because of not only the appearance but also impaired functions such as phonation, mastication, respiration and lingual posture of the maxillomandibular complex. Delaire has long studied all these aspects, and has published many numbers of articles and constructed a philosophy concerning the significance and interrelationship of the various structures. The results obtained from its application seem to be particularly valid from a clinical point of view, although it has not all been scientifically supported by experimental data. For these reasons, Delaire's primary unilateral and bilateral cheilorhinoplasty procedures are particulary good, as is his secondary gingivoalveoloplsty procedure during the course of the surgical repair of the hard palate. In order to understand Delaire's philosophy, it is necessary to consider the normal and pathologic anatomy of the structures involved in the deformity, the role of some structures, such as nasal septum, musculature, and tongue, and some functions, such as dental occlusion or nasal respiration, which play important roles in maxillary and particularly premaxillary growth. Despite of important concept and meanings, Delaire's philosophy has not been introduced widely to our Korean cleft surgeons yet. So authors will summarize the basic concepts of Delaire's philosophy according to already published literatures and lectures based on our previous treatment outcomes.

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화학물질 관리 연구-1. 산업안전보건법상 관리 화학물질의 특성과 노출기준 비교 (Study on the Chemical Management - 1. Chemical Characteristics and Occupational Exposure Limits under Occupational Safety and Health Act of Korea)

  • 박지훈;함승헌;김선주;이권섭;하권철;박동욱;윤충식
    • 한국산업보건학회지
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    • 제25권1호
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    • pp.45-57
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    • 2015
  • Objectives: This study aims to compare the physicochemical characteristics, toxicological data with Occupational Exposure Limits (OELs) of chemicals under the Occupational Safety and Health Act(OSHA) regulated by the Ministry of Employment and Labor of Korea. Methods: Information on chemicals which have OELs on physicochemical characteristics and toxicological data was collected using Material Safety Data Sheet(MSDS) from Korea Occupational Safety and Health Agency(KOSHA) and the Korea Information System for Chemical Safety Management(KISChem) in 2014. Statistical analyses including correlation and simple regression were performed to compare the OELs with chemical characteristics including molecular weight, boiling point, odor threshold, vapor pressure, vapor density, solubility and octanol-water partition coefficient(OWPC) and toxicological data such as median lethal dose($LD_{50}$) and median lethal concentration($LC_{50}$). Results: A total of 656 chemicals have OELs under OSHA in Korea. The numbers of chemicals which have eight-hour time weighted average(TWA) and short term exposure limits(STEL) are 618 and 190, respectively. TWA was significantly correlated with boiling point and STEL was only correlated with vapor pressure among physicochemical characteristics. Solubility and OWPC between "skin" and "no skin" substances which indicate skin penetration were not significantly different. Both $LD_{50}$ and $LC_{50}$ were correlated with TWA, while the $LC_{50}$ was not with STEL. As health indicators, health rating and Emergency Response Planning Guidelines(ERPG) rating as recommended by the National Fire Protection Association(NFPA) and American Industrial Hygiene Association(AIHA) were associated with OELs and reflect the chemical hazards. Conclusions: We found relationships between OEL and chemical information including physicochemical characteristics and toxicological data. The study has an important meaning for understanding present regulatory OELs.

동측성 반맹시 환자의 재활치료용 시분할 장치 개발에 관한 연구 (Study on Developing the Equipment of the Time Division System for Rehabilitation in People with Homonymous Hemianopia)

  • 서재명;박근호;허민영;정주현
    • 한국안광학회지
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    • 제19권3호
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    • pp.407-412
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    • 2014
  • 목적: 시분할 장치가 동측성 반맹시 환자의 재활치료용 프레넬 프리즘으로 인한 복시 현상을 최소화하고 안정적인 시야를 확보할 수 있는지 알아보고자 하였다. 방법: 소형 모터와 마분지를 사용하여 시분할 장치를 제작했다. 시분할 장치의 효율성을 검증하기 위해 시분할 장치 전후 걷는 방향과 문자에 대한 인식을 비교 분석했다. 결과: 공간의 이등분할 실험에서 시분할 장치 전 피검자의 방향각은 $+18.14^{\circ}$였으며 장치 후의 방향각은 $+8.91^{\circ}$로 나타났다. 시분할 장치 후 $4{\times}4$시표의 문자 인식 실험에서는 정답률이 9%P, $6{\times}6$시표에서는 15%P가 증가했다. 특히 정답률이 낮은 군에서 효과가 더 뛰어났다. 결론: 시분할 장치는 동측성 반맹시 환자의 방향성이나 운동성에도 좋은 결과를 보였다.

침자극(鍼刺戟)이 생식능력(生殖能力) 저하(低下) 닭에 미치는 영향(影響) (Effect of veterinary acupuncture (VA) on the eggs-laying rate)

  • 강대희;손양선;류연희;전익수;박히준;임사비나
    • Korean Journal of Acupuncture
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    • 제20권3호
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    • pp.1-8
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    • 2003
  • Objectives : To investigate the increasing effect of veterinary acupuncture (VA) on the eggs-laying rate, we carried out the experiment in old hens. Methods : Twenty four old hens (ISA Brown; 1,200 - 1,400 g) over 75 weeks old whose eggs-laying rates were under the 50% for recent 15 days were used. In experimental group, VA treatments were performed seven times during 10 days. Unang point at the end of bilateral wing and Migun point at the tail bone were stimulated about 30 seconds by the stainless steel needle (0.3 mm o.d.). In control group, similar manual stress were performed at same frequency. The numbers of laid eggs were observed for 26 days after the beginning of treatment. Bloods were sampled two times from wing veins during and after the treatment period and serum concentrations of luteinizing hormone (LH) and Estradiol were detected. Results : Eggs-laying rates of experimental group $(34.29{\pm}2.79%)$ were significantly increased than that of control group $(27.56{\pm}2.00%,\;p<0.05)$ with the significant increasing of LH serum concentration in experimental group $(from\;0.77{\pm}0.13\;IU/I\;to\; 1.42{\pm}0.22\;IU/I,\;p<0.05)$. Conclusions : Increasing effect of VA treatment on the eggs-laying rate in old hens were proved in this study, and it may be the first prompt on the experimental investigation and development of VA.

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A GENERIC RESEARCH ON NONLINEAR NON-CONVOLUTION TYPE SINGULAR INTEGRAL OPERATORS

  • Uysal, Gumrah;Mishra, Vishnu Narayan;Guller, Ozge Ozalp;Ibikli, Ertan
    • Korean Journal of Mathematics
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    • 제24권3호
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    • pp.545-565
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    • 2016
  • In this paper, we present some general results on the pointwise convergence of the non-convolution type nonlinear singular integral operators in the following form: $$T_{\lambda}(f;x)={\large\int_{\Omega}}K_{\lambda}(t,x,f(t))dt,\;x{\in}{\Psi},\;{\lambda}{\in}{\Lambda}$$, where ${\Psi}$ = and ${\Omega}$ = stand for arbitrary closed, semi-closed or open bounded intervals in ${\mathbb{R}}$ or these set notations denote $\mathbb{R}$, and ${\Lambda}$ is a set of non-negative numbers, to the function $f{\in}L_{p,{\omega}}({\Omega})$, where $L_{p,{\omega}}({\Omega})$ denotes the space of all measurable functions f for which $\|{\frac{f}{\omega}}\|^p$ (1 ${\leq}$ p < ${\infty}$) is integrable on ${\Omega}$, and ${\omega}:{\mathbb{R}}{\rightarrow}\mathbb{R}^+$ is a weight function satisfying some conditions.

우리나라 육상 중역기점 전이

  • 최광선;옥수석;원지훈
    • 지구물리
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    • 제4권2호
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    • pp.121-131
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    • 2001
  • 2대의 중력계를 이용하여 우리나라의 88개 기상관서 내에 중력 보조점을 설치하고 GPS 측량을 실시하였다. 모든 중력 보조점의 중력치는 부산대학교 내의 중력기준점을 기준으로 측정하여, 향후 새로운 절대중력기점 값으로 쉽게 환산할 수 있도록 하였다. 이러한 중력기준망의 확장은 중력의 측정과 drift 보정 등에 의해 나타나는 오차를 최소화하여 중력 자료의 정밀도를 증대할 것이다. 또한 이 연구 결과는 상대중력계에 이해 계산된 중력 자료의 검증 및 상대중력계의 점검 등에 활용 될 수 있을 것으로 기대된다.

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Community Model for Smart TV over the Top Services

  • Pandey, Suman;Won, Young Joon;Choi, Mi-Jung;Gil, Joon-Min
    • Journal of Information Processing Systems
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    • 제12권4호
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    • pp.577-590
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    • 2016
  • We studied the current state-of-the-art of Smart TV, the challenges and the drawbacks. Mainly we discussed the lack of end-to-end solution. We then illustrated the differences between Smart TV and IPTV from network service provider point of view. Unlike IPTV, viewer of Smart TV's over-the-top (OTT) services could be global, such as foreign nationals in a country or viewers having special viewing preferences. Those viewers are sparsely distributed. The existing TV service deployment models over Internet are not suitable for such viewers as they are based on content popularity, hence we propose a community based service deployment methodology with proactive content caching on rendezvous points (RPs). In our proposal, RPs are intermediate nodes responsible for caching routing and decision making. The viewer's community formation is based on geographical locations and similarity of their interests. The idea of using context information to do proactive caching is itself not new, but we combined this with "in network caching" mechanism of content centric network (CCN) architecture. We gauge the performance improvement achieved by a community model. The result shows that when the total numbers of requests are same; our model can have significantly better performance, especially for sparsely distributed communities.