RADIATION-INDUCED OSTEOSARCOMA : REPORT OF A CASE

방사선 치료에 의해 발생한 골육종의 치험례

  • Park, Kwan Soo (Department of Dentistry &Oral Maxillofacial surgery, Keimyung University School of Medicine) ;
  • Lee, Yong Gyoo (Department of Dentistry &Oral Maxillofacial surgery, Keimyung University School of Medicine) ;
  • Park, Hyo Sang (Department of Dentistry &Oral Maxillofacial surgery, Keimyung University School of Medicine) ;
  • Kim, Jong Bae (Department of Dentistry &Oral Maxillofacial surgery, Keimyung University School of Medicine)
  • 박관수 (계명대학교부속 동산의료원 치과-구강악안면외과) ;
  • 이용규 (계명대학교부속 동산의료원 치과-구강악안면외과) ;
  • 박효상 (계명대학교부속 동산의료원 치과-구강악안면외과) ;
  • 김종배 (계명대학교부속 동산의료원 치과-구강악안면외과)
  • Received : 1998.09.25
  • Accepted : 1998.10.26
  • Published : 1998.12.31

Abstract

The 44 years old man was consulted to our department due to restriction of mouth opening. On radiograph, we found bony expansive lesion at right mandibular ramus and temporal bone that it was suspected malignant tumor. So we had performed incisional bone biopsy at right ramus through skin incision. The result of biopsy was osteosarcoma. Then, he had experienced radiation therapy for the protection of recurrence after several times surgery of nasopharyngeal angiofibroma, 28 years ago. So, we concluded radiation induced osteosarcoma from his radiation therapy history. He had referred to the department of hematooncology because of severe expansion to skull base and was received 4 times chemotherapy with cisplatin and adriamycin, but he was expired just after 4th chemotherapy. Such radiation induced osteosarcoma have relative good prognosis due to rare metastasis from other reports. So if it will early detect from close follow up after radiation therapy, survival rate will rise up. But we missed early detection of our case. So, we report a case of rare radiation induced osteosarcoma. Ly detection of our case.

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