• Korean Journal of Bronchoesophagology
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• v.2 no.1
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• pp.120-124
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• 1996

Nasopharyngeal angiofibroma is rare highly vascular tumor and occurs almost exclusively in adolescent boy. This tumor is histologically benign but clinically malignant because of massive bleeding, destruction of surrounding tissue, difficulty in surgical access and recurrence. Preoperative embolization is required to decrease bleeding during operation Surgical method varies according to staging of angiofibroma. Recently, we had experienced a case of angiofibroma that was resected by transmaxillary approach after preoperative embolization.

• Korean Journal of Head & Neck Oncology
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• v.10 no.2
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• pp.137-144
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• 1994

To provide the wide and satisfactory surgical field is essential requirement for en-bloc resection of nasopharyngeal angiofibroma invading central skull base. The new design of the surgical approach to the skull base lesions was developed and described the details of this technique and its usefullness. We compared the usefullness of naso-maxillary approach to that of infratemporal fossa approach in cases of angiofibroma invading skull base. Our experience indicates that the naso-maxillary swing approach is better than lateral approach for the large nasopharyngeal angiofibroma. A new approach. naso-maxillary swing approach. is described.

• Journal of Yeungnam Medical Science
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• v.1 no.1
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• pp.191-197
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• 1984

Nasopharyngeal angiofibroma is a relatively rare, but is a well known tumor that occurs almost in male, most frequently during the adolescent stage. Its character is histologically benign but clinically malignant because of locally invasive character to the adjascent structures, massive bleeding tendency during surgical procedure and high recurrence rate after treatment. Recently many advancements in diagnostic method and surgical technique has reached satisfactory result in treating this difficult tumor. The authors present a case of nasopharyngeal angiofibroma in 16 years old male patient, who was received surgical removal of the tumor through the transpalatal approach after full diagnostic evaluation and preoperative hormonal therapy.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.45 no.1
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• pp.43-47
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• 2019

The characteristics of extra-nasopharyngeal angiofibromas tend to be different from angiofibromas of the nasopharynx according to patient gender, patient age, prevalence, affected site, pathogenesis, and clinical and epidemiological features. We report a case of an extra-nasopharyngeal angiofibroma in a 28-year-old man referred to the ENT Clinic for right-sided epistaxis, airflow impairment and nasal swelling. The right nostril was completely occluded works by a reddish-yellow mass that bled easily. The computed tomography scan revealed an "inhomogeneous solid lesion in the nasal fossa". With the patient under general anesthesia, the formation in the anterior portion of the right side of the nasal septum was removed up to its vascular base. Although electrical cauterization efficiently controlled the bleeding, we abraded the sub-perichondral area to prevent further bleeding as well as recurrence. The histological exam report confirmed the diagnosis of angiofibroma. As in our case, epistaxis is commonly the presenting sign of angiofibroma. Yet its onset was peculiar, given that the bleeding started with a low impact trauma. The nasal swelling was also a relevant feature as well as the breathing impairment. Although uncommon, nasal septal angiofibromas should considered in patients with epistaxis.

• Korean Journal of Head & Neck Oncology
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• v.13 no.2
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• pp.251-255
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• 1997

Although primary surgical excision is the treatment of choice for the vast majority of patients with nasopharyngeal angiofibroma, radiation therapy is also employed as a primary tool or in the cases of tumor recurrence or massive intracranial extension. But, especially in young patients, postradiation sequelae such as osteomyelitis, atrophic rhinitis, thyroid or bone malignancy are of concern. Postirradiation osteosarcoma is a rare, but well-recognized complication of radiotherapy, which comprise roughly 2 to 5 percent of all osteogenic sarcoma. Recently we experienced a case of postirradiation osteosarcoma of the mandible who had treated by radiation therapy for the nasopharyngeal angiofibroma 30 years ago, presently he is ongoing chemotherapy and relatively being well.

• Korean Journal of Head & Neck Oncology
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• v.34 no.2
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• pp.89-92
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• 2018

Malignant salivary gland tumors only represent 0.08% of all childhood tumors. Especially, nasopharyngeal mucoepidermoid carcinoma(MEC) in pediatric age is an extremely rare malignancy. We hereby report a case of nasopharyngeal MEC in 5 year-old female patient. The patient underwent the complete removal of the tumor by endonasal endoscopic approach. Adjuvant postoperative radiotherapy was not considered. After 3.5 years of follow-up, there are no sign of recurrence and metastasis. Minor salivary gland tumor must be considered as a differential diagnosis of angiofibroma in nasopharynx in pediatric age. To our knowledge, the case we describe is the third case of nasopharyngeal MEC in pediatric age reported in literature.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1987.05a
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• pp.23.2-23
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• 1987

저자들은 1977년부터 1986년까지 10년동안 서울대학병원 이비인후과에서 유년기성 비인강 혈관섬유종의 진단하에 치료받았던 27명의 환자에 대해 임상적 조사를 시행하여 다음과 같은 결과를 얻었다. 1) 남녀비율은 전례에서 남성이었으며 연령은 9세∼22세의 분포를 보였고 16∼17세가 가장 많았다. 2) 주증상으로는 전례에서 비출혈을 동반하는 비폐색증을 보였으며 편측인 례가 7례였다. 3) 종양의 크기는 21례에서 비인강 및 비강내에 국한되어 있었고, 4례에서 익상상악와, 2례에서 두개내 침습을 보였다. 4) 종양의 혈액공급은 동측의 내상악동맥에서 이루어지는 경우가 27례, 동측의 상행인두동맥이 13례, 양측에서 이루어지는 경우가 9례 있었다. 5) 치료는 23례에서 수술적 요법을, 4례에서 방사선치료를 시행하였다. 수술적 요법 23례중 11례 에서 경반구개제거술(hemipalatal approach), 8례에서 경전구개제거술(transpalatal appoach), 2례에서 경전구개 및 경상악동제거술(transantral approach), 2례에서 외비절제술(lateral rhinotomy approach)에 의해서 종양을 적출하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.20 no.4
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• pp.379-382
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• 1998

The 44 years old man was consulted to our department due to restriction of mouth opening. On radiograph, we found bony expansive lesion at right mandibular ramus and temporal bone that it was suspected malignant tumor. So we had performed incisional bone biopsy at right ramus through skin incision. The result of biopsy was osteosarcoma. Then, he had experienced radiation therapy for the protection of recurrence after several times surgery of nasopharyngeal angiofibroma, 28 years ago. So, we concluded radiation induced osteosarcoma from his radiation therapy history. He had referred to the department of hematooncology because of severe expansion to skull base and was received 4 times chemotherapy with cisplatin and adriamycin, but he was expired just after 4th chemotherapy. Such radiation induced osteosarcoma have relative good prognosis due to rare metastasis from other reports. So if it will early detect from close follow up after radiation therapy, survival rate will rise up. But we missed early detection of our case. So, we report a case of rare radiation induced osteosarcoma. Ly detection of our case.