• The Plant Pathology Journal
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• 제30권3호
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• pp.236-244
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• 2014

The plant pathogen Fusarium graminearum causes Fusarium head blight in cereal crops and produces mycotoxins that are harmful to animals and humans. For the initiation and spread of disease, asexual and sexual reproduction is required. Therefore, studies on fungal reproduction contribute to the development of new methods to control and maintain the fungal population. Screening a previously generated transcription factor mutant collection, we identified one putative $C_2H_2$ zincfinger transcription factor, pcs1, which is required for both sexual and asexual reproduction. Deleting pcs1 in F. graminearum resulted in a dramatic reduction in conidial production and a complete loss of sexual reproduction. The pathways and gene ontology of pcs1-dependent genes from microarray experiments showed that several G-protein related pathways, oxidase activity, ribosome biogenesis, and RNA binding and processing were highly enriched, suggesting that pcs1 is involved in several different biological processes. Further, overexpression of pcs1 increased conidial production and resulted in earlier maturation of ascospores compared to the wild-type strain. Additionally, the vegetative growth of the overexpression mutants was decreased in nutrient-rich conditions but was not different from the wild-type strain in nutrient-poor conditions. Overall, we discovered that the pcs1 transcription factor positively regulates both conidiation and sexual reproduction and confers nutrient condition-dependent vegetative growth.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권5호
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• pp.301-312
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• 2020

In disease diagnostics and health surveillance, the use of saliva has potential because its collection is convenient and noninvasive. Over the past two decades, the development of salivary utilization for the early detection of cancer, especially oral cavity and oropharynx cancer has gained the interest of the researcher and clinician. Until recently, the oral cavity and oropharynx cancers are still having a five-year survival rate of 62%, one of the lowest in all major human cancers. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Despite the ease of accessing the oral cavity in clinical examination, most OSCC lesions are not diagnosed in the early stage, which is suggested to be the main cause of the low survival rate. Many studies have been performed and reported more than 100 potential saliva biomarkers for OSCC. However, there are still obstacles in figuring out the reliable OSCC salivary biomarkers and the clinical application of the early diagnosis protocol. The current review article discusses the emerging issues and is hoped to raise awareness of this topic in both researchers and clinicians. We also suggested the potential salivary biomarkers that are reliable, specific, and sensitive for the early detection of OSCC.

• 한국문헌정보학회지
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• 제52권1호
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• pp.469-490
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• 2018

본 연구의 목적은 공공도서관 상호대차서비스 데이터를 이용하여 현재 수행되는 서비스의 현황을 분석하는 것이다. 또한 분석 과정에서 서비스 수행과 관련된 이슈를 발견하고 이를 개선하기 위한 방안을 제안하는 것을 목적으로 한다. 분석을 위해 책바다 서비스 데이터와 국가도서관통계시스템 데이터, 지역 단위 상호대차서비스 현황 데이터를 수집하여 분석하였다. 연구결과, 상호대차서비스 이용은 계속적으로 증가하고 있었고 특히 지역 단위에서 운영되는 상호대차 서비스가 활발히 수행되고 있음을 알 수 있었다. 또한 상호대차서비스 요청과 제공 등의 이용뿐만 아니라 서비스 네트워크에 참여하는 도서관들의 유형이 다양하고 그 숫자도 확대되고 있는 것으로 나타났다. 덧붙여, 상호대차서비스 네트워크에서 각 도서관이 어느 정도 협력하는지를 측정하기 위한 도구의 하나로 공헌도에 대한 논의를 진행하였다. 이용과 관련된 통계뿐만 아니라 개별 도서관의 장서적인 고유성, 도서 기반의 협업 지수 등을 고려한 공헌도 분석의 필요성을 제안하였다.

• 대한간호학회지
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• 제51권4호
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• pp.478-488
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• 2021

Purpose: This study aimed to develop and examine the effects of a prenatal program on environmental health behavior using cartoon comics among Korean pregnant women. Methods: This study used a non-equivalent control group pre-test/post-test design. The program used cartoon comics to explore environmental health behaviors during pregnancy. The program consisted of the following four components: environmental toxicants during pregnancy, avoiding particulate matter during pregnancy, environmental toxicants during baby care, and making a healthy environment for children. In total, 35 pregnant women participated in the study: 18 in the experimental group and 17 in the control group. Data collection and program adaptation were conducted between November 3, 2020 and January 19, 2021. The effect of the prenatal education program was evaluated by t-test and repeated measures ANOVA. Results: Learning experience (t = - 2.35, p = .025), feasibility (t = - 2.46, p = .019), satisfaction (t = - 2.23, p = .032) were higher in the experimental group than in the control group in the first post-test. Feasibility (t = - 2.40, p = .022) was higher in the experimental group than in the control group in the second post-test. Repeated-measures ANOVA showed significant interactions between time and group in environmental susceptibility (F = 9.31, p < .001), self-efficacy (F = 3.60, p = .033), and community behavior (F = 5.41, p = .007). Conclusion: This study demonstrates the need for a prenatal education program to promote environmental health perceptions and behavior during pregnancy. We suggest a prenatal class adopting the creative cartoon comics to promote the maternal environmental health behaviors.

• Nutrition Research and Practice
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• 제16권3호
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• pp.366-378
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• 2022

BACKGROUND/OBJECTIVES: The purpose of this study was to develop a sodium index, which is a tool for estimating and assessing sodium intake easily and quickly, to assist in the prevention of various diseases induced by excess sodium intake in Korean adults. SUBJECTS/METHODS: The 24-h urine collection and dietary behavior surveys were performed on 640 healthy people in 4 regions of South Korea, and an equation for the estimation of 24-h sodium intake was developed. The validity and reliability of the equation were verified with 200 adults. The sodium index was developed by converting the estimated sodium intake using the equation. Finally, the sodium intake status of 1,600 adults was assessed using the sodium index. RESULTS: The equation included sex, age, body mass index, eating habit and dietary behaviors related to sodium intake. In validity test of the equation, the mean bias between sodium intake using 24-h urine analysis and using the equation from the Bland-Altman plots was -1.5 mg/day. The sensitivity and specificity of the equation for estimation of sodium intake were 80.5% and 64.4%, respectively. In the reliability test of the equation, there was no significant difference between the first and second sodium intakes calculated using the equations, and Spearman's correlation coefficient between the 2 sodium intakes was 0.98. Sodium intake can be assessed as 'very moderate' for 75-100 on the sodium index, 'moderate' for 100-150, 'careful' for less than 75 or 150-200, and 'severe' for 250 or more. When sodium intake was assessed using the sodium index in 1,600 subjects, 54.3% and 24.3% of the subjects were assessed to be in the 'careful' and 'severe' categories, respectively. CONCLUSIONS: Using a simple questionnaire, the sodium index can be used to monitor and assess sodium intake status, assisting in nutrition education and counseling in a large population.

• 박물관보존과학
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• 제19권
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• pp.99-116
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• 2018

국립중앙박물관은 지난 40년간 한국 보존과학의 중심 기관으로 보존처리, 분석 및 연구 등 다양한 업무를 하였다. 그러나 소장품 대비 처리 인력 부족, 장비 노후화, 외부 기관의 업무 지원 요구와 기능 강화 등의 문제점이 확인되었다. 이에 국립중앙박물관 보존과학 분야의 발전 방안을 위한 상황을 진단하고, 향후 요구되는 기능과 발전방안에 대한 연구를 수행하였다. 박물관 현황 진단 및 국외 사례 분석을 통해 보존과학이 발전하기 위한 5가지 기능을 제시하였다. 기존 보존처리 기능 및 보존과학 지원 기능의 강화가 필요하다. 또한 가치 판단을 포함한 첨단 분석 및 진단 기능, 기후 변화에 따른 박물관 보존환경 및 관리 기능, 그리고 콘텐츠를 중심으로 한 디지털 보존·복원 기능을 신설하고 확대 운영하는 방향을 제시하였다. 이상의 기능 강화 및 신규 기능 확대를 통해 국립중앙박물관 보존과학은 향후 아시아의 중심 보존과학센터로서 발전될 수 있을 것으로 기대된다.

• 대한간호학회지
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• 제44권3호
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• pp.339-349
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• 2014

Purpose: This study was done to develop a measurement for stress experienced by patients with schizophrenia during hospitalization. Methods: The preliminary tool was developed through in-depth interviews and a validity verification test of content. For data collection, 15 inpatients with schizophrenia were selected as participants for in-depth interviews and 195 patients admitted to one of eight psychiatric hospitals in four provinces were recruited as participants to test reliability and validity of the preliminary tool. Results: The questionnaire was developed as a four-point Likert-type scale in a self-report form with 28 items. Factor analysis showed 28 items in six factors. Factors were named 'Unjust human rights infringement', 'Futureless life', 'Alienation from other family members', 'Infringement of basic needs', 'Infringement of personal preference' and 'Inconvenience of shared living'. The six factors explained 63.5% of the total variance. Cronbach's alpha for the total items was .93 and for the factors ranged from .65 to .87. Conclusion: A tool to measure stress in patients hospitalized with schizophrenic was developed based on identified hospitalization stress experiences. Study results indicate that this tool can be used to evaluate hospitalization stress in these patients and will contribute to establishing nursing interventions for relief of hospitalization stress.

• 대한간호학회지
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• 제45권6호
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• pp.802-811
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• 2015

Purpose: The purpose of this study was to test and validate a model to predict living and brain death organ donation intention in nursing students. The conceptual model was based on the theory planned behavior. Methods: Quota sampling methodology was used to recruit 921 nursing students from all over the country and data collection was done from October 1 to December 20, 2013. Results: The model fit indices for the hypothetical model were suitable for the recommended level. Knowledge, attitude, subjective norm and perceived behavioral control explained 40.2% and 40.1% respectively for both living and brain death organ donation intention. Subjective norm was the most direct influential factor for organ donation intention. Knowledge had significant direct effect on attitude and indirect effect on subjective norm and perceived behavioral control. These effects were higher in brain death organ donation intention than in living donation intention. Conclusion: The overall findings of this study suggest the need to develop systematic education programs to increases knowledge about brain death organ donation. The development, application, and evaluation of intervention programs are required to improve subjective norm.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제21권2호
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• pp.125-152
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• 2007

대학수학 학습지도에서 문제풀이가 잘못된 경우를 9개 영역으로 분류하고 각 영역마다 잘못이 일어나는 과정에 대한 세부 문항과 내용을 제시하고 오류를 지적해보도록 유도하며 올바른 문제풀이에 이르는 길을 확인하는 기회를 갖도록 한다. 이들 학습자료가 주는 중요한 의미를 여덟 가지로 요약하여 대학수학의 이해에 도움을 주고 대학수학 학습의 동기부여와 흥미를 느끼도록 안내하며 잘못된 풀이나 실수의 확인이 중요함을 일깨우고 분석하게 하여 깊이 있고 여유로운 수학학습을 생각할 기회를 제공한다.

• 한국의류산업학회지
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• 제22권5호
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• pp.639-649
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• 2020

This study investigates consumer opinions of clothing care and provides fundamental data to decision-making for oncoming development of clothing care system. Textom, a web-matrix program, was used to analyze big data collected from Naver and Daum with a keyword of "clothing care" from March 2019 to February 2020. A total of 22, 187 texts were shown from the big data collection. Collected big data were analyzed using text-mining, network, and CONCOR analysis. The results of this study were as follows. First, many keywords related to clothing care were shown from the result of frequency analysis such as style, Dryer, LG Electronics, Product, Customer, Clothing, and Styler. Consumers were well recognizing and having an interest in recent information related to the clothing care system. Second, various keywords such as product, function, brand, and performance, were linked to each other which were fundamentally related to the clothing care. The interest in products of the clothing care system were linked to product brands that were also naturally linked to consumer interest. Third, the keywords in the network showed similar attributes from the result of CONCOR analysis that were classified into 4 groups such as the characteristics of purchase, product, performance, and interest. Lastly, positive emotions including goodwill, interest, and joy on the clothing care system were strongly expressed from the result of the sentimental analysis.