• Journal of Ginseng Research
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• v.42 no.4
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• pp.524-531
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• 2018

Background: Fermented black ginseng (FBG) is produced through several cycles of steam treatment of raw ginseng, at which point its color turns black. During this process, the original ginsenoside components of raw ginseng (e.g., Re, Rg1, Rb1, Rc, and Rb2) are altered, and less-polar ginsenosides are generated (e.g., Rg3, Rg5, Rk1, and Rh4). The aim of this study was to determine the effect of FBG on wound healing. Methods: The effects of FBG on tube formation and on scratch wound healing were measured using human umbilical vein endothelial cells (HUVECs) and HaCaT cells, respectively. Protein phosphorylation of mitogen-activated protein kinase was evaluated via Western blotting. Finally, the wound-healing effects of FBG were assessed using an experimental cutaneous wounds model in mice. Results and Conclusion: The results showed that FBG enhanced the tube formation in HUVECs and migration in HaCaT cells. Western blot analysis revealed that FBG stimulated the phosphorylation of p38 and extracellular signal-regulated kinase in HaCaT cells. Moreover, mice treated with $25{\mu}g/mL$ of FBG exhibited faster wound closure than the control mice did in the experimental cutaneous wounds model in mice.

• Journal of Korean Academy of Nursing
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• v.40 no.4
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• pp.551-560
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• 2010

Purpose: The purpose of this present study was to develop and evaluate the psychometric properties of a needs scale for patients with cancer undergoing follow-up care (NS-C). Methods: A preliminary NS-C of 48 was derived from literature reviews and in-depth interviews with patients with cancer. Content validation of the items was established by oncology physicians and nurses. Each item was scored on a five-point Likert scale. The preliminary NS-C and Eastern Cooperative Oncology Group (ECOG) performance status questionnaires were administered to 873 patients with cancer recruited from three university hospitals. The data were analyzed using factor analysis, multidimensional scaling analysis, ANOVA, Pearson correlation coefficients, and Cronbach's alpha. Results: From the factor analysis, 25 significant items in six subscales were derived. The subscales were named physical symptoms, diet and exercise, support, relationship with health professionals, treatment/prognosis, and keeping mind under control. The NS-C also established item convergent and discriminant validity, and known-groups validity. Cronbach's alpha of the subscales ranged from .90 to .92. Conclusion: This study suggests that the NS-C is an easy, reliable and valid instrument to measure the needs of patients with cancer. Health professionals may use the NS-C for patients with cancer both in practice and research.

• Journal of Digital Convergence
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• v.15 no.3
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• pp.39-46
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• 2017

This study investigates the problems resulting from the Internet addiction policy management in South Korea and discusses a direction for rational policies by developing a system that facilitates interactive discussions among interest individuals and groups. The Korean society has experienced conflicts of interests among the government, the private sector and civil society in the policy. In addition, heightened competition among government ministries has led the Internet addiction policy management to be susceptible to how citizens respond to the claims of interested parties, thereby having the rationality of the policy management less count. To address these issues, this study investigates the current Internet addiction policy and explores the potential of new governance from a perspective of new institutionalism. This study suggests that the system of the Internet addiction policy should be restructured to transfer control over the policy from the central to local government and develop governance centered on the consensus of the government, the private sector, and civil society.

• BMB Reports
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• v.41 no.12
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• pp.868-874
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• 2008

Neurofilaments (NFs) are neuronal intermediate filaments composed of light (NF-L), middle (NF-M), and heavy (NF-H) subunits. NF-L self-assembles into a "core" filament with which NF-M or NF-H co-assembles to form the neuronal intermediate filament. Recent reports show that point mutations of the NF-L gene result in Charcot-Marie-Tooth disease (CMT). However, the most recently described rod domain mutant of human NF-L (A148V) has not been characterized in cellular level. We cloned human NF-L and used it to engineer the A148V. In phenotypic analysis using SW13 cells, A148V mutation completely abolished filament formation despite of presence of NF-M. Moreover, A148V mutation reduced the levels of in vitro self-assembly using GST-NF-L (H/R) fusion protein whereas control (A296T) mutant did not affect the filament formation. These results suggest that alanine at position 148 is essentially required for NF-L self-assembly leading to subsequent filament formation in neuronal cells.

• Journal of the Korean Institute of Gas
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• v.19 no.5
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• pp.98-103
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• 2015

Liquefied petroleum gas can be charged up to 85% of cylinder volume by enforcement regulations of safety control and business of liquefied petroleum gas act. The charged mass by enforcement regulations is considered by liquid expansion of internal liquefied petroleum gas at $65^{\circ}C$. But the temperature of liquid would not be suspended under $65^{\circ}C$ in a cylinder or portable vessel at certain situation. In the thermodynamics view point, the cylinder can be exposed to high pressure by liquid expansion. Consequently, it can be possible to potential risk such as physical explosion. Hence, this paper will offer a method of estimated internal pressure by liquid expansion at critical state in the closed system. Also, the structural factor which is given rise to volume increasement of cylinder is offered by experiment. This paper is expected as crucial reference for a cylinder design of liquefied petroleum gas.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2006.10a
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• pp.157-165
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• 2006

In February,2004, at International Maritime Organization (IMO), LONDON, a new international convention 'International Convention fur the Control and Management of Ship's Ballast Water and Sediment 2004' was adopted. It is called 'Ballast Water Management Convention (BWM)'. Ballast water means charged seawater or fresh water in ship's special tanks (ballast tank) to keep safety navigation and ship's maneuverability. However, from 1980, it was point out the serious problem for marine ecosystem and human life that ballast water includes harmful marine species (and small organisms) and these species are also discharged along with ballast water. These species were released with discharged ballast water in water areas, where species are different from discharged ballast water. The problem is that released species increase when released species are more powerful than native species and consequently, marine ecological system is destroyed in released water area. Authors have inspected the validity of the ballast water exchange using pumping-through method that is one of the methods of ballast water management. In this paper, the numerical simulation of the motion and density of the fluid at the time of exchange of the fluid in a 2-dimensional tank using the pumping-through method was carried out by using two different type numerical methods. One method is MPS method that is one of the particle methods. Other one is Finite Different Method (FDM). Authors were compared with result of two numerical method calculations and experiment result and reported some knowledge from these results.

• Journal of the Korean Institute of Navigation
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• v.10 no.1
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• pp.101-127
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• 1986

Transportation provides an infrastructure vital to economic growth, and it is an integral part of production . As a port is the interface between the maritime transport and domestic transport sectors, it certainly plays a key role in any economic development. Therefore, it is doubtless that inadequacy of a nation's port will depress the level of throughput, to the level where it fails to meet the target set by the national economic planning schemes. Korea is surrounded by the seas and the economic structure of Korea consists of processing trades, so that it cannot be overstated that substantial economy in maritime transport coasts can be achieved through the improvement of the port transport system. This paper treats the transportation process in Pusan Port by Queueing Simulation method, and the reasonable size of Pusan Port is suggested from the point of view of efficiency maximization. The results of the analysis are summarized as follows; 1) the utility rate is 47.91 percents in general piers, 85-52 percents in container piers, and waiting time 5.2hrs, in general piers, 0.8 hrs, in container piers, and the probability of maximum queue length 12 ships in general piers, 2 ships in container piers, and the probability of waiting is 44 percents in general piers, 8 percents in container pier. 2) in general piers, the improvement of app. 30 percents in port capacity is desirable for operating effectively concerning the current arrival rate. By introducing the traffic control ion container piers, there is no apparent necessity of port investment, but I is expected to reduce invisible congestion occurred along the waiting line. 3) On Pusan Port, the optimal utility rate and the optimal arrival rate for reducing waiting time are 3.5 to 4.0(hrs./ship) in general piers, 5.1 to 6.0(hrs./ship) in container piers.

• Korean Journal of Medicinal Crop Science
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• v.23 no.2
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• pp.161-167
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• 2015

This study was carried out to determine the effects of light controls and leaf mold on root growth and physiological responses of Atractylodes japonica growing in forest farming. The experiment was performed by light controls (100%, 62.5%, 40.3% and 19.7% of full sunlight) and application of leaf mold to soil. Height, stem diameter, number of flower buds and root collar diameter were the highest in leaf mold within 62.5% of full sunlight (relative light intensity 62.5%). And these were the higher in leaf mold within each light level. As the shading level increased, light saturation point and maximum photosynthesis rate decreased. As the light level decreased, SPAD value increased in control and leaf mold. As a result of surveying the whole experiment, A. japonica was judged worse root growth under the lower light level. It was concluded that the light level was one of the most important factors to produce A. japonica. Also, producing high-quality of A. japonica with the price competitiveness by using leaf mold like the experiment can be an effective way to increase incomes for farmers.

• Korean Journal of Geomatics
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• v.2 no.1
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• pp.47-55
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• 2002

Remote sensing is the science and art of obtaining information about an object, area or phenomenon through the analysis of data acquired by a device that is not in contact with the object, area, or phenomenon under investigation./sup 1)/ EOC (Electro -Optical Camera) sensor loaded on the KOMPSAT-1 (Korea Multi- Purpose Satellite-1) performs the earth remote sensing operation. EOC can get high-resolution images of ground distance 6.6m during photographing; it is possible to get a tilt image by tilting satellite body up to 45 degrees at maximum. Accordingly, the device developed in this study enables to obtain images by photographing one pair of tilt image for the same point from two different planes. KOMPSAT-1 aims to obtain a Korean map with a scale of 1:25,000 with high resolution. The KOMPSAT-1 developed automated feature extraction system based on stereo satellite image. It overcomes the limitations of sensor and difficulties associated with preprocessing quite effectively. In case of using 6, 7 and 9 ground control points, which are evenly spread in image, with 95% of reliability for horizontal and vertical position, 3-dimensional positioning was available with accuracy of 6.0752m and 9.8274m. Therefore, less than l0m of design accuracy in KOMPSAT-1 was achieved. Also the ground position error of ortho-image, with reliability of 95%, is 17.568m. And elevation error showing 36.82m was enhanced. The reason why elevation accuracy was not good compared with the positioning accuracy used stereo image was analyzed as a problem of image matching system. Ortho-image system is advantageous if accurate altitude and production of digital elevation model are desired. The Korean map drawn on a scale of 1: 25,000 by using the new technique of KOMPSAT-1 EOC image adopted in the present study produces accurate result compared to existing mapping techniques involving high costs with less efficiency.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.3
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• pp.86-97
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• 2021

As mechatronic systems have various, complex functions and require high performance, automatic fault detection is necessary for secure operation in manufacturing processes. For conducting automatic and real-time fault detection in modern mechatronic systems, multiple sensor signals are collected by internet of things technologies. Since traditional statistical control charts or machine learning approaches show significant results with unified and solid density models under normal operating states but they have limitations with scattered signal models under normal states, many pattern extraction and matching approaches have been paid attention. Signal discretization-based pattern extraction methods are one of popular signal analyses, which reduce the size of the given datasets as much as possible as well as highlight significant and inherent signal behaviors. Since general pattern extraction methods are usually conducted with a fixed size of time segmentation, they can easily cut off significant behaviors, and consequently the performance of the extracted fault patterns will be reduced. In this regard, adjustable time segmentation is proposed to extract much meaningful fault patterns in multiple sensor signals. By considering inflection points of signals, we determine the optimal cut-points of time segments in each sensor signal. In addition, to clarify the inflection points, we apply Savitzky-golay filter to the original datasets. To validate and verify the performance of the proposed segmentation, the dataset collected from an aircraft engine (provided by NASA prognostics center) is used to fault pattern extraction. As a result, the proposed adjustable time segmentation shows better performance in fault pattern extraction.